Synthesis and Nrf2-inducing activity of the isothiocyanates iberverin, iberin and cheirolin

Pharmacological Research

Volumn 70, Issue 1, 2013, Pages 155-162

  Ernst, Insa M A ^a   Palani, Kalpana ^a   Esatbeyoglu, Tuba ^a   Schwarz, Karin ^a   Rimbach, Gerald ^a  

^a UNIVERSITY OF KIEL   (Germany)

Author keywords

Cheirolin; Chemical isothiocyanate synthesis; Iberin; Iberverin; Nrf2

Indexed keywords

CHEIROLIN; GLUTAMATE CYSTEINE LIGASE; HEME OXYGENASE 1; IBERIN; IBERVERIN; ISOTHIOCYANIC ACID DERIVATIVE; KELCH LIKE ECH ASSOCIATED PROTEIN 1; MESSENGER RNA; SULFORAPHANE; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG;

ARTICLE; CELL LEVEL; CHEMICAL STRUCTURE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; FIBROBLAST; GENE EXPRESSION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; ISOLATION AND PURIFICATION; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTON NUCLEAR MAGNETIC RESONANCE; SIGNAL TRANSDUCTION; SYNTHESIS;

ACTIVE TRANSPORT, CELL NUCLEUS; ANIMALS; BLOTTING, WESTERN; CELL CULTURE TECHNIQUES; CELL NUCLEUS; CELL SURVIVAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; ISOTHIOCYANATES; MICE; MOLECULAR STRUCTURE; NF-E2-RELATED FACTOR 2; NIH 3T3 CELLS; REAL-TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; STRUCTURE-ACTIVITY RELATIONSHIP; SULFIDES; SULFONES;

EID: 84875157012     PISSN: 10436618     EISSN: 10961186     Source Type: Journal    
DOI: 10.1016/j.phrs.2013.01.011     Document Type: Article

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