Specific involvement of postsynaptic GluN2B-containing NMDA receptors in the developmental elimination of corticospinal synapses

Proceedings of the National Academy of Sciences of the United States of America

Volumn 107, Issue 34, 2010, Pages 15252-15257

  Ohno, Takae ^a   Maeda, Hitoshi ^a   Murabe, Naoyuki ^a   Kamiyama, Tsutomu ^a   Yoshioka, Noboru ^a   Mishina, Masayoshi ^b   Sakurai, Masaki ^a  

^a TEIKYO UNIVERSITY   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

Author keywords

Axon regression; GluN2A (GluR 1 NR2A); GluN2B (GluR 2 NR2B); Synapse elimination

Indexed keywords

N METHYL DEXTRO ASPARTIC ACID RECEPTOR; YELLOW FLUORESCENT PROTEIN; N METHYL D ASPARTATE RECEPTOR SUBTYPE 2A; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2B; N-METHYL D-ASPARTATE RECEPTOR SUBTYPE 2A;

ANIMAL EXPERIMENT; ARTICLE; BRAIN DEVELOPMENT; BRAIN SLICE; COCULTURE; CONTROLLED STUDY; ELECTRIC POTENTIAL; ELECTROPHYSIOLOGY; ELECTROPORATION; GENOTYPE; MOUSE; NERVE CELL PLASTICITY; NERVE FIBER; NONHUMAN; PRIORITY JOURNAL; PYRAMIDAL TRACT; SYNAPSE; ANIMAL; BRAIN CORTEX; C57BL MOUSE; COMPARATIVE STUDY; EXCITATORY POSTSYNAPTIC POTENTIAL; GENETICS; GROWTH, DEVELOPMENT AND AGING; IN VITRO STUDY; INSTITUTE FOR CANCER RESEARCH MOUSE; MOUSE MUTANT; PHYSIOLOGY; RAT; SPINAL CORD; ULTRASTRUCTURE;

ANIMALIA; MUS; RODENTIA;

ANIMALS; CEREBRAL CORTEX; COCULTURE TECHNIQUES; ELECTROPHYSIOLOGICAL PHENOMENA; EXCITATORY POSTSYNAPTIC POTENTIALS; MICE; MICE, INBRED C57BL; MICE, INBRED ICR; MICE, KNOCKOUT; NEURONAL PLASTICITY; RATS; RECEPTORS, N-METHYL-D-ASPARTATE; SPINAL CORD; SYNAPSES;

EID: 77957012316     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0906551107     Document Type: Article

References (51)

