-
1
-
-
0036851876
-
Platelets in atherothrombosis
-
DOI 10.1038/nm1102-1227
-
Ruggeri ZM. Platelets in atherothrombosis. Nat Med 2002;8:1227-1234. (Pubitemid 35373553)
-
(2002)
Nature Medicine
, vol.8
, Issue.11
, pp. 1227-1234
-
-
Ruggeri, Z.M.1
-
3
-
-
0032483550
-
Specific synergy of multiple substrate-receptor interactions in platelet thrombus formation under flow
-
DOI 10.1016/S0092-8674(00)81607-4
-
Savage B, Almus-Jacobs F, Ruggeri ZM. Specific synergy of multiple substrate-receptor interactions in platelet thrombus formation under flow. Cell 1998;94: 657-666. (Pubitemid 28427584)
-
(1998)
Cell
, vol.94
, Issue.5
, pp. 657-666
-
-
Savage, B.1
Almus-Jacobs, F.2
Ruggeri, Z.M.3
-
5
-
-
0028961293
-
Rho Rac and Cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia
-
Nobes CD, Hall A. Rho, Rac, and Cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia. Cell 1995;81:53-62.
-
(1995)
Cell
, vol.81
, pp. 53-62
-
-
Nobes, C.D.1
Hall, A.2
-
6
-
-
59849108084
-
Rac1 is essential for phospholipase C-gamma 2 activation in platelets
-
Pleines I, Elvers M, Strehl A, Pozgajova M, Varga-Szabo D, May F et al. Rac1 is essential for phospholipase C-gamma 2 activation in platelets. Pflugers Arch 2009;457: 1173-1185.
-
(2009)
Pflugers Arch
, vol.457
, pp. 1173-1185
-
-
Pleines, I.1
Elvers, M.2
Strehl, A.3
Pozgajova, M.4
Varga-Szabo, D.5
May, F.6
-
7
-
-
77951459334
-
Multiple alterations of platelet functions dominated by increased secretion in mice lacking Cdc42 in platelets
-
Pleines I, Eckly A, Elvers M, Hagedorn I, Eliautou S, Bender M et al. Multiple alterations of platelet functions dominated by increased secretion in mice lacking Cdc42 in platelets. Blood 2010;115:3364-3373.
-
(2010)
Blood
, vol.115
, pp. 3364-3373
-
-
Pleines, I.1
Eckly, A.2
Elvers, M.3
Hagedorn, I.4
Eliautou, S.5
Bender, M.6
-
8
-
-
50149083752
-
Mammalian Rho GTPases: New insights into their functions from in vivo studies
-
Heasman SJ, Ridley AJ. Mammalian Rho GTPases: new insights into their functions from in vivo studies. Nat Rev Mol Cell Biol 2008;9:690-701.
