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Volumn 38, Issue , 2015, Pages 127-149

Glutamate Synapses in Human Cognitive Disorders

Author keywords

Autism; Excitatory; Intellectual disability; Neurodevelopmental; Plasticity; Schizophrenia

Indexed keywords

ARTICLE; AUTISM; CELL ADHESION; COGNITION; COGNITIVE DEFECT; DENDRITIC SPINE; EXECUTIVE FUNCTION; GENETIC ASSOCIATION; GENETIC SUSCEPTIBILITY; GLUTAMATERGIC SYNAPSE; HUMAN; INTELLECTUAL IMPAIRMENT; INTELLIGENCE; INTERPERSONAL COMMUNICATION; LONG TERM POTENTIATION; NERVE CELL PLASTICITY; NEUROTRANSMISSION; NONHUMAN; PERCEPTION; PRIORITY JOURNAL; PROTEIN FUNCTION; REGULATORY MECHANISM; RETT SYNDROME; SCHIZOPHRENIA; SIGNAL TRANSDUCTION; SOCIAL INTERACTION; SYNAPTIC TRANSMISSION; ANIMAL; BIOLOGICAL MODEL; GENETIC PREDISPOSITION; GENETICS; PATHOPHYSIOLOGY; PHYSIOLOGY; SYNAPSE;

EID: 84937409911     PISSN: 0147006X     EISSN: 15454126     Source Type: Book Series    
DOI: 10.1146/annurev-neuro-071714-033821     Document Type: Article
Times cited : (186)

References (169)
  • 1
    • 84897088758 scopus 로고    scopus 로고
    • CYFIP family proteins between autism and intellectual disability: Links with Fragile X syndrome
    • Abekhoukh S, Bardoni B. 2014. CYFIP family proteins between autism and intellectual disability: links with Fragile X syndrome. Front. Cell. Neurosci. 8:81
    • (2014) Front. Cell. Neurosci. , vol.8 , pp. 81
    • Abekhoukh, S.1    Bardoni, B.2
  • 2
    • 0032830639 scopus 로고    scopus 로고
    • Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2
    • Amir RE, Van den Veyver IB, Wan M, Tran CQ, Francke U, Zoghbi HY. 1999. Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2. Nat. Genet. 23:185-88
    • (1999) Nat. Genet. , vol.23 , pp. 185-188
    • Amir, R.E.1    Van Den Veyver, I.B.2    Wan, M.3    Tran, C.Q.4    Francke, U.5    Zoghbi, H.Y.6
  • 3
    • 84879970825 scopus 로고    scopus 로고
    • Presynaptic neurexin-3 alternative splicing trans-synaptically controls postsynaptic AMPA receptor trafficking
    • Aoto J, Martinelli DC, Malenka RC, Tabuchi K, Sudhof TC. 2013. Presynaptic neurexin-3 alternative splicing trans-synaptically controls postsynaptic AMPA receptor trafficking. Cell 154:75-88
    • (2013) Cell , vol.154 , pp. 75-88
    • Aoto, J.1    Martinelli, D.C.2    Malenka, R.C.3    Tabuchi, K.4    Sudhof, T.C.5
  • 4
    • 84920715741 scopus 로고    scopus 로고
    • Rapid dispersion of SynGAP from synaptic spines triggers AMPA receptor insertion and spine enlargement during LTP
    • Araki Y, Zeng M, Zhang M, Huganir RL. 2015. Rapid dispersion of SynGAP from synaptic spines triggers AMPA receptor insertion and spine enlargement during LTP. Neuron 85:173-89
    • (2015) Neuron , vol.85 , pp. 173-189
    • Araki, Y.1    Zeng, M.2    Zhang, M.3    Huganir, R.L.4
  • 5
    • 77955950918 scopus 로고    scopus 로고
    • Loss of the fragile X mental retardation protein decouples metabotropic glutamate receptor dependent priming of long-term potentiation from protein synthesis
    • Auerbach BD, Bear MF. 2010. Loss of the fragile X mental retardation protein decouples metabotropic glutamate receptor dependent priming of long-term potentiation from protein synthesis. J. Neurophysiol. 104:1047-51
    • (2010) J. Neurophysiol. , vol.104 , pp. 1047-1051
    • Auerbach, B.D.1    Bear, M.F.2
  • 6
    • 79960057257 scopus 로고    scopus 로고
    • NMDA receptor blockade at rest triggers rapid behavioural antidepressant responses
    • Autry AE, Adachi M, Nosyreva E, Na ES, Los MF, et al. 2011. NMDA receptor blockade at rest triggers rapid behavioural antidepressant responses. Nature 475:91-95
    • (2011) Nature , vol.475 , pp. 91-95
    • Autry, A.E.1    Adachi, M.2    Nosyreva, E.3    Na, E.S.4    Los, M.F.5
  • 7
    • 84883221005 scopus 로고    scopus 로고
    • RhoGTPase signaling at the synapse: Implications for intellectual disability
    • Ba W, van der Raadt J, Nadif KasriN. 2013. RhoGTPase signaling at the synapse: implications for intellectual disability. Exp. Cell Res. 319:2368-74
    • (2013) Exp. Cell Res. , vol.319 , pp. 2368-2374
    • Ba, W.1    Van Der Raadt, J.2    Nadif Kasri, N.3
  • 8
    • 84879518895 scopus 로고    scopus 로고
    • Multiple risk pathways for schizophrenia converge in serine racemase knockout mice, a mouse model of NMDA receptor hypofunction
    • Balu DT, Li Y, Puhl MD, Benneyworth MA, Basu AC, et al. 2013. Multiple risk pathways for schizophrenia converge in serine racemase knockout mice, a mouse model of NMDA receptor hypofunction. PNAS 110:E2400-9
    • (2013) PNAS , vol.110 , pp. E2400-E2409
    • Balu, D.T.1    Li, Y.2    Puhl, M.D.3    Benneyworth, M.A.4    Basu, A.C.5
  • 9
  • 10
    • 73949136265 scopus 로고    scopus 로고
    • PostnatalNMDAreceptor ablation in corticolimbic interneurons confers schizophrenia-like phenotypes
    • Belforte JE, Zsiros V, Sklar ER, Jiang Z, YuG, et al. 2010. PostnatalNMDAreceptor ablation in corticolimbic interneurons confers schizophrenia-like phenotypes. Nat. Neurosci. 13:76-83
    • (2010) Nat. Neurosci. , vol.13 , pp. 76-83
    • Belforte, J.E.1    Zsiros, V.2    Sklar, E.R.3    Jiang, Z.4    Yu, G.5
  • 11
    • 0027963287 scopus 로고
    • Rett syndrome: 3-D confocal microscopy of cortical pyramidal dendrites and afferents
    • Belichenko PV, Oldfors A, Hagberg B, Dahlstrom A. 1994. Rett syndrome: 3-D confocal microscopy of cortical pyramidal dendrites and afferents. NeuroReport 5:1509-13
    • (1994) NeuroReport , vol.5 , pp. 1509-1513
    • Belichenko, P.V.1    Oldfors, A.2    Hagberg, B.3    Dahlstrom, A.4
  • 12
    • 33750445959 scopus 로고    scopus 로고
    • Lamina-specific abnormalities of AMPA receptor trafficking and signaling molecule transcripts in the prefrontal cortex in schizophrenia
    • Beneyto M, Meador-Woodruff JH. 2006. Lamina-specific abnormalities of AMPA receptor trafficking and signaling molecule transcripts in the prefrontal cortex in schizophrenia. Synapse 60:585-98
    • (2006) Synapse , vol.60 , pp. 585-598
    • Beneyto, M.1    Meador-Woodruff, J.H.2
  • 13
    • 79952313620 scopus 로고    scopus 로고
    • Etiological heterogeneity in autism spectrum disorders:more than 100 genetic and genomic disorders and still counting
    • Betancur C. 2011. Etiological heterogeneity in autism spectrum disorders:more than 100 genetic and genomic disorders and still counting. Brain Res. 1380:42-77
    • (2011) Brain Res. , vol.1380 , pp. 42-77
    • Betancur, C.1
  • 14
    • 84862637069 scopus 로고    scopus 로고
    • The pathophysiology of fragileX(and what it teaches us about synapses)
    • Bhakar AL, Dölen G, Bear MF. 2012. The pathophysiology of fragileX(and what it teaches us about synapses). Annu. Rev. Neurosci. 35:417-43
    • (2012) Annu. Rev. Neurosci. , vol.35 , pp. 417-443
    • Bhakar, A.L.1    Dölen, G.2    Bear, M.F.3
  • 15
    • 57649228990 scopus 로고    scopus 로고
    • Cognitive impairment in Gdi1-deficient mice is associated with altered synaptic vesicle pools and short-term synaptic plasticity, and can be corrected by appropriate learning training
    • Bianchi V, Farisello P, Baldelli P, Meskenaite V, Milanese M, et al. 2009. Cognitive impairment in Gdi1-deficient mice is associated with altered synaptic vesicle pools and short-term synaptic plasticity, and can be corrected by appropriate learning training. Hum. Mol. Genet. 18:105-17
    • (2009) Hum. Mol. Genet. , vol.18 , pp. 105-117
    • Bianchi, V.1    Farisello, P.2    Baldelli, P.3    Meskenaite, V.4    Milanese, M.5
  • 16
    • 0032580161 scopus 로고    scopus 로고
    • Oligophrenin-1 encodes a rhoGAP protein involved in X-linked mental retardation
    • Billuart P, Bienvenu T, Ronce N, des Portes V, Vinet MC, et al. 1998. Oligophrenin-1 encodes a rhoGAP protein involved in X-linked mental retardation. Nature 392:923-26
    • (1998) Nature , vol.392 , pp. 923-926
    • Billuart, P.1    Bienvenu, T.2    Ronce, N.3    Des Portes, V.4    Vinet, M.C.5
  • 17
    • 79955884485 scopus 로고    scopus 로고
    • Modelling schizophrenia using human induced pluripotent stem cells
    • Brennand KJ, Simone A, Jou J, Gelboin-Burkhart C, Tran N, et al. 2011. Modelling schizophrenia using human induced pluripotent stem cells. Nature 473:221-25
    • (2011) Nature , vol.473 , pp. 221-225
    • Brennand, K.J.1    Simone, A.2    Jou, J.3    Gelboin-Burkhart, C.4    Tran, N.5
  • 18
    • 0347419233 scopus 로고    scopus 로고
    • Disruption of prepulse inhibition in mice lacking mGluR1
    • Brody SA, Conquet F, Geyer MA. 2003. Disruption of prepulse inhibition in mice lacking mGluR1. Eur. J. Neurosci. 18:3361-66
    • (2003) Eur. J. Neurosci. , vol.18 , pp. 3361-3366
    • Brody, S.A.1    Conquet, F.2    Geyer, M.A.3
  • 19
    • 84887090057 scopus 로고    scopus 로고
    • Rare variants analysis of neurexin-1in autism reveals a novel start codon mutation affecting protein levels at synapses
    • Camacho-Garcia RJ, Hervás A, Toma C, Balmaña N, Cormand B, et al. 2013. Rare variants analysis of neurexin-1in autism reveals a novel start codon mutation affecting protein levels at synapses. Psychiatr. Genet. 23:262-66
    • (2013) Psychiatr. Genet. , vol.23 , pp. 262-266
    • Camacho-Garcia, R.J.1    Hervás, A.2    Toma, C.3    Balmaña, N.4    Cormand, B.5
  • 20
    • 58149379613 scopus 로고    scopus 로고
    • SynGAP regulates steady-state and activitydependent phosphorylation of cofilin
    • Carlisle HJ, Manzerra P, Marcora E, Kennedy MB. 2008. SynGAP regulates steady-state and activitydependent phosphorylation of cofilin. J. Neurosci. 28:13673-83
    • (2008) J. Neurosci. , vol.28 , pp. 13673-13683
    • Carlisle, H.J.1    Manzerra, P.2    Marcora, E.3    Kennedy, M.B.4
  • 21
    • 84862628165 scopus 로고    scopus 로고
    • Structural plasticity upon learning: Regulation and functions
    • Caroni P, Donato F, Muller D. 2012. Structural plasticity upon learning: Regulation and functions. Nat. Rev. Neurosci. 13:478-90
    • (2012) Nat. Rev. Neurosci. , vol.13 , pp. 478-490
    • Caroni, P.1    Donato, F.2    Muller, D.3
  • 22
    • 0033869715 scopus 로고    scopus 로고
    • Endocytic pathway abnormalities precede amyloid deposition in sporadic Alzheimer's disease and Down syndrome: Differential effects of APOE genotype and presenilin mutations
    • Cataldo AM, Peterhoff CM, Troncoso JC, Gomez-Isla T, Hyman BT, Nixon RA. 2000. Endocytic pathway abnormalities precede amyloid deposition in sporadic Alzheimer's disease and Down syndrome: differential effects of APOE genotype and presenilin mutations. Am. J. Pathol. 157:277-86
    • (2000) Am. J. Pathol. , vol.157 , pp. 277-286
    • Cataldo, A.M.1    Peterhoff, C.M.2    Troncoso, J.C.3    Gomez-Isla, T.4    Hyman, B.T.5    Nixon, R.A.6
  • 23
    • 84898957499 scopus 로고    scopus 로고
    • Prevalence of autism spectrum disorder among children aged 8 years-Autism andDevelopmentalDisabilitiesMonitoringNetwork, 11 sites, United States, 2010
    • CDC (Cent. Dis. Control Prev.)
