-
1
-
-
84873039983
-
Rho GTPases in platelet function
-
CrossRef PubMed
-
Aslan, J.E. and McCarty, O.J. (2013) Rho GTPases in platelet function. J. Thromb. Haemost. 11, 35-46 CrossRef PubMed
-
(2013)
J. Thromb. Haemost.
, vol.11
, pp. 35-46
-
-
Aslan, J.E.1
McCarty, O.J.2
-
2
-
-
79960638351
-
Regulating thrombus growth and stability to achieve an optimal response to injury
-
CrossRef PubMed
-
Brass, L.F., Wannemacher, K.M., Ma, P. and Stalker, T.J. (2011) Regulating thrombus growth and stability to achieve an optimal response to injury. J. Thromb. Haemost. 9, 66-75 CrossRef PubMed
-
(2011)
J. Thromb. Haemost.
, vol.9
, pp. 66-75
-
-
Brass, L.F.1
Wannemacher, K.M.2
Ma, P.3
Stalker, T.J.4
-
3
-
-
33644821104
-
What does it take to make the perfect clot?
-
CrossRef PubMed
-
Monroe, D.M. and Hoffman, M. (2006) What does it take to make the perfect clot? Arterioscler. Thromb. Vasc. Biol. 26, 41-48 CrossRef PubMed
-
(2006)
Arterioscler. Thromb. Vasc. Biol.
, vol.26
, pp. 41-48
-
-
Monroe, D.M.1
Hoffman, M.2
-
4
-
-
0026671880
-
Platelet morphologic changes and fibrinogen receptor localization. Initial responses in ADP-activated human platelets
-
PubMed
-
Hensler, M.E., Frojmovic, M., Taylor, R.G., Hantgan, R.R. and Lewis, J.C. (1992) Platelet morphologic changes and fibrinogen receptor localization. Initial responses in ADP-activated human platelets. Am. J. Pathol. 141, 707-719 PubMed
-
(1992)
Am. J. Pathol.
, vol.141
, pp. 707-719
-
-
Hensler, M.E.1
Frojmovic, M.2
Taylor, R.G.3
Hantgan, R.R.4
Lewis, J.C.5
-
5
-
-
33646565045
-
Shear induces a unique series of morphological changes in translocating platelets: Effects of morphology on translocation dynamics
-
CrossRef PubMed
-
Maxwell, M.J., Dopheide, S.M., Turner, S.J. and Jackson, S.P. (2006) Shear induces a unique series of morphological changes in translocating platelets: effects of morphology on translocation dynamics. Arterioscler. Thromb. Vasc. Biol. 26, 663-669 CrossRef PubMed
-
(2006)
Arterioscler. Thromb. Vasc. Biol.
, vol.26
, pp. 663-669
-
-
Maxwell, M.J.1
Dopheide, S.M.2
Turner, S.J.3
Jackson, S.P.4
-
6
-
-
84882591380
-
The platelet cytoskeleton
-
Michelson, A.D., ed. Academic Press, London CrossRef
-
Hartwig, J.H. (2013) The platelet cytoskeleton. In Platelets (Michelson, A.D., ed.), pp. 145-168, Academic Press, London CrossRef
-
(2013)
Platelets
, pp. 145-168
-
-
Hartwig, J.H.1
-
7
-
-
70449485000
-
Normal filopodia extension in VASP-deficient platelets upon activation by adhesive matrices or soluble agonists
-
PubMed
-
Eliautou, S., Mangin, P.H., Walter, U., Gachet, C. and Lanza, F. (2009) Normal filopodia extension in VASP-deficient platelets upon activation by adhesive matrices or soluble agonists. Thromb. Haemost. 102, 792-794 PubMed
-
(2009)
Thromb. Haemost.
, vol.102
, pp. 792-794
-
-
Eliautou, S.1
Mangin, P.H.2
Walter, U.3
Gachet, C.4
Lanza, F.5
-
8
-
-
28244479366
-
Rac1 is essential for platelet lamellipodia formation and aggregate stability under flow
-
CrossRef PubMed
-
McCarty, O.J., Larson, M.K., Auger, J.M., Kalia, N., Atkinson, B.T., Pearce, A.C., Ruf, S., Henderson, R.B., Tybulewicz, V.L., Machesky, L.M. and Watson, S.P. (2005) Rac1 is essential for platelet lamellipodia formation and aggregate stability under flow. J. Biol. Chem. 280, 39474-39484 CrossRef PubMed
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 39474-39484
-
-
McCarty, O.J.1
Larson, M.K.2
Auger, J.M.3
Kalia, N.4
Atkinson, B.T.5
Pearce, A.C.6
Ruf, S.7
Henderson, R.B.8
Tybulewicz, V.L.9
Machesky, L.M.10
Watson, S.P.11
-
9
-
-
0021330259
-
Redistribution of alpha-granules and their contents in thrombin-stimulated platelets
-
CrossRef PubMed
-
Stenberg, P.E., Shuman, M.A., Levine, S.P. and Bainton, D.F. (1984) Redistribution of alpha-granules and their contents in thrombin-stimulated platelets. J. Cell Biol. 98, 748-760 CrossRef PubMed
-
(1984)
J. Cell Biol.
, vol.98
, pp. 748-760
-
-
Stenberg, P.E.1
Shuman, M.A.2
Levine, S.P.3
Bainton, D.F.4
-
10
-
-
0023184750
-
The exocytosis of human blood platelets. A fast freezing and freeze-substitution analysis
-
PubMed
-
Morgenstern, E., Neumann, K. and Patscheke, H. (1987) The exocytosis of human blood platelets. A fast freezing and freeze-substitution analysis. Eur. J. Cell Biol. 43, 273-282 PubMed
-
(1987)
Eur. J. Cell Biol.
, vol.43
, pp. 273-282
-
-
Morgenstern, E.1
Neumann, K.2
Patscheke, H.3
-
11
-
-
0037459096
-
Membrane domains in the secretory and endocytic pathways
-
CrossRef PubMed
-
Pfeffer, S. (2003) Membrane domains in the secretory and endocytic pathways. Cell 112, 507-517 CrossRef PubMed
-
(2003)
Cell
, vol.112
, pp. 507-517
-
-
Pfeffer, S.1
-
12
-
-
0027202087
-
Identification of small GTP-binding Rab proteins in human platelets - Thrombin-induced phosphorylation of Rab3b, Rab6 and Rab8 proteins
-
CrossRef PubMed
-
Karniguian, A., Zahraoui, A. and Tavitian, A. (1993) Identification of small GTP-binding Rab proteins in human platelets - thrombin-induced phosphorylation of Rab3b, Rab6 and Rab8 proteins. Proc. Natl. Acad. Sci. U.S.A. 90, 7647-7651 CrossRef PubMed
-
(1993)
Proc. Natl. Acad. Sci. U.S.A.
, vol.90
, pp. 7647-7651
-
-
Karniguian, A.1
Zahraoui, A.2
Tavitian, A.3
-
13
-
-
0033199617
-
Rab6 is phosphorylated in thrombin-activated platelets by a protein kinase C-dependent mechanism: Effects on GTP/GDP binding and cellular distribution
-
CrossRef PubMed
-
Fitzgerald, M.L. and Reed, G.L. (1999) Rab6 is phosphorylated in thrombin-activated platelets by a protein kinase C-dependent mechanism: effects on GTP/GDP binding and cellular distribution. Biochem. J. 342, 353-360 CrossRef PubMed
-
(1999)
Biochem. J.
, vol.342
, pp. 353-360
-
-
Fitzgerald, M.L.1
Reed, G.L.2
-
14
-
-
1642275392
-
Munc13-4 is a GTP-Rab27-binding protein regulating dense core granule secretion in platelets
-
CrossRef PubMed
-
Shirakawa, R., Higashi, T., Tabuchi, A., Yoshioka, A., Nishioka, H., Fukuda, M., Kita, T. and Horiuchi, H. (2004) Munc13-4 is a GTP-Rab27-binding protein regulating dense core granule secretion in platelets. J. Biol. Chem. 279, 10730-10737 CrossRef PubMed
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 10730-10737
-
-
Shirakawa, R.1
Higashi, T.2
Tabuchi, A.3
Yoshioka, A.4
Nishioka, H.5
Fukuda, M.6
Kita, T.7
Horiuchi, H.8
-
15
-
-
84878653881
-
Platelet secretion
-
Michelson, A.D., ed. Academic Press, London CrossRef
-
Flaumenhaft, R. (2013) Platelet secretion. In Platelets (Michelson, A.D., ed.), pp. 343-366, Academic Press, London CrossRef
-
(2013)
Platelets
, pp. 343-366
-
-
Flaumenhaft, R.1
-
16
-
-
0022396633
-
Human platelet Fc receptor for immunoglobulin G. Identification as a 40,000-molecular-weight membrane protein shared by monocytes
-
CrossRef PubMed
-
Rosenfeld, S.I., Looney, R.J., Leddy, J.P., Phipps, D.C., Abraham, G.N. and Anderson, C.L. (1985) Human platelet Fc receptor for immunoglobulin G. Identification as a 40,000-molecular-weight membrane protein shared by monocytes. J. Clin. Invest. 76, 2317-2322 CrossRef PubMed
-
(1985)
J. Clin. Invest.
, vol.76
, pp. 2317-2322
-
-
Rosenfeld, S.I.1
Looney, R.J.2
Leddy, J.P.3
Phipps, D.C.4
Abraham, G.N.5
Anderson, C.L.6
-
17
-
-
3042640509
-
Expression of Toll-like receptors on human platelets
-
CrossRef PubMed
-
Shiraki, R., Inoue, N., Kawasaki, S., Takei, A., Kadotani, M., Ohnishi, Y., Ejiri, J., Kobayashi, S., Hirata, K., Kawashima, S. and Yokoyama, M. (2004) Expression of Toll-like receptors on human platelets. Thromb. Res. 113, 379-385 CrossRef PubMed
-
(2004)
Thromb. Res.
, vol.113
, pp. 379-385
-
-
Shiraki, R.1
Inoue, N.2
Kawasaki, S.3
Takei, A.4
Kadotani, M.5
Ohnishi, Y.6
Ejiri, J.7
Kobayashi, S.8
Hirata, K.9
Kawashima, S.10
Yokoyama, M.11
-
18
-
-
0034672366
-
Functional expression of CCR1, CCR3, CCR4, and CXCR4 chemokine receptors on human platelets
-
PubMed
-
Clemetson, K.J., Clemetson, J.M., Proudfoot, A.E., Power, C.A., Baggiolini, M. and Wells, T.N. (2000) Functional expression of CCR1, CCR3, CCR4, and CXCR4 chemokine receptors on human platelets. Blood 96, 4046-4054 PubMed
-
(2000)
Blood
, vol.96
, pp. 4046-4054
-
-
Clemetson, K.J.1
Clemetson, J.M.2
Proudfoot, A.E.3
Power, C.A.4
Baggiolini, M.5
Wells, T.N.6
-
19
-
-
0030859873
-
The role of platelets in antimicrobial host defense
-
CrossRef PubMed
-
Yeaman, M.R. (1997) The role of platelets in antimicrobial host defense. Clin. Infect. Dis. 25, 951-968 CrossRef PubMed
-
(1997)
Clin. Infect. Dis.
, vol.25
, pp. 951-968
-
-
Yeaman, M.R.1
-
20
-
-
0015154112
-
Platelet interaction with bacteria. I. Reaction phases and effects of inhibitors
-
PubMed
-
Clawson, C.C. and White, J.G. (1971) Platelet interaction with bacteria. I. Reaction phases and effects of inhibitors. Am. J. Pathol. 65, 367-380 PubMed
-
(1971)
Am. J. Pathol.
