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Volumn 288, Issue 47, 2013, Pages 34230-34238

RhoG protein regulates glycoprotein VI-Fc receptor γ-chain complex-mediated platelet activation and thrombus formation

Author keywords

[No Author keywords available]

Indexed keywords

DENSE GRANULES; INTEGRINS; PLATELET ACTIVATION; PLATELET AGGREGATION; SIGNALING MOLECULES; SRC-FAMILY KINASE; THROMBUS FORMATION; WILD TYPES;

EID: 84888337769     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.504928     Document Type: Article
Times cited : (21)

References (51)
  • 2
    • 0032102098 scopus 로고    scopus 로고
    • Collagen receptor signalling in platelets: Extending the role of the ITAM
    • Watson, S. P., and Gibbins, J. (1998) Collagen receptor signalling in platelets: extending the role of the ITAM. Immunol Today 19, 260-264
    • (1998) Immunol Today , vol.19 , pp. 260-264
    • Watson, S.P.1    Gibbins, J.2
  • 3
    • 0030790042 scopus 로고    scopus 로고
    • Glycoprotein VI is the collagen receptor in platelets which underlies tyrosine phosphorylation of the Fc receptor γ-chain
    • Gibbins, J. M., Okuma, M., Farndale, R., Barnes, M., and Watson, S. P. (1997) Glycoprotein VI is the collagen receptor in platelets which underlies tyrosine phosphorylation of the Fc receptor γ-chain. FEBS Lett. 413, 255-259
    • (1997) FEBS Lett. , vol.413 , pp. 255-259
    • Gibbins, J.M.1    Okuma, M.2    Farndale, R.3    Barnes, M.4    Watson, S.P.5
  • 4
    • 0034604575 scopus 로고    scopus 로고
    • Expression and function of the mouse collagen receptor glycoprotein VI is strictly dependent on its association with the FcRγ chain
    • Nieswandt, B., Bergmeier, W., Schulte, V., Rackebrandt, K., Gessner, J. E., and Zirngibl, H. (2000) Expression and function of the mouse collagen receptor glycoprotein VI is strictly dependent on its association with the FcRγ chain. J. Biol. Chem. 275, 23998-24002
    • (2000) J. Biol. Chem. , vol.275 , pp. 23998-24002
    • Nieswandt, B.1    Bergmeier, W.2    Schulte, V.3    Rackebrandt, K.4    Gessner, J.E.5    Zirngibl, H.6
  • 5
    • 0031825550 scopus 로고    scopus 로고
    • Physical and functional association of the Src family kinases Fyn and Lyn with the collagen receptor glycoprotein VI-Fc receptor γ chain complex on human platelets
    • Ezumi, Y., Shindoh, K., Tsuji, M., and Takayama, H. (1998) Physical and functional association of the Src family kinases Fyn and Lyn with the collagen receptor glycoprotein VI-Fc receptor γ chain complex on human platelets. J. Exp. Med. 188, 267-276
    • (1998) J. Exp. Med. , vol.188 , pp. 267-276
    • Ezumi, Y.1    Shindoh, K.2    Tsuji, M.3    Takayama, H.4
  • 6
    • 0031023917 scopus 로고    scopus 로고
    • Collagen-stimulated activation of Syk but not c-Src is severely compromised in human platelets lacking membrane glycoprotein VI
    • Ichinohe, T., Takayama, H., Ezumi, Y., Arai, M., Yamamoto, N, Takahashi, H., and Okuma, M. (1997) Collagen-stimulated activation of Syk but not c-Src is severely compromised in human platelets lacking membrane glycoprotein VI. J. Biol. Chem. 272, 63-68
    • (1997) J. Biol. Chem. , vol.272 , pp. 63-68
    • Ichinohe, T.1    Takayama, H.2    Ezumi, Y.3    Arai, M.4    Yamamoto, N.5    Takahashi, H.6    Okuma, M.7
