-
1
-
-
0029965803
-
The protease inhibitor, N-acetyl-l-leucyl-l-leucyl-leucyl-l-norleucinal, decreases the pool of major histocompatibility complex class I-binding peptides and inhibits peptide trimming in the endoplasmic reticulum
-
Hughes EA, Ortmann B, Surman M, Cresswell P. The protease inhibitor, N-acetyl-l-leucyl-l-leucyl-leucyl-l-norleucinal, decreases the pool of major histocompatibility complex class I-binding peptides and inhibits peptide trimming in the endoplasmic reticulum. J Exp Med (1996) 183(4):1569-78. doi:10.1084/jem.183.4.1569
-
(1996)
J Exp Med
, vol.183
, Issue.4
, pp. 1569-1578
-
-
Hughes, E.A.1
Ortmann, B.2
Surman, M.3
Cresswell, P.4
-
2
-
-
0035873704
-
26S proteasomes and immunoproteasomes produce mainly N-extended versions of an antigenic peptide
-
Cascio P, Hilton C, Kisselev AF, Rock KL, Goldberg AL. 26S proteasomes and immunoproteasomes produce mainly N-extended versions of an antigenic peptide. EMBO J (2001) 20(10):2357-66. doi:10.1093/emboj/20.10.2357
-
(2001)
EMBO J
, vol.20
, Issue.10
, pp. 2357-2366
-
-
Cascio, P.1
Hilton, C.2
Kisselev, A.F.3
Rock, K.L.4
Goldberg, A.L.5
-
3
-
-
0033525086
-
The sizes of peptides generated from protein by mammalian 26 and 20 S proteasomes. Implications for understanding the degradative mechanism and antigen presentation
-
Kisselev AF, Akopian TN, Woo KM, Goldberg AL. The sizes of peptides generated from protein by mammalian 26 and 20 S proteasomes. Implications for understanding the degradative mechanism and antigen presentation. J Biol Chem (1999) 274(6):3363-71. doi:10.1074/jbc.274.6.3363
-
(1999)
J Biol Chem
, vol.274
, Issue.6
, pp. 3363-3371
-
-
Kisselev, A.F.1
Akopian, T.N.2
Woo, K.M.3
Goldberg, A.L.4
-
4
-
-
0036902105
-
An IFN-gamma-induced aminopeptidase in the ER, ERAP1, trims precursors to MHC class I-presented peptides
-
Saric T, Chang SC, Hattori A, York IA, Markant S, Rock KL, et al. An IFN-gamma-induced aminopeptidase in the ER, ERAP1, trims precursors to MHC class I-presented peptides. Nat Immunol (2002) 3(12):1169-76. doi:10.1038/ni859
-
(2002)
Nat Immunol
, vol.3
, Issue.12
, pp. 1169-1176
-
-
Saric, T.1
Chang, S.C.2
Hattori, A.3
York, I.A.4
Markant, S.5
Rock, K.L.6
-
5
-
-
0037015624
-
ERAAP customizes peptides for MHC class I molecules in the endoplasmic reticulum
-
Serwold T, Gonzalez F, Kim J, Jacob R, Shastri N. ERAAP customizes peptides for MHC class I molecules in the endoplasmic reticulum. Nature (2002) 419(6906):480-3. doi:10.1038/nature01074
-
(2002)
Nature
, vol.419
, Issue.6906
, pp. 480-483
-
-
Serwold, T.1
Gonzalez, F.2
Kim, J.3
Jacob, R.4
Shastri, N.5
-
6
-
-
0036884090
-
The ER aminopeptidase ERAP1 enhances or limits antigen presentation by trimming epitopes to 8-9 residues
-
York IA, Chang SC, Saric T, Keys JA, Favreau JM, Goldberg AL, et al. The ER aminopeptidase ERAP1 enhances or limits antigen presentation by trimming epitopes to 8-9 residues. Nat Immunol (2002) 3(12):1177-84. doi:10.1038/ni860
-
(2002)
Nat Immunol
, vol.3
, Issue.12
, pp. 1177-1184
-
-
York, I.A.1
Chang, S.C.2
Saric, T.3
Keys, J.A.4
Favreau, J.M.5
Goldberg, A.L.6
-
7
-
-
26244455510
-
Mechanisms of MHC class I-restricted antigen processing and cross-presentation
-
Cresswell P, Ackerman AL, Giodini A, Peaper DR, Wearsch PA. Mechanisms of MHC class I-restricted antigen processing and cross-presentation. Immunol Rev (2005) 207:145-57. doi:10.1111/j.0105-2896.2005.00320.x
-
(2005)
Immunol Rev
, vol.207
, pp. 145-157
-
-
Cresswell, P.1
Ackerman, A.L.2
Giodini, A.3
Peaper, D.R.4
Wearsch, P.A.5
-
8
-
-
34548736008
-
Recent advances in antigen processing and presentation
-
Jensen PE. Recent advances in antigen processing and presentation. Nat Immunol (2007) 8(10):1041-8. doi:10.1038/ni1516
-
(2007)
Nat Immunol
, vol.8
, Issue.10
, pp. 1041-1048
-
-
Jensen, P.E.1
-
9
-
-
1042278905
-
Proteasome and peptidase function in MHC-class-I-mediated antigen presentation
-
Kloetzel PM, Ossendorp F. Proteasome and peptidase function in MHC-class-I-mediated antigen presentation. Curr Opin Immunol (2004) 16(1):76-81. doi:10.1016/j.coi.2003.11.004
-
(2004)
Curr Opin Immunol
, vol.16
, Issue.1
, pp. 76-81
-
-
Kloetzel, P.M.1
Ossendorp, F.2
-
10
-
-
82255164138
-
Towards a systems understanding of MHC class I and MHC class II antigen presentation
-
Neefjes J, Jongsma ML, Paul P, Bakke O. Towards a systems understanding of MHC class I and MHC class II antigen presentation. Nat Rev Immunol (2011) 11(12):823-36. doi:10.1038/nri3084
-
(2011)
Nat Rev Immunol
, vol.11
, Issue.12
, pp. 823-836
-
-
Neefjes, J.1
Jongsma, M.L.2
Paul, P.3
Bakke, O.4
-
11
-
-
73949158437
-
Proteases in MHC class I presentation and cross-presentation
-
Rock KL, Farfan-Arribas DJ, Shen L. Proteases in MHC class I presentation and cross-presentation. J Immunol (2010) 184(1):9-15. doi:10.4049/jimmunol.0903399
-
(2010)
J Immunol
, vol.184
, Issue.1
, pp. 9-15
-
-
Rock, K.L.1
Farfan-Arribas, D.J.2
Shen, L.3
-
12
-
-
48749092592
-
The known unknowns of antigen processing and presentation
-
Vyas JM, Van der Veen AG, Ploegh HL. The known unknowns of antigen processing and presentation. Nat Rev Immunol (2008) 8(8):607-18. doi:10.1038/nri2368
-
(2008)
Nat Rev Immunol
, vol.8
, Issue.8
, pp. 607-618
-
-
Vyas, J.M.1
Van der Veen, A.G.2
Ploegh, H.L.3
-
13
-
-
0033548055
-
A giant protease with potential to substitute for some functions of the proteasome
-
Geier E, Pfeifer G, Wilm M, Lucchiari-Hartz M, Baumeister W, Eichmann K, et al. A giant protease with potential to substitute for some functions of the proteasome. Science (1999) 283(5404):978-81. doi:10.1126/science.283.5404.978
-
(1999)
Science
, vol.283
, Issue.5404
, pp. 978-981
-
-
Geier, E.1
Pfeifer, G.2
Wilm, M.3
Lucchiari-Hartz, M.4
Baumeister, W.5
Eichmann, K.6
-
14
-
-
0032499199
-
A proteolytic system that compensates for loss of proteasome function
-
Glas R, Bogyo M, McMaster JS, Gaczynska M, Ploegh HL. A proteolytic system that compensates for loss of proteasome function. Nature (1998) 392(6676):618-22. doi:10.1038/33443
-
(1998)
Nature
, vol.392
, Issue.6676
, pp. 618-622
-
-
Glas, R.1
Bogyo, M.2
McMaster, J.S.3
Gaczynska, M.4
Ploegh, H.L.5
-
15
-
-
78650310807
-
Antigen processing by nardilysin and thimet oligopeptidase generates cytotoxic T cell epitopes
-
Kessler JH, Khan S, Seifert U, Le Gall S, Chow KM, Paschen A, et al. Antigen processing by nardilysin and thimet oligopeptidase generates cytotoxic T cell epitopes. Nat Immunol (2011) 12(1):45-53. doi:10.1038/ni.1974
-
(2011)
Nat Immunol
, vol.12
, Issue.1
, pp. 45-53
-
-
Kessler, J.H.1
Khan, S.2
Seifert, U.3
Le Gall, S.4
Chow, K.M.5
Paschen, A.6
-
16
-
-
0034730126
-
Integration of the ubiquitin-proteasome pathway with a cytosolic oligopeptidase activity
-
Wang EW, Kessler BM, Borodovsky A, Cravatt BF, Bogyo M, Ploegh HL, et al. Integration of the ubiquitin-proteasome pathway with a cytosolic oligopeptidase activity. Proc Natl Acad Sci U S A (2000) 97(18):9990-5. doi:10.1073/pnas.180328897
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, Issue.18
, pp. 9990-9995
-
-
Wang, E.W.1
Kessler, B.M.2
Borodovsky, A.3
Cravatt, B.F.4
Bogyo, M.5
Ploegh, H.L.6
-
17
-
-
0037386260
-
An essential role for tripeptidyl peptidase in the generation of an MHC class I epitope
-
Seifert U, Maranon C, Shmueli A, Desoutter JF, Wesoloski L, Janek K, et al. An essential role for tripeptidyl peptidase in the generation of an MHC class I epitope. Nat Immunol (2003) 4(4):375-9. doi:10.1038/ni905
-
(2003)
Nat Immunol
, vol.4
, Issue.4
, pp. 375-379
-
-
Seifert, U.1
Maranon, C.2
Shmueli, A.3
Desoutter, J.F.4
Wesoloski, L.5