    • CDC (Cent. Dis. Control Prev.). 2014. Prevalence of autism spectrum disorder among children aged 8 years-Autism andDevelopmentalDisabilitiesMonitoringNetwork, 11 sites, United States, 2010. Morb. Mortal. Wkly. Rep. 63:1-21
    • (2014) Morb. Mortal. Wkly. Rep. , vol.63 , pp. 1-21
  • 24
    • 84888876863 scopus 로고    scopus 로고
    • Meeting at the crossroads: Common mechanisms in Fragile X and Down syndrome
    • Chang KT, Ro H, Wang W, Min KT. 2013. Meeting at the crossroads: common mechanisms in Fragile X and Down syndrome. Trends Neurosci. 36:685-94
    • (2013) Trends Neurosci. , vol.36 , pp. 685-694
    • Chang, K.T.1    Ro, H.2    Wang, W.3    Min, K.T.4
  • 25
    • 33748895740 scopus 로고    scopus 로고
    • Neurocognitive profile in 22q11 deletion syndrome and schizophrenia
    • Chow EW, WatsonM, Young DA, Bassett AS. 2006. Neurocognitive profile in 22q11 deletion syndrome and schizophrenia. Schizophr. Res. 87:270-78
    • (2006) Schizophr. Res. , vol.87 , pp. 270-278
    • Chow, E.W.1    Watson, M.2    Young, D.A.3    Bassett, A.S.4
  • 27
    • 84869038551 scopus 로고    scopus 로고
    • Pathogenic SYNGAP1 mutations impair cognitive development by disrupting maturation of dendritic spine synapses
    • Clement JP, Aceti M, Creson TK, Ozkan ED, Shi Y, et al. 2012. Pathogenic SYNGAP1 mutations impair cognitive development by disrupting maturation of dendritic spine synapses. Cell 151:709-23
    • (2012) Cell , vol.151 , pp. 709-723
    • Clement, J.P.1    Aceti, M.2    Creson, T.K.3    Ozkan, E.D.4    Shi, Y.5
  • 28
    • 84879152374 scopus 로고    scopus 로고
    • SYNGAP1 links the maturation rate of excitatory synapses to the duration of critical-period synaptic plasticity
    • Clement JP, Ozkan ED, Aceti M, Miller CA, Rumbaugh G. 2013. SYNGAP1 links the maturation rate of excitatory synapses to the duration of critical-period synaptic plasticity. J. Neurosci. 33:10447-52
    • (2013) J. Neurosci. , vol.33 , pp. 10447-10452
    • Clement, J.P.1    Ozkan, E.D.2    Aceti, M.3    Miller, C.A.4    Rumbaugh, G.5
  • 29
    • 0030986183 scopus 로고    scopus 로고
    • Abnormal dendritic spines in fragile X knockout mice: Maturation and pruning deficits
    • Comery TA, Harris JB, Willems PJ, Oostra BA, Irwin SA, et al. 1997. Abnormal dendritic spines in fragile X knockout mice: maturation and pruning deficits. PNAS 94:5401-4
    • (1997) PNAS , vol.94 , pp. 5401-5404
    • Comery, T.A.1    Harris, J.B.2    Willems, P.J.3    Oostra, B.A.4    Irwin, S.A.5
  • 30
    • 0027997686 scopus 로고
    • Motor deficit and impairment of synaptic plasticity in mice lacking mGluR1
    • Conquet F, Bashir ZI, Davies CH, DanielH, Ferraguti F, et al. 1994. Motor deficit and impairment of synaptic plasticity in mice lacking mGluR1. Nature 372:237-43
    • (1994) Nature , vol.372 , pp. 237-243
    • Conquet, F.1    Bashir, Z.I.2    Davies, C.H.3    Daniel, H.4    Ferraguti, F.5
  • 31
    • 79952245139 scopus 로고    scopus 로고
    • Kainate receptors coming of age: Milestones of two decades of research
    • Contractor A, Mulle C, Swanson GT. 2011. Kainate receptors coming of age: milestones of two decades of research. Trends Neurosci. 34:154-63
    • (2011) Trends Neurosci. , vol.34 , pp. 154-163
    • Contractor, A.1    Mulle, C.2    Swanson, G.T.3
  • 32
    • 79956310560 scopus 로고    scopus 로고
    • Synaptic targeting and functional modulation ofGluK1 kainate receptors by the auxiliary neuropilin and tolloid-like (NETO) proteins
    • Copits BA, Robbins JS, Frausto S, SwansonGT. 2011. Synaptic targeting and functional modulation ofGluK1 kainate receptors by the auxiliary neuropilin and tolloid-like (NETO) proteins. J. Neurosci. 31:7334-40
    • (2011) J. Neurosci. , vol.31 , pp. 7334-7340
    • Copits, B.A.1    Robbins, J.S.2    Frausto, S.3    Swanson, G.T.4
  • 33
    • 0036798191 scopus 로고    scopus 로고
    • Deletion of the mental retardation gene Gdi1 impairs associative memory and alters social behavior in mice
    • D'Adamo P, Welzl H, Papadimitriou S, Raffaele di Barletta M, Tiveron C, et al. 2002. Deletion of the mental retardation gene Gdi1 impairs associative memory and alters social behavior in mice. Hum. Mol. Genet. 11:2567-80
    • (2002) Hum. Mol. Genet. , vol.11 , pp. 2567-2580
    • D'adamo, P.1    Welzl, H.2    Papadimitriou, S.3    Raffaele Di Barletta, M.4    Tiveron, C.5
  • 34
    • 24644490120 scopus 로고    scopus 로고
    • Reduced cortical activity due to a shift in the balance between excitation and inhibition in a mouse model of Rett syndrome
    • Dani VS, Chang Q, Maffei A, Turrigiano GG, Jaenisch R, Nelson SB. 2005. Reduced cortical activity due to a shift in the balance between excitation and inhibition in a mouse model of Rett syndrome. PNAS 102:12560-65
    • (2005) PNAS , vol.102 , pp. 12560-12565
    • Dani, V.S.1    Chang, Q.2    Maffei, A.3    Turrigiano, G.G.4    Jaenisch, R.5    Nelson, S.B.6
  • 35
    • 84886953546 scopus 로고    scopus 로고
    • The translation of translational control by FMRP: Therapeutic targets for FXS
    • Darnell JC, Klann E. 2013. The translation of translational control by FMRP: therapeutic targets for FXS. Nat. Neurosci. 16:1530-36
    • (2013) Nat. Neurosci. , vol.16 , pp. 1530-1536
    • Darnell, J.C.1    Klann, E.2
  • 36
    • 0026753733 scopus 로고
    • The significance of age of onset for schizophrenia
    • DeLisi LE. 1992. The significance of age of onset for schizophrenia. Schizophr. Bull. 18:209-15
    • (1992) Schizophr. Bull. , vol.18 , pp. 209-215
    • Delisi, L.E.1
  • 38
    • 49149088555 scopus 로고    scopus 로고
    • Reversal of learning deficits in a Tsc2+/ mouse model of tuberous sclerosis
    • Ehninger D, Han S, Shilyansky C, Zhou Y, LiW, et al. 2008a. Reversal of learning deficits in a Tsc2+/ mouse model of tuberous sclerosis. Nat. Med. 14:843-48
    • (2008) Nat. Med. , vol.14 , pp. 843-848
    • Ehninger, D.1    Han, S.2    Shilyansky, C.3    Zhou, Y.4    Li, W.5
  • 41
    • 80051998693 scopus 로고    scopus 로고
    • Autism-linked neuroligin-3 R451C mutation differentially alters hippocampal and cortical synaptic function
    • Etherton MR, Földy C, Sharma M, Tabuchi K, Liu X, et al. 2011a. Autism-linked neuroligin-3 R451C mutation differentially alters hippocampal and cortical synaptic function. PNAS 108:13764-69
    • (2011) PNAS , vol.108 , pp. 13764-13769
    • Etherton, M.R.1    Földy, C.2    Sharma, M.3    Tabuchi, K.4    Liu, X.5
  • 42
    • 79960627779 scopus 로고    scopus 로고
    • An autism-associated point mutation in the neuroligin cytoplasmic tail selectively impairs AMPA receptor-mediated synaptic transmission in hippocampus
    • Etherton MR, Tabuchi K, Sharma M, Ko J, Sudhof TC. 2011b. An autism-associated point mutation in the neuroligin cytoplasmic tail selectively impairs AMPA receptor-mediated synaptic transmission in hippocampus. EMBO J. 30:2908-19
    • (2011) EMBO J. , vol.30 , pp. 2908-2919
    • Etherton, M.R.1    Tabuchi, K.2    Sharma, M.3    Ko, J.4    Sudhof, T.C.5
  • 43
    • 67149141899 scopus 로고    scopus 로고
    • Targeted tandem affinity purification of PSD-95 recovers core postsynaptic complexes and schizophrenia susceptibility proteins
    • Fernández E, Collins MO, Uren RT, Kopanitsa MV, Komiyama NH, et al. 2009. Targeted tandem affinity purification of PSD-95 recovers core postsynaptic complexes and schizophrenia susceptibility proteins. Mol. Syst. Biol. 5:269
    • (2009) Mol. Syst. Biol. , vol.5 , pp. 269
    • Fernández, E.1    Collins, M.O.2    Uren, R.T.3    Kopanitsa, M.V.4    Komiyama, N.H.5
  • 44
    • 78649753616 scopus 로고    scopus 로고
    • Association of mouse Dlg4 (PSD-95) gene deletion and human DLG4 gene variation with phenotypes relevant to autism spectrum disorders and Williams' syndrome
    • Feyder M, Karlsson RM, Mathur P, LymanM, Bock R, et al. 2010. Association of mouse Dlg4 (PSD-95) gene deletion and human DLG4 gene variation with phenotypes relevant to autism spectrum disorders and Williams' syndrome. Am. J. Psychiatry 167:1508-17
    • (2010) Am. J. Psychiatry , vol.167 , pp. 1508-1517
    • Feyder, M.1    Karlsson, R.M.2    Mathur, P.3    Lyman, M.4    Bock, R.5
  • 46