1. Kleinschmidt A, Bear MF, Singer W (1987) Blockade of "NMDA" receptors disrupts experience-dependent plasticity of kitten striate cortex. Science 238:355-358.
2. Cline HT, Constantine-Paton M (1989) NMDA receptor antagonists disrupt the retinotectal topographic map. Neuron 3:413-426.
3. Fox K, Schlaggar BL, Glazewski S, O'Leary DD (1996) Glutamate receptor blockade at cortical synapses disrupts development of thalamocortical and columnar organization in somatosensory cortex. Proc Natl Acad Sci USA 93:5584-5589. (Pubitemid 26159494)
4. Iwasato T, et al. (1997) NMDA receptor-dependent refinement of somatotopic maps. Neuron 19:1201-1210.
5. Sheng M, Cummings J, Roldan LA, Jan YN, Jan LY (1994) Changing subunit composition of heteromeric NMDA receptors during development of rat cortex. Nature 368:144-147.
6. Liu XB, Murray KD, Jones EG (2004) Switching of NMDA receptor 2A and 2B subunits at thalamic and cortical synapses during early postnatal development. J Neurosci 24:8885-8895.
7. Flint AC, Maisch US, Weishaupt JH, Kriegstein AR, Monyer H (1997) NR2A subunit expression shortens NMDA receptor synaptic currents in developing neocortex. J Neurosci 17:2469-2476.
8. Vicini S, et al. (1998) Functional and pharmacological differences between recombinant N-methyl-D-aspartate receptors. J Neurophysiol 79:555-566.
9. Carmignoto G, Vicini S (1992) Activity-dependent decrease in NMDA receptor responses during development of the visual cortex. Science 258:1007-1011.
10. Hestrin S (1992) Developmental regulation of NMDA receptor-mediated synaptic currents at a central synapse. Nature 357:686-689.
11. Erisir A, Harris JL (2003) Decline of the critical period of visual plasticity is concurrent with the reduction of NR2B subunit of the synaptic NMDA receptor in layer 4. J Neurosci 23:5208-5218. (Pubitemid 36793249)
12. Barria A, Malinow R (2005) NMDA receptor subunit composition controls synaptic plasticity by regulating binding to CaMKII. Neuron 48:289-301.
13. Espinosa JS, Wheeler DG, Tsien RW, Luo L (2009) Uncoupling dendrite growth and patterning: Single-cell knockout analysis of NMDA receptor 2B. Neuron 62:205-217.
14. Fagiolini M, et al. (2003) Separable features of visual cortical plasticity revealed by N-methyl-D-aspartate receptor 2A signaling. Proc Natl Acad Sci USA 100:2854-2859.
15. Quinlan EM, Philpot BD, Huganir RL, Bear MF (1999) Rapid, experience-dependent expression of synaptic NMDA receptors in visual cortex in vivo. Nat Neurosci 2:352-357.
16. Roberts EB, Ramoa AS (1999) Enhanced NR2A subunit expression and decreased NMDA receptor decay time at the onset of ocular dominance plasticity in the ferret. J Neurophysiol 81:2587-2591.
17. Heinrich JE, Singh TD, Sohrabji F, Nordeen KW, Nordeen EJ (2002) Developmental and hormonal regulation of NR2A mRNA in forebrain regions controlling avian vocal learning. J Neurobiol 51:149-159. (Pubitemid 34297312)
18. Philpot BD, Cho KK, Bear MF (2007) Obligatory role of NR2A for metaplasticity in visual cortex. Neuron 53:495-502.
19. Lu HC, Gonzalez E, Crair MC (2001) Barrel cortex critical period plasticity is independent of changes in NMDA receptor subunit composition. Neuron 32:619-634.
20. Kutsuwada T, et al. (1996) Impairment of suckling response, trigeminal neuronal pattern formation, and hippocampal LTD in NMDA receptor epsilon 2 subunit mutant mice. Neuron 16:333-344.
21. Takuma H, Sakurai M, Kanazawa I (2002) In vitro formation of corticospinal synapses in an organotypic slice co-culture. Neuroscience 109:359-370.
22. Ohno T, Maeda H, SakuraiM(2004) Regionally specific distribution of corticospinal synapses because of activity-dependent synapse elimination in vitro. J Neurosci 24:1377-1384.
23. Ohno T, Sakurai M (2005) Critical period for activity-dependent elimination of corticospinal synapses in vitro. Neuroscience 132:917-922. (Pubitemid 40602527)
24. Kamiyama T, Yoshioka N, Sakurai M (2006) Synapse elimination in the corticospinal projection during the early postnatal period. J Neurophysiol 95:2304-2313.
25. Martin JH, Friel KM, Salimi I, Chakrabarty S (2009) Developmental Neurobiology, ed Lemke G (Elsevier, Amsterdam), pp 403-414.