Janek, K.6
-
18
-
-
77951298520
-
Production of an antigenic peptide by insulin-degrading enzyme
-
Parmentier N, Stroobant V, Colau D, de Diesbach P, Morel S, Chapiro J, et al. Production of an antigenic peptide by insulin-degrading enzyme. Nat Immunol (2010) 11(5):449-54. doi:10.1038/ni.1862
-
(2010)
Nat Immunol
, vol.11
, Issue.5
, pp. 449-454
-
-
Parmentier, N.1
Stroobant, V.2
Colau, D.3
de Diesbach, P.4
Morel, S.5
Chapiro, J.6
-
19
-
-
1842785206
-
A major role for TPPII in trimming proteasomal degradation products for MHC class I antigen presentation
-
Reits E, Neijssen J, Herberts C, Benckhuijsen W, Janssen L, Drijfhout JW, et al. A major role for TPPII in trimming proteasomal degradation products for MHC class I antigen presentation. Immunity (2004) 20(4):495-506. doi:10.1016/S1074-7613(04)00074-3
-
(2004)
Immunity
, vol.20
, Issue.4
, pp. 495-506
-
-
Reits, E.1
Neijssen, J.2
Herberts, C.3
Benckhuijsen, W.4
Janssen, L.5
Drijfhout, J.W.6
-
20
-
-
8744237281
-
Pathway for degradation of peptides generated by proteasomes: a key role for thimet oligopeptidase and other metallopeptidases
-
Saric T, Graef CI, Goldberg AL. Pathway for degradation of peptides generated by proteasomes: a key role for thimet oligopeptidase and other metallopeptidases. J Biol Chem (2004) 279(45):46723-32. doi:10.1074/jbc.M406537200
-
(2004)
J Biol Chem
, vol.279
, Issue.45
, pp. 46723-46732
-
-
Saric, T.1
Graef, C.I.2
Goldberg, A.L.3
-
21
-
-
84863613174
-
The efficiency of human cytomegalovirus pp65(495-503) CD8+ T cell epitope generation is determined by the balanced activities of cytosolic and endoplasmic reticulum-resident peptidases
-
Urban S, Textoris-Taube K, Reimann B, Janek K, Dannenberg T, Ebstein F, et al. The efficiency of human cytomegalovirus pp65(495-503) CD8+ T cell epitope generation is determined by the balanced activities of cytosolic and endoplasmic reticulum-resident peptidases. J Immunol (2012) 189(2):529-38. doi:10.4049/jimmunol.1101886
-
(2012)
J Immunol
, vol.189
, Issue.2
, pp. 529-538
-
-
Urban, S.1
Textoris-Taube, K.2
Reimann, B.3
Janek, K.4
Dannenberg, T.5
Ebstein, F.6
-
22
-
-
0037341473
-
The cytosolic endopeptidase, thimet oligopeptidase, destroys antigenic peptides and limits the extent of MHC class I antigen presentation
-
York IA, Mo AX, Lemerise K, Zeng W, Shen Y, Abraham CR, et al. The cytosolic endopeptidase, thimet oligopeptidase, destroys antigenic peptides and limits the extent of MHC class I antigen presentation. Immunity (2003) 18(3):429-40. doi:10.1016/S1074-7613(03)00058-X
-
(2003)
Immunity
, vol.18
, Issue.3
, pp. 429-440
-
-
York, I.A.1
Mo, A.X.2
Lemerise, K.3
Zeng, W.4
Shen, Y.5
Abraham, C.R.6
-
23
-
-
0033281074
-
The translocon: a dynamic gateway at the ER membrane
-
Johnson AE, van Waes MA. The translocon: a dynamic gateway at the ER membrane. Annu Rev Cell Dev Biol (1999) 15:799-842. doi:10.1146/annurev.cellbio.15.1.799
-
(1999)
Annu Rev Cell Dev Biol
, vol.15
, pp. 799-842
-
-
Johnson, A.E.1
van Waes, M.A.2
-
24
-
-
0030222331
-
Approaching the mechanism of protein transport across the ER membrane
-
Rapoport TA, Rolls MM, Jungnickel B. Approaching the mechanism of protein transport across the ER membrane. Curr Opin Cell Biol (1996) 8(4):499-504. doi:10.1016/S0955-0674(96)80027-5
-
(1996)
Curr Opin Cell Biol
, vol.8
, Issue.4
, pp. 499-504
-
-
Rapoport, T.A.1
Rolls, M.M.2
Jungnickel, B.3
-
25
-
-
0032189258
-
Signal sequences: more than just greasy peptides
-
Martoglio B, Dobberstein B. Signal sequences: more than just greasy peptides. Trends Cell Biol (1998) 8(10):410-5. doi:10.1016/S0962-8924(98)01360-9
-
(1998)
Trends Cell Biol
, vol.8
, Issue.10
, pp. 410-415
-
-
Martoglio, B.1
Dobberstein, B.2
-
26
-
-
0030998468
-
The chemistry and enzymology of the type I signal peptidases
-
Dalbey RE, Lively MO, Bron S, van Dijl JM. The chemistry and enzymology of the type I signal peptidases. Protein Sci (1997) 6(6):1129-38. doi:10.1002/pro.5560060601
-
(1997)
Protein Sci
, vol.6
, Issue.6
, pp. 1129-1138
-
-
Dalbey, R.E.1
Lively, M.O.2
Bron, S.3
van Dijl, J.M.4
-
27
-
-
0037150672
-
Identification of signal peptide peptidase, a presenilin-type aspartic protease
-
Weihofen A, Binns K, Lemberg MK, Ashman K, Martoglio B. Identification of signal peptide peptidase, a presenilin-type aspartic protease. Science (2002) 296(5576):2215-8. doi:10.1126/science.1070925
-
(2002)
Science
, vol.296
, Issue.5576
, pp. 2215-2218
-
-
Weihofen, A.1
Binns, K.2
Lemberg, M.K.3
Ashman, K.4
Martoglio, B.5
-
28
-
-
0029143719
-
Signal sequence processing in rough microsomes
-
Lyko F, Martoglio B, Jungnickel B, Rapoport TA, Dobberstein B. Signal sequence processing in rough microsomes. J Biol Chem (1995) 270(34):19873-8. doi:10.1074/jbc.270.34.19873
-
(1995)
J Biol Chem
, vol.270
, Issue.34
, pp. 19873-19878
-
-
Lyko, F.1
Martoglio, B.2
Jungnickel, B.3
Rapoport, T.A.4
Dobberstein, B.5
-
29
-
-
0034613193
-
Release of signal peptide fragments into the cytosol requires cleavage in the transmembrane region by a protease activity that is specifically blocked by a novel cysteine protease inhibitor
-
Weihofen A, Lemberg MK, Ploegh HL, Bogyo M, Martoglio B. Release of signal peptide fragments into the cytosol requires cleavage in the transmembrane region by a protease activity that is specifically blocked by a novel cysteine protease inhibitor. J Biol Chem (2000) 275(40):30951-6. doi:10.1074/jbc.M005980200
-
(2000)
J Biol Chem
, vol.275
, Issue.40
, pp. 30951-30956
-
-
Weihofen, A.1
Lemberg, M.K.2
Ploegh, H.L.3
Bogyo, M.4
Martoglio, B.5
-
30
-
-
0028034194
-
Identification of a Tap-dependent leader peptide recognized by alloreactive T cells specific for a class Ib antigen
-
Aldrich CJ, DeCloux A, Woods AS, Cotter RJ, Soloski MJ, Forman J. Identification of a Tap-dependent leader peptide recognized by alloreactive T cells specific for a class Ib antigen. Cell (1994) 79(4):649-58. doi:10.1016/0092-8674(94)90550-9
-
(1994)
Cell
, vol.79
, Issue.4
, pp. 649-658
-
-
Aldrich, C.J.1
DeCloux, A.2
Woods, A.S.3
Cotter, R.J.4
Soloski, M.J.5
Forman, J.6
-
31
-
-
0141594937
-
Requirement of the proteasome for the trimming of signal peptide-derived epitopes presented by the nonclassical major histocompatibility complex class I molecule HLA-E
-
Bland FA, Lemberg MK, McMichael AJ, Martoglio B, Braud VM. Requirement of the proteasome for the trimming of signal peptide-derived epitopes presented by the nonclassical major histocompatibility complex class I molecule HLA-E. J Biol Chem (2003) 278(36):33747-52. doi:10.1074/jbc.M305593200
-
(2003)
J Biol Chem
, vol.278
, Issue.36
, pp. 33747-33752
-
-
Bland, F.A.1
Lemberg, M.K.2
McMichael, A.J.3
Martoglio, B.4
Braud, V.M.5
-
32
-
-
0030988540
-
The human major histocompatibility complex class Ib molecule HLA-E binds signal sequence-derived peptides with primary anchor residues at positions 2 and 9
-
Braud V, Jones EY, McMichael A. The human major histocompatibility complex class Ib molecule HLA-E binds signal sequence-derived peptides with primary anchor residues at positions 2 and 9. Eur J Immunol (1997) 27(5):1164-9. doi:10.1002/eji.1830270517
-
(1997)
Eur J Immunol
, vol.27
, Issue.5
, pp. 1164-1169
-
-
Braud, V.1
Jones, E.Y.2
McMichael, A.3
-
33
-
-
0032524965
-
HLA-E surface expression depends on binding of TAP-dependent peptides derived from certain HLA class I signal sequences
-
Lee N, Goodlett DR, Ishitani A, Marquardt H, Geraghty DE. HLA-E surface expression depends on binding of TAP-dependent peptides derived from certain HLA class I signal sequences. J Immunol (1998) 160(10):4951-60.
