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Volumn 87, Issue , 2015, Pages 15-24

Basic biology and therapeutic implications of lncRNA

Author keywords

AntagoNAT; Epigenetic regulation; Imprinting; LincRNA; Natural antisense transcripts; Paraspeckles; Telomeres; VlincRNA

Indexed keywords

CHROMOSOMES; MAMMALS; NUCLEIC ACIDS; PLANTS (BOTANY); RNA;

EID: 84937252794     PISSN: 0169409X     EISSN: 18728294     Source Type: Journal    
DOI: 10.1016/j.addr.2015.05.012     Document Type: Review
Times cited : (287)

References (100)
  • 6
    • 84896725357 scopus 로고    scopus 로고
    • Nuclear lncRNAs as epigenetic regulators-beyond skepticism
    • (PMID: 24200874)
    • Nakagawa S., Kageyama Y. Nuclear lncRNAs as epigenetic regulators-beyond skepticism. Biochim. Biophys. Acta 2014, 1839(3):215-222. (PMID: 24200874).
    • (2014) Biochim. Biophys. Acta , vol.1839 , Issue.3 , pp. 215-222
    • Nakagawa, S.1    Kageyama, Y.2
  • 8
    • 84928761213 scopus 로고    scopus 로고
    • The landscape of long noncoding RNA classification
    • (PMID: 25869999)
    • St Laurent G., Wahlestedt C., Kapranov P. The landscape of long noncoding RNA classification. Trends Genet. 2015, 31(5):239-251. (PMID: 25869999).
    • (2015) Trends Genet. , vol.31 , Issue.5 , pp. 239-251
    • St Laurent, G.1    Wahlestedt, C.2    Kapranov, P.3
  • 10
    • 84879671055 scopus 로고    scopus 로고
    • Pervasive transcription of the human genome produces thousands of previously unidentified long intergenic noncoding RNAs
    • (PMID: 23818866)
    • Hangauer M.J., Vaughn I.W., McManus M.T. Pervasive transcription of the human genome produces thousands of previously unidentified long intergenic noncoding RNAs. PLoS Genet. 2013, 9(6):e1003569. (PMID: 23818866).
    • (2013) PLoS Genet. , vol.9 , Issue.6 , pp. e1003569
    • Hangauer, M.J.1    Vaughn, I.W.2    McManus, M.T.3
  • 11
    • 84880652927 scopus 로고    scopus 로고
    • Targeting long non-coding RNA to therapeutically upregulate gene expression
    • (PMID: 23722346)
    • Wahlestedt C. Targeting long non-coding RNA to therapeutically upregulate gene expression. Nat. Rev. Drug Discov. 2013, 12(6):433-446. (PMID: 23722346).
    • (2013) Nat. Rev. Drug Discov. , vol.12 , Issue.6 , pp. 433-446
    • Wahlestedt, C.1
  • 12
    • 84886071296 scopus 로고    scopus 로고
    • Sense-antisense gene pairs: sequence, transcription, and structure are not conserved between human and mouse
    • (PMID: 24133500)
    • Wood E.J., Chin-Inmanu K., Jia H., Lipovich L. Sense-antisense gene pairs: sequence, transcription, and structure are not conserved between human and mouse. Front. Genet. 2013, 4:183. (PMID: 24133500).
    • (2013) Front. Genet. , vol.4 , pp. 183
    • Wood, E.J.1    Chin-Inmanu, K.2    Jia, H.3    Lipovich, L.4
  • 13
    • 79955468280 scopus 로고    scopus 로고
    • Long non-coding RNA ANRIL is required for the PRC2 recruitment to and silencing of p15(INK4B) tumor suppressor gene
    • (PMID: 21151178)
    • Kotake Y., Nakagawa T., Kitagawa K., Suzuki S., Liu N., Kitagawa M., Xiong Y. Long non-coding RNA ANRIL is required for the PRC2 recruitment to and silencing of p15(INK4B) tumor suppressor gene. Oncogene 2011, 30(16):1956-1962. (PMID: 21151178).
    • (2011) Oncogene , vol.30 , Issue.16 , pp. 1956-1962
    • Kotake, Y.1    Nakagawa, T.2    Kitagawa, K.3    Suzuki, S.4    Liu, N.5    Kitagawa, M.6    Xiong, Y.7
  • 15
    • 84897896279 scopus 로고    scopus 로고
    • The long non-coding RNA Paupar regulates the expression of both local and distal genes
    • (PMID: 24488179)
    • Vance K.W., Sansom S.N., Lee S., Chalei V., Kong L., Cooper S.E., Oliver P.L., Ponting C.P. The long non-coding RNA Paupar regulates the expression of both local and distal genes. EMBO J. 2014, 33(4):296-311. (PMID: 24488179).