  • 7
  • 8
    • 0034672357 scopus 로고    scopus 로고
    • Fyn and Lyn phosphorylate the Fc receptor γ chain downstream of glycoprotein VI in murine platelets, and Lyn regulates a novel feedback pathway
    • Quek, L. S., Pasquet, J. M., Hers, I., Cornall, R., Knight, G., Barnes, M., Hibbs, M. L., Dunn, A. R., Lowell, C. A., and Watson, S. P. (2000) Fyn and Lyn phosphorylate the Fc receptor γ chain downstream of glycoprotein VI in murine platelets, and Lyn regulates a novel feedback pathway. Blood 96, 4246-4253
    • (2000) Blood , vol.96 , pp. 4246-4253
    • Quek, L.S.1    Pasquet, J.M.2    Hers, I.3    Cornall, R.4    Knight, G.5    Barnes, M.6    Hibbs, M.L.7    Dunn, A.R.8    Lowell, C.A.9    Watson, S.P.10
  • 10
    • 0032545307 scopus 로고    scopus 로고
    • Thep85 subunitofphosphatidylinositol 3-kinase associates with the Fc receptor γ-chain and linker for activitor of T cells (LAT) in platelets stimulated by collagen and convulxin
    • Gibbins, J. M., Briddon, S., Shutes, A., van Vugt, M. J., van de Winkel, J. G., Saito, T., and Watson, S. P. (1998) Thep85 subunitofphosphatidylinositol 3-kinase associates with the Fc receptor γ-chain and linker for activitor of T cells (LAT) in platelets stimulated by collagen and convulxin. J. Biol. Chem. 273, 34437-34443
    • (1998) J. Biol. Chem. , vol.273 , pp. 34437-34443
    • Gibbins, J.M.1    Briddon, S.2    Shutes, A.3    Van Vugt, M.J.4    Van De Winkel, J.G.5    Saito, T.6    Watson, S.P.7
  • 11
    • 0033033956 scopus 로고    scopus 로고
    • Phosphatidylinositol 3'-kinase and tyrosine-phosphatase activation positively modulate convulxin-induced platelet activation. Comparison with collagen
    • Lagrue, A. H., Francischetti, I. M., Guimarães, J. A., and Jandrot-Perrus, M. (1999) Phosphatidylinositol 3'-kinase and tyrosine-phosphatase activation positively modulate convulxin-induced platelet activation. Comparison with collagen. FEBS Lett. 448, 95-100
    • (1999) FEBS Lett. , vol.448 , pp. 95-100
    • Lagrue, A.H.1    Francischetti, I.M.2    Guimarães, J.A.3    Jandrot-Perrus, M.4
  • 12
    • 0032497629 scopus 로고    scopus 로고
    • A role for Bruton's tyrosine kinase (Btk) in platelet activation by collagen
    • Quek, L. S., Bolen, J., and Watson, S. P. (1998) A role for Bruton's tyrosine kinase (Btk) in platelet activation by collagen. Curr. Biol. 8, 1137-1140
    • (1998) Curr. Biol. , vol.8 , pp. 1137-1140
    • Quek, L.S.1    Bolen, J.2    Watson, S.P.3
  • 13
    • 0028043160 scopus 로고
    • Evidence for a role for tyrosine phosphorylation of phospholipase C72 in collagen-induced platelet cytosolic calcium mobilization
    • Daniel, J. L., Dangelmaier, C, and Smith, J. B. (1994) Evidence for a role for tyrosine phosphorylation of phospholipase C72 in collagen-induced platelet cytosolic calcium mobilization. Biochem. J. 302, 617-622
    • (1994) Biochem. J. , vol.302 , pp. 617-622
    • Daniel, J.L.1    Dangelmaier, C.2    Smith, J.B.3
  • 14
    • 0034213327 scopus 로고    scopus 로고
    • Rho GTPases and their effector proteins
    • Bishop, A. L., and Hall, A. (2000) Rho GTPases and their effector proteins. Biochem. J. 348, 241-255
    • (2000) Biochem. J. , vol.348 , pp. 241-255
    • Bishop, A.L.1    Hall, A.2
  • 15
    • 79952352658 scopus 로고    scopus 로고