    • 84899976761 scopus 로고    scopus 로고
    • Comprehensive behavioral study of mGluR3 knockout mice: Implication in schizophrenia related endophenotypes
    • Fujioka R, Nii T, Iwaki A, Shibata A, Ito I, et al. 2014. Comprehensive behavioral study of mGluR3 knockout mice: implication in schizophrenia related endophenotypes. Mol. Brain 7:31
    • (2014) Mol. Brain , vol.7 , pp. 31
    • Fujioka, R.1    Nii, T.2    Iwaki, A.3    Shibata, A.4    Ito, I.5
  • 47
    • 77952374703 scopus 로고    scopus 로고
    • De novo mutations in the gene encoding the synaptic scaffolding protein SHANK3 in patients ascertained for schizophrenia
    • Gauthier J, Champagne N, Lafrenière RG, Xiong L, Spiegelman D, et al. 2010. De novo mutations in the gene encoding the synaptic scaffolding protein SHANK3 in patients ascertained for schizophrenia. PNAS 107:7863-68
    • (2010) PNAS , vol.107 , pp. 7863-7868
    • Gauthier, J.1    Champagne, N.2    Lafrenière, R.G.3    Xiong, L.4    Spiegelman, D.5
  • 48
    • 0242446216 scopus 로고    scopus 로고
    • Characterization of the human glutamate receptor subunit 3 gene (GRIA3), a candidate for bipolar disorder and nonspecific X-linked mental retardation
    • Gécz J, Barnett S, Liu J, Hollway G, Donnelly A, et al. 1999. Characterization of the human glutamate receptor subunit 3 gene (GRIA3), a candidate for bipolar disorder and nonspecific X-linked mental retardation. Genomics 62:356-68
    • (1999) Genomics , vol.62 , pp. 356-368
    • Gécz, J.1    Barnett, S.2    Liu, J.3    Hollway, G.4    Donnelly, A.5
  • 49
    • 77953776675 scopus 로고    scopus 로고
    • Strong synaptic transmission impact by copy number variations in schizophrenia
    • Glessner JT, Reilly MP, Kim CE, Takahashi N, Albano A, et al. 2010. Strong synaptic transmission impact by copy number variations in schizophrenia. PNAS 107:10584-89
    • (2010) PNAS , vol.107 , pp. 10584-10589
    • Glessner, J.T.1    Reilly, M.P.2    Kim, C.E.3    Takahashi, N.4    Albano, A.5
  • 50
    • 79953191735 scopus 로고    scopus 로고
    • MHCI negatively regulates synapse density during the establishment of cortical connections
    • Glynn MW, Elmer BM, Garay PA, Liu XB, Needleman LA, et al. 2011. MHCI negatively regulates synapse density during the establishment of cortical connections. Nat. Neurosci. 14:442-51
    • (2011) Nat. Neurosci. , vol.14 , pp. 442-451
    • Glynn, M.W.1    Elmer, B.M.2    Garay, P.A.3    Liu, X.B.4    Needleman, L.A.5
  • 51
    • 34249849030 scopus 로고    scopus 로고
    • Regulation of CNS synapses by neuronal MHC class i
    • Goddard CA, Butts DA, Shatz CJ. 2007. Regulation of CNS synapses by neuronal MHC class I. PNAS 104:6828-33
    • (2007) PNAS , vol.104 , pp. 6828-6833
    • Goddard, C.A.1    Butts, D.A.2    Shatz, C.J.3
  • 53
    • 0014107491 scopus 로고
    • A polygenic theory of schizophrenia
    • Gottesman II, Shields J. 1967. A polygenic theory of schizophrenia. PNAS 58:199-205
    • (1967) PNAS , vol.58 , pp. 199-205
    • Gottesman, I.I.1    Shields, J.2
  • 54
    • 79551596834 scopus 로고    scopus 로고
    • Concerted action of zinc and ProSAP/Shank in synaptogenesis and synapse maturation
    • Grabrucker AM, Knight MJ, Proepper C, Bockmann J, Joubert M, et al. 2011a. Concerted action of zinc and ProSAP/Shank in synaptogenesis and synapse maturation. EMBO J. 30:569-81
    • (2011) EMBO J. , vol.30 , pp. 569-581
    • Grabrucker, A.M.1    Knight, M.J.2    Proepper, C.3    Bockmann, J.4    Joubert, M.5
  • 56
    • 77649083119 scopus 로고    scopus 로고
    • The Angelman Syndrome protein Ube3A regulates synapse development by ubiquitinating Arc
    • Greer PL, Hanayama R, Bloodgood BL, Mardinly AR, Lipton DM, et al. 2010. The Angelman Syndrome protein Ube3A regulates synapse development by ubiquitinating Arc. Cell 140:704-16
    • (2010) Cell , vol.140 , pp. 704-716
    • Greer, P.L.1    Hanayama, R.2    Bloodgood, B.L.3    Mardinly, A.R.4    Lipton, D.M.5
  • 57
    • 69949177829 scopus 로고    scopus 로고
    • Recurrent rearrangements in synaptic and neurodevelopmental genes and shared biologic pathways in schizophrenia, autism, and mental retardation
    • Guilmatre A, Dubourg C, Mosca AL, Legallic S, Goldenberg A, et al. 2009. Recurrent rearrangements in synaptic and neurodevelopmental genes and shared biologic pathways in schizophrenia, autism, and mental retardation. Arch. Gen. Psychiatry 66:947-56
    • (2009) Arch. Gen. Psychiatry , vol.66 , pp. 947-956
    • Guilmatre, A.1    Dubourg, C.2    Mosca, A.L.3    Legallic, S.4    Goldenberg, A.5
  • 58
    • 84881219396 scopus 로고    scopus 로고
    • In a double-blind, randomized and placebo-controlled trial, adjuvant memantine improved symptoms in inpatients suffering from refractory obsessive-compulsive disorders (OCD)
    • Haghighi M, Jahangard L, Mohammad-Beigi H, Bajoghli H, Hafezian H, et al. 2013. In a double-blind, randomized and placebo-controlled trial, adjuvant memantine improved symptoms in inpatients suffering from refractory obsessive-compulsive disorders (OCD). Psychopharmacology 228:633-40
    • (2013) Psychopharmacology , vol.228 , pp. 633-640
    • Haghighi, M.1    Jahangard, L.2    Mohammad-Beigi, H.3    Bajoghli, H.4    Hafezian, H.5
  • 59
    • 80051944739 scopus 로고    scopus 로고
    • Genetic heritability and shared environmental factors among twin pairs with autism
    • Hallmayer J, Cleveland S, Torres A, Phillips J, Cohen B, et al. 2011. Genetic heritability and shared environmental factors among twin pairs with autism. Arch. Gen. Psychiatry 68:1095-102
    • (2011) Arch. Gen. Psychiatry , vol.68 , pp. 1095-1102
    • Hallmayer, J.1    Cleveland, S.2    Torres, A.3    Phillips, J.4    Cohen, B.5
  • 61
    • 67650090920 scopus 로고    scopus 로고
    • De novo STXBP1 mutations in mental retardation and nonsyndromic epilepsy
    • Hamdan FF, Piton A, Gauthier J, Lortie A, Dubeau F, et al. 2009b. De novo STXBP1 mutations in mental retardation and nonsyndromic epilepsy. Ann. Neurol. 65:748-53
    • (2009) Ann. Neurol. , vol.65 , pp. 748-753
    • Hamdan, F.F.1    Piton, A.2    Gauthier, J.3    Lortie, A.4    Dubeau, F.5
  • 62
    • 77649192502 scopus 로고    scopus 로고
    • Disrupted-in-Schizophrenia 1 (DISC1) regulates spines of the glutamate synapse via Rac1
    • Hayashi-Takagi A, Takaki M, Graziane N, Seshadri S, Murdoch H, et al. 2010. Disrupted-in-Schizophrenia 1 (DISC1) regulates spines of the glutamate synapse via Rac1. Nat. Neurosci. 13:327-32
    • (2010) Nat. Neurosci. , vol.13 , pp. 327-332
    • Hayashi-Takagi, A.1    Takaki, M.2    Graziane, N.3    Seshadri, S.4    Murdoch, H.5
  • 63
    • 0026483297 scopus 로고
    • Positive feedback of glutamate exocytosis by metabotropic presynaptic receptor stimulation
    • Herrero I, Miras-Portugal MT, Sánchez-Prieto J. 1992. Positive feedback of glutamate exocytosis by metabotropic presynaptic receptor stimulation. Nature 360:163-66
    • (1992) Nature , vol.360 , pp. 163-166
    • Herrero, I.1    Miras-Portugal, M.T.2    Sánchez-Prieto, J.3
  • 64
    • 84887009409 scopus 로고    scopus 로고
    • AMPARs and synaptic plasticity: The last 25 years
    • Huganir RL, Nicoll RA. 2013. AMPARs and synaptic plasticity: the last 25 years. Neuron 80:704-17
    • (2013) Neuron , vol.80 , pp. 704-717
    • Huganir, R.L.1    Nicoll, R.A.2
  • 67
    • 84905993620 scopus 로고    scopus 로고
    • Sorting Nexin 27 regulates basal and activity-dependent trafficking of AMPARs
    • Hussain NK, Diering GH, Sole J, Anggono V, Huganir RL. 2014. Sorting Nexin 27 regulates basal and activity-dependent trafficking of AMPARs. PNAS 111:11840-45
    • (2014) PNAS , vol.111 , pp. 11840-11845
    • Hussain, N.K.1    Diering, G.H.2    Sole, J.3    Anggono, V.4    Huganir, R.L.5
  • 68
    • 72049108920 scopus 로고    scopus 로고
    • Increased dendritic spine densities on cortical projection neurons in autism spectrum disorders
    • Hutsler JJ, Zhang H. 2010. Increased dendritic spine densities on cortical projection neurons in autism spectrum disorders. Brain Res. 1309:83-94
    • (2010) Brain Res. , vol.1309 , pp. 83-94
    • Hutsler, J.J.1    Zhang, H.2
  • 69
    • 0035863624 scopus 로고    scopus 로고
