메뉴 건너뛰기




Volumn 94, Issue 3, 2012, Pages 526-536

The GRAF family member oligophrenin1 is a RhoGAP with BAR domain and regulates Rho GTPases in platelets

Author keywords

Cytoskeleton; GTPase activating proteins; OPHN1; Platelets; Rho GTPases

Indexed keywords

CYTOPLASM PROTEIN; OLIGOPHRENIN1; PROTEIN CDC42; RAC1 PROTEIN; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; UNCLASSIFIED DRUG;

EID: 84861404332     PISSN: 00086363     EISSN: 17553245     Source Type: Journal    
DOI: 10.1093/cvr/cvs079     Document Type: Article
Times cited : (24)

References (40)
  • 1
    • 0036851876 scopus 로고    scopus 로고
    • Platelets in atherothrombosis
    • DOI 10.1038/nm1102-1227
    • Ruggeri ZM. Platelets in atherothrombosis. Nat Med 2002;8:1227-1234. (Pubitemid 35373553)
    • (2002) Nature Medicine , vol.8 , Issue.11 , pp. 1227-1234
    • Ruggeri, Z.M.1
  • 3
    • 0032483550 scopus 로고    scopus 로고
    • Specific synergy of multiple substrate-receptor interactions in platelet thrombus formation under flow
    • DOI 10.1016/S0092-8674(00)81607-4
    • Savage B, Almus-Jacobs F, Ruggeri ZM. Specific synergy of multiple substrate-receptor interactions in platelet thrombus formation under flow. Cell 1998;94: 657-666. (Pubitemid 28427584)
    • (1998) Cell , vol.94 , Issue.5 , pp. 657-666
    • Savage, B.1    Almus-Jacobs, F.2    Ruggeri, Z.M.3
  • 5
    • 0028961293 scopus 로고
    • Rho Rac and Cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia
    • Nobes CD, Hall A. Rho, Rac, and Cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia. Cell 1995;81:53-62.
    • (1995) Cell , vol.81 , pp. 53-62
    • Nobes, C.D.1    Hall, A.2
  • 7
    • 77951459334 scopus 로고    scopus 로고
    • Multiple alterations of platelet functions dominated by increased secretion in mice lacking Cdc42 in platelets
    • Pleines I, Eckly A, Elvers M, Hagedorn I, Eliautou S, Bender M et al. Multiple alterations of platelet functions dominated by increased secretion in mice lacking Cdc42 in platelets. Blood 2010;115:3364-3373.
    • (2010) Blood , vol.115 , pp. 3364-3373
    • Pleines, I.1    Eckly, A.2    Elvers, M.3    Hagedorn, I.4    Eliautou, S.5    Bender, M.6
  • 8
    • 50149083752 scopus 로고    scopus 로고
    • Mammalian Rho GTPases: New insights into their functions from in vivo studies
    • Heasman SJ, Ridley AJ. Mammalian Rho GTPases: new insights into their functions from in vivo studies. Nat Rev Mol Cell Biol 2008;9:690-701.
    • (2008) Nat Rev Mol Cell Biol , vol.9 , pp. 690-701
    • Heasman, S.J.1    Ridley, A.J.2
  • 9
    • 28244447739 scopus 로고    scopus 로고
    • GTPase activating proteins: Structural and functional insights 18 years after discovery
    • DOI 10.1007/s00018-005-5136-x
    • Scheffzek K, Ahmadian M. GTPase activating proteins: structural and functional insights 18 years after discovery. Cell Mol Life Sci 2005;62:3014-3038. (Pubitemid 43004752)
    • (2005) Cellular and Molecular Life Sciences , vol.62 , Issue.24 , pp. 3014-3038
    • Scheffzek, K.1    Ahmadian, M.R.2
  • 12
    • 1842455769 scopus 로고    scopus 로고
    • The X-linked mental retardation protein oligophrenin-1 is required for dendritic spine morphogenesis
    • DOI 10.1038/nn1210
    • Govek EE, Newey SE, Akerman CJ, Cross JR, Van der Veken L, Van Aelst L. The X-linked mental retardation protein oligophrenin-1 is required for dendritic spine morphogenesis. Nat Neurosci 2004;7:364-372. (Pubitemid 38429176)