-
(1998)
J Immunol
, vol.160
, Issue.10
, pp. 4951-4960
-
-
Lee, N.1
Goodlett, D.R.2
Ishitani, A.3
Marquardt, H.4
Geraghty, D.E.5
-
34
-
-
20644439105
-
MHC class Ib molecules bridge innate and acquired immunity
-
Rodgers JR, Cook RG. MHC class Ib molecules bridge innate and acquired immunity. Nat Rev Immunol (2005) 5:459-71. doi:10.1038/nri1635
-
(2005)
Nat Rev Immunol
, vol.5
, pp. 459-471
-
-
Rodgers, J.R.1
Cook, R.G.2
-
35
-
-
33846263503
-
The varicellovirus-encoded TAP inhibitor UL49.5 regulates the presentation of CTL epitopes by Qa-1b1
-
van Hall T, Laban S, Koppers-Lalic D, Koch J, Precup C, Asmawidjaja P, et al. The varicellovirus-encoded TAP inhibitor UL49.5 regulates the presentation of CTL epitopes by Qa-1b1. J Immunol (2007) 178(2):657-62. doi:10.4049/jimmunol.178.2.657
-
(2007)
J Immunol
, vol.178
, Issue.2
, pp. 657-662
-
-
van Hall, T.1
Laban, S.2
Koppers-Lalic, D.3
Koch, J.4
Precup, C.5
Asmawidjaja, P.6
-
36
-
-
77958085762
-
The other Janus face of Qa-1 and HLA-E: diverse peptide repertoires in times of stress
-
van Hall T, Oliveira CC, Joosten SA, Ottenhoff TH. The other Janus face of Qa-1 and HLA-E: diverse peptide repertoires in times of stress. Microbes Infect (2010) 12(12-13):910-8. doi:10.1016/j.micinf.2010.07.011
-
(2010)
Microbes Infect
, vol.12
, Issue.12-13
, pp. 910-918
-
-
van Hall, T.1
Oliveira, C.C.2
Joosten, S.A.3
Ottenhoff, T.H.4
-
37
-
-
0026521557
-
HLA-A2.1-associated peptides from a mutant cell line: a second pathway of antigen presentation
-
Henderson RA, Michel H, Sakaguchi K, Shabanowitz J, Appella E, Hunt DF, et al. HLA-A2.1-associated peptides from a mutant cell line: a second pathway of antigen presentation. Science (1992) 255:1264-6. doi:10.1126/science.1546329
-
(1992)
Science
, vol.255
, pp. 1264-1266
-
-
Henderson, R.A.1
Michel, H.2
Sakaguchi, K.3
Shabanowitz, J.4
Appella, E.5
Hunt, D.F.6
-
38
-
-
0026576422
-
HLA-A2 molecules in an antigen-processing mutant cell contain signal sequence-derived peptides
-
Wei ML, Cresswell P. HLA-A2 molecules in an antigen-processing mutant cell contain signal sequence-derived peptides. Nature (1992) 356:443-6. doi:10.1038/356443a0
-
(1992)
Nature
, vol.356
, pp. 443-446
-
-
Wei, M.L.1
Cresswell, P.2
-
39
-
-
10944270703
-
Consensus analysis of signal peptide peptidase and homologous human aspartic proteases reveals opposite topology of catalytic domains compared with presenilins
-
Friedmann E, Lemberg MK, Weihofen A, Dev KK, Dengler U, Rovelli G, et al. Consensus analysis of signal peptide peptidase and homologous human aspartic proteases reveals opposite topology of catalytic domains compared with presenilins. J Biol Chem (2004) 279(49):50790-8. doi:10.1074/jbc.M407898200
-
(2004)
J Biol Chem
, vol.279
, Issue.49
, pp. 50790-50798
-
-
Friedmann, E.1
Lemberg, M.K.2
Weihofen, A.3
Dev, K.K.4
Dengler, U.5
Rovelli, G.6
-
40
-
-
84885092137
-
Mechanism, specificity, and physiology of signal peptide peptidase (SPP) and SPP-like proteases
-
Voss M, Schroder B, Fluhrer R. Mechanism, specificity, and physiology of signal peptide peptidase (SPP) and SPP-like proteases. Biochim Biophys Acta (2013) 1828(12):2828-39. doi:10.1016/j.bbamem.2013.03.033
-
(2013)
Biochim Biophys Acta
, vol.1828
, Issue.12
, pp. 2828-2839
-
-
Voss, M.1
Schroder, B.2
Fluhrer, R.3
-
41
-
-
84856874999
-
The alpha-helical content of the transmembrane domain of the British dementia protein-2 (Bri2) determines its processing by signal peptide peptidase-like 2b (SPPL2b)
-
Fluhrer R, Martin L, Klier B, Haug-Kroper M, Grammer G, Nuscher B, et al. The alpha-helical content of the transmembrane domain of the British dementia protein-2 (Bri2) determines its processing by signal peptide peptidase-like 2b (SPPL2b). J Biol Chem (2012) 287(7):5156-63. doi:10.1074/jbc.M111.328104
-
(2012)
J Biol Chem
, vol.287
, Issue.7
, pp. 5156-5163
-
-
Fluhrer, R.1
Martin, L.2
Klier, B.3
Haug-Kroper, M.4
Grammer, G.5
Nuscher, B.6
-
42
-
-
0036809216
-
Requirements for signal peptide peptidase-catalyzed intramembrane proteolysis
-
Lemberg MK, Martoglio B. Requirements for signal peptide peptidase-catalyzed intramembrane proteolysis. Mol Cell (2002) 10(4):735-44. doi:10.1016/S1097-2765(02)00655-X
-
(2002)
Mol Cell
, vol.10
, Issue.4
, pp. 735-744
-
-
Lemberg, M.K.1
Martoglio, B.2
-
43
-
-
1942436343
-
On the mechanism of SPP-catalysed intramembrane proteolysis; conformational control of peptide bond hydrolysis in the plane of the membrane
-
Lemberg MK, Martoglio B. On the mechanism of SPP-catalysed intramembrane proteolysis; conformational control of peptide bond hydrolysis in the plane of the membrane. FEBS Lett (2004) 564(3):213-8. doi:10.1016/S0014-5793(04)00192-9
-
(2004)
FEBS Lett
, vol.564
, Issue.3
, pp. 213-218
-
-
Lemberg, M.K.1
Martoglio, B.2
-
44
-
-
84864391185
-
Structural analysis of hepatitis C virus core-E1 signal peptide and requirements for cleavage of the genotype 3a signal sequence by signal peptide peptidase
-
Oehler V, Filipe A, Montserret R, da Costa D, Brown G, Penin F, et al. Structural analysis of hepatitis C virus core-E1 signal peptide and requirements for cleavage of the genotype 3a signal sequence by signal peptide peptidase. J Virol (2012) 86(15):7818-28. doi:10.1128/JVI.00457-12
-
(2012)
J Virol
, vol.86
, Issue.15
, pp. 7818-7828
-
-
Oehler, V.1
Filipe, A.2
Montserret, R.3
da Costa, D.4
Brown, G.5
Penin, F.6
-
45
-
-
47749084704
-
Maturation of hepatitis C virus core protein by signal peptide peptidase is required for virus production
-
Targett-Adams P, Hope G, Boulant S, McLauchlan J. Maturation of hepatitis C virus core protein by signal peptide peptidase is required for virus production. J Biol Chem (2008) 283(24):16850-9. doi:10.1074/jbc.M802273200
-
(2008)
J Biol Chem
, vol.283
, Issue.24
, pp. 16850-16859
-
-
Targett-Adams, P.1
Hope, G.2
Boulant, S.3
McLauchlan, J.4
-
46
-
-
33749406620
-
Signal peptide peptidase cleavage of GB virus B core protein is required for productive infection in vivo
-
Targett-Adams P, Schaller T, Hope G, Lanford RE, Lemon SM, Martin A, et al. Signal peptide peptidase cleavage of GB virus B core protein is required for productive infection in vivo. J Biol Chem (2006) 281(39):29221-7. doi:10.1074/jbc.M605373200
-
(2006)
J Biol Chem
, vol.281
, Issue.39
, pp. 29221-29227
-
-
Targett-Adams, P.1
Schaller, T.2
Hope, G.3
Lanford, R.E.4
Lemon, S.M.5
Martin, A.6
-
47
-
-
79960918054
-
The crystal structure of GXGD membrane protease FlaK
-
Hu J, Xue Y, Lee S, Ha Y. The crystal structure of GXGD membrane protease FlaK. Nature (2011) 475(7357):528-31. doi:10.1038/nature10218
-
(2011)
Nature
, vol.475
, Issue.7357
, pp. 528-531
-
-
Hu, J.1
Xue, Y.2
Lee, S.3
Ha, Y.4
-
48
-
-
84871725890
-
Structure of a presenilin family intramembrane aspartate protease
-
Li X, Dang S, Yan C, Gong X, Wang J, Shi Y. Structure of a presenilin family intramembrane aspartate protease. Nature (2013) 493(7430):56-61. doi:10.1038/nature11801
-
(2013)
Nature
, vol.493
, Issue.7430
, pp. 56-61
-
-
Li, X.1
Dang, S.2
Yan, C.3
Gong, X.4
Wang, J.5
Shi, Y.6
-
49
-
-
84861532390
-