    • Abnormal dendritic spine characteristics in the temporal and visual cortices of patients with fragile-X syndrome: A quantitative examination
    • Irwin SA, Patel B, IdupulapatiM, Harris JB, Crisostomo RA, et al. 2001. Abnormal dendritic spine characteristics in the temporal and visual cortices of patients with fragile-X syndrome: A quantitative examination. Am. J. Med. Genet. 98:161-67
    • (2001) Am. J. Med. Genet. , vol.98 , pp. 161-167
    • Irwin, S.A.1    Patel, B.2    Idupulapati, M.3    Harris, J.B.4    Crisostomo, R.A.5
  • 70
    • 40349096250 scopus 로고    scopus 로고
    • Reduced social interaction and ultrasonic communication in a mouse model of monogenic heritable autism
    • Jamain S, Radyushkin K, Hammerschmidt K, Granon S, Boretius S, et al. 2008. Reduced social interaction and ultrasonic communication in a mouse model of monogenic heritable autism. PNAS 105:1710-15
    • (2008) PNAS , vol.105 , pp. 1710-1715
    • Jamain, S.1    Radyushkin, K.2    Hammerschmidt, K.3    Granon, S.4    Boretius, S.5
  • 71
    • 84898917488 scopus 로고    scopus 로고
    • Autism-related neuroligin-3 mutation alters social behavior and spatial learning
    • Jaramillo TC, Liu S, Pettersen A, Birnbaum SG, Powell CM. 2014. Autism-related neuroligin-3 mutation alters social behavior and spatial learning. Autism Res. 7:264-72
    • (2014) Autism Res. , vol.7 , pp. 264-272
    • Jaramillo, T.C.1    Liu, S.2    Pettersen, A.3    Birnbaum, S.G.4    Powell, C.M.5
  • 72
    • 84876070991 scopus 로고    scopus 로고
    • Modeling autism by SHANK gene mutations in mice
    • Jiang Y, Ehlers MD. 2013. Modeling autism by SHANK gene mutations in mice. Neuron 78:8-27
    • (2013) Neuron , vol.78 , pp. 8-27
    • Jiang, Y.1    Ehlers, M.D.2
  • 73
    • 66249116695 scopus 로고    scopus 로고
    • Modeling cognitive endophenotypes of schizophrenia inmice
    • Kellendonk C, Simpson EH, Kandel ER. 2009. Modeling cognitive endophenotypes of schizophrenia inmice. Trends Neurosci. 32:347-58
    • (2009) Trends Neurosci. , vol.32 , pp. 347-358
    • Kellendonk, C.1    Simpson, E.H.2    Kandel, E.R.3
  • 74
    • 59649114125 scopus 로고    scopus 로고
    • Synaptic AMPA receptor plasticity and behavior
    • Kessels HW, Malinow R. 2009. Synaptic AMPA receptor plasticity and behavior. Neuron 61:340-50
    • (2009) Neuron , vol.61 , pp. 340-350
    • Kessels, H.W.1    Malinow, R.2
  • 75
    • 34548450836 scopus 로고    scopus 로고
    • Loss of X-linked mental retardation gene oligophrenin1 in mice impairs spatial memory and leads to ventricular enlargement and dendritic spine immaturity
    • Khelfaoui M, Denis C, van Galen E, de Bock F, Schmitt A, et al. 2007. Loss of X-linked mental retardation gene oligophrenin1 in mice impairs spatial memory and leads to ventricular enlargement and dendritic spine immaturity. J. Neurosci. 27:9439-50
    • (2007) J. Neurosci. , vol.27 , pp. 9439-9450
    • Khelfaoui, M.1    Denis, C.2    Van Galen, E.3    De Bock, F.4    Schmitt, A.5
  • 76
    • 0037442509 scopus 로고    scopus 로고
    • The role of synapticGTPase-activating protein in neuronal development and synaptic plasticity
    • Kim JH, LeeHK, Takamiya K, HuganirRL. 2003. The role of synapticGTPase-activating protein in neuronal development and synaptic plasticity. J. Neurosci. 23:1119-24
    • (2003) J. Neurosci. , vol.23 , pp. 1119-1124
    • Kim, J.H.1    Lee, H.K.2    Takamiya, K.3    Huganir, R.L.4
  • 77
    • 0032055396 scopus 로고    scopus 로고
    • SynGAP: A synaptic RasGAP that associates with the PSD-95/SAP90 protein family
    • Kim JH, Liao D, Lau LF, Huganir RL. 1998. SynGAP: A synaptic RasGAP that associates with the PSD-95/SAP90 protein family. Neuron 20:683-91
    • (1998) Neuron , vol.20 , pp. 683-691
    • Kim, J.H.1    Liao, D.2    Lau, L.F.3    Huganir, R.L.4
  • 78
    • 84856225986 scopus 로고    scopus 로고
    • De novo CNV analysis implicates specific abnormalities of postsynaptic signalling complexes in the pathogenesis of schizophrenia
    • Kirov G, Pocklington AJ, Holmans P, Ivanov D, Ikeda M, et al. 2012. De novo CNV analysis implicates specific abnormalities of postsynaptic signalling complexes in the pathogenesis of schizophrenia. Mol. Psychiatry 17:142-53
    • (2012) Mol. Psychiatry , vol.17 , pp. 142-153
    • Kirov, G.1    Pocklington, A.J.2    Holmans, P.3    Ivanov, D.4    Ikeda, M.5
  • 79
    • 0031012849 scopus 로고    scopus 로고
    • UBE3A/E6-AP mutations cause Angelman syndrome
    • Kishino T, Lalande M, Wagstaff J. 1997. UBE3A/E6-AP mutations cause Angelman syndrome. Nat. Genet. 15:70-73
    • (1997) Nat. Genet. , vol.15 , pp. 70-73
    • Kishino, T.1    Lalande, M.2    Wagstaff, J.3
  • 80
    • 0037111835 scopus 로고    scopus 로고
    • SynGAP regulates ERK/MAPK signaling, synaptic plasticity, and learning in the complex with postsynaptic density 95 and NMDA receptor
    • Komiyama NH, Watabe AM, Carlisle HJ, Porter K, Charlesworth P, et al. 2002. SynGAP regulates ERK/MAPK signaling, synaptic plasticity, and learning in the complex with postsynaptic density 95 and NMDA receptor. J. Neurosci. 22:9721-32
    • (2002) J. Neurosci. , vol.22 , pp. 9721-9732
    • Komiyama, N.H.1    Watabe, A.M.2    Carlisle, H.J.3    Porter, K.4    Charlesworth, P.5
  • 81
    • 84893708713 scopus 로고    scopus 로고
    • A de novo convergence of autism genetics andmolecular neuroscience
    • KrummN, O'Roak BJ, Shendure J, Eichler EE. 2014. A de novo convergence of autism genetics andmolecular neuroscience. Trends Neurosci. 37:95-105
    • (2014) Trends Neurosci. , vol.37 , pp. 95-105
    • Krumm, N.1    O'roak, B.J.2    Shendure, J.3    Eichler, E.E.4
  • 82
    • 84856089057 scopus 로고    scopus 로고
    • Contributions of the D-serine pathway to schizophrenia
    • Labrie V, Wong AH, Roder JC. 2012. Contributions of the D-serine pathway to schizophrenia. Neuropharmacology 62:1484-503
    • (2012) Neuropharmacology , vol.62 , pp. 1484-1503
    • Labrie, V.1    Wong, A.H.2    Roder, J.C.3
  • 83
    • 70449245071 scopus 로고
    • Étude des chromosomes somatiques de neuf enfants mongoliens
    • Lejeune J, Gautier M, Turpin R. 1959. Étude des chromosomes somatiques de neuf enfants mongoliens. C. R. Acad. Sci. 248:1721-22
    • (1959) C. R. Acad. Sci. , vol.248 , pp. 1721-1722
    • Lejeune, J.1    Gautier, M.2    Turpin, R.3
  • 84
    • 0015209755 scopus 로고
    • Unique high affinity uptake systems for glycine, glutamic and aspartic acids in central nervous tissue of the rat
    • LoganWJ, Snyder SH. 1971. Unique high affinity uptake systems for glycine, glutamic and aspartic acids in central nervous tissue of the rat. Nature 234:297-99
    • (1971) Nature , vol.234 , pp. 297-299
    • Logan, W.J.1    Snyder, S.H.2
  • 85
    • 0036642290 scopus 로고    scopus 로고
    • RIM1: An edge for presynaptic plasticity
    • Lonart G. 2002. RIM1: An edge for presynaptic plasticity. Trends Neurosci. 25:329-32
    • (2002) Trends Neurosci. , vol.25 , pp. 329-332
    • Lonart, G.1
  • 86
    • 84867494020 scopus 로고    scopus 로고
    • Scaffold proteinHomer 1: Implications for neurological diseases
    • Luo P, Li X, FeiZ, PoonW. 2012. Scaffold proteinHomer 1: implications for neurological diseases. Neurochem. Int. 61:731-38
    • (2012) Neurochem. Int. , vol.61 , pp. 731-738
    • Luo, P.1    Li, X.2    Fei, Z.3    Poon, W.4
  • 87
    • 76849116197 scopus 로고    scopus 로고
    • Group 1 mGluR-dependent synaptic long-term depression: Mechanisms and implications for circuitry and disease
    • Luscher C, Huber KM. 2010. Group 1 mGluR-dependent synaptic long-term depression: mechanisms and implications for circuitry and disease. Neuron 65:445-59
    • (2010) Neuron , vol.65 , pp. 445-459
    • Luscher, C.1    Huber, K.M.2
  • 88
    • 79957560791 scopus 로고    scopus 로고
    • Angelman syndrome: Insights into genomic imprinting and neurodevelopmental phenotypes
    • Mabb AM, Judson MC, Zylka MJ, Philpot BD. 2011. Angelman syndrome: insights into genomic imprinting and neurodevelopmental phenotypes. Trends Neurosci. 34:293-303
    • (2011) Trends Neurosci. , vol.34 , pp. 293-303
    • Mabb, A.M.1    Judson, M.C.2    Zylka, M.J.3    Philpot, B.D.4
