Sulforaphane attenuates matrix metalloproteinase-9 expression following spinal cord injury in mice

Annals of Clinical and Laboratory Science

Volumn 40, Issue 4, 2010, Pages 354-360

  Mao, Lei ^a   Wang, Han Dong ^a   Wang, Xiao Liang ^a   Qiao, Liang ^a   Yin, Hong Xia ^a  

^a NANJING UNIVERSITY   (China)

Author keywords

Matrix metalloproteinase 9; Spinal cord injury; Sulforaphane; TNF

Indexed keywords

GELATINASE B; MESSENGER RNA; SULFORAPHANE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVITY; LAMINECTOMY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SPINAL CORD; SPINAL CORD INJURY; WATER CONTENT; ZYMOGRAPHY;

ANIMALS; CAPILLARY PERMEABILITY; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION REGULATION, ENZYMOLOGIC; MALE; MATRIX METALLOPROTEINASE 9; MICE; MICE, INBRED ICR; ORGAN SIZE; RNA, MESSENGER; SPINAL CORD; SPINAL CORD INJURIES; THIOCYANATES; TUMOR NECROSIS FACTOR-ALPHA;

MURINAE; MUS;

EID: 77958071059     PISSN: 00917370     EISSN: 15508080     Source Type: Journal    
DOI: None     Document Type: Article

References (42)

