Negative regulation of lncRNA GAS5 by miR-21

Cell Death and Differentiation

Volumn 20, Issue 11, 2013, Pages 1558-1568

  Zhang, Z ^a   Zhu, Z ^b   Watabe, K ^a   Zhang, X ^c   Bai, C ^d   Xu, M ^e   Wu, F ^a,f   Mo, Y Y ^a  

^a UNIVERSITY OF MISSISSIPPI SCHOOL OF MEDICINE   (United States)

^b THE FIRST AFFILIATED HOSPITAL OF SHANDONG FIRST MEDICAL UNIVERSITY   (China)

^c UNIVERSITY OF MISSISSIPPI MEDICAL CENTER   (United States)

^d FUDAN UNIVERSITY   (China)

^e AFFILIATED HOSPITAL OF JIANGSU UNIVERSITY   (China)

^f System Biosciences   (United States)

Author keywords

GAS5; lncRNA; miR 21; oncogene; post transcriptional regulation; tumor suppressor

Indexed keywords

CARRIER PROTEINS AND BINDING PROTEINS; GROWTH ARREST SPECIFIC PROTEIN 5; LONG UNTRANSLATED RNA; MICRORNA 21; RNA INDUCED SILENCING COMPLEX; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BINDING SITE; BREAST CANCER; CELL CONTACT; CELL DENSITY; CELL INVASION; CELLULAR STRESS RESPONSE; CONTROLLED STUDY; EXON; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATOR GENE; RNA PROBE; TRANSCRIPTION REGULATION; TUMOR SUPPRESSOR GENE; UPREGULATION;

ANIMALS; CELL LINE, TUMOR; FEMALE; GENES, TUMOR SUPPRESSOR; HETEROGRAFTS; HUMANS; IN SITU HYBRIDIZATION; MCF-7 CELLS; MICE; MICE, NUDE; MICRORNAS; PLASMIDS; RNA, LONG NONCODING; TRANSFECTION; UP-REGULATION;

EID: 84885423196     PISSN: 13509047     EISSN: 14765403     Source Type: Journal    
DOI: 10.1038/cdd.2013.110     Document Type: Article

References (57)