    • (2014) EMBO J. , vol.33 , Issue.4 , pp. 296-311
    • Vance, K.W.1    Sansom, S.N.2    Lee, S.3    Chalei, V.4    Kong, L.5    Cooper, S.E.6    Oliver, P.L.7    Ponting, C.P.8
  • 17
    • 84876126629 scopus 로고    scopus 로고
    • Non-coding RNAs at the Gnas and Snrpn-Ube3a imprinted gene loci and their involvement in hereditary disorders
    • (PMID: 23226156)
    • Plagge A. Non-coding RNAs at the Gnas and Snrpn-Ube3a imprinted gene loci and their involvement in hereditary disorders. Front. Genet. 2012, 3:264. (PMID: 23226156).
    • (2012) Front. Genet. , vol.3 , pp. 264
    • Plagge, A.1
  • 18
    • 34548605504 scopus 로고    scopus 로고
    • Steroid receptor RNA activator (SRA1): unusual bifaceted gene products with suspected relevance to breast cancer
    • (PMID: 17710122)
    • Leygue E. Steroid receptor RNA activator (SRA1): unusual bifaceted gene products with suspected relevance to breast cancer. Nucl. Recept. Signal. 2007, 5:e006. (PMID: 17710122).
    • (2007) Nucl. Recept. Signal. , vol.5 , pp. e006
    • Leygue, E.1
  • 19
    • 84907032373 scopus 로고    scopus 로고
    • LncRNAtor: a comprehensive resource for functional investigation of long non-coding RNAs
    • (PMID: 24813212)
    • Park C., Yu N., Choi I., Kim W., Lee S. lncRNAtor: a comprehensive resource for functional investigation of long non-coding RNAs. Bioinformatics 2014, 30(17):2480-2485. (PMID: 24813212).
    • (2014) Bioinformatics , vol.30 , Issue.17 , pp. 2480-2485
    • Park, C.1    Yu, N.2    Choi, I.3    Kim, W.4    Lee, S.5
  • 20
    • 84903136092 scopus 로고    scopus 로고
    • LnCeDB: database of human long noncoding RNA acting as competing endogenous RNA
    • (PMID: 24926662)
    • Das S., Ghosal S., Sen R., Chakrabarti J. lnCeDB: database of human long noncoding RNA acting as competing endogenous RNA. PLoS One 2014, 9(6):e98965. (PMID: 24926662).
    • (2014) PLoS One , vol.9 , Issue.6 , pp. e98965
    • Das, S.1    Ghosal, S.2    Sen, R.3    Chakrabarti, J.4
  • 21
    • 84908393813 scopus 로고    scopus 로고
    • GENCODE pseudogenes
    • (PMID: 24823776)
    • Frankish A., Harrow J. GENCODE pseudogenes. Methods Mol. Biol. 2014, 1167:129-155. (PMID: 24823776).
    • (2014) Methods Mol. Biol. , vol.1167 , pp. 129-155
    • Frankish, A.1    Harrow, J.2
  • 22
    • 84879987789 scopus 로고    scopus 로고
    • LincRNAs: genomics, evolution, and mechanisms
    • (Review. PMID: 23827673)
    • Ulitsky I., Bartel D.P. lincRNAs: genomics, evolution, and mechanisms. Cell 2013, 154(1):26-46. (Review. PMID: 23827673). 10.1016/j.cell.2013.06.020.
    • (2013) Cell , vol.154 , Issue.1 , pp. 26-46
    • Ulitsky, I.1    Bartel, D.P.2
  • 23
    • 84877712982 scopus 로고    scopus 로고
    • Gene duplication as a major force in evolution
    • (PMID: 23640422)
    • Magadum S., Banerjee U., Murugan P., Gangapur D., Ravikesavan R. Gene duplication as a major force in evolution. J. Genet. 2013, 92(1):155-161. (PMID: 23640422).
    • (2013) J. Genet. , vol.92 , Issue.1 , pp. 155-161
    • Magadum, S.1    Banerjee, U.2    Murugan, P.3    Gangapur, D.4    Ravikesavan, R.5
  • 24
    • 33745125901 scopus 로고    scopus 로고
    • Avner P The Xist RNA gene evolved in eutherians by pseudogenization of a protein-coding gene
    • (PMID: 16778056)
    • Duret L., Chureau C., Samain S., Weissenbach J. Avner P The Xist RNA gene evolved in eutherians by pseudogenization of a protein-coding gene. Science 2006, 312(5780):1653-1655. (PMID: 16778056).
    • (2006) Science , vol.312 , Issue.5780 , pp. 1653-1655
    • Duret, L.1    Chureau, C.2    Samain, S.3    Weissenbach, J.4
  • 25
    • 84902682913 scopus 로고    scopus 로고
    • The RIDL hypothesis: transposable elements as functional domains of long noncoding RNAs
    • (PMID: 24850885)
    • Johnson R., Guigó R. The RIDL hypothesis: transposable elements as functional domains of long noncoding RNAs. RNA 2014, 20(7):959-976. (PMID: 24850885).
    • (2014) RNA , vol.20 , Issue.7 , pp. 959-976
    • Johnson, R.1    Guigó, R.2
  • 26
    • 84937251257 scopus 로고    scopus 로고
    • Transposable elements reveal a stem cell-specific class of long noncoding RNAs
    • (PMID: 23181609)
    • Kelley D., Rinn J. Transposable elements reveal a stem cell-specific class of long noncoding RNAs. Genome Biol. 2012, 1(11):R10. (PMID: 23181609).