    • Dynamics of the Rho-family small GTPases in actin regulation and motility
    • Spiering, D., and Hodgson, L. (2011) Dynamics of the Rho-family small GTPases in actin regulation and motility. CellAdh. Migr. 5, 170-180
    • (2011) CellAdh. Migr. , vol.5 , pp. 170-180
    • Spiering, D.1    Hodgson, L.2
  • 16
    • 0028961293 scopus 로고
    • Rho, Rac, and Cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia
    • Nobes, C. D., and Hall, A. (1995) Rho, Rac, and Cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia. Cell 81, 53-62
    • (1995) Cell , vol.81 , pp. 53-62
    • Nobes, C.D.1    Hall, A.2
  • 17
    • 0038357669 scopus 로고    scopus 로고
    • Distribution of Rho family GTPases in the adult rat hippocampus and cerebellum
    • O'Kane, E. M., Stone, T. W., and Morris, B. J. (2003) Distribution of Rho family GTPases in the adult rat hippocampus and cerebellum. Brain Res. Mol. Brain Res. 114, 1-8
    • (2003) Brain Res. Mol. Brain Res. , vol.114 , pp. 1-8
    • O'Kane, E.M.1    Stone, T.W.2    Morris, B.J.3
  • 19
    • 0026642504 scopus 로고
    • Growth-regulated expression of rhoG, a new member of the ras homolog gene family
    • Vincent, S., Jeanteur, P., and Fort, P. (1992) Growth-regulated expression of rhoG, a new member of the ras homolog gene family. Mol. Cell. Biol. 12, 3138-3148
    • (1992) Mol. Cell. Biol. , vol.12 , pp. 3138-3148
    • Vincent, S.1    Jeanteur, P.2    Fort, P.3
  • 22
    • 31644445194 scopus 로고    scopus 로고
    • Activation of Rac1 by RhoG regulates cell migration
    • Katoh, H, Hiramoto, K., and Negishi, M. (2006) Activation of Rac1 by RhoG regulates cell migration. J. CellSci. 119, 56-65
    • (2006) J. CellSci. , vol.119 , pp. 56-65
    • Katoh, H.1    Hiramoto, K.2    Negishi, M.3
  • 23
    • 0042674398 scopus 로고    scopus 로고
    • RhoG activates Rac1 by direct interaction with the Dock180-binding protein Elmo
    • Katoh, H., and Negishi, M. (2003) RhoG activates Rac1 by direct interaction with the Dock180-binding protein Elmo. Nature 424, 461-464
    • (2003) Nature , vol.424 , pp. 461-464
    • Katoh, H.1    Negishi, M.2
  • 24
    • 36448961645 scopus 로고    scopus 로고
    • Engulfment of apoptotic cells: Signals for a good meal
    • Ravichandran, K. S., and Lorenz, U. (2007) Engulfment of apoptotic cells: signals for a good meal. Nat. Rev. Immunol. 7, 964-974
    • (2007) Nat. Rev. Immunol. , vol.7 , pp. 964-974
    • Ravichandran, K.S.1    Lorenz, U.2
  • 25
    • 0035168371 scopus 로고    scopus 로고
    • Kinectin is a key effector of RhoG microtubule-dependent cellular activity
    • Vignal, E., Blangy, A., Martin, M., Gauthier-Rouvière, C, and Fort, P. (2001) Kinectin is a key effector of RhoG microtubule-dependent cellular activity. Mol. Cell. Biol. 21, 8022-8034
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 8022-8034
    • Vignal, E.1    Blangy, A.2    Martin, M.3    Gauthier-Rouvière, C.4    Fort, P.5
  • 26
    • 34547212323 scopus 로고    scopus 로고
    • RhoG regulates anoikis through a phosphatidylinositol 3-kinase-dependent mechanism
    • Yamaki, N, Negishi, M., and Katoh, H. (2007) RhoG regulates anoikis through a phosphatidylinositol 3-kinase-dependent mechanism. Exp. Cell Res. 313, 2821-2832
    • (2007) Exp. Cell Res. , vol.313 , pp. 2821-2832
