-
1
-
-
14444267540
-
Characterization of new polyclonal antibodies specific for 40 and 42 amino acid-long amyloid beta peptides: Their use to examine the cell biology of presenilins and the immunohistochemistry of sporadic Alzheimer's disease and cerebral amyloid angiopathy cases
-
H. Barelli A. Lebeau J. Vizzavona P. Delaere N. Chevallier C. Drouot P. Marambaud K. Ancolio J. D. Buxbaum O. Khorkova J. Heroux S. Sahasrabudhe J. Martinez J. M. Warter M. Mohr F. Checler 1997 Characterization of new polyclonal antibodies specific for 40 and 42 amino acid-long amyloid beta peptides: their use to examine the cell biology of presenilins and the immunohistochemistry of sporadic Alzheimer's disease and cerebral amyloid angiopathy cases Mol Med 3 695 707
-
(1997)
Mol Med
, vol.3
, pp. 695-707
-
-
Barelli, H.1
Lebeau, A.2
Vizzavona, J.3
Delaere, P.4
Chevallier, N.5
Drouot, C.6
Marambaud, P.7
Ancolio, K.8
Buxbaum, J.D.9
Khorkova, O.10
Heroux, J.11
Sahasrabudhe, S.12
Martinez, J.13
Warter, J.M.14
Mohr, M.15
Checler, F.16
-
2
-
-
0023130372
-
Evaluation of a tetrazolium-based semiautomated colorimetric assay: Assessment of chemosensitivity testing
-
J. Carmichael W. G. DeGraff A. F. Gazdar J. D. Minna J. B. Mitchell 1987 Evaluation of a tetrazolium-based semiautomated colorimetric assay: assessment of chemosensitivity testing Cancer Res 47 936 942
-
(1987)
Cancer Res
, vol.47
, pp. 936-942
-
-
Carmichael, J.1
Degraff, W.G.2
Gazdar, A.F.3
Minna, J.D.4
Mitchell, J.B.5
-
4
-
-
0033054564
-
C-terminal maturation fragments of presenilin 1 and 2 control secretion of APP alpha and A beta by human cells and are degraded by proteasome
-
C. A. da Costa K. Ancolio F. Checler 1999 C-terminal maturation fragments of presenilin 1 and 2 control secretion of APP alpha and A beta by human cells and are degraded by proteasome Mol Med 5 160 168
-
(1999)
Mol Med
, vol.5
, pp. 160-168
-
-
Da Costa, C.A.1
Ancolio, K.2
Checler, F.3
-
5
-
-
0035072229
-
Degradation of oxidized proteins by the 20S proteasome
-
K. J. Davies 2001 Degradation of oxidized proteins by the 20S proteasome Biochimie 83 301 310.
-
(2001)
Biochimie
, vol.83
, pp. 301-310
-
-
Davies, K.J.1
-
6
-
-
33748283747
-
Accumulation of amyloid precursor protein in the mitochondrial import channels of human Alzheimer's disease brain is associated with mitochondrial dysfunction
-
L. Devi B. M. Prabhu D. F. Galati N. G. Avadhani H. K. Anandatheerthavarada 2006 Accumulation of amyloid precursor protein in the mitochondrial import channels of human Alzheimer's disease brain is associated with mitochondrial dysfunction J Neurosci 26 9057 9068
-
(2006)
J Neurosci
, vol.26
, pp. 9057-9068
-
-
Devi, L.1
Prabhu, B.M.2
Galati, D.F.3
Avadhani, N.G.4
Anandatheerthavarada, H.K.5
-
7
-
-
0035871971
-
Elevated vulnerability to oxidative stress-induced cell death and activation of caspase-3 by the Swedish amyloid precursor protein mutation
-
A. Eckert B. Steiner C. Marques S. Leutz H. Romig C. Haass W. E. Muller 2001 Elevated vulnerability to oxidative stress-induced cell death and activation of caspase-3 by the Swedish amyloid precursor protein mutation J Neurosci Res 64 183 192
-
(2001)
J Neurosci Res
, vol.64
, pp. 183-192
-
-
Eckert, A.1
Steiner, B.2
Marques, C.3
Leutz, S.4
Romig, H.5
Haass, C.6
Muller, W.E.7
-
8
-
-
0027076090
-
Normal processing of the Alzheimer's disease amyloid beta protein precursor generates potentially amyloidogenic carboxyl-terminal derivatives
-
S. Estus T. E. Golde S. G. Younkin 1992 Normal processing of the Alzheimer's disease amyloid beta protein precursor generates potentially amyloidogenic carboxyl-terminal derivatives Ann N Y Acad Sci 674 138 148
-
(1992)
Ann N y Acad Sci
, vol.674
, pp. 138-148
-
-
Estus, S.1
Golde, T.E.2
Younkin, S.G.3
-
9
-
-
0032841203
-
Antioxidant functions of sulforaphane: A potent inducer of Phase II detoxication enzymes
-
J. W. Fahey P. Talalay 1999 Antioxidant functions of sulforaphane: a potent inducer of Phase II detoxication enzymes Food Chem Toxicol 37 973 979
-
(1999)
Food Chem Toxicol
, vol.37
, pp. 973-979
-
-
Fahey, J.W.1
Talalay, P.2
-
10
-
-
0036083396
-
The ubiquitin-proteasome proteolytic pathway: Destruction for the sake of construction
-
M. H. Glickman A. Ciechanover 2002 The ubiquitin-proteasome proteolytic pathway: destruction for the sake of construction Physiol Rev 82 373 428.