Crystal structure of Bacillus subtilis signal peptide peptidase A
-
Nam SE, Kim AC, Paetzel M. Crystal structure of Bacillus subtilis signal peptide peptidase A. J Mol Biol (2012) 419(5):347-58. doi:10.1016/j.jmb.2012.03.020
-
(2012)
J Mol Biol
, vol.419
, Issue.5
, pp. 347-358
-
-
Nam, S.E.1
Kim, A.C.2
Paetzel, M.3
-
50
-
-
84890532542
-
Structure of signal peptide peptidase A with C-termini bound in the active sites: insights into specificity, self-processing, and regulation
-
Nam SE, Paetzel M. Structure of signal peptide peptidase A with C-termini bound in the active sites: insights into specificity, self-processing, and regulation. Biochemistry (2013) 52(49):8811-22. doi:10.1021/bi4011489
-
(2013)
Biochemistry
, vol.52
, Issue.49
, pp. 8811-8822
-
-
Nam, S.E.1
Paetzel, M.2
-
51
-
-
84904560883
-
Three-dimensional structure of human gamma-secretase
-
Lu P, Bai XC, Ma D, Xie T, Yan C, Sun L, et al. Three-dimensional structure of human gamma-secretase. Nature (2014) 512(7513):166-70. doi:10.1038/nature13567
-
(2014)
Nature
, vol.512
, Issue.7513
, pp. 166-170
-
-
Lu, P.1
Bai, X.C.2
Ma, D.3
Xie, T.4
Yan, C.5
Sun, L.6
-
52
-
-
84885445749
-
New role of signal peptide peptidase to liberate C-terminal peptides for MHC class I presentation
-
Oliveira CC, Querido B, Sluijter M, de Groot AF, van der Zee R, Rabelink MJ, et al. New role of signal peptide peptidase to liberate C-terminal peptides for MHC class I presentation. J Immunol (2013) 191(8):4020-8. doi:10.4049/jimmunol.1301496
-
(2013)
J Immunol
, vol.191
, Issue.8
, pp. 4020-4028
-
-
Oliveira, C.C.1
Querido, B.2
Sluijter, M.3
de Groot, A.F.4
van der Zee, R.5
Rabelink, M.J.6
-
53
-
-
80054894761
-
Peptide transporter TAP mediates between competing antigen sources generating distinct surface MHC class I peptide repertoires
-
Oliveira CC, Querido B, Sluijter M, Derbinski J, van der Burg SH, van Hall T. Peptide transporter TAP mediates between competing antigen sources generating distinct surface MHC class I peptide repertoires. Eur J Immunol (2011) 41(11):3114-24. doi:10.1002/eji.201141836
-
(2011)
Eur J Immunol
, vol.41
, Issue.11
, pp. 3114-3124
-
-
Oliveira, C.C.1
Querido, B.2
Sluijter, M.3
Derbinski, J.4
van der Burg, S.H.5
van Hall, T.6
-
54
-
-
77953561361
-
Mammalian ceramide synthases
-
Levy M, Futerman AH. Mammalian ceramide synthases. IUBMB Life (2010) 62(5):347-56. doi:10.1002/iub.319
-
(2010)
IUBMB Life
, vol.62
, Issue.5
, pp. 347-356
-
-
Levy, M.1
Futerman, A.H.2
-
55
-
-
0242353271
-
Two mammalian longevity assurance gene (LAG1) family members, trh1 and trh4, regulate dihydroceramide synthesis using different fatty acyl-CoA donors
-
Riebeling C, Allegood JC, Wang E, Merrill AH Jr, Futerman AH. Two mammalian longevity assurance gene (LAG1) family members, trh1 and trh4, regulate dihydroceramide synthesis using different fatty acyl-CoA donors. J Biol Chem (2003) 278(44):43452-9. doi:10.1074/jbc.M307104200
-
(2003)
J Biol Chem
, vol.278
, Issue.44
, pp. 43452-43459
-
-
Riebeling, C.1
Allegood, J.C.2
Wang, E.3
Merrill A.H, Jr.4
Futerman, A.H.5
-
56
-
-
33645749031
-
Selective cytotoxic T-lymphocyte targeting of tumor immune escape variants
-
Van Hall T, Wolpert EZ, Van Veelen P, Laban S, Van der Veer M, Roseboom M, et al. Selective cytotoxic T-lymphocyte targeting of tumor immune escape variants. Nat Med (2006) 12:417-24. doi:10.1038/nm1381
-
(2006)
Nat Med
, vol.12
, pp. 417-424
-
-
Van Hall, T.1
Wolpert, E.Z.2
Van Veelen, P.3
Laban, S.4
Van der Veer, M.5
Roseboom, M.6
-
57
-
-
77951226758
-
Signal peptide peptidase (SPP) assembles with substrates and misfolded membrane proteins into distinct oligomeric complexes
-
Schrul B, Kapp K, Sinning I, Dobberstein B. Signal peptide peptidase (SPP) assembles with substrates and misfolded membrane proteins into distinct oligomeric complexes. Biochem J (2010) 427(3):523-34. doi:10.1042/BJ20091005
-
(2010)
Biochem J
, vol.427
, Issue.3
, pp. 523-534
-
-
Schrul, B.1
Kapp, K.2
Sinning, I.3
Dobberstein, B.4
-
58
-
-
33745207334
-
Signal peptide peptidase is required for dislocation from the endoplasmic reticulum
-
Loureiro J, Lilley BN, Spooner E, Noriega V, Tortorella D, Ploegh HL. Signal peptide peptidase is required for dislocation from the endoplasmic reticulum. Nature (2006) 441(7095):894-7. doi:10.1038/nature04830
-
(2006)
Nature
, vol.441
, Issue.7095
, pp. 894-897
-
-
Loureiro, J.1
Lilley, B.N.2
Spooner, E.3
Noriega, V.4
Tortorella, D.5
Ploegh, H.L.6
-
59
-
-
84900018251
-
A high-coverage shRNA screen identifies TMEM129 as an E3 ligase involved in ER-associated protein degradation
-
van de Weijer ML, Bassik MC, Luteijn RD, Voorburg CM, Lohuis MA, Kremmer E, et al. A high-coverage shRNA screen identifies TMEM129 as an E3 ligase involved in ER-associated protein degradation. Nat Commun (2014) 5:3832. doi:10.1038/ncomms4832
-
(2014)
Nat Commun
, vol.5
, pp. 3832
-
-
van de Weijer, M.L.1
Bassik, M.C.2
Luteijn, R.D.3
Voorburg, C.M.4
Lohuis, M.A.5
Kremmer, E.6
-
60
-
-
0029915568
-
The human cytomegalovirus US11 gene product dislocates MHC class I heavy chains from the endoplasmic reticulum to the cytosol
-
Wiertz EJ, Jones TR, Sun L, Bogyo M, Geuze HJ, Ploegh HL. The human cytomegalovirus US11 gene product dislocates MHC class I heavy chains from the endoplasmic reticulum to the cytosol. Cell (1996) 84(5):769-79. doi:10.1016/S0092-8674(00)81054-5
-
(1996)
Cell
, vol.84
, Issue.5
, pp. 769-779
-
-
Wiertz, E.J.1
Jones, T.R.2
Sun, L.3
Bogyo, M.4
Geuze, H.J.5
Ploegh, H.L.6
-
61
-
-
84878244523
-
Interactome analyses of mature gamma-secretase complexes reveal distinct molecular environments of presenilin (PS) paralogs and preferential binding of signal peptide peptidase to PS2
-
Jeon AH, Bohm C, Chen F, Huo H, Ruan X, Ren CH, et al. Interactome analyses of mature gamma-secretase complexes reveal distinct molecular environments of presenilin (PS) paralogs and preferential binding of signal peptide peptidase to PS2. J Biol Chem (2013) 288(21):15352-66. doi:10.1074/jbc.M112.441840
-
(2013)
J Biol Chem
, vol.288
, Issue.21
, pp. 15352-15366
-
-
Jeon, A.H.1
Bohm, C.2
Chen, F.3
Huo, H.4
Ruan, X.5
Ren, C.H.6
-
62
-
-
77952585182
-
ER quality control in the biogenesis of MHC class I molecules
-
Chapman DC, Williams DB. ER quality control in the biogenesis of MHC class I molecules. Semin Cell Dev Biol (2010) 21(5):512-9. doi:10.1016/j.semcdb.2009.12.013
-
(2010)
Semin Cell Dev Biol
, vol.21
, Issue.5
, pp. 512-519
-
-
Chapman, D.C.1
Williams, D.B.2
-
63
-
-
3042616595
-
A membrane protein required for dislocation of misfolded proteins from the ER
-
Lilley BN, Ploegh HL. A membrane protein required for dislocation of misfolded proteins from the ER. Nature (2004) 429(6994):834-40. doi:10.1038/nature02592
-
(2004)
Nature
, vol.429
, Issue.6994
, pp. 834-840
-
-
Lilley, B.N.1
Ploegh, H.L.2
-
64
-
-
0035988010
-
The HCMV gene products US2 and US11 target MHC class I molecules for degradation in the cytosol
-
van der Wal FJ, Kikkert M, Wiertz E. The HCMV gene products US2 and US11 target MHC class I molecules for degradation in the cytosol. Curr Top Microbiol Immunol (2002) 269:37-55.
