The long non-coding RNA nuclear-enriched abundant transcript 1-2 induces paraspeckle formation in the motor neuron during the early phase of amyotrophic lateral sclerosis

Molecular Brain

Volumn 6, Issue 1, 2013, Pages

  Nishimoto, Yoshinori ^a   Nakagawa, Shinichi ^b   Hirose, Tetsuro ^c   Okano, Hirotaka James ^a,d   Takao, Masaki ^e,f   Shibata, Shinsuke ^a   Suyama, Satoshi ^a   Kuwako, Ken Ichiro ^a   Imai, Takao ^a   Murayama, Shigeo ^f   Suzuki, Norihiro ^a   Okano, Hideyuki ^a  

^a KEIO UNIVERSITY   (Japan)

^b RIKEN   (Japan)

^c NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

^d JIKEI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^e Institute of Brain and Blood VesselsMihara Memorial Hospital   (Japan)

^f Tokyo Metropolitan Institute of Gerontology   (Japan)

Author keywords

Amyotrophic lateral sclerosis; Electron microscopy; FUS TLS; Long non coding RNA; NEAT1 2; Paraspeckle; TDP 43

Indexed keywords

LONG UNTRANSLATED RNA; NUCLEAR ENRICHED ABUNDANT TRANSCRIPT 1 2; RNA BINDING PROTEIN; UNCLASSIFIED DRUG; DNA BINDING PROTEIN; NEAT1 LONG NON-CODING RNA, HUMAN; NEAT1 LONG NON-CODING RNA, MOUSE; PROTEIN BINDING; PROTEIN TDP-43;

AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; CELL NUCLEUS INCLUSION BODY; CELLULAR DISTRIBUTION; COILED BODY; CONTROLLED STUDY; CROSS LINKING; ELECTRON MICROSCOPY; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; IN SITU HYBRIDIZATION; MOTONEURON; PARASPECKLE; PRIORITY JOURNAL; RNA METABOLISM; ULTRAVIOLET RADIATION; AGED; ANIMAL; BIOLOGICAL MODEL; CASE CONTROL STUDY; CELL CULTURE; CELL NUCLEUS; FEMALE; HELA CELL LINE; MALE; METABOLISM; MOUSE; PATHOLOGY; SPINAL CORD; ULTRASTRUCTURE; VERY ELDERLY;

ALTERNATIVE SPLICING; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; NEOPLASMS; PROGNOSIS; RNA, LONG NONCODING; SIGNAL TRANSDUCTION; AGED; AGED, 80 AND OVER; AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; CASE-CONTROL STUDIES; CELL NUCLEUS STRUCTURES; CELLS, CULTURED; DNA-BINDING PROTEINS; FEMALE; HELA CELLS; MALE; MICE; MODELS, BIOLOGICAL; MOTOR NEURONS; PROTEIN BINDING; RNA-BINDING PROTEIN FUS; SPINAL CORD;

EID: 84879811291     PISSN: None     EISSN: 17566606     Source Type: Journal    
DOI: 10.1186/1756-6606-6-31     Document Type: Article

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