, vol.65
, pp. 367-380
-
-
Clawson, C.C.1
White, J.G.2
-
21
-
-
0015152169
-
Platelet interaction with bacteria. II. Fate of the bacteria
-
PubMed
-
Clawson, C.C. and White, J.G. (1971) Platelet interaction with bacteria. II. Fate of the bacteria. Am. J. Pathol. 65, 381-397 PubMed
-
(1971)
Am. J. Pathol.
, vol.65
, pp. 381-397
-
-
Clawson, C.C.1
White, J.G.2
-
22
-
-
0015592506
-
Platelet interaction with bacteria. III. Ultrastructure
-
PubMed
-
Clawson, C.C. (1973) Platelet interaction with bacteria. III. Ultrastructure. Am. J. Pathol. 70, 449-471 PubMed
-
(1973)
Am. J. Pathol.
, vol.70
, pp. 449-471
-
-
Clawson, C.C.1
-
23
-
-
0033022973
-
Antimicrobial peptides from platelets
-
CrossRef PubMed
-
Yeaman, M.R. and Bayer, A.S. (1999) Antimicrobial peptides from platelets. Drug Resist. Updat. 2, 116-126 CrossRef PubMed
-
(1999)
Drug Resist. Updat.
, vol.2
, pp. 116-126
-
-
Yeaman, M.R.1
Bayer, A.S.2
-
24
-
-
0036893696
-
Antimicrobial peptides from human platelets
-
CrossRef PubMed
-
Tang, Y.Q., Yeaman, M.R. and Selsted, M.E. (2002) Antimicrobial peptides from human platelets. Infect. Immun. 70, 6524-6533 CrossRef PubMed
-
(2002)
Infect. Immun.
, vol.70
, pp. 6524-6533
-
-
Tang, Y.Q.1
Yeaman, M.R.2
Selsted, M.E.3
-
25
-
-
33646854563
-
The interaction of bacterial pathogens with platelets
-
CrossRef PubMed
-
Fitzgerald, J.R., Foster, T.J. and Cox, D. (2006) The interaction of bacterial pathogens with platelets. Nat. Rev. Microbiol. 4, 445-457 CrossRef PubMed
-
(2006)
Nat. Rev. Microbiol.
, vol.4
, pp. 445-457
-
-
Fitzgerald, J.R.1
Foster, T.J.2
Cox, D.3
-
26
-
-
34548076553
-
Proteomic analysis of platelet alpha-granules using mass spectrometry
-
CrossRef PubMed
-
Maynard, D.M., Heijnen, H.F., Horne, M.K., White, J.G. and Gahl, W.A. (2007) Proteomic analysis of platelet alpha-granules using mass spectrometry. J. Thromb. Haemost. 5, 1945-1955 CrossRef PubMed
-
(2007)
J. Thromb. Haemost.
, vol.5
, pp. 1945-1955
-
-
Maynard, D.M.1
Heijnen, H.F.2
Horne, M.K.3
White, J.G.4
Gahl, W.A.5
-
27
-
-
12144291702
-
Characterization of the proteins released from activated platelets leads to localization of novel platelet proteins in human atherosclerotic lesions
-
CrossRef PubMed
-
Coppinger, J.A., Cagney, G., Toomey, S., Kislinger, T., Belton, O., McRedmond, J.P., Cahill, D.J., Emili, A., Fitzgerald, D.J. and Maguire, P.B. (2004) Characterization of the proteins released from activated platelets leads to localization of novel platelet proteins in human atherosclerotic lesions. Blood 103, 2096-2104 CrossRef PubMed
-
(2004)
Blood
, vol.103
, pp. 2096-2104
-
-
Coppinger, J.A.1
Cagney, G.2
Toomey, S.3
Kislinger, T.4
Belton, O.5
McRedmond, J.P.6
Cahill, D.J.7
Emili, A.8
Fitzgerald, D.J.9
Maguire, P.B.10
-
28
-
-
77957268771
-
Platelets: Pleiotropic roles in atherogenesis and atherothrombosis
-
CrossRef PubMed
-
Linden, M.D. and Jackson, D.E. (2010) Platelets: pleiotropic roles in atherogenesis and atherothrombosis. Int. J. Biochem. Cell Biol. 42, 1762-1766 CrossRef PubMed
-
(2010)
Int. J. Biochem. Cell Biol.
, vol.42
, pp. 1762-1766
-
-
Linden, M.D.1
Jackson, D.E.2
-
29
-
-
0037097809
-
Endothelial von Willebrand factor recruits platelets to atherosclerosis-prone sites in response to hypercholesterolemia
-
CrossRef PubMed
-
Theilmeier, G., Michiels, C., Spaepen, E., Vreys, I., Collen, D., Vermylen, J. and Hoylaerts, M.F. (2002) Endothelial von Willebrand factor recruits platelets to atherosclerosis-prone sites in response to hypercholesterolemia. Blood 99, 4486-4493 CrossRef PubMed
-
(2002)
Blood
, vol.99
, pp. 4486-4493
-
-
Theilmeier, G.1
Michiels, C.2
Spaepen, E.3
Vreys, I.4
Collen, D.5
Vermylen, J.6
Hoylaerts, M.F.7
-
30
-
-
0037109144
-
Engagement of glycoprotein IIb/IIIa (alpha(IIb)beta3) on platelets upregulates CD40L and triggers CD40L-dependent matrix degradation by endothelial cells
-
CrossRef PubMed
-
May, A.E., Kalsch, T., Massberg, S., Herouy, Y., Schmidt, R. and Gawaz, M. (2002) Engagement of glycoprotein IIb/IIIa (alpha(IIb)beta3) on platelets upregulates CD40L and triggers CD40L-dependent matrix degradation by endothelial cells. Circulation 106, 2111-2117 CrossRef PubMed
-
(2002)
Circulation
, vol.106
, pp. 2111-2117
-
-
May, A.E.1
Kalsch, T.2
Massberg, S.3
Herouy, Y.4
Schmidt, R.5
Gawaz, M.6
-
31
-
-
31044436262
-
Platelets in inflammation and atherogenesis
-
CrossRef PubMed
-
Gawaz, M., Langer, H. and May, A.E. (2005) Platelets in inflammation and atherogenesis. J. Clin. Invest. 115, 3378-3384 CrossRef PubMed
-
(2005)
J. Clin. Invest.
, vol.115
, pp. 3378-3384
-
-
Gawaz, M.1
Langer, H.2
May, A.E.3
-
32
-
-
84864567858
-
Platelet function and signaling in diabetes mellitus
-
CrossRef PubMed
-
Randriamboavonjy, V. and Fleming, I. (2012) Platelet function and signaling in diabetes mellitus. Curr. Vasc. Pharmacol. 10, 532-538 CrossRef PubMed
-
(2012)
Curr. Vasc. Pharmacol.
, vol.10
, pp. 532-538
-
-
Randriamboavonjy, V.1
Fleming, I.2
-
33
-
-
29244474586
-
Platelets in sepsis
-
CrossRef PubMed
-
Levi, M. (2005) Platelets in sepsis. Hematology 10, 129-131 CrossRef PubMed
-
(2005)
Hematology
, vol.10
, pp. 129-131
-
-
Levi, M.1
-
34
-
-
78650415386
-
Platelets: Linking hemostasis and cancer
-
CrossRef PubMed
-
Jain, S., Harris, J. and Ware, J. (2010) Platelets: linking hemostasis and cancer. Arterioscler. Thromb. Vasc. Biol. 30, 2362-2367 CrossRef PubMed
-
(2010)
Arterioscler. Thromb. Vasc. Biol.
, vol.30
, pp. 2362-2367
-
-
Jain, S.1
Harris, J.2
Ware, J.3
-
35
-
-
79961071855
-
Genome-wide RNA-seq analysis of human and mouse platelet transcriptomes
-
CrossRef PubMed
-
Rowley, J.W., Oler, A.J., Tolley, N.D., Hunter, B.N., Low, E.N., Nix, D.A., Yost, C.C., Zimmerman, G.A. and Weyrich, A.S. (2011) Genome-wide RNA-seq analysis of human and mouse platelet transcriptomes. Blood 118, e101-e111 CrossRef PubMed
-
(2011)
Blood
, vol.118
, pp. e101-e111
-
-
Rowley, J.W.1
Oler, A.J.2
Tolley, N.D.3
Hunter, B.N.4
Low, E.N.5
Nix, D.A.6
Yost, C.C.7
Zimmerman, G.A.8
Weyrich, A.S.9
-
36
-
-
84863011162
-
Megakaryocyte-specific RhoA deficiency causes macrothrombocytopenia and defective platelet activation in hemostasis and thrombosis
-
CrossRef PubMed
-
Pleines, I., Hagedorn, I., Gupta, S., May, F., Chakarova, L., van Hengel, J., Offermanns, S., Krohne, G., Kleinschnitz, C., Brakebusch, C. and Nieswandt, B. (2012) Megakaryocyte-specific RhoA deficiency causes macrothrombocytopenia and defective platelet activation in hemostasis and thrombosis. Blood 119, 1054-1063 CrossRef PubMed
-
(2012)
Blood
, vol.119
, pp. 1054-1063
-
-
Pleines, I.1
Hagedorn, I.2
Gupta, S.3
May, F.4
Chakarova, L.5
Van Hengel, J.6
Offermanns, S.7
Krohne, G.8
Kleinschnitz, C.9
Brakebusch, C.10
Nieswandt, B.11
-
37
-
-
77951459334
-
Multiple alterations of platelet functions dominated by increased secretion in mice lacking Cdc42 in platelets
-
CrossRef PubMed
-
Pleines, I., Eckly, A., Elvers, M., Hagedorn, I., Eliautou, S., Bender, M., Wu, X., Lanza, F., Gachet, C., Brakebusch, C. and Nieswandt, B. (2010) Multiple alterations of platelet functions dominated by increased secretion in mice lacking Cdc42 in platelets. Blood 115, 3364-3373 CrossRef PubMed
-
(2010)
Blood
, vol.115
, pp. 3364-3373
-
-
Pleines, I.1
Eckly, A.2
Elvers, M.3
Hagedorn, I.4
Eliautou, S.5
Bender, M.6
Wu, X.7
Lanza, F.8
Gachet, C.9
Brakebusch, C.10
Nieswandt, B.11
-
38
-
-
84867754221
-
The first comprehensive and quantitative analysis of human platelet protein composition allows the comparative analysis of structural and functional pathways
-
CrossRef PubMed
-
Burkhart, J.M., Vaudel, M., Gambaryan, S., Radau, S., Walter, U., Martens, L., Geiger, J., Sickmann, A. and Zahedi, R.P. (2012) The first comprehensive and quantitative analysis of human platelet protein composition allows the comparative analysis of structural and functional pathways. Blood 120, e73-e82 CrossRef PubMed
-
(2012)
Blood
, vol.120
, pp. e73-e82
-
-
Burkhart, J.M.1
Vaudel, M.2
Gambaryan, S.3
Radau, S.4
Walter, U.5
Martens, L.6
Geiger, J.7
Sickmann, A.8
Zahedi, R.P.9
-
39
-
-
59849108084
-
Rac1 is essential for phospholipase C-gamma2 activation in platelets
-
CrossRef PubMed
-
Pleines, I., Elvers, M., Strehl, A., Pozgajova, M., Varga-Szabo, D., May, F., Chrostek-Grashoff, A., Brakebusch, C. and Nieswandt, B. (2009) Rac1 is essential for phospholipase C-gamma2 activation in platelets. Pflugers Arch. 457, 1173-1185 CrossRef PubMed
-
(2009)
Pflugers Arch.
