Pathway for degradation of peptides generated by proteasomes: A key role for thimet oligopeptidase and other metallopeptidases

Journal of Biological Chemistry

Volumn 279, Issue 45, 2004, Pages 46723-46732

  Saric, Tomo ^a,b   Graef, Claudia I ^a,c   Goldberg, Alfred L ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF COLOGNE   (Germany)

^c BASF SE   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOLS; AMINO ACIDS; ANTIGENS; CELLS; DEGRADATION; ENZYME INHIBITION; ENZYMES; HYDROLYSIS;

CELL EXTRACT; CELLULAR PROTEINS; PROTEASOMES; THIMET OLIGOPEPTIDASE (TOP);

POLYPEPTIDES;

1,10 PHENANTHROLINE; BESTATIN; BETA CASEIN; CARBON 14; CELL EXTRACT; CYTOSOL AMINOPEPTIDASE; FLUORESCAMINE; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; METALLOPROTEINASE; PROTEASOME; THIMET OLIGOPEPTIDASE;

AMINO ACID METABOLISM; AMINO ACID SEQUENCE; ARTICLE; CATALYSIS; CELL FRACTIONATION; CYTOSOL; ENZYME ACTIVITY; ENZYME INACTIVATION; ENZYME INHIBITION; ENZYME PURIFICATION; HELA CELL; HUMAN; HUMAN CELL; HYDROLYSIS; MAJOR HISTOCOMPATIBILITY COMPLEX; PRIORITY JOURNAL; PROTEIN DEGRADATION;

AMINOPEPTIDASES; ANTIGENS; CASEINS; CATALYSIS; CHROMATOGRAPHY; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYTOSOL; ENDOPEPTIDASES; GENE LIBRARY; HELA CELLS; HUMANS; HYDROLYSIS; LEUCYL AMINOPEPTIDASE; METALLOENDOPEPTIDASES; PEPTIDES; PROTEASE INHIBITORS; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN STRUCTURE, TERTIARY; TIME FACTORS;

EID: 8744237281     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M406537200     Document Type: Article

References (65)

