Defective tubulin organization and proplatelet formation in murine megakaryocytes lacking Rac1 and Cdc42

Blood

Volumn 122, Issue 18, 2013, Pages 3178-3187

  Pleines, Irina ^a   Dütting, Sebastian ^a   Cherpokova, Deya ^a   Eckly, Anita ^b   Meyer, Imke ^c,d   Morowski, Martina ^a   Krohne, Georg ^e   Schulze, Harald ^d   Gachet, Christian ^b   Debili, Najet ^f   Brakebusch, Cord ^g   Nieswandt, Bernhard ^a  

^a UNIVERSITY HOSPITAL WÜRZBURG   (Germany)

^b UNIVERSITÉ DE STRASBOURG   (France)

^c FREIE UNIVERSITÄT BERLIN   (Germany)

^d CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^e UNIVERSITY OF WÜRZBURG   (Germany)

^f INSERM   (France)

^g UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; C REACTIVE PROTEIN; CRE RECOMBINASE; F ACTIN; FIBRINOGEN; G PROTEIN COUPLED RECEPTOR; PADGEM PROTEIN; PROTEIN CDC42; PROTEIN P70; RAC1 PROTEIN; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; THROMBOCYTE FACTOR 4; TUBULIN; RAC1 PROTEIN, HUMAN;

ACTIN POLYMERIZATION; ANIMAL CELL; ANIMAL EXPERIMENT; ARTERY THROMBOSIS; ARTICLE; BLOOD CLOTTING; CELL DIFFERENTIATION; ELECTRON MICROSCOPY; FLOW CYTOMETRY; GENE DELETION; HEMATOPOIETIC SYSTEM; HISTOLOGY; IMMUNOHISTOCHEMISTRY; IMMUNORECEPTOR TYROSINE BASED ACTIVATION MOTIF; IN VITRO STUDY; IN VIVO STUDY; KNOCKOUT MOUSE; MEGAKARYOCYTE; MICROTUBULE ASSEMBLY; MOUSE; NONHUMAN; PHENOTYPE; PLOIDY; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN FUNCTION; SCANNING ELECTRON MICROSCOPY; THROMBOCYTE COUNT; THROMBOCYTE FUNCTION; THROMBOCYTE LIFESPAN; THROMBOCYTE STRUCTURE; THROMBOCYTE VOLUME; THROMBOCYTOPENIA; THROMBOCYTOPOIESIS; TRANSMISSION ELECTRON MICROSCOPY; WESTERN BLOTTING; 129 MOUSE; ANIMAL; BLOOD; C57BL MOUSE; CONFOCAL MICROSCOPY; CYTOLOGY; CYTOSKELETON; GENETICS; HEMOSTASIS; MEGAKARYOBLAST; METABOLISM; MICROTUBULE; PSEUDOPODIUM; THROMBOSIS; ULTRASTRUCTURE; DEFICIENCY;

ANIMALS; BLOTTING, WESTERN; CDC42 GTP-BINDING PROTEIN; CYTOSKELETON; HEMOSTASIS; MEGAKARYOCYTE PROGENITOR CELLS; MEGAKARYOCYTES; MICE; MICE, 129 STRAIN; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROSCOPY, CONFOCAL; MICROSCOPY, ELECTRON, SCANNING; MICROSCOPY, ELECTRON, TRANSMISSION; MICROTUBULES; PSEUDOPODIA; RAC1 GTP-BINDING PROTEIN; THROMBOCYTOPENIA; THROMBOSIS; TUBULIN;

EID: 84888242635     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2013-03-487942     Document Type: Article

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