-
(2008)
Nat Rev Mol Cell Biol
, vol.9
, pp. 690-701
-
-
Heasman, S.J.1
Ridley, A.J.2
-
9
-
-
28244447739
-
GTPase activating proteins: Structural and functional insights 18 years after discovery
-
DOI 10.1007/s00018-005-5136-x
-
Scheffzek K, Ahmadian M. GTPase activating proteins: structural and functional insights 18 years after discovery. Cell Mol Life Sci 2005;62:3014-3038. (Pubitemid 43004752)
-
(2005)
Cellular and Molecular Life Sciences
, vol.62
, Issue.24
, pp. 3014-3038
-
-
Scheffzek, K.1
Ahmadian, M.R.2
-
10
-
-
0032580161
-
Oligophrenin-1 encodes a rhoGAP protein involved in X-linked mental retardation
-
DOI 10.1038/31940
-
Billuart P, Bienvenu T, Ronce N, Des Portes V, Vinet MC, Zemni R et al. Oligophrenin-1 encodes a rhoGAP protein involved in X-linked mental retardation. Nature 1998;392:923-926. (Pubitemid 28232063)
-
(1998)
Nature
, vol.392
, Issue.6679
, pp. 923-926
-
-
Billuart, P.1
Bienvenu, T.2
Roncet, N.3
Des Portes, V.4
Vinet, M.C.5
Zemni, R.6
Crollius, H.R.7
Carrie, A.8
Fauchereau, F.9
Cherry, M.10
Briault, S.11
Hamel, B.12
Fryns, J.-P.13
Beldjord, C.14
Kahn, A.15
Moraine, C.16
Chelly, J.17
-
11
-
-
0043162110
-
The RhoGAP activity of OPHN1, a new F-actin-binding protein, is negatively controlled by its amino-terminal domain
-
DOI 10.1016/S1044-7431(03)00078-2
-
Fauchereau F, Herbrand U, Chafey P, Eberth A, Koulakoff A, Vinet MC et al. The RhoGAP activity of OPHN1, a new F-actin-binding protein, is negatively controlled by its amino-terminal domain. Mol Cell Neurosci 2003;23:574-586. (Pubitemid 36970219)
-
(2003)
Molecular and Cellular Neuroscience
, vol.23
, Issue.4
, pp. 574-586
-
-
Fauchereau, F.1
Herbrand, U.2
Chafey, P.3
Eberth, A.4
Koulakoff, A.5
Vinet, M.-C.6
Ahmadian, M.R.7
Chelly, J.8
Billuart, P.9
-
12
-
-
1842455769
-
The X-linked mental retardation protein oligophrenin-1 is required for dendritic spine morphogenesis
-
DOI 10.1038/nn1210
-
Govek EE, Newey SE, Akerman CJ, Cross JR, Van der Veken L, Van Aelst L. The X-linked mental retardation protein oligophrenin-1 is required for dendritic spine morphogenesis. Nat Neurosci 2004;7:364-372. (Pubitemid 38429176)
-
(2004)
Nature Neuroscience
, vol.7
, Issue.4
, pp. 364-372
-
-
Govek, E.-E.1
Newey, S.E.2
Akerman, C.J.3
Cross, J.R.4
Der Veken, L.V.5
Van Aelst, L.6
-
13
-
-
58249084134
-
A BAR domain-mediated autoinhibitory mechanism for RhoGAPs of the GRAF family
-
Eberth A, Lundmark R, Gremer L, Dvorsky R, Koessmeier KT, McMahon HT et al. A BAR domain-mediated autoinhibitory mechanism for RhoGAPs of the GRAF family. Biochem J 2009;417:371-377.
-
(2009)
Biochem J
, vol.417
, pp. 371-377
-
-
Eberth, A.1
Lundmark, R.2
Gremer, L.3
Dvorsky, R.4
Koessmeier, K.T.5
McMahon, H.T.6
-
14
-
-
1442317538
-
BAR Domains as Sensors of Membrane Curvature: The Amphiphysin BAR Structure
-
DOI 10.1126/science.1092586
-
Peter BJ, Kent HM, Mills IG, Vallis Y, Butler PJG, Evans PR et al. BAR domains as sensors of membrane curvature: the amphiphysin BAR structure. Science 2004;303: 495-499. (Pubitemid 38120842)
-
(2004)
Science
, vol.303
, Issue.5657
, pp. 495-499
-
-
Peter, B.J.1
Kent, H.M.2
Mills, I.G.3
Vallis, Y.4
Butler, P.J.G.5
Evans, P.R.6
McMahon, H.T.7
-
15
-
-
34548450836
-
Loss of X-linked mental retardation gene oligophrenin1 in mice impairs spatial memory and leads to ventricular enlargement and dendritic spine immaturity
-
DOI 10.1523/JNEUROSCI.2029-07.2007
-
Khelfaoui M, Denis C, van Galen E, de Bock F, Schmitt A, Houbron C et al. Loss of X-linked mental retardation gene oligophrenin 1 in mice impairs spatial memory and leads to ventricular enlargement and dendritic spine immaturity. J Neurosci 2007;27:9439-9450. (Pubitemid 47358207)
-
(2007)
Journal of Neuroscience
, vol.27
, Issue.35
, pp. 9439-9450
-
-
Khelfaoui, M.1
Denis, C.2
Van Galen, E.3
De Bock, F.4
Schmitt, A.5
Houbron, C.6
Morice, E.7
Giros, B.8
Ramakers, G.9
Fagni, L.10
Chelly, J.11
Nosten-Bertrand, M.12
Billuart, P.13
-
17
-
-
0026564426
-
Characterization of a gain of function mutation of integrin-alpha-IIb- beta-3 (platelet glycoprotein-IIb-IIIa)
-
Bajt ML, Loftus JC, Gawaz MP, Ginsberg MH. Characterization of a gain of function mutation of integrin-alpha-IIb-beta-3 (platelet glycoprotein-IIb-IIIa). J Biol Chem 1992;267:22211-22216.