-
(2002)
Physiol Rev
, vol.82
, pp. 373-428
-
-
Glickman, M.H.1
Ciechanover, A.2
-
12
-
-
0036268224
-
Hypothesis: Proteasomal dysfunction: A primary event in neurogeneration that leads to nitrative and oxidative stress and subsequent cell death
-
B. Halliwell 2002 Hypothesis: proteasomal dysfunction: a primary event in neurogeneration that leads to nitrative and oxidative stress and subsequent cell death Ann N Y Acad Sci 962 182 194.
-
(2002)
Ann N y Acad Sci
, vol.962
, pp. 182-194
-
-
Halliwell, B.1
-
13
-
-
0038155130
-
Proteasomal inhibition causes the formation of protein aggregates containing a wide range of proteins, including nitrated proteins
-
D. H. Hyun M. Lee B. Halliwell P. Jenner 2003 Proteasomal inhibition causes the formation of protein aggregates containing a wide range of proteins, including nitrated proteins J Neurochem 86 363 373.
-
(2003)
J Neurochem
, vol.86
, pp. 363-373
-
-
Hyun, D.H.1
Lee, M.2
Halliwell, B.3
Jenner, P.4
-
14
-
-
0027258525
-
The carboxy terminus of the beta amyloid protein is critical for the seeding of amyloid formation: Implications for the pathogenesis of Alzheimer's disease
-
J. T. Jarrett E. P. Berger P. T. Lansbury Jr. 1993 The carboxy terminus of the beta amyloid protein is critical for the seeding of amyloid formation: implications for the pathogenesis of Alzheimer's disease Biochemistry 32 4693 4697
-
(1993)
Biochemistry
, vol.32
, pp. 4693-4697
-
-
Jarrett, J.T.1
Berger, E.P.2
Lansbury Jr. P., T.3
-
15
-
-
0023105114
-
The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor
-
J. Kang H. G. Lemaire A. Unterbeck J. M. Salbaum C. L. Masters K. H. Grzeschik G. Multhaup K. Beyreuther B. Muller-Hill 1987 The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor Nature 325 733 736
-
(1987)
Nature
, vol.325
, pp. 733-736
-
-
Kang, J.1
Lemaire, H.G.2
Unterbeck, A.3
Salbaum, J.M.4
Masters, C.L.5
Grzeschik, K.H.6
Multhaup, G.7
Beyreuther, K.8
Muller-Hill, B.9
-
16
-
-
4344618623
-
Autophagy, proteasomes, lipofuscin, and oxidative stress in the aging brain
-
J. N. Keller E. Dimayuga Q. Chen J. Thorpe J. Gee Q. Ding 2004 Autophagy, proteasomes, lipofuscin, and oxidative stress in the aging brain Int J Biochem Cell Biol 36 2376 2391.
