Signal peptide peptidase (SPP) assembles with substrates and misfolded membrane proteins into distinct oligomeric complexes

Biochemical Journal

Volumn 427, Issue 3, 2010, Pages 523-534

  Schrul, Bianca ^a   Kapp, Katja ^a   Sinning, Irmgard ^a   Dobberstein, Bernhard ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

Endoplasmic reticulum quality control; Intramembrane proteolysis; Oligomeric membrane protein complex; Signal peptide peptidase (SPP)

Indexed keywords

CO-IMMUNOPRECIPITATION ASSAYS; DIFFERENT SIZES; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM QUALITY CONTROL; INTRAMEMBRANE PROTEOLYSIS; MEMBRANE PROTEIN COMPLEX; MEMBRANE PROTEINS; OLIGOMERIC COMPLEXES; PREPROTEINS; SIGNAL PEPTIDE; TYPE II;

BIOLOGICAL MEMBRANES; COMPLEXATION; CUSTOMER SATISFACTION; GENE ENCODING; PEPTIDES; QUALITY ASSURANCE; TOTAL QUALITY MANAGEMENT;

QUALITY CONTROL;

MEMBRANE PROTEIN; MUTANT PROTEIN; OLIGOMER; OPSIN; PROTEIN PRECURSOR; SIGNAL PEPTIDASE; ASPARTIC PROTEINASE; SIGNAL PEPTIDE PEPTIDASE;

ARTICLE; CATALYSIS; CONTROLLED STUDY; EMBRYO; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN ASSEMBLY; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN PROTEIN INTERACTION; PROTEIN SYNTHESIS; BIOLOGICAL MODEL; CELL LINE; GENETICS; METABOLISM; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN BINDING; TANDEM MASS SPECTROMETRY; WESTERN BLOTTING;

ASPARTIC ACID ENDOPEPTIDASES; BLOTTING, WESTERN; CELL LINE; ELECTROPHORESIS, POLYACRYLAMIDE GEL; HUMANS; IMMUNOPRECIPITATION; MEMBRANE PROTEINS; MODELS, BIOLOGICAL; OPSINS; PROTEIN BINDING; TANDEM MASS SPECTROMETRY;

EID: 77951226758     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20091005     Document Type: Article

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