(RS)-glucoraphanin purified from Tuscan black kale and bioactivated with myrosinase enzyme protects against cerebral ischemia/reperfusion injury in rats

Fitoterapia

Volumn 99, Issue , 2014, Pages 166-177

  Giacoppo, Sabrina ^a   Galuppo, Maria ^a   Iori, Renato ^b   De Nicola, Gina Rosalinda ^b   Bramanti, Placido ^a   Mazzon, Emanuela ^a  

^a IRCCS CENTRO NEUROLESI BONINO PULEJO   (Italy)

^b ISTITUTO NAZIONALE DELLA NUTRIZIONE   (Italy)

Author keywords

Apoptosis; Bioactive (RS) glucoraphanin; Cerebral ischemia reperfusion; Inflammation; Oxidative stress

Indexed keywords

CASPASE 3; GLUCORAPHANIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERCELLULAR ADHESION MOLECULE 1; NEUROPROTECTIVE AGENT; PLANT MEDICINAL PRODUCT; THIOGLUCOSIDASE; UNCLASSIFIED DRUG; CASP3 PROTEIN, RAT; GLUCOSINOLATE; GLYCOSIDASE; I KAPPA B; IMIDOESTER; NF-KAPPAB INHIBITOR ALPHA; NOS2 PROTEIN, RAT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN ISCHEMIA; BRASSICA OLERACEA; BRASSICACEAE; CAROTID ARTERY OBSTRUCTION; CONTROLLED STUDY; DRUG INHIBITION; DRUG STRUCTURE; GENE EXPRESSION; GENE TRANSLOCATION; IMMUNOHISTOCHEMISTRY; KALE; MALE; NEUROPROTECTION; NICK END LABELING; NONHUMAN; RAT; REPERFUSION INJURY; TUSCAN BLACK KALE; ANIMAL; BRASSICA; CHEMISTRY; DRUG EFFECTS; METABOLISM; WISTAR RAT;

ANIMALS; APOPTOSIS; BRAIN ISCHEMIA; BRASSICA; CASPASE 3; GLUCOSINOLATES; GLYCOSIDE HYDROLASES; I-KAPPA B PROTEINS; IMIDOESTERS; INTERCELLULAR ADHESION MOLECULE-1; MALE; NEUROPROTECTIVE AGENTS; NF-KAPPA B; NITRIC OXIDE SYNTHASE TYPE II; RATS, WISTAR; REPERFUSION INJURY;

EID: 84908030091     PISSN: 0367326X     EISSN: 18736971     Source Type: Journal    
DOI: 10.1016/j.fitote.2014.09.016     Document Type: Article

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