Protective role of (RS)-glucoraphanin bioactivated with myrosinase in an experimental model of multiple sclerosis

CNS Neuroscience and Therapeutics

Volumn 19, Issue 8, 2013, Pages 577-584

  Giacoppo, Sabrina ^a   Galuppo, Maria ^a   Iori, Renato ^b   De Nicola, Gina R ^b   Cassata, Giovanni ^c   Bramanti, Placido ^a   Mazzon, Emanuela ^a  

^a IRCCS CENTRO NEUROLESI BONINO PULEJO   (Italy)

^b ISTITUTO NAZIONALE DELLA NUTRIZIONE   (Italy)

^c ISTITUTO ZOOPROFILATTICO SPERIMENTALE DELLA SICILIA A MIRRI   (Italy)

Author keywords

Apoptosis; Bioactive (RS) glucoraphanin; Experimental autoimmune encephalomyelitis; Inflammation; Multiple sclerosis

Indexed keywords

CASPASE 3; GLUCORAPHANIN; HERBACEOUS AGENT; I KAPPA B ALPHA; INTERLEUKIN 1BETA; MYELIN OLIGODENDROCYTE GLYCOPROTEIN; NEUROPROTECTIVE AGENT; PROTEIN BAX; STRESS ACTIVATED PROTEIN KINASE; THIOGLUCOSIDASE; TRANSCRIPTION FACTOR RELA; UNCLASSIFIED DRUG; GLUCOSINOLATE; GLYCOSIDASE; IMIDOESTER; PLANT EXTRACT;

ALLERGIC ENCEPHALOMYELITIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; ASTROCYTE; BIOLOGICAL ACTIVITY; BODY WEIGHT; BRASSICA OLERACEA; CELL DEATH; CONTROLLED STUDY; CYTOKINE PRODUCTION; DYING; ENZYME ACTIVITY; MALE; MOUSE; MULTIPLE SCLEROSIS; MUSCLE HYPOTONIA; NEUROPROTECTION; NONHUMAN; PARALYSIS; PROTEIN DEGRADATION; PROTEIN EXPRESSION; SCORING SYSTEM; SPINAL CORD; WEIGHT GAIN; WEIGHT REDUCTION; WESTERN BLOTTING; AMINO ACID SEQUENCE; ANIMAL; BIOACTIVE (RS)-GLUCORAPHANIN; BRASSICA; C57BL MOUSE; DISEASE MODEL; EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS; GENETICS; INFLAMMATION; ISOLATION AND PURIFICATION; MOLECULAR GENETICS; PATHOLOGY; RANDOMIZATION;

APOPTOSIS; BIOACTIVE (RS)-GLUCORAPHANIN; EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS; INFLAMMATION; MULTIPLE SCLEROSIS;

AMINO ACID SEQUENCE; ANIMALS; BRASSICA; DISEASE MODELS, ANIMAL; GLUCOSINOLATES; GLYCOSIDE HYDROLASES; IMIDOESTERS; MALE; MICE; MICE, INBRED C57BL; MOLECULAR SEQUENCE DATA; MULTIPLE SCLEROSIS; NEUROPROTECTIVE AGENTS; PLANT EXTRACTS; RANDOM ALLOCATION;

EID: 84880698963     PISSN: 17555930     EISSN: 17555949     Source Type: Journal    
DOI: 10.1111/cns.12106     Document Type: Article

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