Multiple risk pathways for schizophrenia converge in serine racemase knockout mice, a mouse model of NMDA receptor hypofunction

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 26, 2013, Pages

  Balu, Darrick T ^a,b   Li, Yan ^a   Puhl, Matthew D ^a,b   Benneyworth, Michael A ^a,b   Basu, Alo C ^a,b   Takagi, Shunsuke ^c   Bolshakov, Vadim Y ^a   Coyle, Joseph T ^a,b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b MCLEAN HOSPITAL   (United States)

^c TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

Author keywords

CREB; Glycogen synthase 3 kinase; MeCP2; miR 132

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; DEXTRO SERINE; MAMMALIAN TARGET OF RAPAMYCIN; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PROTEIN KINASE B; RACEMASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN SIZE; CONTROLLED STUDY; DENDRITIC SPINE; DENTATE GYRUS; EXCITATORY POSTSYNAPTIC POTENTIAL; GRANULE CELL; HIPPOCAMPUS; LONG TERM POTENTIATION; MALE; MEMORY; MOUSE; NERVE CELL PLASTICITY; NONHUMAN; PERFORANT NERVE TRACT; PRIORITY JOURNAL; PROTEIN DEFECT; PROTEIN FUNCTION; RISK FACTOR; SCHIZOPHRENIA;

CREB; GLYCOGEN SYNTHASE 3 KINASE; MECP2; MIR-132;

ANIMALS; BRAIN-DERIVED NEUROTROPHIC FACTOR; COGNITION DISORDERS; DENDRITIC SPINES; DISEASE MODELS, ANIMAL; EXCITATORY POSTSYNAPTIC POTENTIALS; HUMANS; LONG-TERM POTENTIATION; MALE; MICE; MICE, KNOCKOUT; MICRORNAS; NEURONAL PLASTICITY; RACEMASES AND EPIMERASES; RECEPTOR, TRKB; RECEPTORS, N-METHYL-D-ASPARTATE; RISK FACTORS; SCHIZOPHRENIA; SERINE; SIGNAL TRANSDUCTION;

MUS;

EID: 84879518895     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1304308110     Document Type: Article

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