메뉴 건너뛰기




Volumn 8, Issue 2, 2014, Pages 338-346

Neurexin Dysfunction in Adult Neurons Results in Autistic-like Behavior in Mice

Author keywords

[No Author keywords available]

Indexed keywords

GLUTAMIC ACID; MUTANT PROTEIN; NEUREXIN; NEUREXIN 1BETA; UNCLASSIFIED DRUG;

EID: 84904731433     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2014.06.022     Document Type: Article
Times cited : (66)

References (48)
  • 2
    • 26944444692 scopus 로고    scopus 로고
    • A splice code for trans-synaptic cell adhesion mediated by binding of neuroligin 1 to alpha- and beta-neurexins
    • Boucard A.A., Chubykin A.A., Comoletti D., Taylor P., Südhof T.C. A splice code for trans-synaptic cell adhesion mediated by binding of neuroligin 1 to alpha- and beta-neurexins. Neuron 2005, 48:229-236.
    • (2005) Neuron , vol.48 , pp. 229-236
    • Boucard, A.A.1    Chubykin, A.A.2    Comoletti, D.3    Taylor, P.4    Südhof, T.C.5
  • 3
    • 0032544613 scopus 로고    scopus 로고
    • A tripartite protein complex with the potential to couple synaptic vesicle exocytosis to cell adhesion in brain
    • Butz S., Okamoto M., Südhof T.C. A tripartite protein complex with the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. Cell 1998, 94:773-782.
    • (1998) Cell , vol.94 , pp. 773-782
    • Butz, S.1    Okamoto, M.2    Südhof, T.C.3
  • 5
  • 6
    • 0035093830 scopus 로고    scopus 로고
    • Deficiency of methyl-CpG binding protein-2 in CNS neurons results in a Rett-like phenotype in mice
    • Chen R.Z., Akbarian S., Tudor M., Jaenisch R. Deficiency of methyl-CpG binding protein-2 in CNS neurons results in a Rett-like phenotype in mice. Nat. Genet. 2001, 27:327-331.
    • (2001) Nat. Genet. , vol.27 , pp. 327-331
    • Chen, R.Z.1    Akbarian, S.2    Tudor, M.3    Jaenisch, R.4
  • 8
    • 79955672523 scopus 로고    scopus 로고
    • Neurexin-neuroligin transsynaptic interaction mediates learning-related synaptic remodeling and long-term facilitation in aplysia
    • Choi Y.B., Li H.L., Kassabov S.R., Jin I., Puthanveettil S.V., Karl K.A., Lu Y., Kim J.H., Bailey C.H., Kandel E.R. Neurexin-neuroligin transsynaptic interaction mediates learning-related synaptic remodeling and long-term facilitation in aplysia. Neuron 2011, 70:468-481.
    • (2011) Neuron , vol.70 , pp. 468-481
    • Choi, Y.B.1    Li, H.L.2    Kassabov, S.R.3    Jin, I.4    Puthanveettil, S.V.5    Karl, K.A.6    Lu, Y.7    Kim, J.H.8    Bailey, C.H.9    Kandel, E.R.10
  • 13
    • 70449686185 scopus 로고    scopus 로고
    • Mouse neurexin-1alpha deletion causes correlated electrophysiological and behavioral changes consistent with cognitive impairments
    • Etherton M.R., Blaiss C.A., Powell C.M., Südhof T.C. Mouse neurexin-1alpha deletion causes correlated electrophysiological and behavioral changes consistent with cognitive impairments. Proc. Natl. Acad. Sci. USA 2009, 106:17998-18003.
    • (2009) Proc. Natl. Acad. Sci. USA , vol.106 , pp. 17998-18003
    • Etherton, M.R.1    Blaiss, C.A.2    Powell, C.M.3    Südhof, T.C.4
  • 15
    • 33846564563 scopus 로고    scopus 로고
    • Retrograde modulation of presynaptic release probability through signaling mediated by PSD-95-neuroligin
    • Futai K., Kim M.J., Hashikawa T., Scheiffele P., Sheng M., Hayashi Y. Retrograde modulation of presynaptic release probability through signaling mediated by PSD-95-neuroligin. Nat. Neurosci. 2007, 10:186-195.
    • (2007) Nat. Neurosci. , vol.10 , pp. 186-195
    • Futai, K.1    Kim, M.J.2    Hashikawa, T.3    Scheiffele, P.4    Sheng, M.5    Hayashi, Y.6
  • 18
    • 84883387704 scopus 로고    scopus 로고
    • Membrane-tethered monomeric neurexin LNS-domain triggers synapse formation
    • Gokce O., Südhof T.C. Membrane-tethered monomeric neurexin LNS-domain triggers synapse formation. J.Neurosci. 2013, 33:14617-14628.