, vol.457
, pp. 1173-1185
-
-
Pleines, I.1
Elvers, M.2
Strehl, A.3
Pozgajova, M.4
Varga-Szabo, D.5
May, F.6
Chrostek-Grashoff, A.7
Brakebusch, C.8
Nieswandt, B.9
-
40
-
-
0028338545
-
Activation of phosphoinositide 3-kinase activity by Cdc42Hs binding to p85
-
PubMed
-
Zheng, Y., Bagrodia, S. and Cerione, R.A. (1994) Activation of phosphoinositide 3-kinase activity by Cdc42Hs binding to p85. J. Biol. Chem. 269, 18727-18730 PubMed
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 18727-18730
-
-
Zheng, Y.1
Bagrodia, S.2
Cerione, R.A.3
-
41
-
-
0030570801
-
Interaction of the Rho family small G proteins with kinectin, an anchoring protein of kinesin motor
-
CrossRef PubMed
-
Hotta, K., Tanaka, K., Mino, A., Kohno, H. and Takai, Y. (1996) Interaction of the Rho family small G proteins with kinectin, an anchoring protein of kinesin motor. Biochem. Biophys. Res. Commun. 225, 69-74 CrossRef PubMed
-
(1996)
Biochem. Biophys. Res. Commun.
, vol.225
, pp. 69-74
-
-
Hotta, K.1
Tanaka, K.2
Mino, A.3
Kohno, H.4
Takai, Y.5
-
42
-
-
0033373784
-
Cell adhesion and Rho small GTPases
-
PubMed
-
Fukata, M., Nakagawa, M., Kuroda, S. and Kaibuchi, K. (1999) Cell adhesion and Rho small GTPases. J. Cell Sci. 112, 4491-4500 PubMed
-
(1999)
J. Cell Sci.
, vol.112
, pp. 4491-4500
-
-
Fukata, M.1
Nakagawa, M.2
Kuroda, S.3
Kaibuchi, K.4
-
43
-
-
34447648178
-
Genetic and pharmacologic evidence that Rac1 GTPase is involved in regulation of platelet secretion and aggregation
-
CrossRef PubMed
-
Akbar, H., Kim, J., Funk, K., Cancelas, J.A., Shang, X., Chen, L., Johnson, J.F., Williams, D.A. and Zheng, Y. (2007) Genetic and pharmacologic evidence that Rac1 GTPase is involved in regulation of platelet secretion and aggregation. J. Thromb. Haemost. 5, 1747-1755 CrossRef PubMed
-
(2007)
J. Thromb. Haemost.
, vol.5
, pp. 1747-1755
-
-
Akbar, H.1
Kim, J.2
Funk, K.3
Cancelas, J.A.4
Shang, X.5
Chen, L.6
Johnson, J.F.7
Williams, D.A.8
Zheng, Y.9
-
44
-
-
0034624753
-
Autoinhibition and activation mechanisms of the Wiskott-Aldrich syndrome protein
-
CrossRef PubMed
-
Kim, A.S., Kakalis, L.T., Abdul-Manan, N., Liu, G.A. and Rosen, M.K. (2000) Autoinhibition and activation mechanisms of the Wiskott-Aldrich syndrome protein. Nature 404, 151-158 CrossRef PubMed
-
(2000)
Nature
, vol.404
, pp. 151-158
-
-
Kim, A.S.1
Kakalis, L.T.2
Abdul-Manan, N.3
Liu, G.A.4
Rosen, M.K.5
-
45
-
-
0033160196
-
Cooperation between mDia1 and ROCK in Rho-induced actin reorganization
-
CrossRef PubMed
-
Watanabe, N., Kato, T., Fujita, A., Ishizaki, T. and Narumiya, S. (1999) Cooperation between mDia1 and ROCK in Rho-induced actin reorganization. Nat. Cell Biol. 1, 136-143 CrossRef PubMed
-
(1999)
Nat. Cell Biol.
, vol.1
, pp. 136-143
-
-
Watanabe, N.1
Kato, T.2
Fujita, A.3
Ishizaki, T.4
Narumiya, S.5
-
46
-
-
0033593667
-
Activation of G(12)/G(13) results in shape change and Rho/Rho-kinase-mediated myosin light chain phosphorylation in mouse platelets
-
CrossRef PubMed
-
Klages, B., Brandt, U., Simon, M.I., Schultz, G. and Offermanns, S. (1999) Activation of G(12)/G(13) results in shape change and Rho/Rho-kinase-mediated myosin light chain phosphorylation in mouse platelets. J. Cell Biol. 144, 745-754 CrossRef PubMed
-
(1999)
J. Cell Biol.
, vol.144
, pp. 745-754
-
-
Klages, B.1
Brandt, U.2
Simon, M.I.3
Schultz, G.4
Offermanns, S.5
-
47
-
-
34249855080
-
Signaling through G(alpha)13 switch region I is essential for protease-activated receptor 1-mediated human platelet shape change, aggregation, and secretion
-
CrossRef PubMed
-
Huang, J.S., Dong, L., Kozasa, T. and Le Breton, G.C. (2007) Signaling through G(alpha)13 switch region I is essential for protease-activated receptor 1-mediated human platelet shape change, aggregation, and secretion. J. Biol. Chem. 282, 10210-10222 CrossRef PubMed
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 10210-10222
-
-
Huang, J.S.1
Dong, L.2
Kozasa, T.3
Le Breton, G.C.4
-
48
-
-
0028179510
-
G proteins of the G12 family are activated via thromboxane A2 and thrombin receptors in human platelets
-
CrossRef PubMed
-
Offermanns, S., Laugwitz, K.L., Spicher, K. and Schultz, G. (1994) G proteins of the G12 family are activated via thromboxane A2 and thrombin receptors in human platelets. Proc. Natl. Acad. Sci. U.S.A. 91, 504-508 CrossRef PubMed
-
(1994)
Proc. Natl. Acad. Sci. U.S.A.
, vol.91
, pp. 504-508
-
-
Offermanns, S.1
Laugwitz, K.L.2
Spicher, K.3
Schultz, G.4
-
49
-
-
0345708272
-
G13 is an essential mediator of platelet activation in hemostasis and thrombosis
-
CrossRef PubMed
-
Moers, A., Nieswandt, B., Massberg, S., Wettschureck, N., Gruner, S., Konrad, I., Schulte, V., Aktas, B., Gratacap, M.P., Simon, M.I. et al. (2003) G13 is an essential mediator of platelet activation in hemostasis and thrombosis. Nat. Med. 9, 1418-1422 CrossRef PubMed
-
(2003)
Nat. Med.
, vol.9
, pp. 1418-1422
-
-
Moers, A.1
Nieswandt, B.2
Massberg, S.3
Wettschureck, N.4
Gruner, S.5
Konrad, I.6
Schulte, V.7
Aktas, B.8
Gratacap, M.P.9
Simon, M.I.10
-
50
-
-
0032555506
-
Thrombin inactivates myosin light chain phosphatase via Rho and its target Rho kinase in human endothelial cells
-
CrossRef PubMed
-
Essler, M., Amano, M., Kruse, H.J., Kaibuchi, K., Weber, P.C. and Aepfelbacher, M. (1998) Thrombin inactivates myosin light chain phosphatase via Rho and its target Rho kinase in human endothelial cells. J. Biol. Chem. 273, 21867-21874 CrossRef PubMed
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 21867-21874
-
-
Essler, M.1
Amano, M.2
Kruse, H.J.3
Kaibuchi, K.4
Weber, P.C.5
Aepfelbacher, M.6
-
51
-
-
78650415748
-
Signaling during platelet adhesion and activation
-
CrossRef PubMed
-
Li, Z., Delaney, M.K., O'Brien, K.A. and Du, X. (2010) Signaling during platelet adhesion and activation. Arterioscler. Thromb. Vasc. Biol. 30, 2341-2349 CrossRef PubMed
-
(2010)
Arterioscler. Thromb. Vasc. Biol.
, vol.30
, pp. 2341-2349
-
-
Li, Z.1
Delaney, M.K.2
O'Brien, K.A.3
Du, X.4
-
52
-
-
0037177816
-
RhoA sustains integrin alpha IIbbeta 3 adhesion contacts under high shear
-
PubMed
-
Schoenwaelder, S.M., Hughan, S.C., Boniface, K., Fernando, S., Holdsworth, M., Thompson, P.E., Salem, H.H. and Jackson, S.P. (2002) RhoA sustains integrin alpha IIbbeta 3 adhesion contacts under high shear. J. Biol. Chem. 277, 14738-14746 PubMed
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 14738-14746
-
-
Schoenwaelder, S.M.1
Hughan, S.C.2
Boniface, K.3
Fernando, S.4
Holdsworth, M.5
Thompson, P.E.6
Salem, H.H.7
Jackson, S.P.8
-
53
-
-
35948942682
-
A molecular switch that controls cell spreading and retraction
-
CrossRef PubMed
-
Flevaris, P., Stojanovic, A., Gong, H., Chishti, A., Welch, E. and Du, X. (2007) A molecular switch that controls cell spreading and retraction. J. Cell Biol. 179, 553-565 CrossRef PubMed
-
(2007)
J. Cell Biol.
, vol.179
, pp. 553-565
-
-
Flevaris, P.1
Stojanovic, A.2
Gong, H.3
Chishti, A.4
Welch, E.5
Du, X.6
-
54
-
-
84855897077
-
Historical overview of Rho GTPases
-
CrossRef PubMed
-
Ridley, A.J. (2012) Historical overview of Rho GTPases. Methods Mol. Biol. 827,3-12 CrossRef PubMed
-
(2012)
Methods Mol. Biol.
, vol.827
, pp. 3-12
-
-
Ridley, A.J.1
-
55
-
-
0038024241
-
Rocks: Multifunctional kinases in cell behaviour
-
CrossRef PubMed
-
Riento, K. and Ridley, A.J. (2003) Rocks: multifunctional kinases in cell behaviour. Nat. Rev. Mol. Cell. Biol. 4, 446-456 CrossRef PubMed
-
(2003)
Nat. Rev. Mol. Cell. Biol.
, vol.4
, pp. 446-456
-
-
Riento, K.1
Ridley, A.J.2
-
56
-
-
43749120730
-
Biochemical characterization of the Rho GTPase-regulated actin assembly by diaphanous-related formins, mDia1 and Daam1, in platelets
-
CrossRef PubMed
-
Higashi, T., Ikeda, T., Shirakawa, R., Kondo, H., Kawato, M., Horiguchi, M., Okuda, T., Okawa, K., Fukai, S., Nureki, O. et al. (2008) Biochemical characterization of the Rho GTPase-regulated actin assembly by diaphanous-related formins, mDia1 and Daam1, in platelets. J. Biol. Chem. 283, 8746-8755 CrossRef PubMed
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 8746-8755
-
-
Higashi, T.1
Ikeda, T.2
Shirakawa, R.3
Kondo, H.4
Kawato, M.5
Horiguchi, M.6
Okuda, T.7
Okawa, K.8
Fukai, S.9
Nureki, O.10
-
57
-
-
67349276010
-
RhoA effector mDia1 is required for PI 3-kinase-dependent actin remodeling and spreading by thrombin in platelets
-
CrossRef PubMed
-
Gao, G., Chen, L., Dong, B., Gu, H., Dong, H., Pan, Y., Gao, Y. and Chen, X. (2009) RhoA effector mDia1 is required for PI 3-kinase-dependent actin remodeling and spreading by thrombin in platelets. Biochem. Biophys. Res. Commun. 385, 439-444 CrossRef PubMed
-
(2009)
Biochem. Biophys. Res. Commun.
, vol.385
, pp. 439-444
-
-
Gao, G.1
Chen, L.2
Dong, B.3
Gu, H.4
Dong, H.5
Pan, Y.6
Gao, Y.7
Chen, X.8
-
58
-
-
50149083752
-
Mammalian Rho GTPases: New insights into their functions from in vivo studies
-
CrossRef PubMed
-
Heasman, S.J. and Ridley, A.J. (2008) Mammalian Rho GTPases: new insights into their functions from in vivo studies. Nat. Rev. Mol. Cell. Biol. 9, 690-701 CrossRef PubMed
-
(2008)
Nat. Rev. Mol. Cell. Biol.
