Autistic-like behaviour and cerebellar dysfunction in Purkinje cell Tsc1 mutant mice

Nature

Volumn 488, Issue 7413, 2012, Pages 647-651

  Tsai, Peter T ^a   Hull, Court ^b   Chu, Yunxiang ^b   Greene Colozzi, Emily ^a   Sadowski, Abbey R ^a   Leech, Jarrett M ^a   Steinberg, Jason ^a   Crawley, Jacqueline N ^c   Regehr, Wade G ^b   Sahin, Mustafa ^a  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MAMMALIAN TARGET OF RAPAMYCIN; RAPAMYCIN;

BRAIN; COGNITION; INJURY; MOLECULAR ANALYSIS; MUTATION; NERVOUS SYSTEM DISORDER; NEUROLOGY; PATHOGENICITY; PATHOLOGY; PROTEIN; RODENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTISM; CEREBELLUM DISEASE; CEREBELLUM INJURY; CONTROLLED STUDY; GENE MUTATION; HETEROZYGOSITY LOSS; HOMOZYGOSITY; HYPERMETABOLISM; MOUSE; NEUROPATHOLOGY; NONHUMAN; PRIORITY JOURNAL; PURKINJE CELL; SIGNAL TRANSDUCTION; TUBEROUS SCLEROSIS;

ANIMALS; AUTISTIC DISORDER; BEHAVIOR, ANIMAL; CELL COUNT; CELL SHAPE; CEREBELLUM; GROOMING; HETEROZYGOTE; MAZE LEARNING; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MUTATION; PURKINJE CELLS; ROTAROD PERFORMANCE TEST; SIROLIMUS; SYNAPSES; TOR SERINE-THREONINE KINASES; TUBEROUS SCLEROSIS; TUMOR SUPPRESSOR PROTEINS; VOCALIZATION, ANIMAL;

MAMMALIA; MUS;

EID: 84865508373     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature11310     Document Type: Article

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