-
(1992)
J Biol Chem
, vol.267
, pp. 22211-22216
-
-
Bajt, M.L.1
Loftus, J.C.2
Gawaz, M.P.3
Ginsberg, M.H.4
-
18
-
-
0025923720
-
Platelet glycoprotein-IIb-IIIa (alpha-IIb-beta-3 integrin) confers fibrinogen-dependent and activation-dependent aggregation on heterologous cells
-
Frojmovic MM, Otoole TE, Plow EF, Loftus JC, Ginsberg MH. Platelet glycoprotein-IIb-IIIa (alpha-IIb-beta-3 integrin) confers fibrinogen-dependent and activation-dependent aggregation on heterologous cells. Blood 1991;78:369-376.
-
(1991)
Blood
, vol.78
, pp. 369-376
-
-
Frojmovic, M.M.1
Otoole, T.E.2
Plow, E.F.3
Loftus, J.C.4
Ginsberg, M.H.5
-
19
-
-
0026077672
-
Ligand bridging mediates integrin alpha-IIb-beta-3 (platelet GPIIb-IIIa) dependent homotypic and heterotypic cell-cell interactions
-
Gawaz MP, Loftus JC, Bajt ML, Frojmovic MM, Plow EF, Ginsberg MH. Ligand bridging mediates integrin alpha-IIb-beta-3 (platelet GPIIb-IIIa) dependent homotypic and heterotypic cell-cell interactions. J Clin Invest 1991;88:1128-1134.
-
(1991)
J Clin Invest
, vol.88
, pp. 1128-1134
-
-
Gawaz, M.P.1
Loftus, J.C.2
Bajt, M.L.3
Frojmovic, M.M.4
Plow, E.F.5
Ginsberg, M.H.6
-
20
-
-
0025519981
-
Affinity modulation of the alpha-IIb-beta-3 integrin (platelet GPIIb-IIIa) is an intrinsic property of the receptor
-
Otoole TE, Loftus JC, Du XP, Glass AA, Ruggeri ZM, Shattil SJ et al. Affinity modulation of the alpha-IIb-beta-3 integrin (platelet GPIIb-IIIa) is an intrinsic property of the receptor. Cell Regul 1990;1:883-893.
-
(1990)
Cell Regul
, vol.1
, pp. 883-893
-
-
Otoole, T.E.1
Loftus, J.C.2
Du, X.P.3
Glass, A.A.4
Ruggeri, Z.M.5
Shattil, S.J.6
-
21
-
-
0842281652
-
Rho and Rac Take Center Stage
-
DOI 10.1016/S0092-8674(04)00003-0
-
Burridge K, Wennerberg K. Rho and Rac take center stage. Cell 2004;116: 167-179. (Pubitemid 38167310)
-
(2004)
Cell
, vol.116
, Issue.2
, pp. 167-179
-
-
Burridge, K.1
Wennerberg, K.2
-
22
-
-
77954485876
-
Platelet hyperreactivity and a prothrombotic phenotype in mice with a gain-of-function mutation in phospholipase C gamma 2
-
Elvers M, Pozgaj R, Pleines I, May F, Kuijpers MJE, Heemskerk JMW et al. Platelet hyperreactivity and a prothrombotic phenotype in mice with a gain-of-function mutation in phospholipase C gamma 2. J Thromb Haemost 2010;8:1353-1363.