, vol.9
, pp. 690-701
-
-
Heasman, S.J.1
Ridley, A.J.2
-
59
-
-
58049213341
-
Specificity of interactions between mDia isoforms and Rho proteins
-
CrossRef PubMed
-
Lammers, M., Meyer, S., Kuhlmann, D. and Wittinghofer, A. (2008) Specificity of interactions between mDia isoforms and Rho proteins. J. Biol. Chem. 283, 35236-35246 CrossRef PubMed
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 35236-35246
-
-
Lammers, M.1
Meyer, S.2
Kuhlmann, D.3
Wittinghofer, A.4
-
60
-
-
0037382160
-
Disruption of the diaphanous-related formin Drf1 gene encoding mDia1 reveals a role for Drf3 as an effector for Cdc42
-
CrossRef PubMed
-
Peng, J., Wallar, B.J., Flanders, A., Swiatek, P.J. and Alberts, A.S. (2003) Disruption of the diaphanous-related formin Drf1 gene encoding mDia1 reveals a role for Drf3 as an effector for Cdc42. Curr. Biol. 13, 534-545 CrossRef PubMed
-
(2003)
Curr. Biol.
, vol.13
, pp. 534-545
-
-
Peng, J.1
Wallar, B.J.2
Flanders, A.3
Swiatek, P.J.4
Alberts, A.S.5
-
61
-
-
79953885132
-
Rif-mDia1 interaction is involved in filopodium formation independent of Cdc42 and Rac effectors
-
CrossRef PubMed
-
Goh, W.I., Sudhaharan, T., Lim, K.B., Sem, K.P., Lau, C.L. and Ahmed, S. (2011) Rif-mDia1 interaction is involved in filopodium formation independent of Cdc42 and Rac effectors. J. Biol. Chem. 286, 13681-13694 CrossRef PubMed
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 13681-13694
-
-
Goh, W.I.1
Sudhaharan, T.2
Lim, K.B.3
Sem, K.P.4
Lau, C.L.5
Ahmed, S.6
-
62
-
-
84856945929
-
mDia1 and WAVE2 proteins interact directly with IRSp53 in filopodia and are involved in filopodium formation
-
CrossRef PubMed
-
Goh, W.I., Lim, K.B., Sudhaharan, T., Sem, K.P., Bu, W., Chou, A.M. and Ahmed, S. (2012) mDia1 and WAVE2 proteins interact directly with IRSp53 in filopodia and are involved in filopodium formation. J. Biol. Chem. 287, 4702-4714 CrossRef PubMed
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 4702-4714
-
-
Goh, W.I.1
Lim, K.B.2
Sudhaharan, T.3
Sem, K.P.4
Bu, W.5
Chou, A.M.6
Ahmed, S.7
-
63
-
-
77649271537
-
The role of formins in filopodia formation
-
CrossRef PubMed
-
Mellor, H. (2010) The role of formins in filopodia formation. Biochim. Biophys. Acta 1803, 191-200 CrossRef PubMed
-
(2010)
Biochim. Biophys. Acta
, vol.1803
, pp. 191-200
-
-
Mellor, H.1
-
64
-
-
26244449496
-
Cdc42 is not essential for filopodium formation, directed migration, cell polarization, and mitosis in fibroblastoid cells
-
CrossRef PubMed
-
Czuchra, A., Wu, X., Meyer, H., van Hengel, J., Schroeder, T., Geffers, R., Rottner, K. and Brakebusch, C. (2005) Cdc42 is not essential for filopodium formation, directed migration, cell polarization, and mitosis in fibroblastoid cells. Mol. Biol. Cell 16, 4473-4484 CrossRef PubMed
-
(2005)
Mol. Biol. Cell
, vol.16
, pp. 4473-4484
-
-
Czuchra, A.1
Wu, X.2
Meyer, H.3
Van Hengel, J.4
Schroeder, T.5
Geffers, R.6
Rottner, K.7
Brakebusch, C.8
-
65
-
-
12544253725
-
The Rho family GTPase Rif induces filopodia through mDia2
-
CrossRef PubMed
-
Pellegrin, S. and Mellor, H. (2005) The Rho family GTPase Rif induces filopodia through mDia2. Curr. Biol. 15, 129-133 CrossRef PubMed
-
(2005)
Curr. Biol.
, vol.15
, pp. 129-133
-
-
Pellegrin, S.1
Mellor, H.2
-
66
-
-
33846981893
-
Cdc42 and ARP2/3-independent regulation of filopodia by an integral membrane lipid-phosphatase-related protein
-
CrossRef PubMed
-
Sigal, Y.J., Quintero, O.A., Cheney, R.E. and Morris, A.J. (2007) Cdc42 and ARP2/3-independent regulation of filopodia by an integral membrane lipid-phosphatase-related protein. J. Cell Sci. 120, 340-352 CrossRef PubMed
-
(2007)
J. Cell Sci.
, vol.120
, pp. 340-352
-
-
Sigal, Y.J.1
Quintero, O.A.2
Cheney, R.E.3
Morris, A.J.4
-
67
-
-
0034142240
-
Activation of the small GTPases, rac and cdc42, after ligation of the platelet PAR-1 receptor
-
PubMed
-
Azim, A.C., Barkalow, K., Chou, J. and Hartwig, J.H. (2000) Activation of the small GTPases, rac and cdc42, after ligation of the platelet PAR-1 receptor. Blood 95, 959-964 PubMed
-
(2000)
Blood
, vol.95
, pp. 959-964
-
-
Azim, A.C.1
Barkalow, K.2
Chou, J.3
Hartwig, J.H.4
-
68
-
-
0035895076
-
Rac, a small guanosine triphosphate-binding protein, and p21-activated kinase are activated during platelet spreading on collagen-coated surfaces: Roles of integrin alpha(2)beta(1)
-
CrossRef PubMed
-
Suzuki-Inoue, K., Yatomi, Y., Asazuma, N., Kainoh, M., Tanaka, T., Satoh, K. and Ozaki, Y. (2001) Rac, a small guanosine triphosphate-binding protein, and p21-activated kinase are activated during platelet spreading on collagen-coated surfaces: roles of integrin alpha(2)beta(1). Blood 98, 3708-3716 CrossRef PubMed
-
(2001)
Blood
, vol.98
, pp. 3708-3716
-
-
Suzuki-Inoue, K.1
Yatomi, Y.2
Asazuma, N.3
Kainoh, M.4
Tanaka, T.5
Satoh, K.6
Ozaki, Y.7
-
69
-
-
0028986008
-
The association of pp125FAK, pp60Src, CDC42Hs and Rap1B with the cytoskeleton of aggregated platelets is a reversible process regulated by calcium
-
CrossRef PubMed
-
Dash, D., Aepfelbacher, M. and Siess, W. (1995) The association of pp125FAK, pp60Src, CDC42Hs and Rap1B with the cytoskeleton of aggregated platelets is a reversible process regulated by calcium. FEBS Lett. 363, 231-234 CrossRef PubMed
-
(1995)
FEBS Lett.
, vol.363
, pp. 231-234
-
-
Dash, D.1
Aepfelbacher, M.2
Siess, W.3
-
70
-
-
0028982953
-
Integrin alpha IIb beta 3-mediated translocation of CDC42Hs to the cytoskeleton in stimulated human platelets
-
CrossRef PubMed
-
Dash, D., Aepfelbacher, M. and Siess, W. (1995) Integrin alpha IIb beta 3-mediated translocation of CDC42Hs to the cytoskeleton in stimulated human platelets. J. Biol. Chem. 270, 17321-17326 CrossRef PubMed
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 17321-17326
-
-
Dash, D.1
Aepfelbacher, M.2
Siess, W.3
-
71
-
-
30544438322
-
The integrin alpha6beta1 modulation of PI3K and Cdc42 activities induces dynamic filopodium formation in human platelets
-
CrossRef PubMed
-
Chang, J.C., Chang, H.H., Lin, C.T. and Lo, S.J. (2005) The integrin alpha6beta1 modulation of PI3K and Cdc42 activities induces dynamic filopodium formation in human platelets. J. Biomed. Sci. 12, 881-898 CrossRef PubMed
-
(2005)
J. Biomed. Sci.
, vol.12
, pp. 881-898
-
-
Chang, J.C.1
Chang, H.H.2
Lin, C.T.3
Lo, S.J.4
-
72
-
-
42449153335
-
Critical roles for the actin cytoskeleton and cdc42 in regulating platelet integrin alpha2beta1
-
CrossRef PubMed
-
Pula, G. and Poole, A.W. (2008) Critical roles for the actin cytoskeleton and cdc42 in regulating platelet integrin alpha2beta1. Platelets 19, 199-210 CrossRef PubMed
-
(2008)
Platelets
, vol.19
, pp. 199-210
-
-
Pula, G.1
Poole, A.W.2
-
73
-
-
79960567744
-
Gene targeting implicates Cdc42 GTPase in GPVI and non-GPVI mediated platelet filopodia formation, secretion and aggregation
-
CrossRef PubMed
-
Akbar, H., Shang, X., Perveen, R., Berryman, M., Funk, K., Johnson, J.F., Tandon, N.N. and Zheng, Y. (2011) Gene targeting implicates Cdc42 GTPase in GPVI and non-GPVI mediated platelet filopodia formation, secretion and aggregation. PLoS One 6, e22117 CrossRef PubMed
-
(2011)
PLoS One
, vol.6
-
-
Akbar, H.1
Shang, X.2
Perveen, R.3
Berryman, M.4
Funk, K.5
Johnson, J.F.6
Tandon, N.N.7
Zheng, Y.8
-
74
-
-
84871642430
-
Lineage tracing of Pf4-Cre marks hematopoietic stem cells and their progeny
-
CrossRef PubMed
-
Calaminus, S.D., Guitart, A., Sinclair, A., Schachtner, H., Watson, S.P., Holyoake, T.L., Kranc, K.R. and Machesky, L.M. (2012) Lineage tracing of Pf4-Cre marks hematopoietic stem cells and their progeny. PLoS One 7, e51361 CrossRef PubMed
-
(2012)
PLoS One
, vol.7
-
-
Calaminus, S.D.1
Guitart, A.2
Sinclair, A.3
Schachtner, H.4
Watson, S.P.5
Holyoake, T.L.6
Kranc, K.R.7
Machesky, L.M.8
-
75
-
-
0034597539
-
The novel Rho-family GTPase rif regulates coordinated actin-based membrane rearrangements
-
CrossRef PubMed
-
Ellis, S. and Mellor, H. (2000) The novel Rho-family GTPase rif regulates coordinated actin-based membrane rearrangements. Curr. Biol. 10, 1387-1390 CrossRef PubMed
-
(2000)
Curr. Biol.
, vol.10
, pp. 1387-1390
-
-
Ellis, S.1
Mellor, H.2
-
76
-
-
33845868501
-
Evolution of the Rho family of ras-like GTPases in eukaryotes
-
CrossRef PubMed
-
Boureux, A., Vignal, E., Faure, S. and Fort, P. (2007) Evolution of the Rho family of ras-like GTPases in eukaryotes. Mol. Biol. Evol. 24, 203-216 CrossRef PubMed
-
(2007)
Mol. Biol. Evol.