    • (2012) Genome Biol. , vol.1 , Issue.11 , pp. R10
    • Kelley, D.1    Rinn, J.2
  • 27
    • 84879167033 scopus 로고    scopus 로고
    • Staufen-mediated mRNA decay
    • (PMID: 23681777)
    • Park E., Maquat L.E. Staufen-mediated mRNA decay. Wiley Interdiscip. Rev. RNA 2013, 4(4):423-435. (PMID: 23681777).
    • (2013) Wiley Interdiscip. Rev. RNA , vol.4 , Issue.4 , pp. 423-435
    • Park, E.1    Maquat, L.E.2
  • 28
    • 79952389412 scopus 로고    scopus 로고
    • The transcribed-ultraconserved regions: a novel class of long noncoding RNAs involved in cancer susceptibility
    • (PMID: 21298224)
    • Scaruffi P. The transcribed-ultraconserved regions: a novel class of long noncoding RNAs involved in cancer susceptibility. ScientificWorldJournal 2011, 11:340-352. (PMID: 21298224).
    • (2011) ScientificWorldJournal , vol.11 , pp. 340-352
    • Scaruffi, P.1
  • 29
    • 84928029167 scopus 로고    scopus 로고
    • Comparison of splice sites reveals that long noncoding RNAs are evolutionarily well conserved
    • (PMID: 25802408)
    • Nitsche A., Rose D., Fasold M., Reiche K., Stadler P.F. Comparison of splice sites reveals that long noncoding RNAs are evolutionarily well conserved. RNA 2015, 21(5):801-812. (PMID: 25802408).
    • (2015) RNA , vol.21 , Issue.5 , pp. 801-812
    • Nitsche, A.1    Rose, D.2    Fasold, M.3    Reiche, K.4    Stadler, P.F.5
  • 30
    • 84887376115 scopus 로고    scopus 로고
    • ANRIL/CDKN2B-AS shows two-stage clade-specific evolution and becomes conserved after transposon insertions in simians
    • (PMID: 24225082)
    • He S., Gu W., Li Y., Zhu H. ANRIL/CDKN2B-AS shows two-stage clade-specific evolution and becomes conserved after transposon insertions in simians. BMC Evol. Biol. 2013, 13:247. (PMID: 24225082).
    • (2013) BMC Evol. Biol. , vol.13 , pp. 247
    • He, S.1    Gu, W.2    Li, Y.3    Zhu, H.4
  • 31
    • 24944460598 scopus 로고    scopus 로고
    • Shelterin: the protein complex that shapes and safeguards human telomeres
    • (PMID: 16166375)
    • de Lange T. Shelterin: the protein complex that shapes and safeguards human telomeres. Genes Dev. 2005, 19(18):2100-2110. (PMID: 16166375).
    • (2005) Genes Dev. , vol.19 , Issue.18 , pp. 2100-2110
    • de Lange, T.1
  • 32
    • 84896730316 scopus 로고    scopus 로고
    • TERRA-reinforced association of LSD1 with MRE11 promotes processing of uncapped telomeres
    • (PMID: 24529708)
    • Porro A., Feuerhahn S., Lingner J. TERRA-reinforced association of LSD1 with MRE11 promotes processing of uncapped telomeres. Cell Rep. 2014, 6(4):765-776. (PMID: 24529708).
    • (2014) Cell Rep. , vol.6 , Issue.4 , pp. 765-776
    • Porro, A.1    Feuerhahn, S.2    Lingner, J.3
  • 33
    • 84878934258 scopus 로고    scopus 로고
    • DNA repair at telomeres: keeping the ends intact
    • (PMID: 23732473)
    • Webb C.J., Wu Y., Zakian V.A. DNA repair at telomeres: keeping the ends intact. Cold Spring Harb. Perspect. Biol. 2013, 5(6):a012666. (PMID: 23732473).
    • (2013) Cold Spring Harb. Perspect. Biol. , vol.5 , Issue.6 , pp. a012666
    • Webb, C.J.1    Wu, Y.2    Zakian, V.A.3
  • 34
    • 79953033701 scopus 로고    scopus 로고
    • TERRA and hnRNPA1 orchestrate an RPA-to-POT1 switch on telomeric single-stranded DNA
    • (PMID: 21399625)
    • Flynn R.L., Centore R.C., O'Sullivan R.J., Rai R., Tse A., Songyang Z., Chang S., Karlseder J., Zou L. TERRA and hnRNPA1 orchestrate an RPA-to-POT1 switch on telomeric single-stranded DNA. Nature 2011, 471(7339):532-536. (PMID: 21399625).
    • (2011) Nature , vol.471 , Issue.7339 , pp. 532-536
    • Flynn, R.L.1    Centore, R.C.2    O'Sullivan, R.J.3    Rai, R.4    Tse, A.5    Songyang, Z.6    Chang, S.7    Karlseder, J.8    Zou, L.9
  • 35
    • 77957243987 scopus 로고    scopus 로고
    • The non-coding RNA TERRA is a natural ligand and direct inhibitor of human telomerase
    • (PMID: 20460456)
    • Redon S., Reichenbach P., Lingner J. The non-coding RNA TERRA is a natural ligand and direct inhibitor of human telomerase. Nucleic Acids Res. 2010, 38(17):5797-5806. (PMID: 20460456).