1. Pillai RS. MicroRNA function: multiple mechanisms for a tiny RNA? RNA 2005; 11: 1753-1761.
2. Zamore PD, Haley B. Ribo-gnome: the big world of small RNAs. Science 2005; 309: 1519-1524.
3. Bartel DP. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 2004; 116: 281-297.
4. Calin GA, Croce CM. MicroRNA signatures in human cancers. Nat Rev Cancer 2006; 6: 857-866.
5. Schetter AJ, Leung SY, Sohn JJ, Zanetti KA, Bowman ED, Yanaihara N et al. MicroRNA expression profiles associated with prognosis and therapeutic outcome in colon adenocarcinoma. JAMA 2008; 299: 425-436.
6. Jiang J, Gusev Y, Aderca I, Mettler TA, Nagorney DM, Brackett DJ et al. Association of MicroRNA expression in hepatocellular carcinomas with hepatitis infection, cirrhosis, and patient survival. Clin Cancer Res 2008; 14: 419-427.
7. Mathe EA, Nguyen GH, Bowman ED, Zhao Y, Budhu A, Schetter AJ et al. MicroRNA expression in squamous cell carcinoma and adenocarcinoma of the esophagus: associations with survival. Clin Cancer Res 2009; 15: 6192-6200.
8. Hui AB, Lenarduzzi M, Krushel T, Waldron L, Pintilie M, Shi W et al. Comprehensive MicroRNA profiling for head and neck squamous cell carcinomas. Clin Cancer Res 16: 1129-1139.
9. Selaru FM, Olaru AV, Kan T, David S, Cheng Y, Mori Y et al. MicroRNA-21 is overexpressed in human cholangiocarcinoma and regulates programmed cell death 4 and tissue inhibitor of metalloproteinase 3. Hepatology 2009; 49: 1595-1601.
10. Chan JA, Krichevsky AM, Kosik KS. MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells. Cancer Res 2005; 65: 6029-6033.
11. Si ML, Zhu S, Wu H, Lu Z, Wu F, Mo YY. miR-21-mediated tumor growth. Oncogene 2007; 26: 2799-2803.
12. Zhu S, Wu H, Wu F, Nie D, Sheng S, Mo YY. MicroRNA-21 targets tumor suppressor genes in invasion and metastasis. Cell Res 2008; 18: 350-359.
13. Medina PP, Nolde M, Slack FJ. OncomiR addiction in an in vivo model of microRNA-21-induced pre-B-cell lymphoma. Nature 467: 86-90.
14. Meng F, Henson R, Wehbe-Janek H, Ghoshal K, Jacob ST, Patel T. MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer. Gastroenterology 2007; 133: 647-658.
15. Zhu S, Si ML, Wu H, Mo YY. MicroRNA-21 targets the tumor suppressor gene tropomyosin 1 (TPM1). J Biol Chem 2007; 282: 14328-14336.
16. Frankel LB, Christoffersen NR, Jacobsen A, Lindow M, Krogh A, Lund AH. Programmed cell death 4 (PDCD4) is an important functional target of the microRNA miR-21 in breast cancer cells. J Biol Chem 2008; 283: 1026-1033.
17. Asangani IA, Rasheed SA, Nikolova DA, Leupold JH, Colburn NH, Post S et al. MicroRNA-21 (miR-21) post-transcriptionally downregulates tumor suppressor Pdcd4 and stimulates invasion, intravasation and metastasis in colorectal cancer. Oncogene 2008; 27: 2128-2136.
18. Lu Z, Liu M, Stribinskis V, Klinge CM, Ramos KS, Colburn NH et al. MicroRNA-21 promotes cell transformation by targeting the programmed cell death 4 gene. Oncogene 2008; 27: 4373-4379.
19. Lee JT. Epigenetic regulation by long noncoding RNAs. Science 2012; 338: 1435-1439.
20. Prensner JR, Chinnaiyan AM. The emergence of lncRNAs in cancer biology. Cancer Discov 2011; 1: 391-407.
21. Gutschner T, Diederichs S. The hallmarks of cancer: a long non-coding RNA point of view. RNA Biol 2012; 9: 703-719.
22. Schneider C, King RM, Philipson L. Genes specifically expressed at growth arrest of mammalian cells. Cell 1988; 54: 787-793.
23. Mourtada-Maarabouni M, Pickard MR, Hedge VL, Farzaneh F, Williams GT. GAS5, a non-protein-coding RNA, controls apoptosis and is downregulated in breast cancer. Oncogene 2009; 28: 195-208.
24. Carninci P, Kasukawa T, Katayama S, Gough J, Frith MC, Maeda N et al. The transcriptional landscape of the mammalian genome. Science 2005; 309: 1559-1563.
25. Ajioka I, Maeda T, Nakajima K. Large-scale correlation of DNA accession numbers to the cDNAs in the FANTOM full-length mouse cDNA clone set. Keio J Med 2006; 55: 107-110.
26. Kino T, Hurt DE, Ichijo T, Nader N, Chrousos GP. Noncoding RNA gas5 is a growth arrest-and starvation-associated repressor of the glucocorticoid receptor. Science Signal 2010; 3: ra8.
27. Liu Q, Huang J, Zhou N, Zhang Z, Zhang A, Lu Z et al. LncRNA loc285194 is a p53-regulated tumor suppressor. Nucleic Acids Res 2013; 41: 4976-4987.
28. Coccia EM, Cicala C, Charlesworth A, Ciccarelli C, Rossi GB, Philipson L et al. Regulation and expression of a growth arrest-specific gene (gas5) during growth, differentiation, and development. Mol Cel Biol 1992; 12: 3514-3521.
29. Salmena L, Poliseno L, Tay Y, Kats L, Pandolfi PP. A ceRNA hypothesis: the Rosetta Stone of a hidden RNA language? Cell 2011; 146: 353-358.
30. He L, Thomson JM, Hemann MT, Hernando-Monge E, Mu D, Goodson S et al. A microRNA polycistron as a potential human oncogene. Nature 2005; 435: 828-833.