, vol.24
, pp. 203-216
-
-
Boureux, A.1
Vignal, E.2
Faure, S.3
Fort, P.4
-
77
-
-
66549084876
-
A HaemAtlas: Characterizing gene expression in differentiated human blood cells
-
CrossRef PubMed
-
Watkins, N.A., Gusnanto, A., de Bono, B., De, S., Miranda-Saavedra, D., Hardie, D.L., Angenent, W.G., Attwood, A.P., Ellis, P.D., Erber, W. et al. (2009) A HaemAtlas: characterizing gene expression in differentiated human blood cells. Blood 113, e1-e9 CrossRef PubMed
-
(2009)
Blood
, vol.113
, pp. e1-e9
-
-
Watkins, N.A.1
Gusnanto, A.2
De Bono, B.3
De, S.4
Miranda-Saavedra, D.5
Hardie, D.L.6
Angenent, W.G.7
Attwood, A.P.8
Ellis, P.D.9
Erber, W.10
-
78
-
-
20044391651
-
Expression of the Rho-family GTPase gene RHOF in lymphocyte subsets and malignant lymphomas
-
CrossRef PubMed
-
Gouw, L.G., Reading, N.S., Jenson, S.D., Lim, M.S. and Elenitoba-Johnson, K.S. (2005) Expression of the Rho-family GTPase gene RHOF in lymphocyte subsets and malignant lymphomas. Br. J. Haematol. 129, 531-533 CrossRef PubMed
-
(2005)
Br. J. Haematol.
, vol.129
, pp. 531-533
-
-
Gouw, L.G.1
Reading, N.S.2
Jenson, S.D.3
Lim, M.S.4
Elenitoba-Johnson, K.S.5
-
79
-
-
0942268723
-
Rho GTPases have diverse effects on the organization of the actin filament system
-
CrossRef PubMed
-
Aspenstrom, P., Fransson, A. and Saras, J. (2004) Rho GTPases have diverse effects on the organization of the actin filament system. Biochem. J. 377, 327-337 CrossRef PubMed
-
(2004)
Biochem. J.
, vol.377
, pp. 327-337
-
-
Aspenstrom, P.1
Fransson, A.2
Saras, J.3
-
80
-
-
70450222906
-
Rif proteins take to the RhoD: Rho GTPases at the crossroads of actin dynamics and membrane trafficking
-
CrossRef PubMed
-
Gad, A.K. and Aspenstrom, P. (2010) Rif proteins take to the RhoD: Rho GTPases at the crossroads of actin dynamics and membrane trafficking. Cell Signal. 22, 183-189 CrossRef PubMed
-
(2010)
Cell Signal.
, vol.22
, pp. 183-189
-
-
Gad, A.K.1
Aspenstrom, P.2
-
81
-
-
10644249023
-
What is in a filopodium? Starfish versus hedgehogs
-
CrossRef PubMed
-
Passey, S., Pellegrin, S. and Mellor, H. (2004) What is in a filopodium? Starfish versus hedgehogs. Biochem. Soc. Trans. 32, 1115-1117 CrossRef PubMed
-
(2004)
Biochem. Soc. Trans.
, vol.32
, pp. 1115-1117
-
-
Passey, S.1
Pellegrin, S.2
Mellor, H.3
-
82
-
-
77951191158
-
The small GTPase Rif is an alternative trigger for the formation of actin stress fibers in epithelial cells
-
CrossRef PubMed
-
Fan, L., Pellegrin, S., Scott, A. and Mellor, H. (2010) The small GTPase Rif is an alternative trigger for the formation of actin stress fibers in epithelial cells. J. Cell Sci. 123, 1247-1252 CrossRef PubMed
-
(2010)
J. Cell Sci.
, vol.123
, pp. 1247-1252
-
-
Fan, L.1
Pellegrin, S.2
Scott, A.3
Mellor, H.4
-
83
-
-
19544386803
-
Structural and mechanistic insights into the interaction between Rho and mammalian Dia
-
CrossRef PubMed
-
Rose, R., Weyand, M., Lammers, M., Ishizaki, T., Ahmadian, M.R. and Wittinghofer, A. (2005) Structural and mechanistic insights into the interaction between Rho and mammalian Dia. Nature 435, 513-518 CrossRef PubMed
-
(2005)
Nature
, vol.435
, pp. 513-518
-
-
Rose, R.1
Weyand, M.2
Lammers, M.3
Ishizaki, T.4
Ahmadian, M.R.5
Wittinghofer, A.6
-
84
-
-
84869746159
-
mDia1-3 in mammalian filopodia
-
CrossRef PubMed
-
Goh, W.I. and Ahmed, S. (2012) mDia1-3 in mammalian filopodia. Commun. Integr. Biol. 5, 340-344 CrossRef PubMed
-
(2012)
Commun. Integr. Biol.
, vol.5
, pp. 340-344
-
-
Goh, W.I.1
Ahmed, S.2
-
85
-
-
84872872791
-
The small GTPase Rif is dispensable for platelet filopodia generation in mice
-
CrossRef PubMed
-
Goggs, R., Savage, J.S., Mellor, H. and Poole, A.W. (2013) The small GTPase Rif is dispensable for platelet filopodia generation in mice. PLoS One 8, e54663 CrossRef PubMed
-
(2013)
PLoS One
, vol.8
-
-
Goggs, R.1
Savage, J.S.2
Mellor, H.3
Poole, A.W.4
-
86
-
-
80051599187
-
G-protein coupled and ITAM receptor regulation of the formin FHOD1 through Rho kinase in platelets
-
CrossRef PubMed
-
Thomas, S.G., Calaminus, S.D., Machesky, L.M., Alberts, A.S. and Watson, S.P. (2011) G-protein coupled and ITAM receptor regulation of the formin FHOD1 through Rho kinase in platelets. J. Thromb. Haemost. 9, 1648-1651 CrossRef PubMed
-
(2011)
J. Thromb. Haemost.
, vol.9
, pp. 1648-1651
-
-
Thomas, S.G.1
Calaminus, S.D.2
Machesky, L.M.3
Alberts, A.S.4
Watson, S.P.5
-
87
-
-
65349085563
-
Defining mechanisms of actin polymerization and depolymerization during dendritic spine morphogenesis
-
CrossRef PubMed
-
Hotulainen, P., Llano, O., Smirnov, S., Tanhuanpaa, K., Faix, J., Rivera, C. and Lappalainen, P. (2009) Defining mechanisms of actin polymerization and depolymerization during dendritic spine morphogenesis. J. Cell Biol. 185, 323-339 CrossRef PubMed
-
(2009)
J. Cell Biol.
, vol.185
, pp. 323-339
-
-
Hotulainen, P.1
Llano, O.2
Smirnov, S.3
Tanhuanpaa, K.4
Faix, J.5
Rivera, C.6
Lappalainen, P.7
-
88
-
-
28244479373
-
Isozyme-specific stimulation of phospholipase C-gamma(2) by Rac GTPases
-
CrossRef PubMed
-
Piechulek, T., Rehlen, T., Walliser, C., Vatter, P., Moepps, B. and Gierschik, P. (2005) Isozyme-specific stimulation of phospholipase C-gamma(2) by Rac GTPases. J. Biol. Chem. 280, 38923-38931 CrossRef PubMed
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 38923-38931
-
-
Piechulek, T.1
Rehlen, T.2
Walliser, C.3
Vatter, P.4
Moepps, B.5
Gierschik, P.6
-
89
-
-
67649470550
-
Integrin alpha2beta1 induces phosphorylation-dependent and phosphorylation-independent activation of phospholipase Cgamma2 in platelets: Role of Src kinase and Rac GTPase
-
CrossRef PubMed
-
Guidetti, G.F., Bernardi, B., Consonni, A., Rizzo, P., Gruppi, C., Balduini, C. and Torti, M. (2009) Integrin alpha2beta1 induces phosphorylation-dependent and phosphorylation-independent activation of phospholipase Cgamma2 in platelets: role of Src kinase and Rac GTPase. J. Thromb. Haemost. 7, 1200-1206 CrossRef PubMed
-
(2009)
J. Thromb. Haemost.
, vol.7
, pp. 1200-1206
-
-
Guidetti, G.F.1
Bernardi, B.2
Consonni, A.3
Rizzo, P.4
Gruppi, C.5
Balduini, C.6
Torti, M.7
-
90
-
-
20144389927
-
WAVE/Scars in platelets
-
CrossRef PubMed
-
Oda, A., Miki, H., Wada, I., Yamaguchi, H., Yamazaki, D., Suetsugu, S., Nakajima, M., Nakayama, A., Okawa, K., Miyazaki, H. et al. (2005) WAVE/Scars in platelets. Blood 105, 3141-3148 CrossRef PubMed
-
(2005)
Blood
, vol.105
, pp. 3141-3148
-
-
Oda, A.1
Miki, H.2
Wada, I.3
Yamaguchi, H.4
Yamazaki, D.5
Suetsugu, S.6
Nakajima, M.7
Nakayama, A.8
Okawa, K.9
Miyazaki, H.10
-
91
-
-
0032473498
-
Gelsolin is a downstream effector of rac for fibroblast motility
-
CrossRef PubMed
-
Azuma, T., Witke, W., Stossel, T.T., Hartwig, J.H. and Kwiatkowski, D.J. (1998) Gelsolin is a downstream effector of rac for fibroblast motility. EMBO J. 17, 1362-1370 CrossRef PubMed
-
(1998)
EMBO J.
, vol.17
, pp. 1362-1370
-
-
Azuma, T.1
Witke, W.2
Stossel, T.T.3
Hartwig, J.H.4
Kwiatkowski, D.J.5
-
92
-
-
0034776550
-
The Arp2/3 complex: A central regulator of the actin cytoskeleton
-
CrossRef PubMed
-
May, R.C. (2001) The Arp2/3 complex: a central regulator of the actin cytoskeleton. Cell. Mol. Life Sci. 58, 1607-1626 CrossRef PubMed
-
(2001)
Cell. Mol. Life Sci.
, vol.58
, pp. 1607-1626
-
-
May, R.C.1
-
93
-
-
84888242635
-
Defective tubulin organization and proplatelet formation in murine megakaryocytes lacking Rac1 and Cdc42
-
CrossRef PubMed
-
Pleines, I., Dutting, S., Cherpokova, D., Eckly, A., Meyer, I., Morowski, M., Krohne, G., Schulze, H., Gachet, C., Debili, N. et al. (2013) Defective tubulin organization and proplatelet formation in murine megakaryocytes lacking Rac1 and Cdc42. Blood 122, 3178-3187 CrossRef PubMed
-
(2013)
Blood
, vol.122
, pp. 3178-3187
-
-
Pleines, I.1
Dutting, S.2
Cherpokova, D.3
Eckly, A.4
Meyer, I.5
Morowski, M.6
Krohne, G.7
Schulze, H.8
Gachet, C.9
Debili, N.10
-
94
-
-
0026642504
-
Growth-regulated expression of rhoG, a new member of the ras homolog gene family
-
PubMed
-
Vincent, S., Jeanteur, P. and Fort, P. (1992) Growth-regulated expression of rhoG, a new member of the ras homolog gene family. Mol. Cell. Biol. 12, 3138-3148 PubMed
-
(1992)
Mol. Cell. Biol.