-
(2010)
J Thromb Haemost
, vol.8
, pp. 1353-1363
-
-
Elvers, M.1
Pozgaj, R.2
Pleines, I.3
May, F.4
Kuijpers, M.J.E.5
Heemskerk, J.M.W.6
-
23
-
-
33746800269
-
Focal adhesions: What's new inside
-
DOI 10.1016/j.ydbio.2006.03.029, PII S0012160606002314
-
Lo SH. Focal adhesions: what's new inside. Dev Biol 2006;294:280-291. (Pubitemid 44172878)
-
(2006)
Developmental Biology
, vol.294
, Issue.2
, pp. 280-291
-
-
Lo, S.H.1
-
25
-
-
3042796979
-
GAP control: Regulating the regulators of small GTPases
-
DOI 10.1016/j.tcb.2004.05.003, PII S0962892404001357
-
Bernards A, Settleman J. GAP control: regulating the regulators of small GTPases. Trends Cell Biol 2004;14:377-385. (Pubitemid 38891707)
-
(2004)
Trends in Cell Biology
, vol.14
, Issue.7
, pp. 377-385
-
-
Bernards, A.1
Settleman, J.2
-
26
-
-
24944582633
-
GAPs in growth factor signalling
-
DOI 10.1080/08977190500130480, PII QX141777445075
-
Bernards A, Settleman J. GAPs in growth factor signalling. Growth Factors 2005;23: 143-149. (Pubitemid 43203062)
-
(2005)
Growth Factors
, vol.23
, Issue.2
, pp. 143-149
-
-
Bernards, A.1
Settleman, J.2
-
27
-
-
0037213689
-
Rho GTPase-activating proteins in cell regulation
-
DOI 10.1016/S0962-8924(02)00004-1, PII S0962892402000041
-
Moon SY, Zheng Y. Rho GTPase-activating proteins in cell regulation. Trends Cell Biol 2003;13:13-22. (Pubitemid 35453891)
-
(2003)
Trends in Cell Biology
, vol.13
, Issue.1
, pp. 13-22
-
-
Moon, S.Y.1
Zheng, Y.2
-
28
-
-
2542493836
-
A Shear-restricted pathway of platelet procoagulant activity is regulate by IQGAP1
-
DOI 10.1074/jbc.M402561200
-
Bahou WF, Scudder L, Rubenstein D, Jesty J. A shear-restricted pathway of platelet procoagulant activity is regulated by IQGAP1. J Biol Chem 2004;279: 22571-22577. (Pubitemid 38679457)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.21
, pp. 22571-22577
-
-
Bahou, W.F.1
Scudder, L.2
Rubenstein, D.3
Jesty, J.4
-
29
-
-
0038620337
-
IQGAP2 functions as a GTP-dependent effector protein in thrombin-induced platelet cytoskeletal reorganization
-
DOI 10.1182/blood-2002-09-2807
-
Schmidt VA, Scudder L, Devoe CE, Bernards A, Cupit LD, Bahou WF. IQGAP2 functions as a GTP dependent effector protein in thrombin-induced platelet cytoskeletal reorganization. Blood 2003;101:3021-3028. (Pubitemid 36857990)
-
(2003)
Blood
, vol.101
, Issue.8
, pp. 3021-3028
-
-
Schmidt, V.A.1
Scudder, L.2
Devoe, C.E.3
Bernards, A.4
Cupit, L.D.5
Bahou, W.F.6
-
30
-
-
74549184087
-
G protein subunit G alpha(13) binds to integrin alpha(IIb)beta(3) and mediates integrin 'outside-in' signaling
-
Gong HX, Shen B, Flevaris P, Chow C, Lam SCT, Voyno-Yasenetskaya TA et al. G protein subunit G alpha(13) binds to integrin alpha(IIb)beta(3) and mediates integrin 'outside-in' signaling. Science 2010;327:340-343.