    • Yamaki, N.1    Negishi, M.2    Katoh, H.3
  • 27
    • 0030801096 scopus 로고    scopus 로고
    • Convulxin, a potent platelet-aggregating protein from Crotalus durissus terrificus venom, specifically binds to platelets
    • Francischetti, I. M., Saliou, B., Leduc, M., Carlini, C. R., Hatmi, M., Randon, J., Faili, A., and Bon, C. (1997) Convulxin, a potent platelet-aggregating protein from Crotalus durissus terrificus venom, specifically binds to platelets. Toxicon 35, 1217-1228
    • (1997) Toxicon , vol.35 , pp. 1217-1228
    • Francischetti, I.M.1    Saliou, B.2    Leduc, M.3    Carlini, C.R.4    Hatmi, M.5    Randon, J.6    Faili, A.7    Bon, C.8
  • 30
    • 31544455817 scopus 로고    scopus 로고
    • Relative contribution of G-protein-coupled pathways to protease-activated receptor-mediated Akt phosphorylation in platelets
    • Kim, S., Jin, J., and Kunapuli, S. P. (2006) Relative contribution of G-protein-coupled pathways to protease-activated receptor-mediated Akt phosphorylation in platelets. Blood 107, 947-954
    • (2006) Blood , vol.107 , pp. 947-954
    • Kim, S.1    Jin, J.2    Kunapuli, S.P.3
  • 32
    • 79953007450 scopus 로고    scopus 로고
    • Syk-dependent phosphorylation of CLEC-2: A novel mechanism of hem-immunoreceptor tyrosine-based activation motif signaling
    • Séverin, S., Pollitt, A. Y., Navarro-Nuñez, L., Nash, C. A., Mourão-Sá, D., Eble, J. A., Senis, Y. A., and Watson, S. P. (2011) Syk-dependent phosphorylation of CLEC-2: a novel mechanism of hem-immunoreceptor tyrosine-based activation motif signaling. J. Biol. Chem. 286, 4107-4116
    • (2011) J. Biol. Chem. , vol.286 , pp. 4107-4116
    • Séverin, S.1    Pollitt, A.Y.2    Navarro-Nuñez, L.3    Nash, C.A.4    Mourão-Sá, D.5    Eble, J.A.6    Senis, Y.A.7    Watson, S.P.8
  • 33
    • 77955047782 scopus 로고    scopus 로고
    • GPVI and CLEC-2 in hemostasis and vascular integrity
    • Watson, S. P., Herbert, J. M., and Pollitt, A. Y. (2010) GPVI and CLEC-2 in hemostasis and vascular integrity. J. Thromb. Haemost. 8, 1456-1467
    • (2010) J. Thromb. Haemost. , vol.8 , pp. 1456-1467
    • Watson, S.P.1    Herbert, J.M.2    Pollitt, A.Y.3
  • 36
    • 27644596035 scopus 로고    scopus 로고
    • Platelets activated by collagen through the immunoreceptor tyrosine-based activation motif in the Fc receptor 7-chain play a pivotal role in the development of myocardial ischemia-reperfusion injury
    • Takaya, N, Katoh, Y., Iwabuchi, K., Hayashi, I., Konishi, H., Itoh, S., Okumura, K., Ra, C, Nagaoka, I., and Daida, H. (2005) Platelets activated by collagen through the immunoreceptor tyrosine-based activation motif in the Fc receptor 7-chain play a pivotal role in the development of myocardial ischemia-reperfusion injury. J. Mol. Cell. Cardiol. 39, 856-864
    • (2005) J. Mol. Cell. Cardiol. , vol.39 , pp. 856-864
    • Takaya, N.1    Katoh, Y.2    Iwabuchi, K.3    Hayashi, I.4    Konishi, H.5    Itoh, S.6    Okumura, K.7    Ra, C.8    Nagaoka, I.9    Daida, H.10
  • 37
    • 11144223241 scopus 로고    scopus 로고
    • Vav1 and Vav3 have critical but redundant roles in mediating platelet activation by collagen
    • Pearce, A. C, Senis, Y. A., Billadeau, D. D., Turner, M., Watson, S. P., and Vigorito, E. (2004) Vav1 and Vav3 have critical but redundant roles in mediating platelet activation by collagen. J. Biol. Chem. 279, 53955-53962