-
(2002)
Curr Top Microbiol Immunol
, vol.269
, pp. 37-55
-
-
van der Wal, F.J.1
Kikkert, M.2
Wiertz, E.3
-
65
-
-
84922219279
-
Signal peptide peptidase functions in ERAD to cleave the unfolded protein response regulator XBP1u
-
Chen CY, Malchus NS, Hehn B, Stelzer W, Avci D, Langosch D, et al. Signal peptide peptidase functions in ERAD to cleave the unfolded protein response regulator XBP1u. EMBO J (2014) 33(21):2492-506. doi:10.15252/embj.201488208
-
(2014)
EMBO J
, vol.33
, Issue.21
, pp. 2492-2506
-
-
Chen, C.Y.1
Malchus, N.S.2
Hehn, B.3
Stelzer, W.4
Avci, D.5
Langosch, D.6
-
66
-
-
82355181557
-
The unfolded protein response (UPR)-activated transcription factor X-box-binding protein 1 (XBP1) induces microRNA-346 expression that targets the human antigen peptide transporter 1 (TAP1) mRNA and governs immune regulatory genes
-
Bartoszewski R, Brewer JW, Rab A, Crossman DK, Bartoszewska S, Kapoor N, et al. The unfolded protein response (UPR)-activated transcription factor X-box-binding protein 1 (XBP1) induces microRNA-346 expression that targets the human antigen peptide transporter 1 (TAP1) mRNA and governs immune regulatory genes. J Biol Chem (2011) 286(48):41862-70. doi:10.1074/jbc.M111.304956
-
(2011)
J Biol Chem
, vol.286
, Issue.48
, pp. 41862-41870
-
-
Bartoszewski, R.1
Brewer, J.W.2
Rab, A.3
Crossman, D.K.4
Bartoszewska, S.5
Kapoor, N.6
-
67
-
-
33947220268
-
Stimulation of an unfolded protein response impairs MHC class I expression
-
de Almeida SF, Fleming JV, Azevedo JE, Carmo-Fonseca M, de Sousa M. Stimulation of an unfolded protein response impairs MHC class I expression. J Immunol (2007) 178(6):3612-9. doi:10.4049/jimmunol.178.6.3612
-
(2007)
J Immunol
, vol.178
, Issue.6
, pp. 3612-3619
-
-
de Almeida, S.F.1
Fleming, J.V.2
Azevedo, J.E.3
Carmo-Fonseca, M.4
de Sousa, M.5
-
68
-
-
84255169603
-
Defining human ERAD networks through an integrative mapping strategy
-
Christianson JC, Olzmann JA, Shaler TA, Sowa ME, Bennett EJ, Richter CM, et al. Defining human ERAD networks through an integrative mapping strategy. Nat Cell Biol (2012) 14(1):93-105. doi:10.1038/ncb2383
-
(2012)
Nat Cell Biol
, vol.14
, Issue.1
, pp. 93-105
-
-
Christianson, J.C.1
Olzmann, J.A.2
Shaler, T.A.3
Sowa, M.E.4
Bennett, E.J.5
Richter, C.M.6
-
69
-
-
1842407159
-
Two novel routes of transporter associated with antigen processing (TAP)-independent major histocompatibility complex class I antigen processing
-
Snyder HL, Bacik I, Bennink JR, Kearns G, Behrens TW, Bachi T, et al. Two novel routes of transporter associated with antigen processing (TAP)-independent major histocompatibility complex class I antigen processing. J Exp Med (1997) 186(7):1087-98. doi:10.1084/jem.186.7.1087
-
(1997)
J Exp Med
, vol.186
, Issue.7
, pp. 1087-1098
-
-
Snyder, H.L.1
Bacik, I.2
Bennink, J.R.3
Kearns, G.4
Behrens, T.W.5
Bachi, T.6
-
70
-
-
15644375065
-
Promiscuous liberation of MHC-class I-binding peptides from the C termini of membrane and soluble proteins in the secretory pathway
-
Snyder HL, Bacik I, Yewdell JW, Behrens TW, Bennink JR. Promiscuous liberation of MHC-class I-binding peptides from the C termini of membrane and soluble proteins in the secretory pathway. Eur J Immunol (1998) 28(4):1339-46. doi:10.1002/(SICI)1521-4141(199804)28:04<1339::AID-IMMU1339>3.0.CO;2-B
-
(1998)
Eur J Immunol
, vol.28
, Issue.4
, pp. 1339-1346
-
-
Snyder, H.L.1
Bacik, I.2
Yewdell, J.W.3
Behrens, T.W.4
Bennink, J.R.5
-
71
-
-
0028096715
-
Trimming of antigenic peptides in an early secretory compartment
-
Snyder HL, Yewdell JW, Bennink JR. Trimming of antigenic peptides in an early secretory compartment. J Exp Med (1994) 180(6):2389-94. doi:10.1084/jem.180.6.2389
-
(1994)
J Exp Med
, vol.180
, Issue.6
, pp. 2389-2394
-
-
Snyder, H.L.1
Yewdell, J.W.2
Bennink, J.R.3
-
72
-
-
0031937894
-
TAP-independent delivery of antigenic peptides to the endoplasmic reticulum: therapeutic potential and insights into TAP-dependent antigen processing
-
Yewdell JW, Snyder HL, Bacik I, Anton LC, Deng Y, Behrens TW, et al. TAP-independent delivery of antigenic peptides to the endoplasmic reticulum: therapeutic potential and insights into TAP-dependent antigen processing. J Immunother (1998) 21:127-31. doi:10.1097/00002371-199803000-00006
-
(1998)
J Immunother
, vol.21
, pp. 127-131
-
-
Yewdell, J.W.1
Snyder, H.L.2
Bacik, I.3
Anton, L.C.4
Deng, Y.5
Behrens, T.W.6
-
73
-
-
0037242017
-
Peptide diffusion, protection, and degradation in nuclear and cytoplasmic compartments before antigen presentation by MHC class I
-
Reits E, Griekspoor A, Neijssen J, Groothuis T, Jalink K, van Veelen P, et al. Peptide diffusion, protection, and degradation in nuclear and cytoplasmic compartments before antigen presentation by MHC class I. Immunity (2003) 18(1):97-108. doi:10.1016/S1074-7613(02)00511-3
-
(2003)
Immunity
, vol.18
, Issue.1
, pp. 97-108
-
-
Reits, E.1
Griekspoor, A.2
Neijssen, J.3
Groothuis, T.4
Jalink, K.5
van Veelen, P.6
-
74
-
-
0032555922
-
Major histocompatibility complex class I viral antigen processing in the secretory pathway defined by the trans-Golgi network protease furin
-
Gil-Torregrosa BC, Raul Castano A, Del Val M. Major histocompatibility complex class I viral antigen processing in the secretory pathway defined by the trans-Golgi network protease furin. J Exp Med (1998) 188(6):1105-16. doi:10.1084/jem.188.6.1105
-
(1998)
J Exp Med
, vol.188
, Issue.6
, pp. 1105-1116
-
-
Gil-Torregrosa, B.C.1
Raul Castano, A.2
Del Val, M.3
-
75
-
-
70449713909
-
Furin-processed antigens targeted to the secretory route elicit functional TAP1-/-CD8+ T lymphocytes in vivo
-
Medina F, Ramos M, Iborra S, de Leon P, Rodriguez-Castro M, Del Val M. Furin-processed antigens targeted to the secretory route elicit functional TAP1-/-CD8+ T lymphocytes in vivo. J Immunol (2009) 183(7):4639-47. doi:10.4049/jimmunol.0901356
-
(2009)
J Immunol
, vol.183
, Issue.7
, pp. 4639-4647
-
-
Medina, F.1
Ramos, M.2
Iborra, S.3
de Leon, P.4
Rodriguez-Castro, M.5
Del Val, M.6
-
76
-
-
0036791359
-
Furin at the cutting edge: from protein traffic to embryogenesis and disease
-
Thomas G. Furin at the cutting edge: from protein traffic to embryogenesis and disease. Nat Rev Mol Cell Biol (2002) 3(10):753-66. doi:10.1038/nrm934
-
(2002)
Nat Rev Mol Cell Biol
, vol.3
, Issue.10
, pp. 753-766
-
-
Thomas, G.1
-
77
-
-
84881238159
-
The multifaceted proprotein convertases: their unique, redundant, complementary, and opposite functions
-
Seidah NG, Sadr MS, Chretien M, Mbikay M. The multifaceted proprotein convertases: their unique, redundant, complementary, and opposite functions. J Biol Chem (2013) 288(30):21473-81. doi:10.1074/jbc.R113.481549
-
(2013)
J Biol Chem
, vol.288
, Issue.30
, pp. 21473-21481
-
-
Seidah, N.G.1
Sadr, M.S.2
Chretien, M.3
Mbikay, M.4
-
78
-
-
43049141452
-
The activation and physiological functions of the proprotein convertases
-
Seidah NG, Mayer G, Zaid A, Rousselet E, Nassoury N, Poirier S, et al. The activation and physiological functions of the proprotein convertases. Int J Biochem Cell Biol (2008) 40(6-7):1111-25. doi:10.1016/j.biocel.2008.01.030