-
(2010)
Science
, vol.327
, pp. 340-343
-
-
Gong, H.X.1
Shen, B.2
Flevaris, P.3
Chow, C.4
Lam, S.C.T.5
Voyno-Yasenetskaya, T.A.6
-
31
-
-
0037177816
-
3 adhesion contacts under high shear
-
DOI 10.1074/jbc.M200661200
-
Schoenwaelder SM, Hughan SC, Boniface K, Fernando S, Holdsworth M, Thompson PE et al. RhoA sustains integrin alpha(IIb)beta(3) adhesion contacts under high shear. J Biol Chem 2002;277:14738-14746. (Pubitemid 34952545)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.17
, pp. 14738-14746
-
-
Schoenwaelder, S.M.1
Hughan, S.C.2
Boniface, K.3
Fernando, S.4
Holdsworth, M.5
Thompson, P.E.6
Salem, H.H.7
Jackson, S.P.8
-
32
-
-
77953519106
-
P190RhoGAP and Rap-dependent RhoGAP (ARAP3) inactivate RhoA in response to nerve growth factor leading to neurite outgrowth from PC12 cells
-
Jeon CY, Kim HJ, Lee JY, Kim J, Kim SC, Park JB. p190RhoGAP and Rap-dependent RhoGAP (ARAP3) inactivate RhoA in response to nerve growth factor leading to neurite outgrowth from PC12 cells. Exp Mol Med 2010;42:335-344.
-
(2010)
Exp Mol Med
, vol.42
, pp. 335-344
-
-
Jeon, C.Y.1
Kim, H.J.2
Lee, J.Y.3
Kim, J.4
Kim, S.C.5
Park, J.B.6
-
33
-
-
68549130674
-
Role of DLC-1, a tumor suppressor protein with RhoGAP activity, in regulation of the cytoskeleton and cell motility
-
Kim T, Vigil D, Der C, Juliano R. Role of DLC-1, a tumor suppressor protein with RhoGAP activity, in regulation of the cytoskeleton and cell motility. Cancer Metastasis Rev 2009;28:77-83.
-
(2009)
Cancer Metastasis Rev
, vol.28
, pp. 77-83
-
-
Kim, T.1
Vigil, D.2
Der Juliano C, R.3
-
34
-
-
12944277168
-
The human GRAF gene is fused to MLL in a unique t(5;11)(q31;q23) and both alleles are disrupted in three cases of myelodysplastic syndrome/acute myeloid leukemia with a deletion 5q
-
DOI 10.1073/pnas.150079597
-
Borkhardt A, Bojesen S, Haas OA, Fuchs U, Bartelheimer D, Loncarevic IF et al. The human GRAF gene is fused to MLL in a unique t(5;11)(q31;q23) and both alleles are disrupted in three cases of myelodysplastic syndrome/acute myeloid leukemia with a deletion 5q. Proc Natl Acad Sci USA 2000;97: 9168-9173. (Pubitemid 30626692)
-
(2000)
Proceedings of the National Academy of Sciences of the United States of America
, vol.97
, Issue.16
, pp. 9168-9173
-
-
Borkhardt, A.1
Bojesen, S.2
Haas, O.A.3
Fuchs, U.4
Bartelheimer, D.5
Loncarevic, I.F.6
Bohle, R.M.7
Harbott, J.8
Repp, R.9
Jaeger, U.10
Viehmann, S.11
Henn, T.12
Korth, P.13
Scharr, D.14
Lampert, F.15
-
35
-
-
0029955660
-
An SH3 domain-containing GTPase-activating protein for Rho and Cdc42 associates with focal adhesion kinase
-