    • (2010) Nucleic Acids Res. , vol.38 , Issue.17 , pp. 5797-5806
    • Redon, S.1    Reichenbach, P.2    Lingner, J.3
  • 36
    • 84884564107 scopus 로고    scopus 로고
    • Telomeric noncoding RNA TERRA is induced by telomere shortening to nucleate telomerase molecules at short telomeres
    • (PMID: 24074956)
    • Cusanelli E., Romero C.A., Chartrand P. Telomeric noncoding RNA TERRA is induced by telomere shortening to nucleate telomerase molecules at short telomeres. Mol. Cell 2013, 51(6):780-791. (PMID: 24074956).
    • (2013) Mol. Cell , vol.51 , Issue.6 , pp. 780-791
    • Cusanelli, E.1    Romero, C.A.2    Chartrand, P.3
  • 37
    • 84895807392 scopus 로고    scopus 로고
    • Telomeric transcripts stimulate telomere recombination to suppress senescence in cells lacking telomerase
    • (PMID: 24550456)
    • Yu T.Y., Kao Y.W., Lin J.J. Telomeric transcripts stimulate telomere recombination to suppress senescence in cells lacking telomerase. Proc. Natl. Acad. Sci. U. S. A. 2014, 111(9):3377-3382. (PMID: 24550456).
    • (2014) Proc. Natl. Acad. Sci. U. S. A. , vol.111 , Issue.9 , pp. 3377-3382
    • Yu, T.Y.1    Kao, Y.W.2    Lin, J.J.3
  • 39
    • 84886777912 scopus 로고    scopus 로고
    • Chromosomal contact permits transcription between coregulated genes
    • (PMID: 24243018)
    • Fanucchi S., Shibayama Y., Burd S., Weinberg M.S., Mhlanga M.M. Chromosomal contact permits transcription between coregulated genes. Cell 2013, 155:606-620. (PMID: 24243018).
    • (2013) Cell , vol.155 , pp. 606-620
    • Fanucchi, S.1    Shibayama, Y.2    Burd, S.3    Weinberg, M.S.4    Mhlanga, M.M.5
  • 41
    • 84874368349 scopus 로고    scopus 로고
    • Activating RNAs associate with Mediator to enhance chromatin architecture and transcription
    • (PMID: 23417068)
    • Lai F., Orom U.A., Cesaroni M., Beringer M., Taatjes D.J., Blobel G.A., Shiekhattar R. Activating RNAs associate with Mediator to enhance chromatin architecture and transcription. Nature 2013, 494:497-501. (PMID: 23417068).
    • (2013) Nature , vol.494 , pp. 497-501
    • Lai, F.1    Orom, U.A.2    Cesaroni, M.3    Beringer, M.4    Taatjes, D.J.5    Blobel, G.A.6    Shiekhattar, R.7
  • 42
    • 0029919678 scopus 로고    scopus 로고
    • Expression of the rat BFGF antisense RNA transcript is tissue-specific and developmentally regulated
    • (PMID: 8735597)
    • Li A.W., Seyoum G., Shiu R.P., Murphy P.R. Expression of the rat BFGF antisense RNA transcript is tissue-specific and developmentally regulated. Mol. Cell. Endocrinol. 1996, 118(1-2):113-123. (PMID: 8735597).
    • (1996) Mol. Cell. Endocrinol. , vol.118 , Issue.1-2 , pp. 113-123
    • Li, A.W.1    Seyoum, G.2    Shiu, R.P.3    Murphy, P.R.4
  • 43
    • 84883816842 scopus 로고    scopus 로고
    • Guided by RNAs: X-inactivation as a model for lncRNA function
    • (PMID: 23816838)
    • Froberg J.E., Yang L., Lee J.T. Guided by RNAs: X-inactivation as a model for lncRNA function. J. Mol. Biol. 2013, 425(19):3698-3706. (PMID: 23816838).
    • (2013) J. Mol. Biol. , vol.425 , Issue.19 , pp. 3698-3706
    • Froberg, J.E.1    Yang, L.2    Lee, J.T.3
  • 44
    • 42149084976 scopus 로고    scopus 로고
    • Epigenetic mechanisms of gene regulation during mammalian spermatogenesis
    • (PMID: 18416029)
    • Khalil A.M., Wahlestedt C. Epigenetic mechanisms of gene regulation during mammalian spermatogenesis. Epigenetics 2008, 3(1):21-28. (PMID: 18416029).
    • (2008) Epigenetics , vol.3 , Issue.1 , pp. 21-28
    • Khalil, A.M.1    Wahlestedt, C.2
  • 46
    • 78751662908 scopus 로고    scopus 로고
    • The Polycomb complex PRC2 and its mark in life
    • (PMID: 21248841)
    • Margueron R., Reinberg D. The Polycomb complex PRC2 and its mark in life. Nature 2011, 469(7330):343-349. (PMID: 21248841).