31. O'Donnell KA, Wentzel EA, Zeller KI, Dang CV, Mendell JT. c-Myc-regulated microRNAs modulate E2F1 expression. Nature 2005; 435: 839-843.
32. Xi Y, Shalgi R, Fodstad O, Pilpel Y, Ju J. Differentially regulated micro-RNAs and actively translated messenger RNA transcripts by tumor suppressor p53 in colon cancer. Clin Cancer Res 2006; 12(7 Pt 1): 2014-2024.
33. He X, He L, Hannon GJ. The guardian's little helper: microRNAs in the p53 tumor suppressor network. Cancer Res 2007; 67: 11099-11101.
34. Loffler D, Brocke-Heidrich K, Pfeifer G, Stocsits C, Hackermuller J, Kretzschmar AK et al. Interleukin-6 dependent survival of multiple myeloma cells involves the Stat3-mediated induction of microRNA-21 through a highly conserved enhancer. Blood 2007; 110: 1330-1333.
35. Fujita S, Ito T, Mizutani T, Minoguchi S, Yamamichi N, Sakurai K et al. miR-21 gene expression triggered by AP-1 is sustained through a double-negative feedback mechanism. J Mol Biol 2008; 378: 492-504.
36. Huang TH, Wu F, Loeb GB, Hsu R, Heidersbach A, Brincat A et al. Up-regulation of miR-21 by HER2/neu signaling promotes cell invasion. J Biol Chem 2009; 284: 18515-18524.
37. Singh SK, Kagalwala MN, Parker-Thornburg J, Adams H, Majumder S. REST maintains self-renewal and pluripotency of embryonic stem cells. Nature 2008; 453: 223-227.
38. Saito Y, Liang G, Egger G, Friedman JM, Chuang JC, Coetzee GA et al. Specific activation of microRNA-127 with downregulation of the proto-oncogene BCL6 by chromatin-modifying drugs in human cancer cells. Cancer Cell 2006; 9: 435-443.
39. Scott GK, Mattie MD, Berger CE, Benz SC, Benz CC. Rapid alteration of microRNA levels by histone deacetylase inhibition. Cancer Res 2006; 66: 1277-1281.
40. Newman MA, Thomson JM, Hammond SM. Lin-28 interaction with the Let-7 precursor loop mediates regulated microRNA processing. RNA 2008; 14: 1539-1549.
41. Piskounova E, Viswanathan SR, Janas M, LaPierre RJ, Daley GQ, Sliz P et al. Determinants of microRNA processing inhibition by the developmentally regulated RNA-binding protein Lin28. J Biol Chem 2008; 283: 21310-21314.
42. Rybak A, Fuchs H, Smirnova L, Brandt C, Pohl EE, Nitsch R et al. A feedback loop comprising lin-28 and let-7 controls pre-let-7 maturation during neural stem-cell commitment. Nat Cell Biol 2008; 10: 987-993.
43. Viswanathan SR, Daley GQ, Gregory RI. Selective blockade of microRNA processing by Lin28. Science 2008; 320: 97-100.
44. Davis BN, Hilyard AC, Lagna G, Hata A. SMAD proteins control DROSHA-mediated microRNA maturation. Nature 2008; 454: 56-61.
45. Kim YJ, Park SJ, Choi EY, Kim S, Kwak HJ, Yoo BC et al. PTEN modulates miR-21 processing via RNA-regulatory protein RNH1. PLoS One 2011; 6: e28308.
46. Calin GA, Liu CG, Ferracin M, Hyslop T, Spizzo R, Sevignani C et al. Ultraconserved regions encoding ncRNAs are altered in human leukemias and carcinomas. Cancer Cell 2007; 12: 215-229.
47. Wang J, Liu X, Wu H, Ni P, Gu Z, Qiao Y et al. CREB up-regulates long non-coding RNA, HULC expression through interaction with microRNA-372 in liver cancer. Nucleic Acids Res 2010; 38: 5366-5383.
48. Cesana M, Cacchiarelli D, Legnini I, Santini T, Sthandier O, Chinappi M et al. A long noncoding RNA controls muscle differentiation by functioning as a competing endogenous RNA. Cell 2011; 147: 358-369.
49. Karreth FA, Tay Y, Perna D, Ala U, Tan SM, Rust AG et al. In vivo identification of tumor-suppressive PTEN ceRNAs in an oncogenic BRAF-induced mouse model of melanoma. Cell 2011; 147: 382-395.
50. Tay Y, Kats L, Salmena L, Weiss D, Tan SM, Ala U et al. Coding-independent regulation of the tumor suppressor PTEN by competing endogenous mRNAs. Cell 2011; 147: 344-357.
51. Sumazin P, Yang X, Chiu HS, Chung WJ, Iyer A, Llobet-Navas D et al. An extensive microRNA-mediated network of RNA-RNA interactions regulates established oncogenic pathways in glioblastoma. Cell 2011; 147: 370-381.
52. Amaral PP, Clark MB, Gascoigne DK, Dinger ME, Mattick JS. lncRNAdb: a reference database for long noncoding RNAs. Nucleic Acids Res 2011; 39: Database issue D146-D151.
53. Sachdeva M, Zhu S, Wu F, Wu H, Walia V, Kumar S et al. p53 represses c-Myc through induction of the tumor suppressor miR-145. Proc Natl Acad Sci USA 2009; 106: 3207-3212.
54. Zhang A, Zhou N, Huang J, Liu Q, Fukuda K, Ma D et al. The human long non-coding RNA-RoR is a p53 repressor in response to DNA damage. Cell Res 2012; 23: 340-350.
55. Gupta A, Mo YY. Detection of microRNAs in cultured cells and paraffin-embedded tissue specimens by in situ hybridization. Methods Mol Biol 2011; 676: 73-83.
56. Zhang A, Zhou N, Huang J, Liu Q, Fukuda K, Ma D et al. The human long non-coding RNA-RoR is a p53 repressor in response to DNA damage. Cell Res 2013; 23: 340-350.
57. Wu F, Chiocca S, Beck WT, Mo YY. Gam1-associated alterations of drug responsiveness through activation of apoptosis. Mol Cancer Ther 2007; 6: 1823-1830.