Hildebrand JD, Taylor JM, Parsons JT. An SH3 domain-containing GTPase-activating protein for Rho and Cdc42 associates with focal adhesion kinase. Mol Cell Biol 1996;16:3169-3178. (Pubitemid 26163383)
-
(1996)
Molecular and Cellular Biology
, vol.16
, Issue.6
, pp. 3169-3178
-
-
Hildebrand, J.D.1
Taylor, J.M.2
Thomas Parsons, J.3
-
36
-
-
0032991640
-
Cytoskeletal changes induced by GRAF, the GTPase regulator associated with focal adhesion kinase, are mediated by Rho
-
Taylor JM, Macklem MM, Parsons JT. Cytoskeletal changes induced by GRAF, the GTPase regulator associated with focal adhesion kinase, are mediated by Rho. J Cell Sci 1999;112:231-242. (Pubitemid 29078357)
-
(1999)
Journal of Cell Science
, vol.112
, Issue.2
, pp. 231-242
-
-
Taylor, J.M.1
Macklem, M.M.2
Parsons, J.T.3
-
37
-
-
22144456726
-
Regulation of ASAP1 by phospholipids is dependent on the interface between the PH and Arf GAP domains
-
DOI 10.1016/j.cellsig.2005.01.007, PII S0898656805000173
-
Che MM, Boja ES, Yoon HY, Gruschus J, Jaffe H, Stauffer S et al. Regulation of ASAP1 by phospholipids is dependent on the interface between the PH and Arf GAP domains. Cell Signal 2005;17:1276-1288. (Pubitemid 40984038)
-
(2005)
Cellular Signalling
, vol.17
, Issue.10
, pp. 1276-1288
-
-
Che, M.M.1
Boja, E.S.2
Yoon, H.-Y.3
Gruschus, J.4
Jaffe, H.5
Stauffer, S.6
Schuck, P.7
Fales, H.M.8
Randazzo, P.A.9
-
38
-
-
62149105253
-
DLC1 interacts with 14-3-3 proteins to inhibit RhoGAP activity and block nucleocytoplasmic shuttling
-
Scholz RP, Regner J, Theil A, Erlmann P, Holeiter G, Jahne R et al. DLC1 interacts with 14-3-3 proteins to inhibit RhoGAP activity and block nucleocytoplasmic shuttling. J Cell Sci 2009;122:92-102.
-
(2009)
J Cell Sci
, vol.122
, pp. 92-102
-
-
Scholz, R.P.1
Regner, J.2
Theil, A.3
Erlmann, P.4
Holeiter, G.5
Jahne, R.6
-
39
-
-
0034659526
-
Integrin engagement suppresses RhoA activity via a c-Src-dependent mechanism
-
DOI 10.1016/S0960-9822(00)00537-6
-
Arthur WT, Petch LA, Burridge K. Integrin engagement suppresses RhoA activity via a c-Src-dependent mechanism. Curr Biol 2000;10:719-722. (Pubitemid 30437944)
-
(2000)
Current Biology
, vol.10
, Issue.12
, pp. 719-722
-
-
Arthur, W.T.1
Petch, L.A.2
Burridge, K.3
-
40
-
-
33847419281
-
Filamin links cell shape and cytoskeletal structure to Rho regulation by controlling accumulation of p190RhoGAP in lipid rafts
-
DOI 10.1242/jcs.03353
-
Mammoto A, Huang S, Ingber DE. Filamin links cell shape and cytoskeletal structure to Rho regulation by controlling accumulation of p190RhoGAP in lipid rafts. J Cell Sci 2007;120:456-467. (Pubitemid 46332509)
-
(2007)
Journal of Cell Science
, vol.120
, Issue.3
, pp. 456-467
-
-
Mammoto, A.1
Huang, S.2
Ingber, D.E.3
|