    • (2004) Nature Neuroscience , vol.7 , Issue.4 , pp. 364-372
    • Govek, E.-E.1    Newey, S.E.2    Akerman, C.J.3    Cross, J.R.4    Der Veken, L.V.5    Van Aelst, L.6
  • 14
    • 1442317538 scopus 로고    scopus 로고
    • BAR Domains as Sensors of Membrane Curvature: The Amphiphysin BAR Structure
    • DOI 10.1126/science.1092586
    • Peter BJ, Kent HM, Mills IG, Vallis Y, Butler PJG, Evans PR et al. BAR domains as sensors of membrane curvature: the amphiphysin BAR structure. Science 2004;303: 495-499. (Pubitemid 38120842)
    • (2004) Science , vol.303 , Issue.5657 , pp. 495-499
    • Peter, B.J.1    Kent, H.M.2    Mills, I.G.3    Vallis, Y.4    Butler, P.J.G.5    Evans, P.R.6    McMahon, H.T.7
  • 17
    • 0026564426 scopus 로고
    • Characterization of a gain of function mutation of integrin-alpha-IIb- beta-3 (platelet glycoprotein-IIb-IIIa)
    • Bajt ML, Loftus JC, Gawaz MP, Ginsberg MH. Characterization of a gain of function mutation of integrin-alpha-IIb-beta-3 (platelet glycoprotein-IIb-IIIa). J Biol Chem 1992;267:22211-22216.
    • (1992) J Biol Chem , vol.267 , pp. 22211-22216
    • Bajt, M.L.1    Loftus, J.C.2    Gawaz, M.P.3    Ginsberg, M.H.4
  • 18
    • 0025923720 scopus 로고
    • Platelet glycoprotein-IIb-IIIa (alpha-IIb-beta-3 integrin) confers fibrinogen-dependent and activation-dependent aggregation on heterologous cells
    • Frojmovic MM, Otoole TE, Plow EF, Loftus JC, Ginsberg MH. Platelet glycoprotein-IIb-IIIa (alpha-IIb-beta-3 integrin) confers fibrinogen-dependent and activation-dependent aggregation on heterologous cells. Blood 1991;78:369-376.
    • (1991) Blood , vol.78 , pp. 369-376
    • Frojmovic, M.M.1    Otoole, T.E.2    Plow, E.F.3    Loftus, J.C.4    Ginsberg, M.H.5
  • 19
    • 0026077672 scopus 로고
    • Ligand bridging mediates integrin alpha-IIb-beta-3 (platelet GPIIb-IIIa) dependent homotypic and heterotypic cell-cell interactions
    • Gawaz MP, Loftus JC, Bajt ML, Frojmovic MM, Plow EF, Ginsberg MH. Ligand bridging mediates integrin alpha-IIb-beta-3 (platelet GPIIb-IIIa) dependent homotypic and heterotypic cell-cell interactions. J Clin Invest 1991;88:1128-1134.
    • (1991) J Clin Invest , vol.88 , pp. 1128-1134
    • Gawaz, M.P.1    Loftus, J.C.2    Bajt, M.L.3    Frojmovic, M.M.4    Plow, E.F.5    Ginsberg, M.H.6
  • 20
    • 0025519981 scopus 로고
    • Affinity modulation of the alpha-IIb-beta-3 integrin (platelet GPIIb-IIIa) is an intrinsic property of the receptor
    • Otoole TE, Loftus JC, Du XP, Glass AA, Ruggeri ZM, Shattil SJ et al. Affinity modulation of the alpha-IIb-beta-3 integrin (platelet GPIIb-IIIa) is an intrinsic property of the receptor. Cell Regul 1990;1:883-893.
    • (1990) Cell Regul , vol.1 , pp. 883-893
    • Otoole, T.E.1    Loftus, J.C.2    Du, X.P.3    Glass, A.A.4    Ruggeri, Z.M.5    Shattil, S.J.6
  • 21
    • 0842281652 scopus 로고    scopus 로고
    • Rho and Rac Take Center Stage
    • DOI 10.1016/S0092-8674(04)00003-0
    • Burridge K, Wennerberg K. Rho and Rac take center stage. Cell 2004;116: 167-179. (Pubitemid 38167310)
    • (2004) Cell , vol.116 , Issue.2 , pp. 167-179
    • Burridge, K.1    Wennerberg, K.2
  • 22
    • 77954485876 scopus 로고    scopus 로고
    • Platelet hyperreactivity and a prothrombotic phenotype in mice with a gain-of-function mutation in phospholipase C gamma 2
    • Elvers M, Pozgaj R, Pleines I, May F, Kuijpers MJE, Heemskerk JMW et al. Platelet hyperreactivity and a prothrombotic phenotype in mice with a gain-of-function mutation in phospholipase C gamma 2. J Thromb Haemost 2010;8:1353-1363.