-
(2008)
Int J Biochem Cell Biol
, vol.40
, Issue.6-7
, pp. 1111-1125
-
-
Seidah, N.G.1
Mayer, G.2
Zaid, A.3
Rousselet, E.4
Nassoury, N.5
Poirier, S.6
-
79
-
-
79959547680
-
Furin is the major processing enzyme of the cardiac-specific growth factor bone morphogenetic protein 10
-
Susan-Resiga D, Essalmani R, Hamelin J, Asselin MC, Benjannet S, Chamberland A, et al. Furin is the major processing enzyme of the cardiac-specific growth factor bone morphogenetic protein 10. J Biol Chem (2011) 286(26):22785-94. doi:10.1074/jbc.M111.233577
-
(2011)
J Biol Chem
, vol.286
, Issue.26
, pp. 22785-22794
-
-
Susan-Resiga, D.1
Essalmani, R.2
Hamelin, J.3
Asselin, M.C.4
Benjannet, S.5
Chamberland, A.6
-
80
-
-
69249215352
-
Proteolytic activation of the spike protein at a novel RRRR/S motif is implicated in furin-dependent entry, syncytium formation, and infectivity of coronavirus infectious bronchitis virus in cultured cells
-
Yamada Y, Liu DX. Proteolytic activation of the spike protein at a novel RRRR/S motif is implicated in furin-dependent entry, syncytium formation, and infectivity of coronavirus infectious bronchitis virus in cultured cells. J Virol (2009) 83(17):8744-58. doi:10.1128/JVI.00613-09
-
(2009)
J Virol
, vol.83
, Issue.17
, pp. 8744-8758
-
-
Yamada, Y.1
Liu, D.X.2
-
81
-
-
77951927648
-
Post-endoplasmic reticulum rescue of unstable MHC class I requires proprotein convertase PC7
-
Leonhardt RM, Fiegl D, Rufer E, Karger A, Bettin B, Knittler MR. Post-endoplasmic reticulum rescue of unstable MHC class I requires proprotein convertase PC7. J Immunol (2010) 184(6):2985-98. doi:10.4049/jimmunol.0900308
-
(2010)
J Immunol
, vol.184
, Issue.6
, pp. 2985-2998
-
-
Leonhardt, R.M.1
Fiegl, D.2
Rufer, E.3
Karger, A.4
Bettin, B.5
Knittler, M.R.6
-
82
-
-
33749642346
-
Description of HLA class I- and CD8-deficient patients: insights into the function of cytotoxic T lymphocytes and NK cells in host defense
-
Cerundolo V, de la Salle H. Description of HLA class I- and CD8-deficient patients: insights into the function of cytotoxic T lymphocytes and NK cells in host defense. Semin Immunol (2006) 18(6):330-6. doi:10.1016/j.smim.2006.07.006
-
(2006)
Semin Immunol
, vol.18
, Issue.6
, pp. 330-336
-
-
Cerundolo, V.1
de la Salle, H.2
-
83
-
-
27644538518
-
Clinical and immunological aspects of HLA class I deficiency
-
Zimmer J, Andres E, Donato L, Hanau D, Hentges F, de la Salle H. Clinical and immunological aspects of HLA class I deficiency. QJM (2005) 98(10):719-27. doi:10.1093/qjmed/hci112
-
(2005)
QJM
, vol.98
, Issue.10
, pp. 719-727
-
-
Zimmer, J.1
Andres, E.2
Donato, L.3
Hanau, D.4
Hentges, F.5
de la Salle, H.6
-
84
-
-
0031569976
-
Human peptide transporter deficiency: importance of HLA-B in the presentation of TAP-independent EBV antigens
-
de la Salle H, Houssaint E, Peyrat MA, Arnold D, Salamero J, Pinczon D, et al. Human peptide transporter deficiency: importance of HLA-B in the presentation of TAP-independent EBV antigens. J Immunol (1997) 158(10):4555-63.
-
(1997)
J Immunol
, vol.158
, Issue.10
, pp. 4555-4563
-
-
de la Salle, H.1
Houssaint, E.2
Peyrat, M.A.3
Arnold, D.4
Salamero, J.5
Pinczon, D.6
-
85
-
-
0028300485
-
Positive selection of self- and alloreactive CD8+ T cells in TAP-1 mutant mice
-
Aldrich CJ, Ljunggren HG, Van Kaer L, Ashton-Tickardt PG, Tonegawa S, Forman J. Positive selection of self- and alloreactive CD8+ T cells in TAP-1 mutant mice. Proc Natl Acad Sci U S A (1994) 91:6525-8. doi:10.1073/pnas.91.14.6525
-
(1994)
Proc Natl Acad Sci U S A
, vol.91
, pp. 6525-6528
-
-
Aldrich, C.J.1
Ljunggren, H.G.2
Van Kaer, L.3
Ashton-Tickardt, P.G.4
Tonegawa, S.5
Forman, J.6
-
86
-
-
0030049563
-
TAP1-deficient mice select a CD8+ T cell repertoire that displays both diversity and peptide specificity
-
Sandberg JK, Chambers BJ, Van Kaer L, Karre K, Ljunggren HG. TAP1-deficient mice select a CD8+ T cell repertoire that displays both diversity and peptide specificity. Eur J Immunol (1996) 26:288-93. doi:10.1002/eji.1830260203
-
(1996)
Eur J Immunol
, vol.26
, pp. 288-293
-
-
Sandberg, J.K.1
Chambers, B.J.2
Van Kaer, L.3
Karre, K.4
Ljunggren, H.G.5
-
87
-
-
0027050452
-
TAP1 mutant mice are deficient in antigen presentation, surface class I molecules, and CD4-8+ T cells
-
Van Kaer L, Ashton-Rickardt PG, Ploegh HL, Tonegawa S. TAP1 mutant mice are deficient in antigen presentation, surface class I molecules, and CD4-8+ T cells. Cell (1992) 71(7):1205-14. doi:10.1016/S0092-8674(05)80068-6
-
(1992)
Cell
, vol.71
, Issue.7
, pp. 1205-1214
-
-
Van Kaer, L.1
Ashton-Rickardt, P.G.2
Ploegh, H.L.3
Tonegawa, S.4
-
88
-
-
0030774985
-
Generation of CD8+ T cells specific for transporter associated with antigen processing deficient cells
-
Wolpert EZ, Petersson M, Chambers BJ, Sandberg JK, Kiessling R, Ljunggren HG, et al. Generation of CD8+ T cells specific for transporter associated with antigen processing deficient cells. Proc Natl Acad Sci U S A (1997) 94(21):11496-501. doi:10.1073/pnas.94.21.11496
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, Issue.21
, pp. 11496-11501
-
-
Wolpert, E.Z.1
Petersson, M.2
Chambers, B.J.3
Sandberg, J.K.4
Kiessling, R.5
Ljunggren, H.G.6
-
89
-
-
84864936907
-
Alternative peptide repertoire of HLA-E reveals a binding motif that is strikingly similar to HLA-A2
-
Lampen MH, Hassan C, Sluijter M, Geluk A, Dijkman K, Tjon JM, et al. Alternative peptide repertoire of HLA-E reveals a binding motif that is strikingly similar to HLA-A2. Mol Immunol (2013) 53(1-2):126-31. doi:10.1016/j.molimm.2012.07.009
-
(2013)
Mol Immunol
, vol.53
, Issue.1-2
, pp. 126-131
-
-
Lampen, M.H.1
Hassan, C.2
Sluijter, M.3
Geluk, A.4
Dijkman, K.5
Tjon, J.M.6
-
90
-
-
78650642313
-
CD8+ T cell responses against TAP-inhibited cells are readily detected in the human population
-
Lampen MH, Verweij MC, Querido B, van der Burg SH, Wiertz EJ, van Hall T. CD8+ T cell responses against TAP-inhibited cells are readily detected in the human population. J Immunol (2010) 185(11):6508-17. doi:10.4049/jimmunol.1001774
-
(2010)
J Immunol
, vol.185
, Issue.11
, pp. 6508-6517
-
-
Lampen, M.H.1
Verweij, M.C.2
Querido, B.3
van der Burg, S.H.4
Wiertz, E.J.5
van Hall, T.6
-
91
-
-
76149118757
-
The nonpolymorphic MHC Qa-1b mediates CD8+ T cell surveillance of antigen-processing defects
-
Oliveira CC, van Veelen PA, Querido B, de Ru A, Sluijter M, Laban S, et al. The nonpolymorphic MHC Qa-1b mediates CD8+ T cell surveillance of antigen-processing defects. J Exp Med (2010) 207(1):207-21. doi:10.1084/jem.20091429
-
(2010)
J Exp Med
, vol.207
, Issue.1
, pp. 207-221
-
-
Oliveira, C.C.1
van Veelen, P.A.2
Querido, B.3
de Ru, A.4
Sluijter, M.5
Laban, S.6
-
92
-
-
84861234174
-
Nonclassical MHC class Ib-restricted cytotoxic T cells monitor antigen processing in the endoplasmic reticulum
-
Nagarajan NA, Gonzalez F, Shastri N. Nonclassical MHC class Ib-restricted cytotoxic T cells monitor antigen processing in the endoplasmic reticulum. Nat Immunol (2012) 13(6):579-86. doi:10.1038/ni.2282