-
(2004)
Int J Biochem Cell Biol
, vol.36
, pp. 2376-2391
-
-
Keller, J.N.1
Dimayuga, E.2
Chen, Q.3
Thorpe, J.4
Gee, J.5
Ding, Q.6
-
17
-
-
33847050801
-
Cell Survival Responses to Environmental Stresses Via the Keap1-Nrf2-ARE Pathway
-
T. W. Kensler N. Wakabayashi S. Biswal 2007 Cell Survival Responses to Environmental Stresses Via the Keap1-Nrf2-ARE Pathway Annu Rev Pharmacol Toxicol 47 89 116
-
(2007)
Annu Rev Pharmacol Toxicol
, vol.47
, pp. 89-116
-
-
Kensler, T.W.1
Wakabayashi, N.2
Biswal, S.3
-
18
-
-
34547092719
-
Role of increased expression of the proteasome in the protective effects of sulforaphane against hydrogen peroxidemediated cytotoxicity in murine neuroblastoma cells
-
M. K. Kwak J. M. Cho B. Huang S. Shin T. W. Kensler 2007 Role of increased expression of the proteasome in the protective effects of sulforaphane against hydrogen peroxidemediated cytotoxicity in murine neuroblastoma cells Free Radic Biol Med 43 809 817
-
(2007)
Free Radic Biol Med
, vol.43
, pp. 809-817
-
-
Kwak, M.K.1
Cho, J.M.2
Huang, B.3
Shin, S.4
Kensler, T.W.5
-
19
-
-
34249727213
-
Tissue specific increase of the catalytic subunits of the 26S proteasome by indirect antioxidant dithiolethione in mice: Enhanced activity for degradation of abnormal protein
-
M. K. Kwak B. Huang H. Chang J. A. Kim T. W. Kensler 2007 Tissue specific increase of the catalytic subunits of the 26S proteasome by indirect antioxidant dithiolethione in mice: enhanced activity for degradation of abnormal protein Life Sci 80 2411 2420
-
(2007)
Life Sci
, vol.80
, pp. 2411-2420
-
-
Kwak, M.K.1
Huang, B.2
Chang, H.3
Kim, J.A.4
Kensler, T.W.5
-
20
-
-
0242721624
-
Antioxidants enhance mammalian proteasome expression through the Keap1-Nrf2 signaling pathway
-
M. K. Kwak N. Wakabayashi J. L. Greenlaw M. Yamamoto T. W. Kensler 2003 Antioxidants enhance mammalian proteasome expression through the Keap1-Nrf2 signaling pathway Mol Cell Biol 23 8786 8794.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 8786-8794
-
-
Kwak, M.K.1
Wakabayashi, N.2
Greenlaw, J.L.3
Yamamoto, M.4
Kensler, T.W.5
-
21
-
-
0037424262
-
Modulation of gene expression by cancer chemopreventive dithiolethiones through the Keap1-Nrf2 pathway. Identification of novel gene clusters for cell survival
-
M. K. Kwak N. Wakabayashi K. Itoh H. Motohashi M. Yamamoto T. W. Kensler 2003 Modulation of gene expression by cancer chemopreventive dithiolethiones through the Keap1-Nrf2 pathway. Identification of novel gene clusters for cell survival J Biol Chem 278 8135 8145
-
(2003)
J Biol Chem
, vol.278
, pp. 8135-8145
-
-
Kwak, M.K.1
Wakabayashi, N.2
Itoh, K.3
Motohashi, H.4
Yamamoto, M.5
Kensler, T.W.6
-
22
-
-
0028981717
-
The Alzheimer's A beta peptide induces neurodegeneration and apoptotic cell death in transgenic mice
-
F. M. LaFerla B. T. Tinkle C. J. Bieberich C. C. Haudenschild G. Jay 1995 The Alzheimer's A beta peptide induces neurodegeneration and apoptotic cell death in transgenic mice Nat Genet 9 21 30
-
(1995)
Nat Genet
, vol.9
, pp. 21-30
-
-
Laferla, F.M.1
Tinkle, B.T.2
Bieberich, C.J.3
Haudenschild, C.C.4
Jay, G.5
-
23
-
-
0034730172
-
Inhibition of the ubiquitin-proteasome system in Alzheimer's disease
-
Y. A. Lam C. M. Pickart A. Alban M. Landon C. Jamieson R. Ramage R. J. Mayer R. Layfield 2000 Inhibition of the ubiquitin-proteasome system in Alzheimer's disease Proc Natl Acad Sci U S A 97 9902 9906.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 9902-9906
-
-
Lam, Y.A.1
Pickart, C.M.2
Alban, A.3
Landon, M.4
Jamieson, C.5
Ramage, R.6
Mayer, R.J.7
Layfield, R.8
-
24
-
-
0030667097
-
Constitutive and protein kinase C-regulated secretory cleavage of Alzheimer's beta-amyloid precursor protein: Different control of early and late events by the proteasome
-
P. Marambaud E. Lopez-Perez S. Wilk F. Checler 1997 Constitutive and protein kinase C-regulated secretory cleavage of Alzheimer's beta-amyloid precursor protein: different control of early and late events by the proteasome J Neurochem 69 2500 2505