  • 89
    • 77958487953 scopus 로고    scopus 로고
    • EphB-mediated degradation of theRhoAGEF Ephexin5 relieves a developmental brake on excitatory synapse formation
    • Margolis SS, Salogiannis J, LiptonDM, Mandel-Brehm C, Wills ZP, et al. 2010. EphB-mediated degradation of theRhoAGEF Ephexin5 relieves a developmental brake on excitatory synapse formation. Cell 143:442-55
    • (2010) Cell , vol.143 , pp. 442-455
    • Margolis, S.S.1    Salogiannis, J.2    Lipton, D.M.3    Mandel-Brehm, C.4    Wills, Z.P.5
  • 90
    • 84901596062 scopus 로고    scopus 로고
    • Genome-scale neurogenetics: Methodology and meaning
    • McCarroll SA, Feng G, Hyman SE. 2014. Genome-scale neurogenetics: methodology and meaning. Nat. Neurosci. 17:756-63
    • (2014) Nat. Neurosci. , vol.17 , pp. 756-763
    • McCarroll, S.A.1    Feng, G.2    Hyman, S.E.3
  • 91
    • 79955645912 scopus 로고    scopus 로고
    • Mechanisms of excitatory synapse maturation by trans-synaptic organizing complexes
    • McMahon SA, Dáz E. 2011. Mechanisms of excitatory synapse maturation by trans-synaptic organizing complexes. Curr. Opin. Neurobiol. 21:221-27
    • (2011) Curr. Opin. Neurobiol. , vol.21 , pp. 221-227
    • McMahon, S.A.1    Dáz, E.2
  • 92
    • 79953194483 scopus 로고    scopus 로고
    • Gain-of-function glutamate receptor interacting protein 1 variants alter GluA2 recycling and surface distribution in patients with autism
    • Mejias R, Adamczyk A, Anggono V, Niranjan T, Thomas GM, et al. 2011. Gain-of-function glutamate receptor interacting protein 1 variants alter GluA2 recycling and surface distribution in patients with autism. PNAS 108:4920-25
    • (2011) PNAS , vol.108 , pp. 4920-4925
    • Mejias, R.1    Adamczyk, A.2    Anggono, V.3    Niranjan, T.4    Thomas, G.M.5
  • 93
    • 79955030459 scopus 로고    scopus 로고
    • Autism spectrum disorders-a genetics review
    • Miles JH. 2011. Autism spectrum disorders-a genetics review. Genet. Med. 13:278-94
    • (2011) Genet. Med. , vol.13 , pp. 278-294
    • Miles, J.H.1
  • 95
    • 0033588176 scopus 로고    scopus 로고
    • Mice with reduced NMDA receptor expression display behaviors related to schizophrenia
    • Mohn AR, Gainetdinov RR, Caron MG, Koller BH. 1999. Mice with reduced NMDA receptor expression display behaviors related to schizophrenia. Cell 98:427-36
    • (1999) Cell , vol.98 , pp. 427-436
    • Mohn, A.R.1    Gainetdinov, R.R.2    Caron, M.G.3    Koller, B.H.4
  • 96
    • 84878213451 scopus 로고    scopus 로고
    • Low doses of theNMDAreceptor antagonists, MK-801, PEAQX, and ifenprodil, induces social facilitation in adolescent male rats
    • MoralesM, VarlinskayaEI, SpearLP. 2013. Low doses of theNMDAreceptor antagonists, MK-801, PEAQX, and ifenprodil, induces social facilitation in adolescent male rats. Behav. Brain Res. 250:18-22
    • (2013) Behav. Brain Res. , vol.250 , pp. 18-22
    • Morales, M.1    Varlinskaya, E.I.2    Spear, L.P.3
  • 97
    • 54949150182 scopus 로고    scopus 로고
    • Palmitoylation-dependent neurodevelopmental deficits in a mouse model of 22q11 microdeletion
    • Mukai J, Dhilla A, Drew LJ, Stark KL, Cao L, et al. 2008. Palmitoylation-dependent neurodevelopmental deficits in a mouse model of 22q11 microdeletion. Nat. Neurosci. 11:1302-10
    • (2008) Nat. Neurosci. , vol.11 , pp. 1302-1310
    • Mukai, J.1    Dhilla, A.2    Drew, L.J.3    Stark, K.L.4    Cao, L.5
  • 98
    • 3042804077 scopus 로고    scopus 로고
    • Evidence that the gene encoding ZDHHC8 contributes to the risk of schizophrenia
    • Mukai J, Liu H, Burt RA, Swor DE, Lai WS, et al. 2004. Evidence that the gene encoding ZDHHC8 contributes to the risk of schizophrenia. Nat. Genet. 36:725-31
    • (2004) Nat. Genet. , vol.36 , pp. 725-731
    • Mukai, J.1    Liu, H.2    Burt, R.A.3    Swor, D.E.4    Lai, W.S.5
  • 99
    • 66149180800 scopus 로고    scopus 로고
    • The Rho-linkedmental retardation protein oligophrenin-1 controls synapse maturation and plasticity by stabilizing AMPA receptors
    • NadifKasri N, Nakano-Kobayashi A, Malinow R, Li B, Van Aelst L. 2009. The Rho-linkedmental retardation protein oligophrenin-1 controls synapse maturation and plasticity by stabilizing AMPA receptors. Genes Dev. 23:1289-302
    • (2009) Genes Dev. , vol.23 , pp. 1289-1302
    • Nadifkasri, N.1    Nakano-Kobayashi, A.2    Malinow, R.3    Li, B.4    Van Aelst, L.5
  • 100
    • 0033165926 scopus 로고    scopus 로고
    • Shank, a novel family of postsynaptic density proteins that binds to the NMDA receptor/PSD-95/GKAP complex and cortactin
    • Naisbitt S, Kim E, Tu JC, Xiao B, Sala C, et al. 1999. Shank, a novel family of postsynaptic density proteins that binds to the NMDA receptor/PSD-95/GKAP complex and cortactin. Neuron 23:569-82
    • (1999) Neuron , vol.23 , pp. 569-582
    • Naisbitt, S.1    Kim, E.2    Tu, J.C.3    Xiao, B.4    Sala, C.5
  • 101
    • 67649886975 scopus 로고    scopus 로고
    • The Rho-linked mental retardation protein OPHN1 controls synaptic vesicle endocytosis via endophilin A1
    • Nakano-Kobayashi A, Nadif Kasri N, Newey SE, Van Aelst L. 2009. The Rho-linked mental retardation protein OPHN1 controls synaptic vesicle endocytosis via endophilin A1. Curr. Biol. 19:1133-39
    • (2009) Curr. Biol. , vol.19 , pp. 1133-1139
    • Nakano-Kobayashi, A.1    Nadif Kasri, N.2    Newey, S.E.3    Van Aelst, L.4
  • 102
    • 84883421597 scopus 로고    scopus 로고
    • HCclass i immune proteins are critical for hippocampus-dependent memory and gate NMDAR-dependent hippocampal long-term depression
    • Nelson PA, Sage JR, Wood SC, DavenportCM, Anagnostaras SG, BoulangerLM. 2013. MHCclass I immune proteins are critical for hippocampus-dependent memory and gate NMDAR-dependent hippocampal long-term depression. Learn. Mem. 20:505-17
    • (2013) Learn. Mem. , vol.20 , pp. 505-517
    • Nelson, P.A.1    Sage, J.R.2    Wood, S.C.3    Davenport, C.M.4    Anagnostaras, S.G.5    Boulanger, L.M.6
  • 103
    • 84887955339 scopus 로고    scopus 로고
    • DSM-5: A collection of psychiatrist views on the changes, controversies, and future directions
    • Nemeroff CB, Weinberger D, Rutter M, MacMillan HL, Bryant RA, et al. 2013. DSM-5: A collection of psychiatrist views on the changes, controversies, and future directions. BMC Med. 11:202
    • (2013) BMC Med. , vol.11 , pp. 202
    • Nemeroff, C.B.1    Weinberger, D.2    Rutter, M.3    Macmillan, H.L.4    Bryant, R.A.5
  • 104
    • 43449102784 scopus 로고    scopus 로고
    • Glutamate receptor dynamics in dendriticmicrodomains
    • Newpher TM, Ehlers MD. 2008. Glutamate receptor dynamics in dendriticmicrodomains. Neuron 58:472-97
    • (2008) Neuron , vol.58 , pp. 472-497
    • Newpher, T.M.1    Ehlers, M.D.2
  • 105
    • 33644674232 scopus 로고    scopus 로고
    • Auxiliary subunits assist AMPA-type glutamate receptors
    • Nicoll RA, Tomita S, Bredt DS. 2006. Auxiliary subunits assist AMPA-type glutamate receptors. Science 311:1253-56
    • (2006) Science , vol.311 , pp. 1253-1256
    • Nicoll, R.A.1    Tomita, S.2    Bredt, D.S.3
  • 106
    • 77949516412 scopus 로고    scopus 로고
    • Metabotropic glutamate receptors: Physiology, pharmacology, and disease
    • Niswender CM, Conn PJ. 2010. Metabotropic glutamate receptors: physiology, pharmacology, and disease. Annu. Rev. Pharmacol. Toxicol. 50:295-322
    • (2010) Annu. Rev. Pharmacol. Toxicol. , vol.50 , pp. 295-322
    • Niswender, C.M.1    Conn, P.J.2
  • 108
    • 84988267086 scopus 로고    scopus 로고
    • Glutamate networks implicate cognitive impairments in schizophrenia: Genome-wide association studies of 52 cognitive phenotypes
    • In press
    • Ohi K, Hashimoto R, Ikeda M, Yamamori H, Yasuda Y, et al. 2014. Glutamate networks implicate cognitive impairments in schizophrenia: genome-wide association studies of 52 cognitive phenotypes. Schizophr. Bull. In press. doi: 10. 1093/schbul/
    • (2014) Schizophr. Bull
    • Ohi, K.1    Hashimoto, R.2    Ikeda, M.3    Yamamori, H.4    Yasuda, Y.5
  • 109
    • 77957012316 scopus 로고    scopus 로고
    • Specific involvement of postsynaptic GluN2B-containingNMDAreceptors in the developmental elimination of corticospinal synapses
