NMDA receptor subunit NRI and postsynaptic protein PSD-95 in hippocampus and orbitofrontal cortex in schizophrenia and mood disorder

Schizophrenia Research

Volumn 80, Issue 2-3, 2005, Pages 323-330

  Toro, Carla ^a   Deakin, J F W ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

Glutamate synapse; Post mortem; Schizophrenia

Indexed keywords

MOOD STABILIZER; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 1; NEUROLEPTIC AGENT; POSTSYNAPTIC DENSITY PROTEIN 95;

ADULT; ARTICLE; ASSOCIATION CORTEX; AUTORADIOGRAPHY; BIPOLAR DISORDER; BRAIN CORTEX; DENTATE GYRUS; FEMALE; GRANULE CELL; HIPPOCAMPUS; HUMAN; HUMAN TISSUE; MAJOR DEPRESSION; MALE; MOOD DISORDER; MOSSY FIBER; OPTICAL DENSITY; ORBITAL CORTEX; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR DOWN REGULATION; SCHIZOPHRENIA; SENSORY NERVE; SUBICULUM; SYNAPSE;

ADULT; AUTORADIOGRAPHY; FEMALE; HIPPOCAMPUS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MEMBRANE PROTEINS; MIDDLE AGED; MOOD DISORDERS; NERVE TISSUE PROTEINS; PREFRONTAL CORTEX; RECEPTORS, N-METHYL-D-ASPARTATE; SCHIZOPHRENIA;

EID: 28244433460     PISSN: 09209964     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.schres.2005.07.003     Document Type: Article

References (38)