    • (2010) J Thromb Haemost , vol.8 , pp. 1353-1363
    • Elvers, M.1    Pozgaj, R.2    Pleines, I.3    May, F.4    Kuijpers, M.J.E.5    Heemskerk, J.M.W.6
  • 23
    • 33746800269 scopus 로고    scopus 로고
    • Focal adhesions: What's new inside
    • DOI 10.1016/j.ydbio.2006.03.029, PII S0012160606002314
    • Lo SH. Focal adhesions: what's new inside. Dev Biol 2006;294:280-291. (Pubitemid 44172878)
    • (2006) Developmental Biology , vol.294 , Issue.2 , pp. 280-291
    • Lo, S.H.1
  • 25
    • 3042796979 scopus 로고    scopus 로고
    • GAP control: Regulating the regulators of small GTPases
    • DOI 10.1016/j.tcb.2004.05.003, PII S0962892404001357
    • Bernards A, Settleman J. GAP control: regulating the regulators of small GTPases. Trends Cell Biol 2004;14:377-385. (Pubitemid 38891707)
    • (2004) Trends in Cell Biology , vol.14 , Issue.7 , pp. 377-385
    • Bernards, A.1    Settleman, J.2
  • 26
    • 24944582633 scopus 로고    scopus 로고
    • GAPs in growth factor signalling
    • DOI 10.1080/08977190500130480, PII QX141777445075
    • Bernards A, Settleman J. GAPs in growth factor signalling. Growth Factors 2005;23: 143-149. (Pubitemid 43203062)
    • (2005) Growth Factors , vol.23 , Issue.2 , pp. 143-149
    • Bernards, A.1    Settleman, J.2
  • 27
    • 0037213689 scopus 로고    scopus 로고
    • Rho GTPase-activating proteins in cell regulation
    • DOI 10.1016/S0962-8924(02)00004-1, PII S0962892402000041
    • Moon SY, Zheng Y. Rho GTPase-activating proteins in cell regulation. Trends Cell Biol 2003;13:13-22. (Pubitemid 35453891)
    • (2003) Trends in Cell Biology , vol.13 , Issue.1 , pp. 13-22
    • Moon, S.Y.1    Zheng, Y.2
  • 28
    • 2542493836 scopus 로고    scopus 로고
    • A Shear-restricted pathway of platelet procoagulant activity is regulate by IQGAP1
    • DOI 10.1074/jbc.M402561200
    • Bahou WF, Scudder L, Rubenstein D, Jesty J. A shear-restricted pathway of platelet procoagulant activity is regulated by IQGAP1. J Biol Chem 2004;279: 22571-22577. (Pubitemid 38679457)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.21 , pp. 22571-22577
    • Bahou, W.F.1    Scudder, L.2    Rubenstein, D.3    Jesty, J.4
  • 29
    • 0038620337 scopus 로고    scopus 로고
    • IQGAP2 functions as a GTP-dependent effector protein in thrombin-induced platelet cytoskeletal reorganization
    • DOI 10.1182/blood-2002-09-2807
    • Schmidt VA, Scudder L, Devoe CE, Bernards A, Cupit LD, Bahou WF. IQGAP2 functions as a GTP dependent effector protein in thrombin-induced platelet cytoskeletal reorganization. Blood 2003;101:3021-3028. (Pubitemid 36857990)
    • (2003) Blood , vol.101 , Issue.8 , pp. 3021-3028
    • Schmidt, V.A.1    Scudder, L.2    Devoe, C.E.3    Bernards, A.4    Cupit, L.D.5    Bahou, W.F.6
  • 30
    • 74549184087 scopus 로고    scopus 로고
    • G protein subunit G alpha(13) binds to integrin alpha(IIb)beta(3) and mediates integrin 'outside-in' signaling
    • Gong HX, Shen B, Flevaris P, Chow C, Lam SCT, Voyno-Yasenetskaya TA et al. G protein subunit G alpha(13) binds to integrin alpha(IIb)beta(3) and mediates integrin 'outside-in' signaling. Science 2010;327:340-343.
    • (2010) Science , vol.327 , pp. 340-343
    • Gong, H.X.1    Shen, B.2    Flevaris, P.3    Chow, C.4    Lam, S.C.T.5    Voyno-Yasenetskaya, T.A.6
  • 32
    • 77953519106 scopus 로고    scopus 로고
    • P190RhoGAP and Rap-dependent RhoGAP (ARAP3) inactivate RhoA in response to nerve growth factor leading to neurite outgrowth from PC12 cells