    • Ohno T, Maeda H, Murabe N, Kamiyama T, Yoshioka N, et al. 2010. Specific involvement of postsynaptic GluN2B-containingNMDAreceptors in the developmental elimination of corticospinal synapses. PNAS 107:15252-57
    • (2010) PNAS , vol.107 , pp. 15252-15257
    • Ohno, T.1    Maeda, H.2    Murabe, N.3    Kamiyama, T.4    Yoshioka, N.5
  • 110
    • 84871448593 scopus 로고    scopus 로고
    • Multiplex targeted sequencing identifies recurrently mutated genes in autism spectrum disorders
    • O'Roak BJ, Vives L, Fu W, Egertson JD, Stanaway IB, et al. 2012. Multiplex targeted sequencing identifies recurrently mutated genes in autism spectrum disorders. Science 338:1619-22
    • (2012) Science , vol.338 , pp. 1619-1622
    • O'roak, B.J.1    Vives, L.2    Fu, W.3    Egertson, J.D.4    Stanaway, I.B.5
  • 111
    • 74849134916 scopus 로고    scopus 로고
    • A postsynaptic signaling pathway that may account for the cognitive defect due to IL1RAPL1 mutation
    • Pavlowsky A, Gianfelice A, Pallotto M, Zanchi A, Vara H, et al. 2010. A postsynaptic signaling pathway that may account for the cognitive defect due to IL1RAPL1 mutation. Curr. Biol. : CB 20:103-15
    • (2010) Curr. Biol. : CB , vol.20 , pp. 103-115
    • Pavlowsky, A.1    Gianfelice, A.2    Pallotto, M.3    Zanchi, A.4    Vara, H.5
  • 112
    • 33947537457 scopus 로고    scopus 로고
    • Fragile X mental retardation protein induces synapse loss through acute postsynaptic translational regulation
    • Pfeiffer BE, Huber KM. 2007. Fragile X mental retardation protein induces synapse loss through acute postsynaptic translational regulation. J. Neurosci. 27:3120-30
    • (2007) J. Neurosci. , vol.27 , pp. 3120-3130
    • Pfeiffer, B.E.1    Huber, K.M.2
  • 113
    • 0025833298 scopus 로고
    • Absence of expression of the FMR-1 gene in fragile X syndrome
    • Pieretti M, Zhang FP, Fu YH, Warren ST, Oostra BA, et al. 1991. Absence of expression of the FMR-1 gene in fragile X syndrome. Cell 66:817-22
    • (1991) Cell , vol.66 , pp. 817-822
    • Pieretti, M.1    Zhang, F.P.2    Fu, Y.H.3    Warren, S.T.4    Oostra, B.A.5
  • 114
    • 84893904007 scopus 로고    scopus 로고
    • A polygenic burden of rare disruptive mutations in schizophrenia
    • Purcell SM, Moran JL, Fromer M, Ruderfer D, Solovieff N, et al. 2014. A polygenic burden of rare disruptive mutations in schizophrenia. Nature 506:185-90
    • (2014) Nature , vol.506 , pp. 185-190
    • Purcell, S.M.1    Moran, J.L.2    Fromer, M.3    Ruderfer, D.4    Solovieff, N.5
  • 115
  • 116
    • 67149127032 scopus 로고    scopus 로고
    • Neuroligin-3-deficient mice:model of a monogenic heritable form of autism with an olfactory deficit
    • Radyushkin K, Hammerschmidt K, Boretius S, Varoqueaux F, El-Kordi A, et al. 2009. Neuroligin-3-deficient mice:model of a monogenic heritable form of autism with an olfactory deficit. Genes Brain Behav. 8:416-25
    • (2009) Genes Brain Behav. , vol.8 , pp. 416-425
    • Radyushkin, K.1    Hammerschmidt, K.2    Boretius, S.3    Varoqueaux, F.4    El-Kordi, A.5
  • 117
    • 2542435173 scopus 로고    scopus 로고
    • A case of autism with an interstitial deletion on 4q leading to hemizygosity for genes encoding for glutamine and glycine neurotransmitter receptor sub-units (AMPA 2, GLRA3, GLRB) and neuropeptide receptors NPY1R, NPY5R
    • Ramanathan S, Woodroffe A, Flodman PL, Mays LZ, Hanouni M, et al. 2004. A case of autism with an interstitial deletion on 4q leading to hemizygosity for genes encoding for glutamine and glycine neurotransmitter receptor sub-units (AMPA 2, GLRA3, GLRB) and neuropeptide receptors NPY1R, NPY5R. BMC Med. Genet. 5:10
    • (2004) BMC Med. Genet. , vol.5 , pp. 10
    • Ramanathan, S.1    Woodroffe, A.2    Flodman, P.L.3    Mays, L.Z.4    Hanouni, M.5
  • 118
    • 0029114706 scopus 로고
    • Amousemodel for Down syndrome exhibits learning and behaviour deficits
    • Reeves RH, Irving NG, Moran TH, Wohn A, Kitt C, et al. 1995. Amousemodel for Down syndrome exhibits learning and behaviour deficits. Nat. Genet. 11:177-84
    • (1995) Nat. Genet. , vol.11 , pp. 177-184
    • Reeves, R.H.1    Irving, N.G.2    Moran, T.H.3    Wohn, A.4    Kitt, C.5
  • 119
    • 58149340280 scopus 로고    scopus 로고
    • Mouse models of Rett syndrome: From behavioural phenotyping to preclinical evaluation of new therapeutic approaches
    • Ricceri L, De Filippis B, Laviola G. 2008. Mouse models of Rett syndrome: from behavioural phenotyping to preclinical evaluation of new therapeutic approaches. Behav. Pharmacol. 19:501-17
    • (2008) Behav. Pharmacol. , vol.19 , pp. 501-517
    • Ricceri, L.1    De Filippis, B.2    Laviola, G.3
  • 120
    • 34548085412 scopus 로고    scopus 로고
    • Elevated NMDA receptor levels and enhanced postsynaptic long-term potentiation induced by prenatal exposure to valproic acid
    • Rinaldi T, Kulangara K, Antoniello K, Markram H. 2007. Elevated NMDA receptor levels and enhanced postsynaptic long-term potentiation induced by prenatal exposure to valproic acid. PNAS 104:13501-506
    • (2007) PNAS , vol.104 , pp. 13501-13506
    • Rinaldi, T.1    Kulangara, K.2    Antoniello, K.3    Markram, H.4
  • 121
    • 84925778664 scopus 로고    scopus 로고
    • The role of glutamate and its receptors in autism and the use of glutamate receptor antagonists in treatment
    • Rojas D. 2014. The role of glutamate and its receptors in autism and the use of glutamate receptor antagonists in treatment. J. Neural Transm. 121:891-905
    • (2014) J. Neural Transm. , vol.121 , pp. 891-905
    • Rojas, D.1
  • 122
    • 44349096827 scopus 로고    scopus 로고
    • De novo mutations in the gene encoding STXBP1 (MUNC18-1) cause early infantile epileptic encephalopathy
    • Saitsu H, Kato M, Mizuguchi T, Hamada K, Osaka H, et al. 2008. De novo mutations in the gene encoding STXBP1 (MUNC18-1) cause early infantile epileptic encephalopathy. Nat. Genet. 40:782-88
    • (2008) Nat. Genet. , vol.40 , pp. 782-788
    • Saitsu, H.1    Kato, M.2    Mizuguchi, T.3    Hamada, K.4    Osaka, H.5
  • 123
    • 0028813106 scopus 로고
    • Reduced hippocampal LTP and spatial learning in mice lacking NMDA receptor 1 subunit
    • Sakimura K, Kutsuwada T, Ito I, Manabe T, Takayama C, et al. 1995. Reduced hippocampal LTP and spatial learning in mice lacking NMDA receptor 1 subunit. Nature 373:151-55
    • (1995) Nature , vol.373 , pp. 151-155
    • Sakimura, K.1    Kutsuwada, T.2    Ito, I.3    Manabe, T.4    Takayama, C.5
  • 124
    • 0034879863 scopus 로고    scopus 로고
    • Regulation of dendritic spine morphology and synaptic function by Shank and Homer
    • Sala C, Piëch V, Wilson NR, Passafaro M, Liu G, Sheng M. 2001. Regulation of dendritic spine morphology and synaptic function by Shank and Homer. Neuron 31:115-30
    • (2001) Neuron , vol.31 , pp. 115-130
    • Sala, C.1    Piëch, V.2    Wilson, N.R.3    Passafaro, M.4    Liu, G.5    Sheng, M.6
  • 125
    • 84871558287 scopus 로고    scopus 로고
    • Diversity in NMDA receptor composition: Many regulators, many consequences
    • Sanz-Clemente A, Nicoll RA, Roche KW. 2013. Diversity in NMDA receptor composition: many regulators, many consequences. Neuroscientist 19:62-75
    • (2013) Neuroscientist , vol.19 , pp. 62-75
    • Sanz-Clemente, A.1    Nicoll, R.A.2    Roche, K.W.3
  • 126
    • 0034625250 scopus 로고    scopus 로고
    • Neuroligin expressed in nonneuronal cells triggers presynaptic development in contacting axons
    • Scheiffele P, Fan J, Choih J, Fetter R, Serafini T. 2000. Neuroligin expressed in nonneuronal cells triggers presynaptic development in contacting axons. Cell 101:657-69
    • (2000) Cell , vol.101 , pp. 657-669
    • Scheiffele, P.1    Fan, J.2    Choih, J.3    Fetter, R.4    Serafini, T.5
  • 127
    • 84904804929 scopus 로고    scopus 로고
    • Biological insights from 108 schizophreniaassociated genetic loci
    • Schizophr. Work. Group Psychiatr. Genomics Consort
    • Schizophr. Work. Group Psychiatr. Genomics Consort. 2014. Biological insights from 108 schizophreniaassociated genetic loci. Nature 511:421-27
    • (2014) Nature , vol.511 , pp. 421-427
  • 128
    • 84862274500 scopus 로고    scopus 로고