, vol.12
, pp. 3138-3148
-
-
Vincent, S.1
Jeanteur, P.2
Fort, P.3
-
95
-
-
3042801758
-
SGEF, a RhoG guanine nucleotide exchange factor that stimulates macropinocytosis
-
CrossRef PubMed
-
Ellerbroek, S.M., Wennerberg, K., Arthur, W.T., Dunty, J.M., Bowman, D.R., DeMali, K.A., Der, C. and Burridge, K. (2004) SGEF, a RhoG guanine nucleotide exchange factor that stimulates macropinocytosis. Mol. Biol. Cell 15, 3309-3319 CrossRef PubMed
-
(2004)
Mol. Biol. Cell
, vol.15
, pp. 3309-3319
-
-
Ellerbroek, S.M.1
Wennerberg, K.2
Arthur, W.T.3
Dunty, J.M.4
Bowman, D.R.5
DeMali, K.A.6
Der, C.7
Burridge, K.8
-
96
-
-
77955444009
-
Ephexin4 and EphA2 mediate cell migration through a RhoG-dependent mechanism
-
CrossRef PubMed
-
Hiramoto-Yamaki, N., Takeuchi, S., Ueda, S., Harada, K., Fujimoto, S., Negishi, M. and Katoh, H. (2010) Ephexin4 and EphA2 mediate cell migration through a RhoG-dependent mechanism. J. Cell Biol. 190, 461-477 CrossRef PubMed
-
(2010)
J. Cell Biol.
, vol.190
, pp. 461-477
-
-
Hiramoto-Yamaki, N.1
Takeuchi, S.2
Ueda, S.3
Harada, K.4
Fujimoto, S.5
Negishi, M.6
Katoh, H.7
-
97
-
-
0035021049
-
Interactions between Rho GTPases and Rho GDP dissociation inhibitor (Rho-GDI)
-
CrossRef PubMed
-
Faure, J. and Dagher, M.C. (2001) Interactions between Rho GTPases and Rho GDP dissociation inhibitor (Rho-GDI). Biochimie 83, 409-414 CrossRef PubMed
-
(2001)
Biochimie
, vol.83
, pp. 409-414
-
-
Faure, J.1
Dagher, M.C.2
-
98
-
-
0029828539
-
RhoGDI-3 is a new GDP dissociation inhibitor (GDI). Identification of a non-cytosolic GDI protein interacting with the small GTP-binding proteins RhoB and RhoG
-
CrossRef PubMed
-
Zalcman, G., Closson, V., Camonis, J., Honore, N., Rousseau-Merck, M.F., Tavitian, A. and Olofsson, B. (1996) RhoGDI-3 is a new GDP dissociation inhibitor (GDI). Identification of a non-cytosolic GDI protein interacting with the small GTP-binding proteins RhoB and RhoG. J. Biol. Chem. 271, 30366-30374 CrossRef PubMed
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 30366-30374
-
-
Zalcman, G.1
Closson, V.2
Camonis, J.3
Honore, N.4
Rousseau-Merck, M.F.5
Tavitian, A.6
Olofsson, B.7
-
99
-
-
0031815909
-
RhoG GTPase controls a pathway that independently activates Rac1 and Cdc42Hs
-
CrossRef PubMed
-
Gauthier-Rouviere, C., Vignal, E., Meriane, M., Roux, P., Montcourier, P. and Fort, P. (1998) RhoG GTPase controls a pathway that independently activates Rac1 and Cdc42Hs. Mol. Biol. Cell 9, 1379-1394 CrossRef PubMed
-
(1998)
Mol. Biol. Cell
, vol.9
, pp. 1379-1394
-
-
Gauthier-Rouviere, C.1
Vignal, E.2
Meriane, M.3
Roux, P.4
Montcourier, P.5
Fort, P.6
-
100
-
-
0033662155
-
The Rac1- and RhoG-specific GEF domain of Trio targets filamin to remodel cytoskeletal actin
-
CrossRef PubMed
-
Bellanger, J.M., Astier, C., Sardet, C., Ohta, Y., Stossel, T.P. and Debant, A. (2000) The Rac1- and RhoG-specific GEF domain of Trio targets filamin to remodel cytoskeletal actin. Nat. Cell Biol. 2, 888-892 CrossRef PubMed
-
(2000)
Nat. Cell Biol.
, vol.2
, pp. 888-892
-
-
Bellanger, J.M.1
Astier, C.2
Sardet, C.3
Ohta, Y.4
Stossel, T.P.5
Debant, A.6
-
101
-
-
0033835027
-
Small GTPase RhoG is a key regulator for neurite outgrowth in PC12 cells
-
CrossRef PubMed
-
Katoh, H., Yasui, H., Yamaguchi, Y., Aoki, J., Fujita, H., Mori, K. and Negishi, M. (2000) Small GTPase RhoG is a key regulator for neurite outgrowth in PC12 cells. Mol. Cell. Biol. 20, 7378-7387 CrossRef PubMed
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 7378-7387
-
-
Katoh, H.1
Yasui, H.2
Yamaguchi, Y.3
Aoki, J.4
Fujita, H.5
Mori, K.6
Negishi, M.7
-
102
-
-
0037133037
-
The human Rho-GEF trio and its target GTPase RhoG are involved in the NGF pathway, leading to neurite outgrowth
-
CrossRef PubMed
-
Estrach, S., Schmidt, S., Diriong, S., Penna, A., Blangy, A., Fort, P. and Debant, A. (2002) The human Rho-GEF trio and its target GTPase RhoG are involved in the NGF pathway, leading to neurite outgrowth. Curr. Biol. 12, 307-312 CrossRef PubMed
-
(2002)
Curr. Biol.
, vol.12
, pp. 307-312
-
-
Estrach, S.1
Schmidt, S.2
Diriong, S.3
Penna, A.4
Blangy, A.5
Fort, P.6
Debant, A.7
-
103
-
-
0037461959
-
RhoG regulates gene expression and the actin cytoskeleton in lymphocytes
-
CrossRef PubMed
-
Vigorito, E., Billadeu, D.D., Savoy, D., McAdam, S., Doody, G., Fort, P. and Turner, M. (2003) RhoG regulates gene expression and the actin cytoskeleton in lymphocytes. Oncogene 22, 330-342 CrossRef PubMed
-
(2003)
Oncogene
, vol.22
, pp. 330-342
-
-
Vigorito, E.1
Billadeu, D.D.2
Savoy, D.3
McAdam, S.4
Doody, G.5
Fort, P.6
Turner, M.7
-
104
-
-
80054804098
-
The RhoG/ELMO1/Dock180 signaling module is required for spine morphogenesis in hippocampal neurons
-
CrossRef PubMed
-
Kim, J.Y., Oh, M.H., Bernard, L.P., Macara, I.G. and Zhang, H. (2011) The RhoG/ELMO1/Dock180 signaling module is required for spine morphogenesis in hippocampal neurons. J. Biol. Chem. 286, 37615-37624 CrossRef PubMed
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 37615-37624
-
-
Kim, J.Y.1
Oh, M.H.2
Bernard, L.P.3
Macara, I.G.4
Zhang, H.5
-
105
-
-
84856421344
-
Epidermal growth factor induction of front-rear polarity and migration in keratinocytes is mediated by integrin-linked kinase and ELMO2
-
CrossRef PubMed
-
Ho, E. and Dagnino, L. (2012) Epidermal growth factor induction of front-rear polarity and migration in keratinocytes is mediated by integrin-linked kinase and ELMO2. Mol. Biol. Cell 23, 492-502 CrossRef PubMed
-
(2012)
Mol. Biol. Cell
, vol.23
, pp. 492-502
-
-
Ho, E.1
Dagnino, L.2
-
106
-
-
0037033069
-
RhoG signals in parallel with Rac1 and Cdc42
-
CrossRef PubMed
-
Wennerberg, K., Ellerbroek, S.M., Liu, R.Y., Karnoub, A.E., Burridge, K. and Der, C.J. (2002) RhoG signals in parallel with Rac1 and Cdc42. J. Biol. Chem. 277, 47810-47817 CrossRef PubMed
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 47810-47817
-
-
Wennerberg, K.1
Ellerbroek, S.M.2
Liu, R.Y.3
Karnoub, A.E.4
Burridge, K.5
Der, C.J.6
-
107
-
-
0034053503
-
TrioGEF1 controls Rac- and Cdc42-dependent cell structures through the direct activation of rhoG
-
PubMed
-
Blangy, A., Vignal, E., Schmidt, S., Debant, A., Gauthier-Rouviere, C. and Fort, P. (2000) TrioGEF1 controls Rac- and Cdc42-dependent cell structures through the direct activation of rhoG. J. Cell Sci. 113, 729-739 PubMed
-
(2000)
J. Cell Sci.
, vol.113
, pp. 729-739
-
-
Blangy, A.1
Vignal, E.2
Schmidt, S.3
Debant, A.4
Gauthier-Rouviere, C.5
Fort, P.6
-
108
-
-
0042674398
-
RhoG activates Rac1 by direct interaction with the Dock180-binding protein Elmo
-
CrossRef PubMed
-
Katoh, H. and Negishi, M. (2003) RhoG activates Rac1 by direct interaction with the Dock180-binding protein Elmo. Nature 424, 461-464 CrossRef PubMed
-
(2003)
Nature
, vol.424
, pp. 461-464
-
-
Katoh, H.1
Negishi, M.2
-
109
-
-
34447565145
-
Dock4 is regulated by RhoG and promotes Rac-dependent cell migration
-
CrossRef PubMed
-
Hiramoto, K., Negishi, M. and Katoh, H. (2006) Dock4 is regulated by RhoG and promotes Rac-dependent cell migration. Exp. Cell Res. 312, 4205-4216 CrossRef PubMed
-
(2006)
Exp. Cell Res.
, vol.312
, pp. 4205-4216
-
-
Hiramoto, K.1
Negishi, M.2
Katoh, H.3
-
110
-
-
31644445194
-
Activation of Rac1 by RhoG regulates cell migration
-
CrossRef PubMed
-
Katoh, H., Hiramoto, K. and Negishi, M. (2006) Activation of Rac1 by RhoG regulates cell migration. J. Cell Sci. 119, 56-65 CrossRef PubMed
-
(2006)
J. Cell Sci.
, vol.119
, pp. 56-65
-
-
Katoh, H.1
Hiramoto, K.2
Negishi, M.3
-
111
-
-
0346095321
-
Immunological Function in Mice Lacking the Rac-Related GTPase RhoG
-
CrossRef PubMed
-
Vigorito, E., Bell, S., Hebeis, B.J., Reynolds, H., McAdam, S., Emson, P.C., McKenzie, A. and Turner, M. (2004) Immunological Function in Mice Lacking the Rac-Related GTPase RhoG. Mol. Cell. Biol. 24, 719-729 CrossRef PubMed
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 719-729
-
-
Vigorito, E.1
Bell, S.2
Hebeis, B.J.3
Reynolds, H.4
McAdam, S.5
Emson, P.C.6
McKenzie, A.7
Turner, M.8
-
112
-
-
84888386815
-
RhoG protein regulates platelet granule secretion and thrombus formation in mice
-
CrossRef PubMed
-
Goggs, R., Harper, M.T., Pope, R.J., Savage, J.S., Williams, C.M., Mundell, S.J., Heesom, K.J., Bass, M., Mellor, H. and Poole, A.W. (2013) RhoG protein regulates platelet granule secretion and thrombus formation in mice. J. Biol. Chem. 288, 34217-34229 CrossRef PubMed
-
(2013)
J. Biol. Chem.
, vol.288
, pp. 34217-34229
-
-
Goggs, R.1
Harper, M.T.2
Pope, R.J.3
Savage, J.S.4
Williams, C.M.5
Mundell, S.J.6
Heesom, K.J.7
Bass, M.8
Mellor, H.9
Poole, A.W.10
-
113
-
-
0034213327
-
Rho GTPases and their effector proteins
-
CrossRef PubMed
-
Bishop, A.L. and Hall, A. (2000) Rho GTPases and their effector proteins. Biochem. J. 348, 241-255 CrossRef PubMed
-
(2000)
Biochem. J.
