The Rho-linked mental retardation protein oligophrenin-1 controls synapse maturation and plasticity by stabilizing AMPA receptors

Genes and Development

Volumn 23, Issue 11, 2009, Pages 1289-1302

  Kasri, Nael Nadif ^a   Nakano Kobayashi, Akiko ^a   Malinow, Roberto ^a,b   Li, Bo ^a   Van Aelst, Linda ^a  

^a Howard Hughes Medical Institute Cold Spring Harbor Laboratory Cold Spring Harbor   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Actin cytoskeleton; AMPA receptor; Glutamatergic function; Mental retardation; Oligophrenin 1; Rho GTPase activating protein

Indexed keywords

AMPA RECEPTOR; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; OLIGOPHRENIN 1; REGULATOR PROTEIN; RHO FACTOR; UNCLASSIFIED DRUG; AMINO ACID RECEPTOR STIMULATING AGENT; CYTOSKELETON PROTEIN; GLUTAMATE RECEPTOR IONOTROPIC, AMPA 2; N METHYLASPARTIC ACID; NUCLEAR PROTEIN; OPHN1 PROTEIN, RAT;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DENDRITIC SPINE; GENE; LOSS OF FUNCTION MUTATION; NERVE CELL PLASTICITY; NONHUMAN; OLIGOPHRENIN 1 GENE; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; RAT; SIGNAL TRANSDUCTION; SYNAPSE; SYNAPTIC TRANSMISSION; X LINKED MENTAL RETARDATION; ANIMAL; CYTOLOGY; DRUG EFFECT; ENDOCYTOSIS; GENE EXPRESSION REGULATION; GROWTH, DEVELOPMENT AND AGING; HIPPOCAMPUS; MENTAL DEFICIENCY; METABOLISM; NERVE CELL; PATHOPHYSIOLOGY; PHYSIOLOGY; PROTEIN TRANSPORT;

ANIMALS; CYTOSKELETAL PROTEINS; ENDOCYTOSIS; EXCITATORY AMINO ACID AGONISTS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GTPASE-ACTIVATING PROTEINS; HIPPOCAMPUS; MENTAL RETARDATION; N-METHYLASPARTATE; NEURONS; NUCLEAR PROTEINS; PROTEIN TRANSPORT; RATS; RECEPTORS, AMPA; SYNAPSES;

EID: 66149180800     PISSN: 08909369     EISSN: 15495477     Source Type: Journal    
DOI: 10.1101/gad.1783809     Document Type: Article

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