    • (2011) Nature , vol.469 , Issue.7330 , pp. 343-349
    • Margueron, R.1    Reinberg, D.2
  • 49
    • 84879811291 scopus 로고    scopus 로고
    • The long non-coding RNA nuclear-enriched abundant transcript 1_2 induces paraspeckle formation in the motor neuron during the early phase of amyotrophic lateral sclerosis
    • (PMID: 23835137)
    • Nishimoto Y., Nakagawa S., Hirose T., Okano H.J., Takao M., Shibata S., Suyama S., Kuwako K., Imai T., Murayama S., Suzuki N., Okano H. The long non-coding RNA nuclear-enriched abundant transcript 1_2 induces paraspeckle formation in the motor neuron during the early phase of amyotrophic lateral sclerosis. Mol. Brain 2013, 6:31. (PMID: 23835137).
    • (2013) Mol. Brain , vol.6 , pp. 31
    • Nishimoto, Y.1    Nakagawa, S.2    Hirose, T.3    Okano, H.J.4    Takao, M.5    Shibata, S.6    Suyama, S.7    Kuwako, K.8    Imai, T.9    Murayama, S.10    Suzuki, N.11    Okano, H.12
  • 50
    • 81055140863 scopus 로고    scopus 로고
    • NcRNA- and Pc2 methylation-dependent gene relocation between nuclear structures mediates gene activation programs
    • (PMID: 22078878)
    • Yang L., Lin C., Liu W., Zhang J., Ohgi K.A., Grinstein J.D., Dorrestein P.C., Rosenfeld M.G. ncRNA- and Pc2 methylation-dependent gene relocation between nuclear structures mediates gene activation programs. Cell 2011, 147(4):773-788. (PMID: 22078878).
    • (2011) Cell , vol.147 , Issue.4 , pp. 773-788
    • Yang, L.1    Lin, C.2    Liu, W.3    Zhang, J.4    Ohgi, K.A.5    Grinstein, J.D.6    Dorrestein, P.C.7    Rosenfeld, M.G.8
  • 51
    • 84891923027 scopus 로고    scopus 로고
    • Perspectives on the mechanism of transcriptional regulation by long non-coding RNAs
    • (PMID: 24149621)
    • Roberts T.C., Morris K.V., Weinberg M.S. Perspectives on the mechanism of transcriptional regulation by long non-coding RNAs. Epigenetics 2014, 9(1):13-20. (PMID: 24149621).
    • (2014) Epigenetics , vol.9 , Issue.1 , pp. 13-20
    • Roberts, T.C.1    Morris, K.V.2    Weinberg, M.S.3
  • 52
    • 84887419464 scopus 로고    scopus 로고
    • Promiscuous RNA binding by Polycomb repressive complex 2
    • (PMID: 24077223)
    • Davidovich C., Zheng L., Goodrich K.J., Cech T.R. Promiscuous RNA binding by Polycomb repressive complex 2. Nat. Struct. Mol. Biol. 2013, 20(11):1250-1257. (PMID: 24077223).
    • (2013) Nat. Struct. Mol. Biol. , vol.20 , Issue.11 , pp. 1250-1257
    • Davidovich, C.1    Zheng, L.2    Goodrich, K.J.3    Cech, T.R.4
  • 54
    • 69249217649 scopus 로고    scopus 로고
    • Regulatory roles of natural antisense transcripts
    • (PMID: 19638999)
    • Faghihi M.A., Wahlestedt C. Regulatory roles of natural antisense transcripts. Nat. Rev. Mol. Cell Biol. 2009, 10(9):637-643. (PMID: 19638999).
    • (2009) Nat. Rev. Mol. Cell Biol. , vol.10 , Issue.9 , pp. 637-643
    • Faghihi, M.A.1    Wahlestedt, C.2
  • 55
    • 84863861287 scopus 로고    scopus 로고
    • Regulation of chromatin structure by long noncoding RNAs: focus on natural antisense transcripts
    • (PMID: 22541732)
    • Magistri M., Faghihi M.A., St Laurent G., Wahlestedt C. Regulation of chromatin structure by long noncoding RNAs: focus on natural antisense transcripts. Trends Genet. 2012, 28(8):389-396. (PMID: 22541732).
    • (2012) Trends Genet. , vol.28 , Issue.8 , pp. 389-396
    • Magistri, M.1    Faghihi, M.A.2    St Laurent, G.3    Wahlestedt, C.4
  • 56
    • 84891936130 scopus 로고    scopus 로고
    • Non-coding RNAs as direct and indirect modulators of epigenetic regulation
    • (PMID: 24739571)
    • Peschansky V.J., Wahlestedt C. Non-coding RNAs as direct and indirect modulators of epigenetic regulation. Epigenetics 2014, 9(1):3-12. (PMID: 24739571).