-
(2012)
Nat Immunol
, vol.13
, Issue.6
, pp. 579-586
-
-
Nagarajan, N.A.1
Gonzalez, F.2
Shastri, N.3
-
93
-
-
72949104779
-
Antigen presentation in the thymus for positive selection and central tolerance induction
-
Klein L, Hinterberger M, Wirnsberger G, Kyewski B. Antigen presentation in the thymus for positive selection and central tolerance induction. Nat Rev Immunol (2009) 9(12):833-44. doi:10.1038/nri2669
-
(2009)
Nat Rev Immunol
, vol.9
, Issue.12
, pp. 833-844
-
-
Klein, L.1
Hinterberger, M.2
Wirnsberger, G.3
Kyewski, B.4
-
94
-
-
0033009891
-
Selection of the T cell repertoire
-
Sebzda E, Mariathasan S, Ohteki T, Jones R, Bachmann MF, Ohashi PS. Selection of the T cell repertoire. Annu Rev Immunol (1999) 17:829-74. doi:10.1146/annurev.immunol.17.1.829
-
(1999)
Annu Rev Immunol
, vol.17
, pp. 829-874
-
-
Sebzda, E.1
Mariathasan, S.2
Ohteki, T.3
Jones, R.4
Bachmann, M.F.5
Ohashi, P.S.6
-
95
-
-
67650507153
-
The thymic medulla: a unique microenvironment for intercellular self-antigen transfer
-
Koble C, Kyewski B. The thymic medulla: a unique microenvironment for intercellular self-antigen transfer. J Exp Med (2009) 206(7):1505-13. doi:10.1084/jem.20082449
-
(2009)
J Exp Med
, vol.206
, Issue.7
, pp. 1505-1513
-
-
Koble, C.1
Kyewski, B.2
-
96
-
-
48249152590
-
Preprocalcitonin signal peptide generates a cytotoxic T lymphocyte-defined tumor epitope processed by a proteasome-independent pathway
-
El Hage F, Stroobant V, Vergnon I, Baurain JF, Echchakir H, Lazar V, et al. Preprocalcitonin signal peptide generates a cytotoxic T lymphocyte-defined tumor epitope processed by a proteasome-independent pathway. Proc Natl Acad Sci U S A (2008) 105(29):10119-24. doi:10.1073/pnas.0802753105
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, Issue.29
, pp. 10119-10124
-
-
El Hage, F.1
Stroobant, V.2
Vergnon, I.3
Baurain, J.F.4
Echchakir, H.5
Lazar, V.6
-
97
-
-
80054905817
-
Different expression levels of the TAP peptide transporter lead to recognition of different antigenic peptides by tumor-specific CTL
-
Durgeau A, El Hage F, Vergnon I, Validire P, de Montpreville V, Besse B, et al. Different expression levels of the TAP peptide transporter lead to recognition of different antigenic peptides by tumor-specific CTL. J Immunol (2011) 187(11):5532-9. doi:10.4049/jimmunol.1102060
-
(2011)
J Immunol
, vol.187
, Issue.11
, pp. 5532-5539
-
-
Durgeau, A.1
El Hage, F.2
Vergnon, I.3
Validire, P.4
de Montpreville, V.5
Besse, B.6
-
98
-
-
79953125101
-
Strategies to counteract MHC-I defects in tumors
-
Lampen MH, van Hall T. Strategies to counteract MHC-I defects in tumors. Curr Opin Immunol (2011) 23(2):293-8. doi:10.1016/j.coi.2010.12.005
-
(2011)
Curr Opin Immunol
, vol.23
, Issue.2
, pp. 293-298
-
-
Lampen, M.H.1
van Hall, T.2
-
99
-
-
84856729500
-
A novel category of antigens enabling CTL immunity to tumor escape variants: Cinderella antigens
-
Seidel UJ, Oliveira CC, Lampen MH, Hall T. A novel category of antigens enabling CTL immunity to tumor escape variants: Cinderella antigens. Cancer Immunol Immunother (2012) 61(1):119-25. doi:10.1007/s00262-011-1160-x
-
(2012)
Cancer Immunol Immunother
, vol.61
, Issue.1
, pp. 119-125
-
-
Seidel, U.J.1
Oliveira, C.C.2
Lampen, M.H.3
Hall, T.4
-
100
-
-
0036776746
-
Tapasin-the keystone of the loading complex optimizing peptide binding by MHC class I molecules in the endoplasmic reticulum
-
Momburg F, Tan P. Tapasin-the keystone of the loading complex optimizing peptide binding by MHC class I molecules in the endoplasmic reticulum. Mol Immunol (2002) 39(3-4):217-33. doi:10.1016/S0161-5890(02)00103-7
-
(2002)
Mol Immunol
, vol.39
, Issue.3-4
, pp. 217-233
-
-
Momburg, F.1
Tan, P.2
-
101
-
-
84922507289
-
The first step of peptide selection in antigen presentation by MHC class I molecules
-
Garstka MA, Fish A, Celie PH, Joosten RP, Janssen GM, Berlin I, et al. The first step of peptide selection in antigen presentation by MHC class I molecules. Proc Natl Acad Sci U S A (2015) 112(5):1505-10. doi:10.1073/pnas.1416543112
-
(2015)
Proc Natl Acad Sci U S A
, vol.112
, Issue.5
, pp. 1505-1510
-
-
Garstka, M.A.1
Fish, A.2
Celie, P.H.3
Joosten, R.P.4
Janssen, G.M.5
Berlin, I.6
-
102
-
-
49649126620
-
Features of TAP-independent MHC class I ligands revealed by quantitative mass spectrometry
-
Weinzierl AO, Rudolf D, Hillen N, Tenzer S, van Endert P, Schild H, et al. Features of TAP-independent MHC class I ligands revealed by quantitative mass spectrometry. Eur J Immunol (2008) 38(6):1503-10. doi:10.1002/eji.200838136
-
(2008)
Eur J Immunol
, vol.38
, Issue.6
, pp. 1503-1510
-
-
Weinzierl, A.O.1
Rudolf, D.2
Hillen, N.3
Tenzer, S.4
van Endert, P.5
Schild, H.6
-
103
-
-
34547121970
-
Selective loading of high-affinity peptides onto major histocompatibility complex class I molecules by the tapasin-ERp57 heterodimer
-
Wearsch PA, Cresswell P. Selective loading of high-affinity peptides onto major histocompatibility complex class I molecules by the tapasin-ERp57 heterodimer. Nat Immunol (2007) 8(8):873-81. doi:10.1038/ni1485
-
(2007)
Nat Immunol
, vol.8
, Issue.8
, pp. 873-881
-
-
Wearsch, P.A.1
Cresswell, P.2
-
104
-
-
0033049945
-
Peptide-receptive class I major histocompatibility complex molecules on TAP-deficient and wild-type cells and their roles in the processing of exogenous antigens
-
Song R, Porgador A, Harding CV. Peptide-receptive class I major histocompatibility complex molecules on TAP-deficient and wild-type cells and their roles in the processing of exogenous antigens. Immunology (1999) 97(2):316-24. doi:10.1046/j.1365-2567.1999.00759.x
-
(1999)
Immunology
, vol.97
, Issue.2
, pp. 316-324
-
-
Song, R.1
Porgador, A.2
Harding, C.V.3
-
105
-
-
0030805217
-
TAP-translocated peptides specifically bind proteins in the endoplasmic reticulum, including gp96, protein disulfide isomerase and calreticulin
-
Spee P, Neefjes J. TAP-translocated peptides specifically bind proteins in the endoplasmic reticulum, including gp96, protein disulfide isomerase and calreticulin. Eur J Immunol (1997) 27(9):2441-9. doi:10.1002/eji.1830270944
-
(1997)
Eur J Immunol
, vol.27
, Issue.9
, pp. 2441-2449
-
-
Spee, P.1
Neefjes, J.2
-
106
-
-
84888350706
-
The binding of TAPBPR and tapasin to MHC class I is mutually exclusive
-
Hermann C, Strittmatter LM, Deane JE, Boyle LH. The binding of TAPBPR and tapasin to MHC class I is mutually exclusive. J Immunol (2013) 191(11):5743-50. doi:10.4049/jimmunol.1300929
-
(2013)
J Immunol
, vol.191
, Issue.11
, pp. 5743-5750
-
-
Hermann, C.1
Strittmatter, L.M.2
Deane, J.E.3
Boyle, L.H.4
-
107
-
-
0035886881
-
Processing of a multiple membrane spanning Epstein-Barr virus protein for CD8(+) T cell recognition reveals a proteasome-dependent, transporter associated with antigen processing-independent pathway
-
