The Er aminopeptidase ERAP I enhances or limits antigen presentation by trimming epitopes to 8-9 residues

Nature Immunology

Volumn 3, Issue 12, 2002, Pages 1177-1184

  York, Ian A ^a   Chang, Shih Chung ^b   Saric, Tomo ^b,c   Keys, Jennifer A ^a   Favreau, Janice M ^a   Goldberg, Alfred L ^b   Rock, Kenneth L ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c ATABIS GmbH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMINOPEPTIDASE; CALRETICULIN; EPITOPE; GAMMA INTERFERON; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; OVALBUMIN; PROTEASOME; PROTEIN ERAP; PROTEIN PRECURSOR; RNA; UNCLASSIFIED DRUG; CYTOSOL AMINOPEPTIDASE; HLA ANTIGEN CLASS 1; LIGAND; PUROMYCIN INSENSITIVE LEUCYL SPECIFIC AMINOPEPTIDASE; PUROMYCIN-INSENSITIVE LEUCYL-SPECIFIC AMINOPEPTIDASE;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANTIGEN PRESENTATION; ARTICLE; CHEMICAL MODIFICATION; CONTROLLED STUDY; CYTOSOL; ENDOPLASMIC RETICULUM; ENZYME PURIFICATION; HUMAN; HUMAN CELL; IN VIVO STUDY; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN SYNTHESIS; ANIMAL; CELL LINE; CHEMISTRY; FLOW CYTOMETRY; IMMUNOLOGY; MOLECULAR GENETICS; NON-PROGRAMMATIC; SIGNAL TRANSDUCTION;

NON-PROGRAMMATIC;

ANIMALS; ANTIGEN PRESENTATION; CELL LINE; EPITOPES; FLOW CYTOMETRY; HISTOCOMPATIBILITY ANTIGENS CLASS I; HUMANS; LEUCYL AMINOPEPTIDASE; LIGANDS; MOLECULAR SEQUENCE DATA; OVALBUMIN; SIGNAL TRANSDUCTION;

EID: 0036884090     PISSN: 15292908     EISSN: None     Source Type: Journal    
DOI: 10.1038/ni860     Document Type: Article

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