    • (2014) Epigenetics , vol.9 , Issue.1 , pp. 3-12
    • Peschansky, V.J.1    Wahlestedt, C.2
  • 60
    • 84883806117 scopus 로고    scopus 로고
    • Posttranscriptional gene regulation by long noncoding RNA
    • (PMID: 23178169)
    • Yoon J.H., Abdelmohsen K., Gorospe M. Posttranscriptional gene regulation by long noncoding RNA. J. Mol. Biol. 2013, 425(19):3723-3730. (PMID: 23178169).
    • (2013) J. Mol. Biol. , vol.425 , Issue.19 , pp. 3723-3730
    • Yoon, J.H.1    Abdelmohsen, K.2    Gorospe, M.3
  • 62
    • 84876178165 scopus 로고    scopus 로고
    • Dysregulated A to I RNA editing and non-coding RNAs in neurodegeneration
    • (PMID: 23346095)
    • Singh M. Dysregulated A to I RNA editing and non-coding RNAs in neurodegeneration. Front. Genet. 2013, 3:326. (PMID: 23346095).
    • (2013) Front. Genet. , vol.3 , pp. 326
    • Singh, M.1
  • 63
    • 84890017364 scopus 로고    scopus 로고
    • Growth arrest on inhibition of nonsense-mediated decay is mediated by noncoding RNA GAS
    • (PMID: 24319682)
    • Mourtada-Maarabouni M., Williams G.T. Growth arrest on inhibition of nonsense-mediated decay is mediated by noncoding RNA GAS. Biomed. Res. Int. 2013, 2013:358015. (PMID: 24319682).
    • (2013) Biomed. Res. Int. , vol.2013 , pp. 358015
    • Mourtada-Maarabouni, M.1    Williams, G.T.2
  • 64
    • 79951495822 scopus 로고    scopus 로고
    • LncRNAs transactivate STAU1-mediated mRNA decay by duplexing with 3' UTRs via Alu elements
    • (PMID: 21307942)
    • Gong C., Maquat L.E. lncRNAs transactivate STAU1-mediated mRNA decay by duplexing with 3' UTRs via Alu elements. Nature 2011, 470(7333):284-288. (PMID: 21307942).
    • (2011) Nature , vol.470 , Issue.7333 , pp. 284-288
    • Gong, C.1    Maquat, L.E.2
  • 66
    • 84917697969 scopus 로고    scopus 로고
    • Long non-coding RNA UCA1 promotes breast tumor growth by suppression of p27 (Kip1)
    • (PMID: 24457952)
    • Huang J., Zhou N., Watabe K., Lu Z., Wu F., Xu M., Mo Y.Y. Long non-coding RNA UCA1 promotes breast tumor growth by suppression of p27 (Kip1). Cell Death Dis. 2014, 5:e1008. (PMID: 24457952).
    • (2014) Cell Death Dis. , vol.5 , pp. e1008
    • Huang, J.1    Zhou, N.2    Watabe, K.3    Lu, Z.4    Wu, F.5    Xu, M.6    Mo, Y.Y.7
  • 70
    • 84899912204 scopus 로고    scopus 로고
    • A long noncoding RNA, CHRF regulates cardiac hypertrophy by targeting miR-489
    • (PMID: 24557880)
    • Wang K., Liu F., Zhou L.Y., Long B., Yuan S.M., Wang Y., Liu C.Y., Sun T., Zhang X.J., Li P.F. A long noncoding RNA, CHRF regulates cardiac hypertrophy by targeting miR-489. Circ. Res. 2014, 114(9):1377-1388. (PMID: 24557880).
    • (2014) Circ. Res. , vol.114 , Issue.9 , pp. 1377-1388
    • Wang, K.1    Liu, F.2    Zhou, L.Y.3    Long, B.4    Yuan, S.M.5    Wang, Y.6    Liu, C.Y.7    Sun, T.8    Zhang, X.J.9    Li, P.F.10
  • 71
    • 84897438456 scopus 로고    scopus 로고
    • Modulation of hypoxia-signaling pathways by extracellular linc-RoR
    • (PMID: 24463816)
    • Takahashi K., Yan I.K., Haga H., Patel T. Modulation of hypoxia-signaling pathways by extracellular linc-RoR. J. Cell Sci. 2014, 127(Pt 7):1585-1594. (PMID: 24463816).
    • (2014) J. Cell Sci. , vol.127 , pp. 1585-1594
    • Takahashi, K.1    Yan, I.K.2    Haga, H.3    Patel, T.4
  • 72
    • 84883644241 scopus 로고    scopus 로고
    • Noncoding RNA in oncogenesis: a new era of identifying key players
    • (PMID: 24013378)
    • Deng G., Sui G. Noncoding RNA in oncogenesis: a new era of identifying key players. Int. J. Mol. Sci. 2013, 14(9):18319-18349. (PMID: 24013378).
    • (2013) Int. J. Mol. Sci. , vol.14 , Issue.9 , pp. 18319-18349
    • Deng, G.1    Sui, G.2
  • 73
    • 80054715378 scopus 로고    scopus 로고
    • A long noncoding RNA controls muscle differentiation by functioning as a competing endogenous RNA
    • (PMID: 22000014)
    • Cesana M., Cacchiarelli D., Legnini I., Santini T., Sthandier O., Chinappi M., Tramontano A., Bozzoni I. A long noncoding RNA controls muscle differentiation by functioning as a competing endogenous RNA. Cell 2011, 147(2):358-369. (PMID: 22000014).