    • (2004) J. Biol. Chem. , vol.279 , pp. 53955-53962
    • Pearce, A.C.1    Senis, Y.A.2    Billadeau, D.D.3    Turner, M.4    Watson, S.P.5    Vigorito, E.6
  • 38
    • 0037111633 scopus 로고    scopus 로고
    • Vav1, but not Vav2, contributes to platelet aggregation by CRP and thrombin, but neither is required for regulation of phospholipase C
    • Pearce, A. C, Wilde, J. I., Doody, G. M., Best, D., Inoue, O., Vigorito, E., Tybulewicz, V. L., Turner, M., and Watson, S. P. (2002) Vav1, but not Vav2, contributes to platelet aggregation by CRP and thrombin, but neither is required for regulation of phospholipase C. Blood 100, 3561-3569
    • (2002) Blood , vol.100 , pp. 3561-3569
    • Pearce, A.C.1    Wilde, J.I.2    Doody, G.M.3    Best, D.4    Inoue, O.5    Vigorito, E.6    Tybulewicz, V.L.7    Turner, M.8    Watson, S.P.9
  • 39
    • 0032696592 scopus 로고    scopus 로고
    • Biological and regulatory properties of Vav-3, a new member of the Vav family of oncoproteins
    • Movilla, N, and Bustelo, X. R. (1999) Biological and regulatory properties of Vav-3, a new member of the Vav family of oncoproteins. Mol. Cell. Biol. 19, 7870-7885
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 7870-7885
    • Movilla, N.1    Bustelo, X.R.2
  • 40
    • 0032538792 scopus 로고    scopus 로고
    • Phosphorylation-dependent and constitutive activation of Rho proteins by wildtype and oncogenic Vav-2
    • Schuebel, K. E., Movilla, N, Rosa, J. L., and Bustelo, X. R. (1998) Phosphorylation-dependent and constitutive activation of Rho proteins by wildtype and oncogenic Vav-2. EMBOJ. 17, 6608-6621
    • (1998) EMBOJ. , vol.17 , pp. 6608-6621
    • Schuebel, K.E.1    Movilla, N.2    Rosa, J.L.3    Bustelo, X.R.4
  • 41
    • 84872093495 scopus 로고    scopus 로고
    • The many faces of the guaninenucleotide exchange factor Trio
    • van Rijssel, J., and van Buul, J. D. (2012) The many faces of the guaninenucleotide exchange factor Trio. CellAdh. Migr. 6, 482-487
    • (2012) CellAdh. Migr. , vol.6 , pp. 482-487
    • Van Rijssel, J.1    Van Buul, J.D.2
  • 42
    • 84873866382 scopus 로고    scopus 로고
    • Tyrosine phosphorylation of the Rho guanine nucleotide exchange factor Trio regulates netrin-1/DCC-mediated cortical axon outgrowth
    • DeGeer, J., Boudeau, J., Schmidt, S., Bedford, F., Lamarche-Vane, N, and Debant, A. (2013) Tyrosine phosphorylation of the Rho guanine nucleotide exchange factor Trio regulates netrin-1/DCC-mediated cortical axon outgrowth. Mol. Cell. Biol. 33, 739-751
    • (2013) Mol. Cell. Biol. , vol.33 , pp. 739-751
    • DeGeer, J.1    Boudeau, J.2    Schmidt, S.3    Bedford, F.4    Lamarche-Vane, N.5    Debant, A.6
  • 43
    • 0032481142 scopus 로고    scopus 로고
    • Identification of a novel integrin signaling pathway involving the kinase Syk and the guanine nucleotide exchange factor Vav1
    • Miranti, C. K., Leng, L., Maschberger, P., Brugge, J. S., and Shattil, S. J. (1998) Identification of a novel integrin signaling pathway involving the kinase Syk and the guanine nucleotide exchange factor Vav1. Curr. Biol. 8, 1289-1299
    • (1998) Curr. Biol. , vol.8 , pp. 1289-1299