    • (2013) J.Neurosci. , vol.33 , pp. 14617-14628
    • Gokce, O.1    Südhof, T.C.2
  • 19
    • 33748576937 scopus 로고    scopus 로고
    • Clathrin-mediated endocytosis is the dominant mechanism of vesicle retrieval at hippocampal synapses
    • Granseth B., Odermatt B., Royle S.J., Lagnado L. Clathrin-mediated endocytosis is the dominant mechanism of vesicle retrieval at hippocampal synapses. Neuron 2006, 51:773-786.
    • (2006) Neuron , vol.51 , pp. 773-786
    • Granseth, B.1    Odermatt, B.2    Royle, S.J.3    Lagnado, L.4
  • 20
    • 84879522237 scopus 로고    scopus 로고
    • Altered social behaviours in neurexin 1α knockout mice resemble core symptoms in neurodevelopmental disorders
    • Grayton H.M., Missler M., Collier D.A., Fernandes C. Altered social behaviours in neurexin 1α knockout mice resemble core symptoms in neurodevelopmental disorders. PLoS ONE 2013, 8:e67114.
    • (2013) PLoS ONE , vol.8
    • Grayton, H.M.1    Missler, M.2    Collier, D.A.3    Fernandes, C.4
  • 21
    • 33847266846 scopus 로고    scopus 로고
    • Reversal of neurological defects in a mouse model of Rett syndrome
    • Guy J., Gan J., Selfridge J., Cobb S., Bird A. Reversal of neurological defects in a mouse model of Rett syndrome. Science 2007, 315:1143-1147.
    • (2007) Science , vol.315 , pp. 1143-1147
    • Guy, J.1    Gan, J.2    Selfridge, J.3    Cobb, S.4    Bird, A.5
  • 25
    • 84862898614 scopus 로고    scopus 로고
    • Activity-dependent regulation of inhibition via GAD67
    • Lau C.G., Murthy V.N. Activity-dependent regulation of inhibition via GAD67. J.Neurosci. 2012, 32:8521-8531.
    • (2012) J.Neurosci. , vol.32 , pp. 8521-8531
    • Lau, C.G.1    Murthy, V.N.2
  • 27
    • 79954589602 scopus 로고    scopus 로고
    • Sensory processing in autism: a review of neurophysiologic findings
    • Marco E.J., Hinkley L.B., Hill S.S., Nagarajan S.S. Sensory processing in autism: a review of neurophysiologic findings. Pediatr. Res. 2011, 69:48R-54R.
    • (2011) Pediatr. Res. , vol.69
    • Marco, E.J.1    Hinkley, L.B.2    Hill, S.S.3    Nagarajan, S.S.4
  • 28
    • 0029807527 scopus 로고    scopus 로고
    • Control of memory formation through regulated expression of a CaMKII transgene
    • Mayford M., Bach M.E., Huang Y.Y., Wang L., Hawkins R.D., Kandel E.R. Control of memory formation through regulated expression of a CaMKII transgene. Science 1996, 274:1678-1683.
    • (1996) Science , vol.274 , pp. 1678-1683
    • Mayford, M.1    Bach, M.E.2    Huang, Y.Y.3    Wang, L.4    Hawkins, R.D.5    Kandel, E.R.6
  • 29
    • 79960075356 scopus 로고    scopus 로고
    • Adult neural function requires MeCP2
    • McGraw C.M., Samaco R.C., Zoghbi H.Y. Adult neural function requires MeCP2. Science 2011, 333:186.
    • (2011) Science , vol.333 , pp. 186
    • McGraw, C.M.1    Samaco, R.C.2    Zoghbi, H.Y.3
  • 31
    • 84889561601 scopus 로고    scopus 로고
    • Integrative functional genomic analyses implicate specific molecular pathways and circuits in autism
    • Parikshak N.N., Luo R., Zhang A., Won H., Lowe J.K., Chandran V., Horvath S., Geschwind D.H. Integrative functional genomic analyses implicate specific molecular pathways and circuits in autism. Cell 2013, 155:1008-1021.
    • (2013) Cell , vol.155 , pp. 1008-1021
    • Parikshak, N.N.1    Luo, R.2    Zhang, A.3    Won, H.4    Lowe, J.K.5    Chandran, V.6    Horvath, S.7    Geschwind, D.H.8
  • 33
    • 0028958250 scopus 로고
    • Neurexins are differentially expressed in the embryonic nervous system of mice
    • Püschel A.W., Betz H. Neurexins are differentially expressed in the embryonic nervous system of mice. J.Neurosci. 1995, 15:2849-2856.
    • (1995) J.Neurosci. , vol.15 , pp. 2849-2856
    • Püschel, A.W.1    Betz, H.2
  • 35