    • (2011) Cell , vol.147 , Issue.2 , pp. 358-369
    • Cesana, M.1    Cacchiarelli, D.2    Legnini, I.3    Santini, T.4    Sthandier, O.5    Chinappi, M.6    Tramontano, A.7    Bozzoni, I.8
  • 75
    • 84903736048 scopus 로고    scopus 로고
    • Regulation of pri-miRNA processing by a long noncoding RNA transcribed from an ultraconserved region
    • (PMID: 24910097)
    • Liz J., Portela A., Soler M., Gómez A., Ling H., Michlewski G., Calin G.A., Guil S., Esteller M. Regulation of pri-miRNA processing by a long noncoding RNA transcribed from an ultraconserved region. Mol. Cell 2014, 55(1):138-147. (PMID: 24910097).
    • (2014) Mol. Cell , vol.55 , Issue.1 , pp. 138-147
    • Liz, J.1    Portela, A.2    Soler, M.3    Gómez, A.4    Ling, H.5    Michlewski, G.6    Calin, G.A.7    Guil, S.8    Esteller, M.9
  • 78
    • 84899854471 scopus 로고    scopus 로고
    • Microarray profiling and co-expression network analysis of circulating lncRNAs and mRNAs associated with major depressive disorder
    • (PMID: 24676134)
    • Liu Z., Li X., Sun N., Xu Y., Meng Y., Yang C., Wang Y., Zhang K. Microarray profiling and co-expression network analysis of circulating lncRNAs and mRNAs associated with major depressive disorder. PLoS One 2014, 9(3):e93388. (PMID: 24676134).
    • (2014) PLoS One , vol.9 , Issue.3 , pp. e93388
    • Liu, Z.1    Li, X.2    Sun, N.3    Xu, Y.4    Meng, Y.5    Yang, C.6    Wang, Y.7    Zhang, K.8
  • 79
    • 84901398883 scopus 로고    scopus 로고
    • Extracellular vesicle-mediated transfer of long non-coding RNA ROR modulates chemosensitivity in human hepatocellular cancer
    • (PMID: 24918061)
    • Takahashi K., Yan I.K., Kogure T., Haga H., Patel T. Extracellular vesicle-mediated transfer of long non-coding RNA ROR modulates chemosensitivity in human hepatocellular cancer. FEBS Open Bio 2014, 4:458-467. (PMID: 24918061).
    • (2014) FEBS Open Bio , vol.4 , pp. 458-467
    • Takahashi, K.1    Yan, I.K.2    Kogure, T.3    Haga, H.4    Patel, T.5
  • 80
    • 84897833980 scopus 로고    scopus 로고
    • TF2LncRNA: identifying common transcription factors for a list of lncRNA genes from ChIP-Seq data
    • (PMID: 24729968)
    • Jiang Q., Wang J., Wang Y., Ma R., Wu X., Li Y. TF2LncRNA: identifying common transcription factors for a list of lncRNA genes from ChIP-Seq data. Biomed. Res. Int. 2014, 2014:317642. (PMID: 24729968).
    • (2014) Biomed. Res. Int. , vol.2014 , pp. 317642
    • Jiang, Q.1    Wang, J.2    Wang, Y.3    Ma, R.4    Wu, X.5    Li, Y.6
  • 83
    • 84902161967 scopus 로고    scopus 로고
    • Dark matter RNA illuminates the puzzle of genome-wide association studies
    • (PMID: 24924000)
    • St Laurent G., Vyatkin Y., Kapranov P. Dark matter RNA illuminates the puzzle of genome-wide association studies. BMC Med. 2014, 12:97. (PMID: 24924000).
    • (2014) BMC Med. , vol.12 , pp. 97
    • St Laurent, G.1    Vyatkin, Y.2    Kapranov, P.3
  • 85
    • 84937252629 scopus 로고    scopus 로고
    • Oligonucleotides for upregulating gene expression
    • (PMID: 24237027)
    • Khorkova O., Hsiao J., Wahlestedt C. Oligonucleotides for upregulating gene expression. Pharm. Pat. Anal. 2013, 2(2):215-229. (PMID: 24237027).
    • (2013) Pharm. Pat. Anal. , vol.2 , Issue.2 , pp. 215-229
    • Khorkova, O.1    Hsiao, J.2    Wahlestedt, C.3
  • 86
    • 84925235630 scopus 로고    scopus 로고
    • De-repressing LncRNA-targeted genes to upregulate gene expression: focus on small molecule therapeutics
    • (PMID: 25405465)
    • Fatemi R.P., Velmeshev D., Faghihi M.A. De-repressing LncRNA-targeted genes to upregulate gene expression: focus on small molecule therapeutics. Mol. Ther.-Nucleic Acids 2014, 3:e196. (PMID: 25405465).