    • Miranti, C.K.1    Leng, L.2    Maschberger, P.3    Brugge, J.S.4    Shattil, S.J.5
  • 44
    • 0035937128 scopus 로고    scopus 로고
    • The molecular adapter SLP-76 relays signals from platelet integrin αIIbβ3 to the actin cytoskeleton
    • Obergfell, A., Judd, B. A., del Pozo, M. A., Schwartz, M. A., Koretzky, G. A., and Shattil, S. J. (2001) The molecular adapter SLP-76 relays signals from platelet integrin αIIbβ3 to the actin cytoskeleton. J. Biol. Chem. 276, 5916-5923
    • (2001) J. Biol. Chem. , vol.276 , pp. 5916-5923
    • Obergfell, A.1    Judd, B.A.2    Del Pozo, M.A.3    Schwartz, M.A.4    Koretzky, G.A.5    Shattil, S.J.6
  • 45
    • 0034142240 scopus 로고    scopus 로고
    • Activation of the small GTPases, Rac and Cdc42, after ligation of the platelet PAR-1 receptor
    • Azim, A. C, Barkalow, K., Chou, J., and Hartwig, J. H. (2000) Activation of the small GTPases, Rac and Cdc42, after ligation of the platelet PAR-1 receptor. Blood 95, 959-964
    • (2000) Blood , vol.95 , pp. 959-964
    • Azim, A.C.1    Barkalow, K.2    Chou, J.3    Hartwig, J.H.4
  • 46
    • 0035930528 scopus 로고    scopus 로고
    • Differential regulation of Rho and Rac through heterotrimeric G-proteins and cyclic nucleotides
    • Gratacap, M. P., Payrastre, B., Nieswandt, B., and Offermanns, S. (2001) Differential regulation of Rho and Rac through heterotrimeric G-proteins and cyclic nucleotides. J. Biol. Chem. 276, 47906-47913
    • (2001) J. Biol. Chem. , vol.276 , pp. 47906-47913
    • Gratacap, M.P.1    Payrastre, B.2    Nieswandt, B.3    Offermanns, S.4
  • 47
    • 0035798144 scopus 로고    scopus 로고
    • Characterisation of Rac activation in thrombin- and collagen-stimulated human blood platelets
    • Soulet, C., Gendreau, S., Missy, K., Benard, V., Plantavid, M., and Payrastre, B. (2001) Characterisation of Rac activation in thrombin- and collagen-stimulated human blood platelets. FEBSLett. 507, 253-258
    • (2001) FEBSLett. , vol.507 , pp. 253-258
    • Soulet, C.1    Gendreau, S.2    Missy, K.3    Benard, V.4    Plantavid, M.5    Payrastre, B.6
  • 49
    • 77951082802 scopus 로고    scopus 로고
    • Phosphorylation of CLEC-2 is dependent on lipid rafts, actin polymerization, secondary mediators, and Rac
    • Pollitt, A. Y., Grygielska, B., Leblond, B., Désiré, L., Eble, J. A., and Watson, S. P. (2010) Phosphorylation of CLEC-2 is dependent on lipid rafts, actin polymerization, secondary mediators, and Rac. Blood 115, 2938-2946
    • (2010) Blood , vol.115 , pp. 2938-2946
    • Pollitt, A.Y.1    Grygielska, B.2    Leblond, B.3    Désiré, L.4    Eble, J.A.5    Watson, S.P.6
  • 50
    • 34447648178 scopus 로고    scopus 로고
    • Genetic and pharmacologic evidence that Rac1 GTPase is involved in regulation of platelet secretion and aggregation
    • Akbar, H., Kim, J., Funk, K., Cancelas, J. A., Shang, X., Chen, L., Johnson, J. F., Williams, D. A., and Zheng, Y. (2007) Genetic and pharmacologic evidence that Rac1 GTPase is involved in regulation of platelet secretion and aggregation. J. Thromb. Haemost. 5, 1747-1755
    • (2007) J. Thromb. Haemost. , vol.5 , pp. 1747-1755
    • Akbar, H.1    Kim, J.2    Funk, K.3    Cancelas, J.A.4    Shang, X.5    Chen, L.6    Johnson, J.F.7    Williams, D.A.8    Zheng, Y.9


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