Lautscham G, Mayrhofer S, Taylor G, Haigh T, Leese A, Rickinson A, et al. Processing of a multiple membrane spanning Epstein-Barr virus protein for CD8(+) T cell recognition reveals a proteasome-dependent, transporter associated with antigen processing-independent pathway. J Exp Med (2001) 194(8):1053-68. doi:10.1084/jem.194.8.1053
-
(2001)
J Exp Med
, vol.194
, Issue.8
, pp. 1053-1068
-
-
Lautscham, G.1
Mayrhofer, S.2
Taylor, G.3
Haigh, T.4
Leese, A.5
Rickinson, A.6
-
108
-
-
84864535321
-
Autophagy mediates transporter associated with antigen processing-independent presentation of viral epitopes through MHC class I pathway
-
Tey SK, Khanna R. Autophagy mediates transporter associated with antigen processing-independent presentation of viral epitopes through MHC class I pathway. Blood (2012) 120(5):994-1004. doi:10.1182/blood-2012-01-402404
-
(2012)
Blood
, vol.120
, Issue.5
, pp. 994-1004
-
-
Tey, S.K.1
Khanna, R.2
-
109
-
-
79958765451
-
Alternative pathways for MHC class I presentation: a new function for autophagy
-
Chemali M, Radtke K, Desjardins M, English L. Alternative pathways for MHC class I presentation: a new function for autophagy. Cell Mol Life Sci (2011) 68(9):1533-41. doi:10.1007/s00018-011-0660-3
-
(2011)
Cell Mol Life Sci
, vol.68
, Issue.9
, pp. 1533-1541
-
-
Chemali, M.1
Radtke, K.2
Desjardins, M.3
English, L.4
-
110
-
-
67349269904
-
Autophagy enhances the presentation of endogenous viral antigens on MHC class I molecules during HSV-1 infection
-
English L, Chemali M, Duron J, Rondeau C, Laplante A, Gingras D, et al. Autophagy enhances the presentation of endogenous viral antigens on MHC class I molecules during HSV-1 infection. Nat Immunol (2009) 10(5):480-7. doi:10.1038/ni.1720
-
(2009)
Nat Immunol
, vol.10
, Issue.5
, pp. 480-487
-
-
English, L.1
Chemali, M.2
Duron, J.3
Rondeau, C.4
Laplante, A.5
Gingras, D.6
-
111
-
-
77955146917
-
Autophagy and adaptive immunity
-
Crotzer VL, Blum JS. Autophagy and adaptive immunity. Immunology (2010) 131(1):9-17. doi:10.1111/j.1365-2567.2010.03321.x
-
(2010)
Immunology
, vol.131
, Issue.1
, pp. 9-17
-
-
Crotzer, V.L.1
Blum, J.S.2
-
112
-
-
79953153130
-
When autophagy meets viruses: a double-edged sword with functions in defense and offense
-
Kim HJ, Lee S, Jung JU. When autophagy meets viruses: a double-edged sword with functions in defense and offense. Semin Immunopathol (2010) 32(4):323-41. doi:10.1007/s00281-010-0226-8
-
(2010)
Semin Immunopathol
, vol.32
, Issue.4
, pp. 323-341
-
-
Kim, H.J.1
Lee, S.2
Jung, J.U.3
-
113
-
-
34548700796
-
Unveiling the roles of autophagy in innate and adaptive immunity
-
Levine B, Deretic V. Unveiling the roles of autophagy in innate and adaptive immunity. Nat Rev Immunol (2007) 7(10):767-77. doi:10.1038/nri2161
-
(2007)
Nat Rev Immunol
, vol.7
, Issue.10
, pp. 767-777
-
-
Levine, B.1
Deretic, V.2
-
114
-
-
33646340673
-
Autophagy and antigen presentation
-
Munz C. Autophagy and antigen presentation. Cell Microbiol (2006) 8(6):891-8. doi:10.1111/j.1462-5822.2006.00714.x
-
(2006)
Cell Microbiol
, vol.8
, Issue.6
, pp. 891-898
-
-
Munz, C.1
-
115
-
-
33750974189
-
Endoplasmic reticulum and Golgi complex: contributions to, and turnover by, autophagy
-
Mijaljica D, Prescott M, Devenish RJ. Endoplasmic reticulum and Golgi complex: contributions to, and turnover by, autophagy. Traffic (2006) 7(12):1590-5. doi:10.1111/j.1600-0854.2006.00495.x
-
(2006)
Traffic
, vol.7
, Issue.12
, pp. 1590-1595
-
-
Mijaljica, D.1
Prescott, M.2
Devenish, R.J.3
-
116
-
-
34249668329
-
Eating the endoplasmic reticulum: quality control by autophagy
-
Yorimitsu T, Klionsky DJ. Eating the endoplasmic reticulum: quality control by autophagy. Trends Cell Biol (2007) 17(6):279-85. doi:10.1016/j.tcb.2007.04.005
-
(2007)
Trends Cell Biol
, vol.17
, Issue.6
, pp. 279-285
-
-
Yorimitsu, T.1
Klionsky, D.J.2
-
117
-
-
79958760234
-
Generation of MHC class I ligands in the secretory and vesicular pathways
-
Del Val M, Iborra S, Ramos M, Lazaro S. Generation of MHC class I ligands in the secretory and vesicular pathways. Cell Mol Life Sci (2011) 68(9):1543-52. doi:10.1007/s00018-011-0661-2
-
(2011)
Cell Mol Life Sci
, vol.68
, Issue.9
, pp. 1543-1552
-
-
Del Val, M.1
Iborra, S.2
Ramos, M.3
Lazaro, S.4
-
118
-
-
40449139980
-
The itinerary of autophagosomes: from peripheral formation to kiss-and-run fusion with lysosomes
-
Jahreiss L, Menzies FM, Rubinsztein DC. The itinerary of autophagosomes: from peripheral formation to kiss-and-run fusion with lysosomes. Traffic (2008) 9(4):574-87. doi:10.1111/j.1600-0854.2008.00701.x
-
(2008)
Traffic
, vol.9
, Issue.4
, pp. 574-587
-
-
Jahreiss, L.1
Menzies, F.M.2
Rubinsztein, D.C.3
-
119
-
-
84903463031
-
Dominant contribution of the proteasome and metalloproteinases to TAP-independent MHC-I peptide repertoire
-
Oliveira CC, Sluijter M, Querido B, Ossendorp F, van der Burg SH, van Hall T. Dominant contribution of the proteasome and metalloproteinases to TAP-independent MHC-I peptide repertoire. Mol Immunol (2014) 62(1):129-36. doi:10.1016/j.molimm.2014.06.006
-
(2014)
Mol Immunol
, vol.62
, Issue.1
, pp. 129-136
-
-
Oliveira, C.C.1
Sluijter, M.2
Querido, B.3
Ossendorp, F.4
van der Burg, S.H.5
van Hall, T.6
-
120
-
-
80055101156
-
Allele-dependent processing pathways generate the endogenous human leukocyte antigen (HLA) class I peptide repertoire in transporters associated with antigen processing (TAP)-deficient cells
-
Lorente E, Garcia R, Lopez D. Allele-dependent processing pathways generate the endogenous human leukocyte antigen (HLA) class I peptide repertoire in transporters associated with antigen processing (TAP)-deficient cells. J Biol Chem (2011) 286(44):38054-9. doi:10.1074/jbc.M111.281808
-
(2011)
J Biol Chem
, vol.286
, Issue.44
, pp. 38054-38059
-
-
Lorente, E.1
Garcia, R.2
Lopez, D.3
-
121
-
-
84875422824
-
Diversity of natural self-derived ligands presented by different HLA class I molecules in transporter antigen processing-deficient cells
-
Lorente E, Infantes S, Barnea E, Beer I, Barriga A, Garcia-Medel N, et al. Diversity of natural self-derived ligands presented by different HLA class I molecules in transporter antigen processing-deficient cells. PLoS One (2013) 8(3):e59118. doi:10.1371/journal.pone.0059118
-
(2013)
PLoS One
, vol.8
, Issue.3
-
-
Lorente, E.1
Infantes, S.2
Barnea, E.3
Beer, I.4
Barriga, A.5
Garcia-Medel, N.6
-
122
-
-
34250173017
-
A transporter associated with antigen-processing independent vacuolar pathway for the MHC class I-mediated presentation of endogenous transmembrane proteins
-
Tiwari N, Garbi N, Reinheckel T, Moldenhauer G, Hammerling GJ, Momburg F. A transporter associated with antigen-processing independent vacuolar pathway for the MHC class I-mediated presentation of endogenous transmembrane proteins. J Immunol (2007) 178(12):7932-42. doi:10.4049/jimmunol.178.12.7932
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(2007)
J Immunol
, vol.178
, Issue.12
, pp. 7932-7942
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Tiwari, N.1
Garbi, N.2
Reinheckel, T.3
Moldenhauer, G.4
Hammerling, G.J.5
Momburg, F.6
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