Sulforaphane protects cortical neurons against 5-S-cysteinyl-dopamine-induced toxicity through the activation of ERK1/2, NrF-2 and the upregulation of detoxification enzymes

Molecular Nutrition and Food Research

Volumn 54, Issue 4, 2010, Pages 532-542

  Vauzour, David ^a   Buonfiglio, Maria ^b   Corona, Giulia ^a   Chirafisi, Joselita ^a   Vafeiadou, Katerina ^a   Angeloni, Cristina ^b   Hrelia, Silvana ^b   Hrelia, Patrizia ^b   Spencer, Jeremy P E ^a  

^a UNIVERSITY OF READING   (United Kingdom)

^b UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

5 S cysteinyl dopamine; Antioxidant response element; Neurodegeneration; Parkinson's disease; Sulforaphane

Indexed keywords

5 (S CYSTEAMINYL)DOPAMINE; 5-S-CYSTEAMINYLDOPAMINE; DOPAMINE; DRUG DERIVATIVE; GLUTATHIONE; GLUTATHIONE REDUCTASE; GLUTATHIONE TRANSFERASE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; NEUROPROTECTIVE AGENT; NQO1 PROTEIN, MOUSE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); SULFORAFAN; THIOCYANIC ACID DERIVATIVE; THIOREDOXIN REDUCTASE; TRANSCRIPTION FACTOR NRF2;

ANIMAL; ARTICLE; BRAIN CORTEX; CELL CULTURE; CELL DEATH; CYTOLOGY; DRUG EFFECT; ENZYME ACTIVATION; METABOLISM; MOUSE; NERVE CELL; PHOSPHORYLATION; PHYSIOLOGY;

ANIMALS; CELL DEATH; CELLS, CULTURED; CEREBRAL CORTEX; DOPAMINE; ENZYME ACTIVATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GLUTATHIONE; GLUTATHIONE REDUCTASE; GLUTATHIONE TRANSFERASE; MICE; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; NAD(P)H DEHYDROGENASE (QUINONE); NEURONS; NEUROPROTECTIVE AGENTS; NF-E2-RELATED FACTOR 2; PHOSPHORYLATION; THIOCYANATES; THIOREDOXIN-DISULFIDE REDUCTASE;

EID: 77951076084     PISSN: 16134125     EISSN: 16134133     Source Type: Journal    
DOI: 10.1002/mnfr.200900197     Document Type: Article

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