    • 0034625250 scopus 로고    scopus 로고
    • Neuroligin expressed in nonneuronal cells triggers presynaptic development in contacting axons
    • Scheiffele P., Fan J., Choih J., Fetter R., Serafini T. Neuroligin expressed in nonneuronal cells triggers presynaptic development in contacting axons. Cell 2000, 101:657-669.
    • (2000) Cell , vol.101 , pp. 657-669
    • Scheiffele, P.1    Fan, J.2    Choih, J.3    Fetter, R.4    Serafini, T.5
  • 36
    • 84875478700 scopus 로고    scopus 로고
    • Corticostriatal connectivity and its role in disease
    • Shepherd G.M. Corticostriatal connectivity and its role in disease. Nat. Rev. Neurosci. 2013, 14:278-291.
    • (2013) Nat. Rev. Neurosci. , vol.14 , pp. 278-291
    • Shepherd, G.M.1
  • 38
    • 54049091941 scopus 로고    scopus 로고
    • Neuroligins and neurexins link synaptic function to cognitive disease
    • Südhof T.C. Neuroligins and neurexins link synaptic function to cognitive disease. Nature 2008, 455:903-911.
    • (2008) Nature , vol.455 , pp. 903-911
    • Südhof, T.C.1
  • 40
    • 0036270811 scopus 로고    scopus 로고
    • Structure and evolution of neurexingenes: insight into the mechanism of alternative splicing
    • Tabuchi K., Südhof T.C. Structure and evolution of neurexingenes: insight into the mechanism of alternative splicing. Genomics 2002, 79:849-859.
    • (2002) Genomics , vol.79 , pp. 849-859
    • Tabuchi, K.1    Südhof, T.C.2
  • 41
    • 84897528076 scopus 로고    scopus 로고
    • Cartography of neurexin alternative splicing mapped by single-molecule long-read mRNA sequencing
    • Treutlein B., Gokce O., Quake S.R., Südhof T.C. Cartography of neurexin alternative splicing mapped by single-molecule long-read mRNA sequencing. Proc. Natl. Acad. Sci. USA 2014, 111:E1291-E1299.
    • (2014) Proc. Natl. Acad. Sci. USA , vol.111
    • Treutlein, B.1    Gokce, O.2    Quake, S.R.3    Südhof, T.C.4
  • 43
    • 0026769035 scopus 로고
    • Neurexins: synaptic cell surface proteins related to the alpha-latrotoxin receptor and laminin
    • Ushkaryov Y.A., Petrenko A.G., Geppert M., Südhof T.C. Neurexins: synaptic cell surface proteins related to the alpha-latrotoxin receptor and laminin. Science 1992, 257:50-56.
    • (1992) Science , vol.257 , pp. 50-56
    • Ushkaryov, Y.A.1    Petrenko, A.G.2    Geppert, M.3    Südhof, T.C.4
  • 46
    • 84862297282 scopus 로고    scopus 로고
    • Autistic-like social behaviour in Shank2-mutant mice improved by restoring NMDA receptor function
    • Won H., Lee H.R., Gee H.Y., Mah W., Kim J.I., Lee J., Ha S., Chung C., Jung E.S., Cho Y.S., et al. Autistic-like social behaviour in Shank2-mutant mice improved by restoring NMDA receptor function. Nature 2012, 486:261-265.
    • (2012) Nature , vol.486 , pp. 261-265
    • Won, H.1    Lee, H.R.2    Gee, H.Y.3    Mah, W.4    Kim, J.I.5    Lee, J.6    Ha, S.7    Chung, C.8    Jung, E.S.9    Cho, Y.S.10
  • 47
    • 67749118329 scopus 로고    scopus 로고
    • Simple behavioral assessment of mouse olfaction
    • (New York: John Wiley & Sons), Chapter 8, Unit 8.24.
    • Yang, M., and Crawley, J.N. (2009). Simple behavioral assessment of mouse olfaction. Curr. Protoc. Neurosci. (New York: John Wiley & Sons), Chapter 8, Unit 8.24.
    • (2009) Curr. Protoc. Neurosci.
    • Yang, M.1    Crawley, J.N.2
  • 48
    • 84255209293 scopus 로고    scopus 로고
    • Automated three-chambered social approach task for mice
    • (New York: John Wiley & Sons), Chapter 8, Unit 8.26.
    • Yang, M., Silverman, J.L., and Crawley, J.N. (2011). Automated three-chambered social approach task for mice. Curr. Protoc. Neurosci. (New York: John Wiley & Sons), Chapter 8, Unit 8.26.
    • (2011) Curr. Protoc. Neurosci
    • Yang, M.1    Silverman, J.L.2    Crawley, J.N.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.