1. Choo AM, Liu J, Dvorak M, Tetzlaff W, Oxland TR. Secondary pathology following contusion, dislocation, and distraction spinal cord injuries. Exp Neurol 2008; 212:490-506.
2. Kwon BK, Tetzlaff W, Grauer JN, Beiner J, Vaccaro AR. Pathophysiology and pharmacologic treatment of acute spinal cord injury. Spine J 2004;4:451-464. (Pubitemid 38992289)
3. Hausmann ON. Post-traumatic inflammation following spinal cord injury. Spinal Cord 2003;41:369-378.
4. Donnelly DJ, Popovich PG. Inflammation and its role in neuroprotection, axonal regeneration and functional recovery after spinal cord injury. Exp Neurol 2008;209: 378-388.
5. Trivedi A, Olivas AD, Noble-Haeusslein LJ. Inflammation and spinal cord injury: infiltrating leukocytes as determinants of injury and repair processes. Clin Neurosci Res 2006;6:283-292. (Pubitemid 44849178)
6. Chavarria A, Alcocer-Varela J. Is damage in central nervous system due to inflammation? Autoimmun Rev 2004;3:251-260.
7. Noble LJ, Donovan F, Igarashi T, Goussev S, Werb Z. Matrix metalloproteinases limit functional recovery after spinal cord injury by modulation of early vascular events. J Neurosci 2002;22:7526-7535.
8. Birkedal-Hansen H, Moore WG, Bodden MK, Windsor LJ, Birkedal-Hansen B, DeCarlo A, Engler JA. Matrix metalloproteinases: a review. Crit Rev Oral Biol Med 1993;4:197-250.
9. Castaneda FE, Walia B, Vijay-Kumar M, Patel NR, Roser S, Kolachala VL, Rojas M, Wang L, Oprea G, Garg P, Gewirtz AT, Roman J, Merlin D, Sitaraman SV. Targeted deletion of metalloproteinase 9 attenuates experimental colitis in mice: central role of epithelial-derived MMP. Gastroenterology 2005;129:1991-2008.
10. Mott JD, Werb Z. Regulation of matrix biology by matrix metalloproteinases. Curr Opin Cell Biol 2004;16: 558-564.
11. Yu F, Kamada H, Niizuma K, Endo H, Chan PH. Induction of MMP-9 expression and endothelial injury by oxidative stress after spinal cord injury. J Neurotrauma 2008;25:184-195.
12. Esposito E, Genovese T, Caminiti R, Bramanti P, Meli R, Cuzzocrea S. Melatonin regulates matrix metalloproteinases after traumatic experimental spinal cord injury. J Pineal Res 2008;45:149-156.
13. de Castro R, Burns CL, McAdoo DJ, Romanic AM. Metalloproteinase increases in the injured rat spinal cord. Neuroreport 2000;11:3551-3554.
14. Mautes AE, Weinzierl MR, Donovan F, Noble LJ. Vascular events after spinal cord injury: contribution to secondary pathogenesis. Phys Ther 2000;80:673-687.
15. Buss A, Pech K, Kakulas BA, Martin D, Schoenen J, Noth J, Brook GA. Matrix metalloproteinases and their inhibitors in human traumatic spinal cord injury. BMC Neurol 2007;7:17.
16. Heiss E, Herhaus C, Klimo K, Bartsch H, Gerhauser C. Nuclear factor kappa B is a molecular target for sulforaphane- mediated anti-inflammatory mechanisms. J Biol Chem 2001;276:32008-32015.
17. Rose P, Huang Q, Ong CN, Whiteman M. Broccoli and watercress suppress matrix metalloproteinase-9 activity and invasiveness of human MDA-MB-231 breast cancer cells. Toxicol Appl Pharmacol 2005;209:105-113.
18. Choi WY, Choi BT, Lee WH, Choi YH. Sulforaphane generates reactive oxygen species leading to mitochondrial perturbation for apoptosis in human leukemia U937 cells. Biomed Pharmacother 2008;62:637-644.
19. Annabi B, Rojas-Sutterlin S, Laroche M, Lachambre MP, Moumdjian R, Beliveau R. The diet-derived sulforaphane inhibits matrix metalloproteinase-9- activated human brain microvascular endothelial cell migration and tubulogenesis. Mol Nutr Food Res 2008;52:692-700.
20. Marques SA, Garcez VF, Del Bel EA, Martinez AM. A simple, inexpensive and easily reproducible model of spinal cord injury in mice: morphological and functional assessment. J Neurosci Methods 2009;177:183-193.
21. Joshi M, Fehlings MG. Development and characterization of a novel, graded model of clip compressive spinal cord injury in the mouse: Clip design, behavioral outcomes, and histopathology. J Neurotrauma 2002; 19:175-190. (Pubitemid 34184609)
22. von Euler M, Seiger A, Sundstrom E. Clip compression injury in the spinal cord: a correlative study of neurological and morphological alterations. Exp Neurol 1997; 145:502-510.
23. Basso DM, Fisher LC, Anderson AJ, Jakeman LB, McTigue DM, Popovich PG. Basso mouse scale for locomotion detects differences in recovery after spinal cord injury in five common mouse strains. J Neurotrauma 2006;23:635-659.
24. Zhao J, Moore AN, Clifton GL, Dash PK. Sulforaphane enhances aquaporin-4 expression and decreases cerebral edema following traumatic brain injury. J Neurosci Res 2005;82:499-506.
25. Tanito M, Masutani H, Kim YC, Nishikawa M, Ohira A, Yodoi J. Sulforaphane induces thioredoxin through antioxidant-responsive element and attenuates retinal light damage in mice. Invest Ophthalmol Vis Sci 2005; 46:979-987.
26. Zhao X, Sun G, Zhang J, Strong R, Dash PK, Kan YW, Grotta JC, Aronowski J. Transcription factor Nrf2 protects the brain from damage produced by intracerebral hemorrhage. Stroke 2007;38:3280-3286.
27. Saadoun S, Bell BA, Verkman AS, Papadopoulos MC. Greatly improved neurological outcome after spinal cord compression injury in AQP4-deficient mice. Brain 2008; 131:1087-1098.
28. Cheung C, Luo H, Yanagawa B, Leong HS, Samarasekera D, Lai JC, Suarez A, Zhang J, McManus BM. Matrix metalloproteinases and tissue inhibitors of metalloproteinases in Coxsackie virus-induced myocarditis. Cardiovasc Pathol 2006;15:63-74.
29. Jin W, Wang H, Yan W, Zhu L, Hu Z, Ding Y, Tang K. Role of Nrf2 in protection against traumatic brain injury in mice. J Neurotrauma 2009;26:131-139.
30. Herron GS, Banda MJ, Clark EJ, Gavrilovic J, Werb Z. Secretion of metalloproteinases by stimulated capillary endothelial cells. II. Expression of collagenase and stromelysin activities is regulated by endogenous inhibitors. J Biol Chem 1986;261:2814-2818.
31. Beattie MS, Li Q, Bresnahan JC. Cell death and plasticity after experimental spinal cord injury. Prog Brain Res 2000;128:9-21.
32. Xu J, Fan G, Chen S, Wu Y, Xu XM, Hsu CY. Methylprednisolone inhibition of TNF-alpha expression and NF-κB activation after spinal cord injury in rats. Brain Res Mol Brain Res 1998;59:135-142.
33. Nakamura M, Houghtling RA, MacArthur L, Bayer BM, Bregman BS. Differences in cytokine gene expression profile between acute and secondary injury in adult rat spinal cord. Exp Neurol 2003;184:313-325. (Pubitemid 37444041)
34. Lempinen M, Inkinen K, Wolff H, Ahonen J. Matrix metalloproteinases 2 and 9 in indomethacin-induced rat gastric ulcer. Eur Surg Res 2000;32:169-176.
35. Mori N, Sato H, Hayashibara T, Senba M, Geleziunas R, Wada A, Hirayama T, Yamamoto N. Helicobacter pylori induces matrix metalloproteinase-9 through activation of nuclear factor kappaB. Gastroenterology 2003; 124:983-992.
36. Surh YJ, Na HK. NF-kappaB and Nrf2 as prime molecular targets for chemoprevention and cytoprotection with anti-inflammatory and antioxidant phytochemicals. Genes Nutr 2008;2:313-317.
37. Juge N, Mithen RF, Traka M. Molecular basis for chemoprevention by sulforaphane: a comprehensive review. Cell Mol Life Sci 2007;64:1105-1127.
38. Thimmulappa RK, Mai KH, Srisuma S, Kensler TW, Yamamoto M, Biswal S. Identification of Nrf2-regulated genes induced by the chemopreventive agent sulforaphane by oligonucleotide microarray. Cancer Res 2002; 62:5196-5203.
39. Brandenburg LO, Kipp M, Lucius R, Pufe T, Wruck CJ. Sulforaphane suppresses LPS-induced inflammation in primary rat microglia. Inflamm Res 2010;59:443-450.
40. Moon DO, Kim MO, Kang SH, Choi YH, Kim GY. Sulforaphane suppresses TNF-alpha-mediated activation of NF-kappaB and induces apoptosis through activation of reactive oxygen species-dependent caspase-3. Cancer Lett 2009;274:132-142.
41. Kwon BK, Okon E, Hillyer J, Mann C, Baptiste D, Weaver LC, Fehlings MG, Tetzlaff W. A systematic review of non-invasive pharmacologic neuroprotective treatments for acute spinal cord injury. J Neurotrauma 2010;Apr 14, [Epub ahead of print].
42. Bottai D, Cigognini D, Madaschi L, Adami R, Nicora E, Menarini M, Di Giulio AM, Gorio A. Embryonic stem cells promote motor recovery and affect inflammatory cell infiltration in spinal cord injured mice. Exp Neurol 2010;223:452-463.