, vol.348
, pp. 241-255
-
-
Bishop, A.L.1
Hall, A.2
-
114
-
-
81855166736
-
Analysis of protein networks in resting and collagen receptor (GPVI)-stimulated platelet sub-proteomes
-
CrossRef PubMed
-
Wright, B., Stanley, R.G., Kaiser, W.J., Mills, D.J. and Gibbins, J.M. (2011) Analysis of protein networks in resting and collagen receptor (GPVI)-stimulated platelet sub-proteomes. Proteomics 11, 4588-4592 CrossRef PubMed
-
(2011)
Proteomics
, vol.11
, pp. 4588-4592
-
-
Wright, B.1
Stanley, R.G.2
Kaiser, W.J.3
Mills, D.J.4
Gibbins, J.M.5
-
115
-
-
84888337769
-
RhoG protein regulates glycoprotein VI-Fc receptor gamma-chain complex-mediated platelet activation and thrombus formation
-
CrossRef PubMed
-
Kim, S., Dangelmaier, C., Bhavanasi, D., Meng, S., Wang, H., Goldfinger, L.E. and Kunapuli, S.P. (2013) RhoG protein regulates glycoprotein VI-Fc receptor gamma-chain complex-mediated platelet activation and thrombus formation. J. Biol. Chem. 288, 34230-34238 CrossRef PubMed
-
(2013)
J. Biol. Chem.
, vol.288
, pp. 34230-34238
-
-
Kim, S.1
Dangelmaier, C.2
Bhavanasi, D.3
Meng, S.4
Wang, H.5
Goldfinger, L.E.6
Kunapuli, S.P.7
-
116
-
-
33744455164
-
Thrombin overcomes the thrombosis defect associated with platelet GPVI/FcRgamma deficiency
-
CrossRef PubMed
-
Mangin, P., Yap, C.L., Nonne, C., Sturgeon, S.A., Goncalves, I., Yuan, Y., Schoenwaelder, S.M., Wright, C.E., Lanza, F. and Jackson, S.P. (2006) Thrombin overcomes the thrombosis defect associated with platelet GPVI/FcRgamma deficiency. Blood 107, 4346-4353 CrossRef PubMed
-
(2006)
Blood
, vol.107
, pp. 4346-4353
-
-
Mangin, P.1
Yap, C.L.2
Nonne, C.3
Sturgeon, S.A.4
Goncalves, I.5
Yuan, Y.6
Schoenwaelder, S.M.7
Wright, C.E.8
Lanza, F.9
Jackson, S.P.10
-
117
-
-
78751701028
-
Rho GTPases and exocytosis: What are the molecular links?
-
CrossRef PubMed
-
Ory, S. and Gasman, S. (2011) Rho GTPases and exocytosis: what are the molecular links? Semin. Cell Dev. Biol. 22, 27-32 CrossRef PubMed
-
(2011)
Semin. Cell Dev. Biol.
, vol.22
, pp. 27-32
-
-
Ory, S.1
Gasman, S.2
-
118
-
-
77952823490
-
The platelet actin cytoskeleton associates with SNAREs and participates in alpha-granule secretion
-
CrossRef PubMed
-
Woronowicz, K., Dilks, J.R., Rozenvayn, N., Dowal, L., Blair, P.S., Peters, C.G., Woronowicz, L. and Flaumenhaft, R. (2010) The platelet actin cytoskeleton associates with SNAREs and participates in alpha-granule secretion. Biochemistry 49, 4533-4542 CrossRef PubMed
-
(2010)
Biochemistry
, vol.49
, pp. 4533-4542
-
-
Woronowicz, K.1
Dilks, J.R.2
Rozenvayn, N.3
Dowal, L.4
Blair, P.S.5
Peters, C.G.6
Woronowicz, L.7
Flaumenhaft, R.8
-
119
-
-
0037199471
-
A link between Cdc42 and syntaxin is involved in mastoparan-stimulated insulin release
-
CrossRef PubMed
-
Daniel, S., Noda, M., Cerione, R.A. and Sharp, G.W. (2002) A link between Cdc42 and syntaxin is involved in mastoparan-stimulated insulin release. Biochemistry 41, 9663-9671 CrossRef PubMed
-
(2002)
Biochemistry
, vol.41
, pp. 9663-9671
-
-
Daniel, S.1
Noda, M.2
Cerione, R.A.3
Sharp, G.W.4
-
120
-
-
0032538792
-
Phosphorylation-dependent and constitutive activation of Rho proteins by wild-type and oncogenic Vav-2
-
CrossRef PubMed'
-
Schuebel, K.E., Movilla, N., Rosa, J.L. and Bustelo, X.R. (1998) Phosphorylation-dependent and constitutive activation of Rho proteins by wild-type and oncogenic Vav-2. EMBO J. 17, 6608-6621 CrossRef PubMed'
-
(1998)
EMBO J.
, vol.17
, pp. 6608-6621
-
-
Schuebel, K.E.1
Movilla, N.2
Rosa, J.L.3
Bustelo, X.R.4
-
121
-
-
0037111633
-
Vav1, but not Vav2, contributes to platelet aggregation by CRP and thrombin, but neither is required for regulation of phospholipase C
-
CrossRef PubMed
-
Pearce, A.C., Wilde, J.I., Doody, G.M., Best, D., Inoue, O., Vigorito, E., Tybulewicz, V.L., Turner, M. and Watson, S.P. (2002) Vav1, but not Vav2, contributes to platelet aggregation by CRP and thrombin, but neither is required for regulation of phospholipase C. Blood 100, 3561-3569 CrossRef PubMed
-
(2002)
Blood
, vol.100
, pp. 3561-3569
-
-
Pearce, A.C.1
Wilde, J.I.2
Doody, G.M.3
Best, D.4
Inoue, O.5
Vigorito, E.6
Tybulewicz, V.L.7
Turner, M.8
Watson, S.P.9
-
122
-
-
84855468015
-
The N-terminal DH-PH domain of Trio induces cell spreading and migration by regulating lamellipodia dynamics in a Rac1-dependent fashion
-
CrossRef PubMed
-
van Rijssel, J., Hoogenboezem, M., Wester, L., Hordijk, P.L. and Van Buul, J.D. (2012) The N-terminal DH-PH domain of Trio induces cell spreading and migration by regulating lamellipodia dynamics in a Rac1-dependent fashion. PLoS One 7, e29912 CrossRef PubMed
-
(2012)
PLoS One
, vol.7
-
-
Van Rijssel, J.1
Hoogenboezem, M.2
Wester, L.3
Hordijk, P.L.4
Van Buul, J.D.5
-
123
-
-
84873866382
-
Tyrosine phosphorylation of the Rho guanine nucleotide exchange factor Trio regulates netrin-1/DCC-mediated cortical axon outgrowth
-
CrossRef PubMed
-
DeGeer, J., Boudeau, J., Schmidt, S., Bedford, F., Lamarche-Vane, N. and Debant, A. (2013) Tyrosine phosphorylation of the Rho guanine nucleotide exchange factor Trio regulates netrin-1/DCC-mediated cortical axon outgrowth. Mol. Cell. Biol. 33, 739-751 CrossRef PubMed
-
(2013)
Mol. Cell. Biol.
, vol.33
, pp. 739-751
-
-
DeGeer, J.1
Boudeau, J.2
Schmidt, S.3
Bedford, F.4
Lamarche-Vane, N.5
Debant, A.6
-
124
-
-
33645240619
-
Secramine inhibits Cdc42-dependent functions in cells and Cdc42 activation in vitro
-
CrossRef PubMed
-
Pelish, H.E., Peterson, J.R., Salvarezza, S.B., Rodriguez-Boulan, E., Chen, J.L., Stamnes, M., Macia, E., Feng, Y., Shair, M.D. and Kirchhausen, T. (2006) Secramine inhibits Cdc42-dependent functions in cells and Cdc42 activation in vitro. Nat. Chem. Biol. 2, 39-46 CrossRef PubMed
-
(2006)
Nat. Chem. Biol.
, vol.2
, pp. 39-46
-
-
Pelish, H.E.1
Peterson, J.R.2
Salvarezza, S.B.3
Rodriguez-Boulan, E.4
Chen, J.L.5
Stamnes, M.6
Macia, E.7
Feng, Y.8
Shair, M.D.9
Kirchhausen, T.10
-
125
-
-
33845512493
-
PKCdelta regulates collagen-induced platelet aggregation through inhibition of VASP-mediated filopodia formation
-
CrossRef PubMed
-
Pula, G., Schuh, K., Nakayama, K., Nakayama, K.I., Walter, U. and Poole, A.W. (2006) PKCdelta regulates collagen-induced platelet aggregation through inhibition of VASP-mediated filopodia formation. Blood 108, 4035-4044 CrossRef PubMed
-
(2006)
Blood
, vol.108
, pp. 4035-4044
-
-
Pula, G.1
Schuh, K.2
Nakayama, K.3
Nakayama, K.I.4
Walter, U.5
Poole, A.W.6
-
126
-
-
0037097589
-
Arp2/3 complex is required for actin polymerization during platelet shape change
-
CrossRef PubMed
-
Li, Z., Kim, E.S. and Bearer, E.L. (2002) Arp2/3 complex is required for actin polymerization during platelet shape change. Blood 99, 4466-4474 CrossRef PubMed
-
(2002)
Blood
, vol.99
, pp. 4466-4474
-
-
Li, Z.1
Kim, E.S.2
Bearer, E.L.3
-
127
-
-
33746947884
-
Sleeping beauty transposon-based phenotypic analysis of mice: Lack of Arpc3 results in defective trophoblast outgrowth
-
CrossRef PubMed
-
Yae, K., Keng, V.W., Koike, M., Yusa, K., Kouno, M., Uno, Y., Kondoh, G., Gotow, T., Uchiyama, Y., Horie, K. and Takeda, J. (2006) Sleeping beauty transposon-based phenotypic analysis of mice: lack of Arpc3 results in defective trophoblast outgrowth. Mol. Cell. Biol. 26, 6185-6196 CrossRef PubMed
-
(2006)
Mol. Cell. Biol.
, vol.26
, pp. 6185-6196
-
-
Yae, K.1
Keng, V.W.2
Koike, M.3
Yusa, K.4
Kouno, M.5
Uno, Y.6
Kondoh, G.7
Gotow, T.8
Uchiyama, Y.9
Horie, K.10
Takeda, J.11
-
128
-
-
10044275155
-
Integration of signalling pathways regulated by small GTPases and calcium
-
Aspenstrom, P. (2004) Integration of signalling pathways regulated by small GTPases and calcium. Biochim. Biophys. Acta 1742, 51-58
-
(2004)
Biochim. Biophys. Acta
, vol.1742
, pp. 51-58
-
-
Aspenstrom, P.1
-
129
-
-
84874433733
-
Regulation of small GTPases by GEFs, GAPs, and GDIs
-
CrossRef PubMed
-
Cherfils, J. and Zeghouf, M. (2013) Regulation of small GTPases by GEFs, GAPs, and GDIs. Physiol. Rev. 93, 269-309 CrossRef PubMed
-
(2013)
Physiol. Rev.
, vol.93
, pp. 269-309
-
-
Cherfils, J.1
Zeghouf, M.2
-
130
-
-
0037155727
-
P-Rex1, a PtdIns(3,4,5)P3- and Gbetagamma-regulated guanine-nucleotide exchange factor for Rac
-
CrossRef PubMed
-
Welch, H.C., Coadwell, W.J., Ellson, C.D., Ferguson, G.J., Andrews, S.R., Erdjument-Bromage, H., Tempst, P., Hawkins, P.T. and Stephens, L.R. (2002) P-Rex1, a PtdIns(3,4,5)P3- and Gbetagamma-regulated guanine-nucleotide exchange factor for Rac. Cell 108, 809-821 CrossRef PubMed
-
(2002)
Cell
, vol.108
, pp. 809-821
-
-
Welch, H.C.1
Coadwell, W.J.2
Ellson, C.D.3
Ferguson, G.J.4
Andrews, S.R.5
Erdjument-Bromage, H.6
Tempst, P.7
Hawkins, P.T.8
Stephens, L.R.9
-
131
-
-
26444535506
-
GPVI and integrin alphaIIb beta3 signaling in platelets
-
CrossRef PubMed
-
Watson, S.P., Auger, J.M., McCarty, O.J. and Pearce, A.C. (2005) GPVI and integrin alphaIIb beta3 signaling in platelets. J. Thromb. Haemost. 3, 1752-1762 CrossRef PubMed
-
(2005)
J. Thromb. Haemost.
, vol.3
, pp. 1752-1762
-
-
Watson, S.P.1
Auger, J.M.2
McCarty, O.J.3
Pearce, A.C.4
-
132
-
-
67649566345
-
A cell active chemical GEF inhibitor selectively targets the Trio/RhoG/Rac1 signaling pathway
-
CrossRef PubMed
-
Bouquier, N., Vignal, E., Charrasse, S., Weill, M., Schmidt, S., Leonetti, J.P., Blangy, A. and Fort, P. (2009) A cell active chemical GEF inhibitor selectively targets the Trio/RhoG/Rac1 signaling pathway. Chem. Biol. 16, 657-666 CrossRef PubMed
-
(2009)
Chem. Biol.