    • (2014) Mol. Ther.-Nucleic Acids , vol.3 , pp. e196
    • Fatemi, R.P.1    Velmeshev, D.2    Faghihi, M.A.3
  • 87
    • 84896823260 scopus 로고    scopus 로고
    • LncRNAs: new players in apoptosis control
    • (PMID: 24627686)
    • Rossi M.N., Antonangeli F. LncRNAs: new players in apoptosis control. Int. J. Cell Biol. 2014, 2014:473857. (PMID: 24627686).
    • (2014) Int. J. Cell Biol. , vol.2014 , pp. 473857
    • Rossi, M.N.1    Antonangeli, F.2
  • 90
    • 84887101163 scopus 로고    scopus 로고
    • MicroRNAs and other non-coding RNAs as targets for anticancer drug development
    • (PMID: 24172333)
    • Ling H., Fabbri M., Calin G.A. MicroRNAs and other non-coding RNAs as targets for anticancer drug development. Nat. Rev. Drug Discov. 2013, 12(11):847-865. (PMID: 24172333).
    • (2013) Nat. Rev. Drug Discov. , vol.12 , Issue.11 , pp. 847-865
    • Ling, H.1    Fabbri, M.2    Calin, G.A.3
  • 93
    • 84884525392 scopus 로고    scopus 로고
    • Variations in ncRNA gene LOC284889 and MIF-794CATT repeats are associated with malaria susceptibility in Indian populations
    • (PMID: 24066864)
    • Jha A.N., Sundaravadivel P., Pati S.S., Patra P.K., Thangaraj K. Variations in ncRNA gene LOC284889 and MIF-794CATT repeats are associated with malaria susceptibility in Indian populations. Malar. J. 2013, 12:345. (PMID: 24066864).
    • (2013) Malar. J. , vol.12 , pp. 345
    • Jha, A.N.1    Sundaravadivel, P.2    Pati, S.S.3    Patra, P.K.4    Thangaraj, K.5
  • 94
    • 84874025014 scopus 로고    scopus 로고
    • The NeST long ncRNA controls microbial susceptibility and epigenetic activation of the interferon-γ locus
    • (PMID: 23415224)
    • Gomez J.A., Wapinski O.L., Yang Y.W., Bureau J.F., Gopinath S., Monack D.M., Chang H.Y., Brahic M., Kirkegaard K. The NeST long ncRNA controls microbial susceptibility and epigenetic activation of the interferon-γ locus. Cell 2013, 152(4):743-754. (PMID: 23415224).
    • (2013) Cell , vol.152 , Issue.4 , pp. 743-754
    • Gomez, J.A.1    Wapinski, O.L.2    Yang, Y.W.3    Bureau, J.F.4    Gopinath, S.5    Monack, D.M.6    Chang, H.Y.7    Brahic, M.8    Kirkegaard, K.9
  • 95
    • 84923536034 scopus 로고    scopus 로고
    • Non-coding RNA in neural function, disease, and aging
    • (PMID: 25806046)
    • Szafranski K., Abraham K.J., Mekhail K. Non-coding RNA in neural function, disease, and aging. Front. Genet. 2015, 6:87. (PMID: 25806046).
    • (2015) Front. Genet. , vol.6 , pp. 87
    • Szafranski, K.1    Abraham, K.J.2    Mekhail, K.3
  • 96
    • 84924134321 scopus 로고    scopus 로고
    • Long noncoding RNAs in cardiovascular diseases
    • (PMID: 25677520)
    • Uchida S., Dimmeler S. Long noncoding RNAs in cardiovascular diseases. Circ. Res. 2015, 116(4):737-750. (PMID: 25677520).
    • (2015) Circ. Res. , vol.116 , Issue.4 , pp. 737-750
    • Uchida, S.1    Dimmeler, S.2
  • 97
    • 84901198797 scopus 로고    scopus 로고
    • Spatially conserved regulatory elements identified within human and mouse Cd247 gene using high-throughput sequencing data from the ENCODE project
    • (PMID: 24797614)
    • Pundhir S., Hannibal T.D., Bang-Berthelsen C.H., Wegener A.M., Pociot F., Holmberg D., Gorodkin J. Spatially conserved regulatory elements identified within human and mouse Cd247 gene using high-throughput sequencing data from the ENCODE project. Gene 2014, 545(1):80-87. (PMID: 24797614).
    • (2014) Gene , vol.545 , Issue.1 , pp. 80-87
    • Pundhir, S.1    Hannibal, T.D.2    Bang-Berthelsen, C.H.3    Wegener, A.M.4    Pociot, F.5    Holmberg, D.6    Gorodkin, J.7
  • 100
    • 84875070091 scopus 로고    scopus 로고
    • Non-coding RNAs: functional aspects and diagnostic utility in oncology
    • (PMID: 23455466)
    • Kim T., Reitmair A. Non-coding RNAs: functional aspects and diagnostic utility in oncology. Int. J. Mol. Sci. 2013, 14(3):4934-4968. (PMID: 23455466).
    • (2013) Int. J. Mol. Sci. , vol.14 , Issue.3 , pp. 4934-4968
    • Kim, T.1    Reitmair, A.2


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