Pathogenic SYNGAP1 mutations impair cognitive development by disrupting maturation of dendritic spine synapses

Cell

Volumn 151, Issue 4, 2012, Pages 709-723

  Clement, James P ^a   Aceti, Massimiliano ^a   Creson, Thomas K ^a   Ozkan, Emin D ^a   Shi, Yulin ^b   Reish, Nicholas J ^c   Almonte, Antoine G ^c   Miller, Brooke H ^a   Wiltgen, Brian J ^d   Miller, Courtney A ^a   Xu, Xiangmin ^b   Rumbaugh, Gavin ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c University of Alabama at Birmingham   (United States)

^d UNIVERSITY OF VIRGINIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULTHOOD; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTISM; BEHAVIOR DISORDER; CELL DISRUPTION; CELL MATURATION; COGNITIVE DEVELOPMENT; CONTROLLED STUDY; DENDRITIC SPINE; FEMALE; GENE; GENE MUTATION; HIPPOCAMPUS; INTELLECTUAL IMPAIRMENT; MALE; MOUSE; NERVE EXCITABILITY; NONHUMAN; PERINATAL PERIOD; PRIORITY JOURNAL; SYNAPSE; SYNGAP1 GENE;

EID: 84869038551     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2012.08.045     Document Type: Article

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