1. Rock, K. L., Gramm, C., Rothstein, L., Clark, K., Stein, R., Dick, L., Hwang, D., and Goldberg, A. L. (1994) Cell 78, 761-771
2. Kisselev, A. F., Akopian, T. N., and Goldberg, A. L. (1998) J. Biol. Chem. 273, 1982-1989
3. Kisselev, A. F., Akopian, T. N., Woo, K. M., and Goldberg, A. L. (1999) J. Biol. Chem. 274, 3363-3371
4. Emmerich, N. P., Nussbaum, A. K., Stevanovic, S., Priemer, M., Toes, R. E., Rammensee, H. G., and Schild, H. (2000) J. Biol. Chem. 275, 21140-21148
5. Niedermann, G., King, G., Butz, S., Birsner, U., Grimm, R., Shabanowitz, J., Hunt, D. F., and Eichmann, K. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 8572-8577
6. Rock, K. L., York, I. A., Saric, T., and Goldberg, A. L. (2002) Adv. Immunol. 80, 1-70
7. Falk, K., Rotzschke, O., and Rammensee, H. G. (1990) Nature 348, 248-251
8. Beninga, J., Rock, K. L., and Goldberg, A. L. (1998) J. Biol. Chem. 273, 18734-18742
9. Reits, E., Griekspoor, A., Neijssen, J., Groothuis, T., Jalink, K., van Veelen, P., Janssen, H., Calafat, J., Drijfhout, J. W., and Neefjes, J. (2003) Immunity 18, 97-108
10. Reits, E., Neijssen, J., Herberts, C., Benckhuijsen, W., Janssen, L., Drijfhout, J. W., and Neefjes, J. (2004) Immunity 20, 495-506
11. Tenidis, K., Waldner, M., Bernhagen, J., Fischle, W., Bergmann, M., Weber, M., Merkle, M. L., Voelter, W., Brunner, H., and Kapurniotu, A. (2000) J. Mol. Biol. 295, 1055-1071
12. Hughes, E., Burke, R. M., and Doig, A. J. (2000) J. Biol. Chem. 275, 25109-25115
13. Goldberg, A. L., Cascio, P., Saric, T., and Rock, K. L. (2002) Mol. Immunol. 39, 147-164
14. Saric, T., Beninga, J., Graef, C. I., Akopian, T. N., Rock, K. L., and Goldberg, A. L. (2001) J. Biol. Chem. 276, 36474-36481
15. York, I. A., Mo, A. X., Lemerise, K., Zeng, W., Shen, Y., Abraham, C. R., Saric, T., Goldberg, A. L., and Rock, K. L. (2003) Immunity 18, 429-440
16. Kim, S. I., Pabon, A., Swanson, T. A., and Glucksman, M. J. (2003) Biochem. J. 375, 111-120
17. Falk, K., Rotzschke, O., Stevanovic, S., Jung, G., and Rammensee, H. G. (1991) Nature 351, 290-296
18. Botbol, V., and Scornik, O. A. (1979) Proc. Natl. Acad. Sci. U. S. A. 76, 710-713
19. Botbol, V., and Scornik, O. A. (1983) J. Biol. Chem. 258, 1942-1949
20. Botbol, V., and Scornik, O. A. (1989) J. Biol. Chem. 264, 13504-13509
21. Botbol, V., and Scornik, O. A. (1991) J. Biol. Chem. 266, 2151-2157
22. Botbol, V., and Scornik, O. A. (1997) Am. J. Physiol. 273, E1149-E1157
23. Tomkinson, B. (1999) Trends Biochem. Sci. 24, 355-359
24. Seifert, U., Maranon, C., Shmueli, A., Desoutter, J. F., Wesoloski, L., Janek, K., Henklein, P., Diescher, S., Andrieu, M., de la Salle, H., Weinschenk, T., Schild, H., Laderach, D., Galy, A., Haas, G., Kloetzel, P. M., Reiss, Y., and Hosmalin, A. (2003) Nat. Immunol. 4, 375-379
25. Botbol, V., and Scornik, O. A. (1979) J. Biol. Chem. 254, 11254-11257
26. Botbol, V., and Scornik, O. A. (1985) Prog. Clin. Biol. Res. 180, 573-583
27. Kirschner, R. J., and Goldberg, A. L. (1983) J. Biol. Chem. 258, 967-976
28. Barrett, A. J., Brown, M. A., Dando, P. M., Knight, C. G., McKie, N., Rawlings, N. D., and Serizawa, A. (1995) Methods Enzymol. 248, 529-556
29. Camargo, A. C., Gomes, M. D., Reichl, A. P., Ferro, E. S., Jaechieri, S., Hirata, I. Y., and Juliano, L. (1997) Biochem. J. 324 (Pt 2), 517-522
30. Rioli, V., Gozzo, F. C., Heimann, A. S., Linardi, A., Krieger, J. E., Shida, C. S., Almeida, P. C., Hyslop, S., Eberlin, M. N., and Ferro, E. S. (2003) J. Biol. Chem. 278, 8547-8555
31. Dottavio-Martin, D., and Ravel, J. M. (1978) Anal. Biochem. 87, 562-565
32. Udenfriend, S., Stein, S., Bohlen, P., Dairman, W., Leimgruber, W., and Weigele, M. (1972) Science 178, 871-872
33. Dando, P. M., Brown, M. A., and Barrett, A. J. (1993) Biochem. J. 294, 451-457