    • Jeon CY, Kim HJ, Lee JY, Kim J, Kim SC, Park JB. p190RhoGAP and Rap-dependent RhoGAP (ARAP3) inactivate RhoA in response to nerve growth factor leading to neurite outgrowth from PC12 cells. Exp Mol Med 2010;42:335-344.
    • (2010) Exp Mol Med , vol.42 , pp. 335-344
    • Jeon, C.Y.1    Kim, H.J.2    Lee, J.Y.3    Kim, J.4    Kim, S.C.5    Park, J.B.6
  • 33
    • 68549130674 scopus 로고    scopus 로고
    • Role of DLC-1, a tumor suppressor protein with RhoGAP activity, in regulation of the cytoskeleton and cell motility
    • Kim T, Vigil D, Der C, Juliano R. Role of DLC-1, a tumor suppressor protein with RhoGAP activity, in regulation of the cytoskeleton and cell motility. Cancer Metastasis Rev 2009;28:77-83.
    • (2009) Cancer Metastasis Rev , vol.28 , pp. 77-83
    • Kim, T.1    Vigil, D.2    Der Juliano C, R.3
  • 35
    • 0029955660 scopus 로고    scopus 로고
    • An SH3 domain-containing GTPase-activating protein for Rho and Cdc42 associates with focal adhesion kinase
    • Hildebrand JD, Taylor JM, Parsons JT. An SH3 domain-containing GTPase-activating protein for Rho and Cdc42 associates with focal adhesion kinase. Mol Cell Biol 1996;16:3169-3178. (Pubitemid 26163383)
    • (1996) Molecular and Cellular Biology , vol.16 , Issue.6 , pp. 3169-3178
    • Hildebrand, J.D.1    Taylor, J.M.2    Thomas Parsons, J.3
  • 36
    • 0032991640 scopus 로고    scopus 로고
    • Cytoskeletal changes induced by GRAF, the GTPase regulator associated with focal adhesion kinase, are mediated by Rho
    • Taylor JM, Macklem MM, Parsons JT. Cytoskeletal changes induced by GRAF, the GTPase regulator associated with focal adhesion kinase, are mediated by Rho. J Cell Sci 1999;112:231-242. (Pubitemid 29078357)
    • (1999) Journal of Cell Science , vol.112 , Issue.2 , pp. 231-242
    • Taylor, J.M.1    Macklem, M.M.2    Parsons, J.T.3
  • 38
    • 62149105253 scopus 로고    scopus 로고
    • DLC1 interacts with 14-3-3 proteins to inhibit RhoGAP activity and block nucleocytoplasmic shuttling
    • Scholz RP, Regner J, Theil A, Erlmann P, Holeiter G, Jahne R et al. DLC1 interacts with 14-3-3 proteins to inhibit RhoGAP activity and block nucleocytoplasmic shuttling. J Cell Sci 2009;122:92-102.
    • (2009) J Cell Sci , vol.122 , pp. 92-102
    • Scholz, R.P.1    Regner, J.2    Theil, A.3    Erlmann, P.4    Holeiter, G.5    Jahne, R.6
  • 39
    • 0034659526 scopus 로고    scopus 로고
    • Integrin engagement suppresses RhoA activity via a c-Src-dependent mechanism
    • DOI 10.1016/S0960-9822(00)00537-6
    • Arthur WT, Petch LA, Burridge K. Integrin engagement suppresses RhoA activity via a c-Src-dependent mechanism. Curr Biol 2000;10:719-722. (Pubitemid 30437944)
    • (2000) Current Biology , vol.10 , Issue.12 , pp. 719-722
    • Arthur, W.T.1    Petch, L.A.2    Burridge, K.3
  • 40
    • 33847419281 scopus 로고    scopus 로고
    • Filamin links cell shape and cytoskeletal structure to Rho regulation by controlling accumulation of p190RhoGAP in lipid rafts
    • DOI 10.1242/jcs.03353
    • Mammoto A, Huang S, Ingber DE. Filamin links cell shape and cytoskeletal structure to Rho regulation by controlling accumulation of p190RhoGAP in lipid rafts. J Cell Sci 2007;120:456-467. (Pubitemid 46332509)
    • (2007) Journal of Cell Science , vol.120 , Issue.3 , pp. 456-467
    • Mammoto, A.1    Huang, S.2    Ingber, D.E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.