    • Autistic-like behaviours and hyperactivity in mice lacking ProSAP1/Shank2
    • Schmeisser MJ, Ey E, Wegener S, Bockmann J, Stempel AV, et al. 2012. Autistic-like behaviours and hyperactivity in mice lacking ProSAP1/Shank2. Nature 486:256-60
    • (2012) Nature , vol.486 , pp. 256-260
    • Schmeisser, M.J.1    Ey, E.2    Wegener, S.3    Bockmann, J.4    Stempel, A.V.5
  • 129
    • 11144259318 scopus 로고    scopus 로고
    • Behavioral alterations in rats prenatally exposed to valproic acid: Animal model of autism
    • Schneider T, Przewlocki R. 2005. Behavioral alterations in rats prenatally exposed to valproic acid: Animal model of autism. Neuropsychopharmacology 30:80-89
    • (2005) Neuropsychopharmacology , vol.30 , pp. 80-89
    • Schneider, T.1    Przewlocki, R.2
  • 130
    • 62149085091 scopus 로고    scopus 로고
    • Functional proteomics identify cornichon proteins as auxiliary subunits of AMPA receptors
    • Schwenk J, Harmel N, Zolles G, Bildl W, Kulik A, et al. 2009. Functional proteomics identify cornichon proteins as auxiliary subunits of AMPA receptors. Science 323:1313-19
    • (2009) Science , vol.323 , pp. 1313-1319
    • Schwenk, J.1    Harmel, N.2    Zolles, G.3    Bildl, W.4    Kulik, A.5
  • 131
    • 0016592484 scopus 로고
    • Antipsychotic drugs: Direct correlation between clinical potency and presynaptic action on dopamine neurons
    • Seeman P, Lee T. 1975. Antipsychotic drugs: direct correlation between clinical potency and presynaptic action on dopamine neurons. Science 188:1217-19
    • (1975) Science , vol.188 , pp. 1217-1219
    • Seeman, P.1    Lee, T.2
  • 132
    • 70349792000 scopus 로고    scopus 로고
    • MHC class I: An unexpected role in neuronal plasticity
    • Shatz CJ. 2009. MHC class I: An unexpected role in neuronal plasticity. Neuron 64:40-45
    • (2009) Neuron , vol.64 , pp. 40-45
    • Shatz, C.J.1
  • 133
    • 84887627330 scopus 로고    scopus 로고
    • SHANK3 and IGF1 restore synaptic deficits in neurons from 22q13 deletion syndrome patients
    • Shcheglovitov A, Shcheglovitova O, Yazawa M, Portmann T, Shu R, et al. 2013. SHANK3 and IGF1 restore synaptic deficits in neurons from 22q13 deletion syndrome patients. Nature 503:267-71
    • (2013) Nature , vol.503 , pp. 267-271
    • Shcheglovitov, A.1    Shcheglovitova, O.2    Yazawa, M.3    Portmann, T.4    Shu, R.5
  • 134
    • 0028219211 scopus 로고
    • Changing subunit composition of heteromeric NMDA receptors during development of rat cortex
    • Sheng M, Cummings J, Roldan LA, Jan YN, Jan LY. 1994. Changing subunit composition of heteromeric NMDA receptors during development of rat cortex. Nature 368:144-47
    • (1994) Nature , vol.368 , pp. 144-147
    • Sheng, M.1    Cummings, J.2    Roldan, L.A.3    Jan, Y.N.4    Jan, L.Y.5
  • 135
    • 38149016966 scopus 로고    scopus 로고
    • The cell biology of synaptic plasticity: AMPA receptor trafficking
    • Shepherd JD, Huganir RL. 2007. The cell biology of synaptic plasticity: AMPA receptor trafficking. Annu. Rev. Cell Dev. Biol. 23:613-43
    • (2007) Annu. Rev. Cell Dev. Biol. , vol.23 , pp. 613-643
    • Shepherd, J.D.1    Huganir, R.L.2
  • 136
    • 33750503402 scopus 로고    scopus 로고
    • Arc/Arg3. 1 mediates homeostatic synaptic scaling of AMPA receptors
    • Shepherd JD, Rumbaugh G, Wu J, Chowdhury S, Plath N, et al. 2006. Arc/Arg3. 1 mediates homeostatic synaptic scaling of AMPA receptors. Neuron 52:475-84
    • (2006) Neuron , vol.52 , pp. 475-484
    • Shepherd, J.D.1    Rumbaugh, G.2    Wu, J.3    Chowdhury, S.4    Plath, N.5
  • 137
    • 84875850679 scopus 로고    scopus 로고
    • Fragile X mental retardation protein and synaptic plasticity
    • Sidorov MS, Auerbach BD, BearMF. 2013. Fragile X mental retardation protein and synaptic plasticity. Mol. Brain 6:15
    • (2013) Mol. Brain , vol.6 , pp. 15
    • Sidorov, M.S.1    Auerbach, B.D.2    Bear, M.F.3
  • 138
    • 80053626726 scopus 로고    scopus 로고
    • Increased gene dosage of Ube3a results in autism traits and decreased glutamate synaptic transmission in mice
    • Smith SEP, Zhou YD, Zhang G, Jin Z, Stoppel DC, Anderson MP. 2011. Increased gene dosage of Ube3a results in autism traits and decreased glutamate synaptic transmission in mice. Sci. Transl. Med. 3:103ra97
    • (2011) Sci. Transl. Med. , vol.3 , pp. 103ra97
    • Smith, S.E.P.1    Zhou, Y.D.2    Zhang, G.3    Jin, Z.4    Stoppel, D.C.5    Anderson, M.P.6
  • 139
    • 84878743755 scopus 로고    scopus 로고
    • Prospective investigation of autism and genotype-phenotype correlations in 22q13 deletion syndrome and SHANK3 deficiency
    • Soorya L, Kolevzon A, Zweifach J, Lim T, Dobry Y, et al. 2013. Prospective investigation of autism and genotype-phenotype correlations in 22q13 deletion syndrome and SHANK3 deficiency. Mol. Autism 4:18
    • (2013) Mol. Autism , vol.4 , pp. 18
    • Soorya, L.1    Kolevzon, A.2    Zweifach, J.3    Lim, T.4    Dobry, Y.5
  • 140
    • 84901369071 scopus 로고    scopus 로고
    • Glutamate receptor mutations in psychiatric and neurodevelopmental disorders
    • Soto D, Altafaj X, Sindreu C, Bayes A. 2014. Glutamate receptor mutations in psychiatric and neurodevelopmental disorders. Commun. Integr. Biol. 7:e27887
    • (2014) Commun. Integr. Biol. , vol.7 , pp. e27887
    • Soto, D.1    Altafaj, X.2    Sindreu, C.3    Bayes, A.4
  • 141
    • 79951567150 scopus 로고    scopus 로고
    • Modifying behavioral phenotypes in Fmr1KO mice: Genetic background differences reveal autistic-like responses
    • Spencer CM, Alekseyenko O, Hamilton SM, Thomas AM, Serysheva E, et al. 2011. Modifying behavioral phenotypes in Fmr1KO mice: genetic background differences reveal autistic-like responses. Autism Res. 4:40-56
    • (2011) Autism Res. , vol.4 , pp. 40-56
    • Spencer, C.M.1    Alekseyenko, O.2    Hamilton, S.M.3    Thomas, A.M.4    Serysheva, E.5
  • 142
    • 84909602568 scopus 로고    scopus 로고
    • Intellectual disability and autism spectrum disorders: Causal genes and molecular mechanisms
    • Srivastava AK, Schwartz CE. 2014. Intellectual disability and autism spectrum disorders: causal genes and molecular mechanisms. Neurosci. Biobehav. Rev. 46:161-74
    • (2014) Neurosci. Biobehav. Rev. , vol.46 , pp. 161-174
    • Srivastava, A.K.1    Schwartz, C.E.2
  • 143
    • 80051549592 scopus 로고    scopus 로고
    • Transcript catalogs of human chromosome 21 and orthologous chimpanzee and mouse regions
    • Sturgeon X, Gardiner KJ. 2011. Transcript catalogs of human chromosome 21 and orthologous chimpanzee and mouse regions. Mamm. Genome 22:261-71
    • (2011) Mamm. Genome , vol.22 , pp. 261-271
    • Sturgeon, X.1    Gardiner, K.J.2
  • 144
    • 54049091941 scopus 로고    scopus 로고
    • Neuroligins and neurexins link synaptic function to cognitive disease
    • Sudhof TC. 2008. Neuroligins and neurexins link synaptic function to cognitive disease. Nature 455:903-11
    • (2008) Nature , vol.455 , pp. 903-911
    • Sudhof, T.C.1
  • 145
    • 84886998869 scopus 로고    scopus 로고
    • Neurotransmitter release: The last millisecond in the life of a synaptic vesicle
    • Sudhof TC. 2013. Neurotransmitter release: the last millisecond in the life of a synaptic vesicle. Neuron 80:675-90
    • (2013) Neuron , vol.80 , pp. 675-690
    • Sudhof, T.C.1
  • 146
    • 84884646052 scopus 로고    scopus 로고
    • Questions about DISC1 as a genetic risk factor for schizophrenia
    • Sullivan PF. 2013. Questions about DISC1 as a genetic risk factor for schizophrenia. Mol. Psychiatry 18:1050-52
    • (2013) Mol. Psychiatry , vol.18 , pp. 1050-1052
    • Sullivan, P.F.1
  • 147
    • 0031720755 scopus 로고    scopus 로고
    • Using an animal model of deficient sensorimotor gating to study the pathophysiology and new treatments of schizophrenia
    • Swerdlow NR, GeyerMA. 1998. Using an animal model of deficient sensorimotor gating to study the pathophysiology and new treatments of schizophrenia. Schizophr. Bull. 24:285-301
    • (1998) Schizophr. Bull. , vol.24 , pp. 285-301
    • Swerdlow, N.R.1    Geyer, M.A.2
  • 148
    • 84907987626 scopus 로고    scopus 로고
    • Loss of mTOR-dependent macroautophagy causes autistic-like synaptic pruning deficits