34. Saric, T., Chang, S. C., Hattori, A., York, I. A., Markant, S., Rock, K. L., Tsujimoto, M., and Goldberg, A. L. (2002) Nat. Immunol. 3, 1169-1176
35. York, I. A., Chang, S. C., Saric, T., Keys, J. A., Favreau, J. M., Goldberg, A. L., and Rock, K. L. (2002) Nat. Immunol. 3, 1177-1184
36. Cascio, P., Hilton, C., Kisselev, A. F., Rock, K. L., and Goldberg, A. L. (2001) EMBO J. 20, 2357-2366
37. Craiu, A., Akopian, T., Goldberg, A., and Rock, K. L. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 10850-10855
38. Stoltze, L., Schirle, M., Schwarz, G., Schroter, C., Thompson, M. W., Hersh, L. B., Kalbacher, H., Stevanovic, S., Rammensee, H. G., and Schild, H. (2000) Nat. Immunol. 1, 413-418
39. Paz, P., Brouwenstijn, N., Perry, R., and Shastri, N. (1999) Immunity 11, 241-251
40. Serwold, T., Gaw, S., and Shastri, N. (2001) Nat. Immunol. 2, 644-651
41. Massarelli, E. E., Casatti, C. A., Kato, A., Camargo, A. C., Bauer, J. A., Glucksman, M. J., Roberts, J. L., Hirose, S., and Ferro, E. S. (1999) Brain Res. 851, 261-265
42. Zoghbi, H. Y., and Orr, H. T. (2000) Annu. Rev. Neurosci. 23, 217-247
43. Dick, T. P., Ruppert, T., Groettrup, M., Kloetzel, P. M., Kuehn, L., Koszinowski, U. H., Stevanovic, S., Schild, H., and Rammensee, H. G. (1996) Cell 86, 253-262
44. Camargo, A. C., Shapanka, R., and Greene, L. J. (1973) Biochemistry 12, 1838-1844
45. Carvalho, K. M., and Camargo, A. C. (1981) Biochemistry 20, 7082-7088
46. Orlowski, M., Michaud, C., and Chu, T. G. (1983) Eur. J. Biochem. 135, 81-88
47. Crack, P. J., Wu, T. J., Cummins, P. M., Ferro, E. S., Tullai, J. W., Glucksman, M. J., and Roberts, J. L. (1999) Brain Res. 835, 113-124
48. Ray, K., Hines, C. S., Coll-Rodriguez, J., and Rodgers, D. W. (2004) J. Biol. Chem.
49. Conlin, C. A., and Miller, C. G. (1995) Methods Enzymol. 248, 567-579
50. Buchler, M., Tisljar, U., and Wolf, D. H. (1994) Eur. J. Biochem. 219, 627-639
51. Wilk, S., and Orlowski, M. (1980) J. Neurochem. 35, 1172-1182
52. Wilk, S., and Orlowski, M. (1983) J. Neurochem. 40, 842-849
53. Portaro, F. C., Gomes, M. D., Cabrera, A., Fernandes, B. L., Silva, C. L., Ferro, E. S., Juliano, L., and de Camargo, A. C. (1999) Biochem. Biophys. Res. Commun. 255, 596-601
54. Silva, C. L., Portaro, F. C., Bonato, V. L., de Camargo, A. C., and Ferro, E. S. (1999) Biochem. Biophys. Res. Commun. 255, 591-595
55. Tamura, N., Lottspeich, F., Baumeister, W., and Tamura, T. (1998) Cell 95, 637-648
56. Serizawa, A., Dando, P. M., and Barrett, A. J. (1995) J. Biol. Chem. 270, 2092-2098
57. Checler, F., Barelli, H., Dauch, P., Dive, V., Vincent, B., and Vincent, J. P. (1995) Methods Enzymol. 248, 593-614
58. Oliveira, V., Araujo, M. C., Rioli, V., de Camargo, A. C., Tersariol, I. L., Juliano, M. A., Juliano, L., and Ferro, E. S. (2003) FEBS Lett. 541, 89-92
59. Kato, A., Sugiura, N., Saruta, Y., Hosoiri, T., Yasue, H., and Hirose, S. (1997) J. Biol. Chem. 272, 15313-15322
60. Rioli, V., Kato, A., Portaro, F. C., Cury, G. K., te Kaat, K., Vincent, B., Checler, F., Camargo, A. C., Glucksman, M. J., Roberts, J. L., Hirose, S., and Ferro, E. S. (1998) Biochem. Biophys. Res. Commun. 250, 5-11
61. Desautels, M., and Goldberg, A. L. (1982) Proc. Natl. Acad. Sci. U. S. A. 79, 1869-1873
62. Authier, F., Posner, B. I., and Bergeron, J. J. (1996) Clin. Investig. Med. 19, 149-160
63. Chesneau, V., Pierotti, A. R., Barre, N., Creminon, C., Tougard, C., and Cohen, P. (1994) J. Biol. Chem. 269, 2056-2061
64. Hayashi, M. A., Portaro, F. C., Tambourgi, D. V., Sucupira, M., Yamane, T., Fernandes, B. L., Ferro, E. S., Reboucas, N. A., and de Camargo, A. C. (2000) Biochem. Biophys. Res. Commun. 269, 7-13
65. Serwold, T., Gonzalez, F., Kim, J., Jacob, R., and Shastri, N. (2002) Nature 419, 480-483