26. Maeda H, Ohno T, Sakurai M (2007) Optical and electrophysiological recordings of corticospinal synaptic activity and its developmental change in in vitro rat slice cocultures. Neuroscience 150:829-840.
27. Yamamoto N, Kurotani T, Toyama K (1989) Neural connections between the lateral geniculate nucleus and visual cortex in vitro. Science 245:192-194. (Pubitemid 19193939)
28. Sakimura K, et al. (1995) Reduced hippocampal LTP and spatial learning in mice lacking NMDA receptor epsilon 1 subunit. Nature 373:151-155.
29. Akashi K, et al. (2009) NMDA receptor GluN2B (GluR epsilon 2/NR2B) subunit is crucial for channel function, postsynaptic macromolecular organization, and actin cytoskeleton at hippocampal CA3 synapses. J Neurosci 29:10869-10882.
30. Wong RO (1999) Retinal waves and visual system development. Annu Rev Neurosci 22:29-47.
31. McLaughlin T, Torborg CL, Feller MB, O'Leary DD (2003) Retinotopic map refinement requires spontaneous retinal waves during a brief critical period of development. Neuron 40:1147-1160. (Pubitemid 38032791)
32. Casado M, Isope P, Ascher P (2002) Involvement of presynaptic N-methyl-D-aspartate receptors in cerebellar long-term depression. Neuron 33:123-130.
33. Lien CC, Mu Y, Vargas-Caballero M, Poo MM (2006) Visual stimuli-induced LTD of GABAergic synapses mediated by presynaptic NMDA receptors. Nat Neurosci 9:372-380. (Pubitemid 43290967)
34. Jourdain P, et al. (2007) Glutamate exocytosis from astrocytes controls synaptic strength. Nat Neurosci 10:331-339.
35. Saito T, Nakatsuji N (2001) Efficient gene transfer into the embryonic mouse brain using in vivo electroporation. Dev Biol 240:237-246. (Pubitemid 33141120)
36. Saito T (2006) In vivo electroporation in the embryonic mouse central nervous system. Nat Protoc 1:1552-1558.
37. Yoshimura Y, Ohmura T, Komatsu Y (2003) Two forms of synaptic plasticity with distinct dependence on age, experience, and NMDA receptor subtype in rat visual cortex. J Neurosci 23:6557-6566.
38. Liu L, et al. (2004) Role of NMDA receptor subtypes in governing the direction of hippocampal synaptic plasticity. Science 304:1021-1024.
39. Hall BJ, Ripley B, Ghosh A (2007) NR2B signaling regulates the development of synaptic AMPA receptor current. J Neurosci 27:13446-13456. (Pubitemid 350255329)
40. Hrabetova S, et al. (2000) Distinct NMDA receptor subpopulations contribute to long-term potentiation and long-term depression induction. J Neurosci 20:RC81.
41. Massey PV, et al. (2004) Differential roles of NR2A and NR2B-containing NMDA receptors in cortical long-term potentiation and long-term depression. J Neurosci 24:7821-7828.
42. 2+ channel-dependent long-term depression in the juvenile superior colliculus. J Neurosci 27:13649-13654.
43. Berberich S, et al. (2005) Lack of NMDA receptor subtype selectivity for hippocampal long-term potentiation. J Neurosci 25:6907-6910.
44. Morishita W, et al. (2007) Activation of NR2B-containing NMDA receptors is not required for NMDA receptor-dependent long-term depression. Neuropharmacology 52:71-76.
45. Artola A, Bröcher S, Singer W (1990) Different voltage-dependent thresholds for inducing long-term depression and long-term potentiation in slices of rat visual cortex. Nature 347:69-72. (Pubitemid 20280181)
46. Lisman J (1989) A mechanism for the Hebb and the anti-Hebb processes underlying learning and memory. Proc Natl Acad Sci USA 86:9574-9578.
47. Mizuno T, Kanazawa I, Sakurai M (2001) Differential induction of LTP and LTD is not determined solely by instantaneous calcium concentration: An essential involvement of a temporal factor. Eur J Neurosci 14:701-708.
48. Sheng M, Kim MJ (2002) Postsynaptic signaling and plasticity mechanisms. Science 298:776-780.
49. Sans N, et al. (2000) A developmental change in NMDA receptor-associated proteins at hippocampal synapses. J Neurosci 20:1260-1271.
50. Yoshii A, Sheng MH, Constantine-Paton M (2003) Eye opening induces a rapid dendritic localization of PSD-95 in central visual neurons. Proc Natl Acad Sci USA 100:1334-1339. (Pubitemid 36184002)
51. Barth AL, Malenka RC (2001) NMDAR EPSC kinetics do not regulate the critical period for LTP at thalamocortical synapses. Nat Neurosci 4:235-236.