, vol.16
, pp. 657-666
-
-
Bouquier, N.1
Vignal, E.2
Charrasse, S.3
Weill, M.4
Schmidt, S.5
Leonetti, J.P.6
Blangy, A.7
Fort, P.8
-
133
-
-
77955296002
-
Trio is a key guanine nucleotide exchange factor coordinating regulation of the migration and morphogenesis of granule cells in the developing cerebellum
-
CrossRef PubMed
-
Peng, Y.J., He, W.Q., Tang, J., Tao, T., Chen, C., Gao, Y.Q., Zhang, W.C., He, X.Y., Dai, Y.Y., Zhu, N.C. et al. (2010) Trio is a key guanine nucleotide exchange factor coordinating regulation of the migration and morphogenesis of granule cells in the developing cerebellum. J. Biol. Chem. 285, 24834-24844 CrossRef PubMed
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 24834-24844
-
-
Peng, Y.J.1
He, W.Q.2
Tang, J.3
Tao, T.4
Chen, C.5
Gao, Y.Q.6
Zhang, W.C.7
He, X.Y.8
Dai, Y.Y.9
Zhu, N.C.10
-
134
-
-
77951719965
-
Endogenous RhoG is rapidly activated after epidermal growth factor stimulation through multiple guanine-nucleotide exchange factors
-
CrossRef PubMed
-
Samson, T., Welch, C., Monaghan-Benson, E., Hahn, K.M. and Burridge, K. (2010) Endogenous RhoG is rapidly activated after epidermal growth factor stimulation through multiple guanine-nucleotide exchange factors. Mol. Biol. Cell 21, 1629-1642 CrossRef PubMed
-
(2010)
Mol. Biol. Cell
, vol.21
, pp. 1629-1642
-
-
Samson, T.1
Welch, C.2
Monaghan-Benson, E.3
Hahn, K.M.4
Burridge, K.5
-
135
-
-
84878648237
-
RhoGEF12 controls cardiac remodeling by integrating G protein- and integrin-dependent signaling cascades
-
CrossRef PubMed
-
Takefuji, M., Kruger, M., Sivaraj, K.K., Kaibuchi, K., Offermanns, S. and Wettschureck, N. (2013) RhoGEF12 controls cardiac remodeling by integrating G protein- and integrin-dependent signaling cascades. J. Exp. Med. 210, 665-673 CrossRef PubMed
-
(2013)
J. Exp. Med.
, vol.210
, pp. 665-673
-
-
Takefuji, M.1
Kruger, M.2
Sivaraj, K.K.3
Kaibuchi, K.4
Offermanns, S.5
Wettschureck, N.6
-
136
-
-
0028122478
-
RAS-15A protein shares highly similar dominant-negative biological properties with RAS-17N and forms a stable, guanine-nucleotide resistant complex with CDC25 exchange factor
-
PubMed
-
Chen, S.Y., Huff, S.Y., Lai, C.C., Der, C.J. and Powers, S. (1994) RAS-15A protein shares highly similar dominant-negative biological properties with RAS-17N and forms a stable, guanine-nucleotide resistant complex with CDC25 exchange factor. Oncogene 9, 2691-2698 PubMed
-
(1994)
Oncogene
, vol.9
, pp. 2691-2698
-
-
Chen, S.Y.1
Huff, S.Y.2
Lai, C.C.3
Der, C.J.4
Powers, S.5
-
137
-
-
0033179296
-
GEFs: Structural basis for their activation of small GTP-binding proteins
-
CrossRef PubMed
-
Cherfils, J. and Chardin, P. (1999) GEFs: structural basis for their activation of small GTP-binding proteins. Trends Biochem. Sci. 24, 306-311 CrossRef PubMed
-
(1999)
Trends Biochem. Sci.
, vol.24
, pp. 306-311
-
-
Cherfils, J.1
Chardin, P.2
-
138
-
-
32144453465
-
Analysis of activated GAPs and GEFs in cell lysates
-
William, E., Balch, C. J. D. and Alan, H., eds Academic Press CrossRef
-
García-Mata, R., Wennerberg, K., Arthur, W.T., Noren, N.K., Ellerbroek, S.M. and Burridge, K. (2006) Analysis of activated GAPs and GEFs in cell lysates. In Methods in Enzymology (William, E., Balch, C. J. D. and Alan, H., eds), pp. 425-437, Academic Press CrossRef
-
(2006)
Methods in Enzymology
, pp. 425-437
-
-
García-Mata, R.1
Wennerberg, K.2
Arthur, W.T.3
Noren, N.K.4
Ellerbroek, S.M.5
Burridge, K.6
-
139
-
-
33846969965
-
Current knowledge of the large RhoGAP family of proteins
-
CrossRef PubMed
-
Tcherkezian, J. and Lamarche-Vane, N. (2007) Current knowledge of the large RhoGAP family of proteins. Biol. Cell 99, 67-86 CrossRef PubMed
-
(2007)
Biol. Cell
, vol.99
, pp. 67-86
-
-
Tcherkezian, J.1
Lamarche-Vane, N.2
-
140
-
-
84867599719
-
Isoform-specific roles of the GTPase activating protein Nadrin in cytoskeletal reorganization of platelets
-
CrossRef PubMed
-
Beck, S., Fotinos, A., Lang, F., Gawaz, M. and Elvers, M. (2013) Isoform-specific roles of the GTPase activating protein Nadrin in cytoskeletal reorganization of platelets. Cell Signal. 25, 236-246 CrossRef PubMed
-
(2013)
Cell Signal.
, vol.25
, pp. 236-246
-
-
Beck, S.1
Fotinos, A.2
Lang, F.3
Gawaz, M.4
Elvers, M.5
-
141
-
-
84861404332
-
The GRAF family member oligophrenin1 is a RhoGAP with BAR domain and regulates Rho GTPases in platelets
-
CrossRef PubMed
-
Elvers, M., Beck, S., Fotinos, A., Ziegler, M. and Gawaz, M. (2012) The GRAF family member oligophrenin1 is a RhoGAP with BAR domain and regulates Rho GTPases in platelets. Cardiovasc. Res. 94, 526-536 CrossRef PubMed
-
(2012)
Cardiovasc. Res.
, vol.94
, pp. 526-536
-
-
Elvers, M.1
Beck, S.2
Fotinos, A.3
Ziegler, M.4
Gawaz, M.5
-
142
-
-
84879119973
-
Targeted phosphotyrosine profiling of glycoprotein VI signaling implicates oligophrenin-1 in platelet filopodia formation
-
CrossRef PubMed
-
Bleijerveld, O.B., van Holten, T.C., Preisinger, C., van der Smagt, J.J., Farndale, R.W., Kleefstra, T., Willemsen, M.H., Urbanus, R.T., de Groot, P.G., Heck, A.J. et al. (2013) Targeted phosphotyrosine profiling of glycoprotein VI signaling implicates oligophrenin-1 in platelet filopodia formation. Arterioscler. Thromb. Vasc. Biol. 33, 1538-1543 CrossRef PubMed
-
(2013)
Arterioscler. Thromb. Vasc. Biol.
, vol.33
, pp. 1538-1543
-
-
Bleijerveld, O.B.1
Van Holten, T.C.2
Preisinger, C.3
Van Der Smagt, J.J.4
Farndale, R.W.5
Kleefstra, T.6
Willemsen, M.H.7
Urbanus, R.T.8
De Groot, P.G.9
Heck, A.J.10
-
143
-
-
84872832748
-
The guanine-nucleotide exchange factor SGEF plays a crucial role in the formation of atherosclerosis
-
CrossRef PubMed
-
Samson, T., van Buul, J.D., Kroon, J., Welch, C., Bakker, E.N., Matlung, H.L., van den Berg, T.K., Sharek, L., Doerschuk, C., Hahn, K. and Burridge, K. (2013) The guanine-nucleotide exchange factor SGEF plays a crucial role in the formation of atherosclerosis. PLoS One 8, e55202 CrossRef PubMed
-
(2013)
PLoS One
, vol.8
-
-
Samson, T.1
Van Buul, J.D.2
Kroon, J.3
Welch, C.4
Bakker, E.N.5
Matlung, H.L.6
Van Den Berg, T.K.7
Sharek, L.8
Doerschuk, C.9
Hahn, K.10
Burridge, K.11
-
144
-
-
34247175312
-
GTP-binding proteins of the Rho/Rac family: Regulation, effectors and functions in vivo
-
CrossRef PubMed
-
Bustelo, X.R., Sauzeau, V. and Berenjeno, I.M. (2007) GTP-binding proteins of the Rho/Rac family: regulation, effectors and functions in vivo. Bioessays. 29, 356-370 CrossRef PubMed
-
(2007)
Bioessays.
, vol.29
, pp. 356-370
-
-
Bustelo, X.R.1
Sauzeau, V.2
Berenjeno, I.M.3
-
145
-
-
84901599553
-
A draft map of the human proteome
-
CrossRef PubMed
-
Kim, M.S., Pinto, S.M., Getnet, D., Nirujogi, R.S., Manda, S.S., Chaerkady, R., Madugundu, A.K., Kelkar, D.S., Isserlin, R., Jain, S. et al. (2014) A draft map of the human proteome. Nature 509, 575-581 CrossRef PubMed
-
(2014)
Nature
, vol.509
, pp. 575-581
-
-
Kim, M.S.1
Pinto, S.M.2
Getnet, D.3
Nirujogi, R.S.4
Manda, S.S.5
Chaerkady, R.6
Madugundu, A.K.7
Kelkar, D.S.8
Isserlin, R.9
Jain, S.10
-
146
-
-
84901611036
-
Mass-spectrometry-based draft of the human proteome
-
CrossRef PubMed
-
Wilhelm, M., Schlegl, J., Hahne, H., Moghaddas Gholami, A., Lieberenz, M., Savitski, M.M., Ziegler, E., Butzmann, L., Gessulat, S., Marx, H. et al. (2014) Mass-spectrometry-based draft of the human proteome. Nature 509, 582-587 CrossRef PubMed
-
(2014)
Nature
, vol.509
, pp. 582-587
-
-
Wilhelm, M.1
Schlegl, J.2
Hahne, H.3
Moghaddas Gholami, A.4
Lieberenz, M.5
Savitski, M.M.6
Ziegler, E.7
Butzmann, L.8
Gessulat, S.9
Marx, H.10
-
147
-
-
0035135929
-
Small GTP-binding proteins
-
PubMed
-
Takai, Y., Sasaki, T. and Matozaki, T. (2001) Small GTP-binding proteins. Physiol. Rev. 81, 153-208 PubMed
-
(2001)
Physiol. Rev.
, vol.81
, pp. 153-208
-
-
Takai, Y.1
Sasaki, T.2
Matozaki, T.3
|