-
(1997)
J Neurochem
, vol.69
, pp. 2500-2505
-
-
Marambaud, P.1
Lopez-Perez, E.2
Wilk, S.3
Checler, F.4
-
26
-
-
0030779677
-
Cellular actions of beta-amyloid precursor protein and its soluble and fibrillogenic derivatives
-
M. P. Mattson 1997 Cellular actions of beta-amyloid precursor protein and its soluble and fibrillogenic derivatives Physiol Rev 77 1081 1132
-
(1997)
Physiol Rev
, vol.77
, pp. 1081-1132
-
-
Mattson, M.P.1
-
27
-
-
0032590054
-
Soluble pool of Abeta amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease
-
C. A. McLean R. A. Cherny F. W. Fraser S. J. Fuller M. J. Smith K. Beyreuther A. I. Bush C. L. Masters 1999 Soluble pool of Abeta amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease Ann Neurol 46 860 866
-
(1999)
Ann Neurol
, vol.46
, pp. 860-866
-
-
McLean, C.A.1
Cherny, R.A.2
Fraser, F.W.3
Fuller, S.J.4
Smith, M.J.5
Beyreuther, K.6
Bush, A.I.7
Masters, C.L.8
-
28
-
-
0034797234
-
The C-terminal fragment of the Alzheimer's disease amyloid protein precursor is degraded by a proteasome-dependent mechanism distinct from gamma-secretase
-
J. Nunan M. S. Shearman F. Checler R. Cappai G. Evin K. Beyreuther C. L. Masters D. H. Small 2001 The C-terminal fragment of the Alzheimer's disease amyloid protein precursor is degraded by a proteasome-dependent mechanism distinct from gamma-secretase Eur J Biochem 268 5329 5336
-
(2001)
Eur J Biochem
, vol.268
, pp. 5329-5336
-
-
Nunan, J.1
Shearman, M.S.2
Checler, F.3
Cappai, R.4
Evin, G.5
Beyreuther, K.6
Masters, C.L.7
Small, D.H.8
-
29
-
-
0242330370
-
Proteasome-mediated degradation of the C-terminus of the Alzheimer's disease beta-amyloid protein precursor: Effect of C-terminal truncation on production of beta-amyloid protein
-
J. Nunan N. A. Williamson A. F. Hill M. F. Sernee C. L. Masters D. H. Small 2003 Proteasome-mediated degradation of the C-terminus of the Alzheimer's disease beta-amyloid protein precursor: effect of C-terminal truncation on production of beta-amyloid protein J Neurosci Res 74 378 385
-
(2003)
J Neurosci Res
, vol.74
, pp. 378-385
-
-
Nunan, J.1
Williamson, N.A.2
Hill, A.F.3
Sernee, M.F.4
Masters, C.L.5
Small, D.H.6
-
30
-
-
33644639061
-
Proteasomal defense of oxidative protein modifications
-
D. Poppek T. Grune 2006 Proteasomal defense of oxidative protein modifications Antioxid Redox Signal 8 173 184
-
(2006)
Antioxid Redox Signal
, vol.8
, pp. 173-184
-
-
Poppek, D.1
Grune, T.2
-
31
-
-
0027459686
-
Secretion of beta-amyloid precursor protein cleaved at the amino terminus of the beta-amyloid peptide
-
P. Seubert T. Oltersdorf M. G. Lee R. Barbour C. Blomquist D. L. Davis K. Bryant L. C. Fritz D. Galasko L. J. Thal 1993 Secretion of beta-amyloid precursor protein cleaved at the amino terminus of the beta-amyloid peptide Nature 361 260 263
-
(1993)
Nature
, vol.361
, pp. 260-263
-
-
Seubert, P.1
Oltersdorf, T.2
Lee, M.G.3
Barbour, R.4
Blomquist, C.5
Davis, D.L.6
Bryant, K.7
Fritz, L.C.8
Galasko, D.9
Thal, L.J.10
-
32
-
-
0037411555
-
Neurodegenerative disorders of protein aggregation
-
B. S. Shastry 2003 Neurodegenerative disorders of protein aggregation Neurochem Int 43 1 7
-
(2003)
Neurochem Int
, vol.43
, pp. 1-7
-
-
Shastry, B.S.1
-
33
-
-
34249653138
-
Protein aggregation and aggregate toxicity: New insights into protein folding, misfolding diseases and biological evolution
-
M. Stefani C. M. Dobson 2003 Protein aggregation and aggregate toxicity: new insights into protein folding, misfolding diseases and biological evolution J Mol Med 27 27
-
(2003)
J Mol Med
, vol.27
, pp. 27
-
-
Stefani, M.1
Dobson, C.M.2
-
34
-
-
0032867676
-
The 26S proteasome: A molecular machine designed for controlled proteolysis
-
D. Voges P. Zwickl W. Baumeister 1999 The 26S proteasome: a molecular machine designed for controlled proteolysis Annu Rev Biochem. 68 1015 1068.
-
(1999)
Annu Rev Biochem.
, vol.68
, pp. 1015-1068
-
-
Voges, D.1
Zwickl, P.2
Baumeister, W.3
|