    • Tang G, Gudsnuk K, Kuo S-H, Cotrina Marisa L, Rosoklija G, et al. 2014. Loss of mTOR-dependent macroautophagy causes autistic-like synaptic pruning deficits. Neuron 83:1131-43
    • (2014) Neuron , vol.83 , pp. 1131-1143
    • Tang, G.1    Gudsnuk, K.2    Kuo, S.-H.3    Cotrina Marisa, L.4    Rosoklija, G.5
  • 149
    • 81555218550 scopus 로고    scopus 로고
    • Rare mutations in N-methyl-D-aspartate glutamate receptors in autism spectrum disorders and schizophrenia
    • Tarabeux J, Kebir O, Gauthier J, Hamdan FF, Xiong L, et al. 2011. Rare mutations in N-methyl-D-aspartate glutamate receptors in autism spectrum disorders and schizophrenia. Transl. Psychiatry 1:e55
    • (2011) Transl. Psychiatry , vol.1 , pp. e55
    • Tarabeux, J.1    Kebir, O.2    Gauthier, J.3    Hamdan, F.F.4    Xiong, L.5
  • 150
    • 40849104800 scopus 로고    scopus 로고
    • An essential role for PICK1 in NMDA receptor-dependent bidirectional synaptic plasticity
    • Terashima A, Pelkey KA, Rah JC, Suh YH, Roche KW, et al. 2008. An essential role for PICK1 in NMDA receptor-dependent bidirectional synaptic plasticity. Neuron 57:872-82
    • (2008) Neuron , vol.57 , pp. 872-882
    • Terashima, A.1    Pelkey, K.A.2    Rah, J.C.3    Suh, Y.H.4    Roche, K.W.5
  • 151
    • 0030041171 scopus 로고    scopus 로고
    • A review ofNMDAreceptors and the phencyclidinemodel of schizophrenia
    • Thornberg SA, Saklad SR. 1996. A review ofNMDAreceptors and the phencyclidinemodel of schizophrenia. Pharmacotherapy 16:82-93
    • (1996) Pharmacotherapy , vol.16 , pp. 82-93
    • Thornberg, S.A.1    Saklad, S.R.2
  • 152
    • 33845348602 scopus 로고    scopus 로고
    • Munc18-1 expression levels control synapse recovery by regulating readily releasable pool size
    • Toonen RFG, Wierda K, Sons MS, deWit H, Cornelisse LN, et al. 2006. Munc18-1 expression levels control synapse recovery by regulating readily releasable pool size. PNAS 103:18332-37
    • (2006) PNAS , vol.103 , pp. 18332-18337
    • Toonen, R.F.G.1    Wierda, K.2    Sons, M.S.3    Dewit, H.4    Cornelisse, L.N.5
  • 153
    • 28244433460 scopus 로고    scopus 로고
    • NMDA receptor subunit NRI and postsynaptic protein PSD-95 in hippocampus and orbitofrontal cortex in schizophrenia and mood disorder
    • Toro C, Deakin JF. 2005. NMDA receptor subunit NRI and postsynaptic protein PSD-95 in hippocampus and orbitofrontal cortex in schizophrenia and mood disorder. Schizophr. Res. 80:323-30
    • (2005) Schizophr. Res. , vol.80 , pp. 323-330
    • Toro, C.1    Deakin, J.F.2
  • 156
    • 84865508373 scopus 로고    scopus 로고
    • Autistic-like behaviour and cerebellar dysfunction in Purkinje cell Tsc1 mutant mice
    • Tsai PT, Hull C, Chu Y, Greene-Colozzi E, Sadowski AR, et al. 2012. Autistic-like behaviour and cerebellar dysfunction in Purkinje cell Tsc1 mutant mice. Nature 488:647-51
    • (2012) Nature , vol.488 , pp. 647-651
    • Tsai, P.T.1    Hull, C.2    Chu, Y.3    Greene-Colozzi, E.4    Sadowski, A.R.5
  • 157
    • 0033166537 scopus 로고    scopus 로고
    • Coupling of mGluR/Homer and PSD-95 complexes by the Shank family of postsynaptic density proteins
    • Tu JC, Xiao B, Naisbitt S, Yuan JP, Petralia RS, et al. 1999. Coupling of mGluR/Homer and PSD-95 complexes by the Shank family of postsynaptic density proteins. Neuron 23:583-92
    • (1999) Neuron , vol.23 , pp. 583-592
    • Tu, J.C.1    Xiao, B.2    Naisbitt, S.3    Yuan, J.P.4    Petralia, R.S.5
  • 159
    • 33750512959 scopus 로고    scopus 로고
    • Arc/Arg3. 1: Linking gene expression to synaptic plasticity and memory
    • Tzingounis AV, Nicoll RA. 2006. Arc/Arg3. 1: linking gene expression to synaptic plasticity and memory. Neuron 52:403-7
    • (2006) Neuron , vol.52 , pp. 403-407
    • Tzingounis, A.V.1    Nicoll, R.A.2
  • 161
    • 80755168331 scopus 로고    scopus 로고
    • Genetic and epigenetic networks in intellectual disabilities
    • van Bokhoven H. 2011. Genetic and epigenetic networks in intellectual disabilities. Annu. Rev. Genet. 45:81-104
    • (2011) Annu. Rev. Genet. , vol.45 , pp. 81-104
    • Van Bokhoven, H.1
  • 162
    • 0034603030 scopus 로고    scopus 로고
    • Synaptic assembly of the brain in the absence of neurotransmitter secretion
    • Verhage M, Maia AS, Plomp JJ, Brussaard AB, Heeroma JH, et al. 2000. Synaptic assembly of the brain in the absence of neurotransmitter secretion. Science 287:864-69
    • (2000) Science , vol.287 , pp. 864-869
    • Verhage, M.1    Maia, A.S.2    Plomp, J.J.3    Brussaard, A.B.4    Heeroma, J.H.5
  • 163
    • 78650720266 scopus 로고    scopus 로고
    • Developmental regulation of protein interacting with C kinase 1 (PICK1) function in hippocampal synaptic plasticity and learning
    • Volk L, Kim CH, Takamiya K, Yu Y, Huganir RL. 2010. Developmental regulation of protein interacting with C kinase 1 (PICK1) function in hippocampal synaptic plasticity and learning. PNAS 107:21784-89
    • (2010) PNAS , vol.107 , pp. 21784-21789
    • Volk, L.1    Kim, C.H.2    Takamiya, K.3    Yu, Y.4    Huganir, R.L.5
  • 164
    • 57049147406 scopus 로고    scopus 로고
    • Contribution of hippocampal and extra-hippocampal NR2B-containing NMDA receptors to performance on spatial learning tasks
    • von Engelhardt J, Doganci B, JensenV, HvalbyO, Göngrich C, et al. 2008. Contribution of hippocampal and extra-hippocampal NR2B-containing NMDA receptors to performance on spatial learning tasks. Neuron 60:846-60
    • (2008) Neuron , vol.60 , pp. 846-860
    • Von Engelhardt, J.1    Doganci, B.2    Jensen, V.3    Hvalby, O.4    Göngrich, C.5
  • 165
    • 84907597997 scopus 로고    scopus 로고
    • Common EIF4E variants modulate risk for autism spectrum disorders in the high-functioning range
    • Waltes R, Gfesser J, Haslinger D, Schneider-Momm K, Biscaldi M, et al. 2014. Common EIF4E variants modulate risk for autism spectrum disorders in the high-functioning range. J. Neural Transm. 121:1107-16
    • (2014) J. Neural Transm. , vol.121 , pp. 1107-1116
    • Waltes, R.1    Gfesser, J.2    Haslinger, D.3    Schneider-Momm, K.4    Biscaldi, M.5
  • 166
    • 83255194576 scopus 로고    scopus 로고
    • A critical role forGluN2B-containingNMDA receptors in cortical development and function
    • Wang CC, Held RG, Chang SC, Yang L, Delpire E, et al. 2011. A critical role forGluN2B-containingNMDA receptors in cortical development and function. Neuron 72:789-805
    • (2011) Neuron , vol.72 , pp. 789-805
    • Wang, C.C.1    Held, R.G.2    Chang, S.C.3    Yang, L.4    Delpire, E.5
  • 167
    • 84877254679 scopus 로고    scopus 로고
    • Loss of sorting nexin 27 contributes to excitatory synaptic dysfunction bymodulating glutamate receptor recycling inDown's syndrome
    • Wang X, Zhao Y, Zhang X, Badie H, Zhou Y, et al. 2013. Loss of sorting nexin 27 contributes to excitatory synaptic dysfunction bymodulating glutamate receptor recycling inDown's syndrome. Nat. Med. 19:473-80
    • (2013) Nat. Med. , vol.19 , pp. 473-480
    • Wang, X.1    Zhao, Y.2    Zhang, X.3    Badie, H.4    Zhou, Y.5
  • 168
    • 43949112985 scopus 로고    scopus 로고
    • Mice lacking the AMPA GluR1 receptor exhibit striatal hyperdopaminergia and 'schizophrenia-related' behaviors
    • Wiedholz LM, Owens WA, Horton RE, Feyder M, Karlsson RM, et al. 2008. Mice lacking the AMPA GluR1 receptor exhibit striatal hyperdopaminergia and 'schizophrenia-related' behaviors. Mol. Psychiatry 13:631-40
    • (2008) Mol. Psychiatry , vol.13 , pp. 631-640
    • Wiedholz, L.M.1    Owens, W.A.2    Horton, R.E.3    Feyder, M.4    Karlsson, R.M.5
  • 169
    • 84937436750 scopus 로고    scopus 로고
    • IL1RAPL1 knockout mice show spine density decrease, learning deficiency, hyperactivity and reduced anxiety-like behaviours
    • Yasumura M, Yoshida T, YamazakiM, Abe M, Natsume R, et al. 2014. IL1RAPL1 knockout mice show spine density decrease, learning deficiency, hyperactivity and reduced anxiety-like behaviours. Sci. Rep. 4:6613
    • (2014) Sci. Rep. , vol.4 , pp. 6613
    • Yasumura, M.1    Yoshida, T.2    Yamazaki, M.3    Abe, M.4    Natsume, R.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.