Reduced cortical activity due to a shift in the balance between excitation and inhibition in a mouse model of Rett Syndrome

Proceedings of the National Academy of Sciences of the United States of America

Volumn 102, Issue 35, 2005, Pages 12560-12565

  Dani, Vardhan S ^a   Chang, Qiang ^b   Maffei, Arianna ^a   Turrigiano, Gina G ^a   Jaenisch, Rudolf ^b,c   Nelson, Sacha B ^a  

^a BRANDEIS UNIVERSITY   (United States)

^b WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH   (United States)

^c MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

Autism; Cortical circuit; MeCP2; Mental retardation

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTISM; BRAIN CORTEX; CONTROLLED STUDY; ELECTROPHYSIOLOGY; EXCITATORY POSTSYNAPTIC POTENTIAL; FEMALE; GENE; GENE FUNCTION; GENE MUTATION; INHIBITORY POSTSYNAPTIC POTENTIAL; MALE; MECP2 GENE; MENTAL DEFICIENCY; MOUSE; NERVE CELL INHIBITION; NERVE CELL STIMULATION; NONHUMAN; PATCH CLAMP; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; RETT SYNDROME;

ANIMALS; CEREBRAL CORTEX; CHROMOSOMAL PROTEINS, NON-HISTONE; DISEASE MODELS, ANIMAL; DNA-BINDING PROTEINS; ELECTROPHYSIOLOGY; FEMALE; HUMANS; MALE; METHYL-CPG-BINDING PROTEIN 2; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, MUTANT STRAINS; MUTATION; PATCH-CLAMP TECHNIQUES; PYRAMIDAL CELLS; REPRESSOR PROTEINS; RETT SYNDROME; SYNAPTIC TRANSMISSION;

EID: 24644490120     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0506071102     Document Type: Article

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