1. American Psychiatric Association Diagnostic and Statistical Manual of Mental Disorders IV 4th edition 1994 American Psychiatric Publishing Inc. Washington, DC
2. N.C. Andreasen, D.S. O'Leary, M. Flaum, P. Nopoulos, G.L. Watkins, L.L. Boles Ponto, and R.D. Hichwa Hypofrontality in schizophrenia: distributed dysfunctional circuits in neuroleptic-naïve patients Lancet 349 1997 1730 1734
3. W. Berrettini Bipolar disorder and schizophrenia: convergent molecular data Neuromolecular Med. 5 2004 109 117
4. S.M. Clinton, and J.H. Meador-Woodruff Abnormalities of the NMDA receptor and associated intracellular molecules in the thalamus in schizophrenia and bipolar disorder Neuropsychopharmacology 29 2004 1353 1362
5. F. Conti, P. Barbaresi, M. Melone, and A. Ducati Neuronal and glial localization of NR1 and NR2A/B subunits of the NMDA receptor in the human cerebral cortex Cereb. Cortex 9 1999 110 120
6. J.R. Cottrell, E. Borok, T.L. Horvath, and E. Nedivi CPG2: a brain- and synapse-specific protein that regulates the endocytosis of glutamate receptors Neuron 44 2004 677 690
7. J.F. Deakin, P. Slater, M.D. Simpson, A.C. Gilchrist, W.J. Skan, M.C. Royston, G.P. Reynolds, and A.J. Cross Frontal cortical and left temporal glutamatergic dysfunction in schizophrenia J. Neurochem. 52 1989 1781 1786
8. R. Dingledine, K. Borges, D. Bowie, and S.F. Traynelis The glutamate receptor ion channels Pharmacol. Rev. 51 1999 7 61
9. S. Dracheva, S.A. Marras, S.L. Elhakem, F.R. Kramer, K.L. Davis, and V. Haroutunian N-methyl-D-aspartic acid receptor expression in the dorsolateral prefrontal cortex of elderly patients with schizophrenia Am. J. Psychiatry 158 2001 1400 1410
10. W.C. Drevets, J.L. Price, J.R. Simpson Jr., R.D. Todd, T. Reich, M. Vannier, and M.E. Raichle Subgenual prefrontal cortex abnormalities in mood disorders Nature 386 1997 824 827
11. M.A. Fauman, and B.J. Fauman The psychiatric aspects of chronic phencyclidine use: a study of chronic PCP users NIDA Res. Monogr. 1978 183 200
12. X.M. Gao, K. Sakai, R.C. Roberts, R.R. Conley, B. Dean, and C.A. Tamminga Ionotropic glutamate receptors and expression of N-methyl-D-aspartate receptor subunits in subregions of human hippocampus: effects of schizophrenia Am. J. Psychiatry 157 2000 1141 1149
13. D.C. Goff, and J.T. Coyle The emerging role of glutamate in the pathophysiology and treatment of schizophrenia Am. J. Psychiatry 158 2001 1367 1377
14. R.E. Gur, P.E. Cowell, A. Latshaw, B.I. Turetsky, R.I. Grossman, S.E. Arnold, W.B. Bilker, and R.C. Gur Reduced dorsal and orbital prefrontal gray matter volumes in schizophrenia Arch. Gen. Psychiatry 57 2000 761 768
15. P.J. Harrison, and D.R. Weinberger Schizophrenia genes, gene expression, and neuropathology: on the matter of their convergence Mol. Psychiatry 10 2005 40 68
16. H. Husi, M.A. Ward, J.S. Choudhary, W.P. Blackstock, and S.G. Grant Proteomic analysis of NMDA receptor-adhesion protein signaling complexes Nat. Neurosci. 3 2000 661 669
17. M. Ishimaru, A. Kurumaji, and M. Toru Increases in strychnine-insensitive glycine binding sites in cerebral cortex of chronic schizophrenics: evidence for glutamate hypothesis Biol. Psychiatry 35 1994 84 95
18. E. Kim, and M. Sheng PDZ domain proteins of synapses Nat. Rev. Neurosci. 5 2004 771 781
19. J.S. Kim, H.H. Kornhuber, W. Schmid-Burgk, and B. Holzmuller Low cerebrospinal fluid glutamate in schizophrenic patients and a new hypothesis on schizophrenia Neurosci. Lett. 20 1980 379 382
20. N.S. Kolomeets, D.D. Orlovskaya, V.I. Rachmanova, and N.A. Uranova Ultrastructural alterations in hippocampal mossy fiber synapses in schizophrenia: a postmortem morphometric study Synapse 57 2005 47 55
21. H.C. Kornau, L.T. Schenker, M.B. Kennedy, and P.H. Seeburg Domain interaction between NMDA receptor subunits and the postsynaptic density protein PSD-95 Science 269 1995 1737 1740
22. J. Kornhuber, F. Mack-Burkhardt, P. Riederer, G.F. Hebenstreit, G.P. Reynolds, H.B. Andrews, and H. Beckmann [3H]MK-801 binding sites in postmortem brain regions of schizophrenic patients J. Neural Transm. 77 1989 231 236
23. A.C. Lahti, B. Koffel, D. LaPorte, and C.A. Tamminga Subanesthetic doses of ketamine stimulate psychosis in schizophrenia Neuropsychopharmacology 13 1995 9 19
24. A.J. Law, and J.F. Deakin Asymmetrical reductions of hippocampal NMDAR1 glutamate receptor mRNA in the psychoses Neuroreport 12 2001 2971 2974
25. A.J. Law, C.S. Weickert, T.M. Hyde, J.E. Kleinman, and P.J. Harrison Reduced spinophilin but not microtubule-associated protein 2 expression in the hippocampal formation in schizophrenia and mood disorders: molecular evidence for a pathology of dendritic spines Am. J. Psychiatry 161 2004 1848 1855
26. J.H. Meador-Woodruff, V. Haroutunian, P. Powchik, M. Davidson, K.L. Davis, and S.J. Watson Dopamine receptor transcript expression in striatum and prefrontal and occipital cortex. Focal abnormalities in orbitofrontal cortex in schizophrenia Arch. Gen. Psychiatry 54 1997 1089 1095
27. M. Migaud, P. Charlesworth, M. Dempster, L.C. Webster, A.M. Watabe, M. Makhinson, Y. He, M.F. Ramsay, R.G. Morris, J.H. Morrison, T.J. O'Dell, and S.G. Grant Enhanced long-term potentiation and impaired learning in mice with mutant postsynaptic density-95 protein Nature 396 1998 433 439
28. H.T. Mueller, V. Haroutunian, K.L. Davis, and J.H. Meador-Woodruff Expression of the ionotropic glutamate receptor subunits and NMDA receptor-associated intracellular proteins in the substantia nigra in schizophrenia Brain Res. Mol. Brain Res. 121 2004 60 69
29. T. Ohnuma, S.J. Augood, H. Arai, P.J. McKenna, and P.C. Emson Expression of the human excitatory amino acid transporter 2 and metabotropic glutamate receptors 3 and 5 in the prefrontal cortex from normal individuals and patients with schizophrenia Brain Res. Mol. Brain Res. 56 1998 207 217
30. T. Ohnuma, H. Kato, H. Arai, R.L. Faull, P.J. McKenna, and P.C. Emson Gene expression of PSD95 in prefrontal cortex and hippocampus in schizophrenia Neuroreport 11 2000 3133 3137
31. J.W. Olney, and N.B. Farber Glutamate receptor dysfunction and schizophrenia Arch. Gen. Psychiatry 52 1995 998 1007
32. G.W. Roberts, P.N. Leigh, and D.R. Weinberger Neuropsychiatric Disorders 1993 Wolfe Publishing Oxford
33. M. Sheng, and D.T. Pak Ligand-gated ion channel interactions with cytoskeletal and signaling proteins Annu. Rev. Physiol. 62 2000 755 778
34. M.D. Simpson, P. Slater, M.C. Royston, and J.F. Deakin Alterations in phencyclidine and sigma binding sites in schizophrenic brains. Effects of disease process and neuroleptic medication Schizophr. Res. 6 1991 41 48
35. M.D. Simpson, D.I. Lubman, P. Slater, and J.F. Deakin Autoradiography with [3H]8-OH-DPAT reveals increases in 5-HT(1A) receptors in ventral prefrontal cortex in schizophrenia Biol. Psychiatry 39 1996 919 928
36. P.M. Thompson, S. Egbufoama, and M.P. Vawter SNAP-25 reduction in the hippocampus of patients with schizophrenia Prog. Neuro-Psychopharmacol. Biol. Psychiatry 27 2003 411 417
37. E.F. Torrey, M. Webster, M. Knable, N. Johnston, and R.H. Yolken The Stanley foundation brain collection and neuropathology consortium Schizophr. Res. 44 2000 151 155
38. K. Toyooka, S. Iritani, T. Makifuchi, O. Shirakawa, N. Kitamura, K. Maeda, R. Nakamura, K. Niizato, M. Watanabe, A. Kakita, H. Takahashi, T. Someya, and H. Nawa Selective reduction of a PDZ protein, SAP-97, in the prefrontal cortex of patients with chronic schizophrenia J. Neurochem. 83 2002 797 806