-
1
-
-
61849117080
-
The platelet cytoskeleton
-
In: Michelson AD, editor, 2 ed: Academic Press
-
Hartwig JH (2007) The platelet cytoskeleton. In: Michelson AD, editor. Platelets. 2 ed: Academic Press. 75-98.
-
(2007)
Platelets
, pp. 75-98
-
-
Hartwig, J.H.1
-
2
-
-
70449485000
-
Normal filopodia extension in VASP-deficient platelets upon activation by adhesive matrices or soluble agonists
-
Eliautou S, Mangin PH, Walter U, Gachet C, Lanza F, (2009) Normal filopodia extension in VASP-deficient platelets upon activation by adhesive matrices or soluble agonists. Thromb Haemost 102: 792-794.
-
(2009)
Thromb Haemost
, vol.102
, pp. 792-794
-
-
Eliautou, S.1
Mangin, P.H.2
Walter, U.3
Gachet, C.4
Lanza, F.5
-
3
-
-
0032101012
-
RhoA and the function of platelet integrin alphaIIbbeta3
-
Leng L, Kashiwagi H, Ren XD, Shattil SJ, (1998) RhoA and the function of platelet integrin alphaIIbbeta3. Blood 91: 4206-4215.
-
(1998)
Blood
, vol.91
, pp. 4206-4215
-
-
Leng, L.1
Kashiwagi, H.2
Ren, X.D.3
Shattil, S.J.4
-
4
-
-
28244479366
-
Rac1 is essential for platelet lamellipodia formation and aggregate stability under flow
-
McCarty OJ, Larson MK, Auger JM, Kalia N, Atkinson BT, et al. (2005) Rac1 is essential for platelet lamellipodia formation and aggregate stability under flow. J Biol Chem 280: 39474-39484.
-
(2005)
J Biol Chem
, vol.280
, pp. 39474-39484
-
-
McCarty, O.J.1
Larson, M.K.2
Auger, J.M.3
Kalia, N.4
Atkinson, B.T.5
-
5
-
-
30544438322
-
The integrin alpha6beta1 modulation of PI3K and Cdc42 activities induces dynamic filopodium formation in human platelets
-
Chang JC, Chang HH, Lin CT, Lo SJ, (2005) The integrin alpha6beta1 modulation of PI3K and Cdc42 activities induces dynamic filopodium formation in human platelets. J Biomed Sci 12: 881-898.
-
(2005)
J Biomed Sci
, vol.12
, pp. 881-898
-
-
Chang, J.C.1
Chang, H.H.2
Lin, C.T.3
Lo, S.J.4
-
6
-
-
42449153335
-
Critical roles for the actin cytoskeleton and cdc42 in regulating platelet integrin alpha2beta1
-
Pula G, Poole AW, (2008) Critical roles for the actin cytoskeleton and cdc42 in regulating platelet integrin alpha2beta1. Platelets 19: 199-210.
-
(2008)
Platelets
, vol.19
, pp. 199-210
-
-
Pula, G.1
Poole, A.W.2
-
7
-
-
77951459334
-
Multiple alterations of platelet functions dominated by increased secretion in mice lacking Cdc42 in platelets
-
Pleines I, Eckly A, Elvers M, Hagedorn I, Eliautou S, et al. (2010) Multiple alterations of platelet functions dominated by increased secretion in mice lacking Cdc42 in platelets. Blood 115: 3364-3373.
-
(2010)
Blood
, vol.115
, pp. 3364-3373
-
-
Pleines, I.1
Eckly, A.2
Elvers, M.3
Hagedorn, I.4
Eliautou, S.5
-
8
-
-
77649271537
-
The role of formins in filopodia formation
-
Mellor H, (2010) The role of formins in filopodia formation. Biochim Biophys Acta 1803: 191-200.
-
(2010)
Biochim Biophys Acta
, vol.1803
, pp. 191-200
-
-
Mellor, H.1
-
9
-
-
0034597539
-
The novel Rho-family GTPase rif regulates coordinated actin-based membrane rearrangements
-
Ellis S, Mellor H, (2000) The novel Rho-family GTPase rif regulates coordinated actin-based membrane rearrangements. Curr Biol 10: 1387-1390.
-
(2000)
Curr Biol
, vol.10
, pp. 1387-1390
-
-
Ellis, S.1
Mellor, H.2
-
10
-
-
66549084876
-
A HaemAtlas: characterizing gene expression in differentiated human blood cells
-
Watkins NA, Gusnanto A, de Bono B, De S, Miranda-Saavedra D, et al. (2009) A HaemAtlas: characterizing gene expression in differentiated human blood cells. Blood 113: e1-9.
-
(2009)
Blood
, vol.113
-
-
Watkins, N.A.1
Gusnanto, A.2
de Bono, B.3
De, S.4
Miranda-Saavedra, D.5
-
11
-
-
79961071855
-
Genome wide RNA-seq analysis of human and mouse platelet transcriptomes
-
Rowley JW, Oler A, Tolley ND, Hunter B, Low EN, et al. (2011) Genome wide RNA-seq analysis of human and mouse platelet transcriptomes. Blood.
-
(2011)
Blood
-
-
Rowley, J.W.1
Oler, A.2
Tolley, N.D.3
Hunter, B.4
Low, E.N.5
-
12
-
-
0942268723
-
Rho GTPases have diverse effects on the organization of the actin filament system
-
Aspenstrom P, Fransson A, Saras J, (2004) Rho GTPases have diverse effects on the organization of the actin filament system. Biochem J 377: 327-337.
-
(2004)
Biochem J
, vol.377
, pp. 327-337
-
-
Aspenstrom, P.1
Fransson, A.2
Saras, J.3
-
13
-
-
70450222906
-
Rif proteins take to the RhoD: Rho GTPases at the crossroads of actin dynamics and membrane trafficking
-
Gad AK, Aspenstrom P, (2010) Rif proteins take to the RhoD: Rho GTPases at the crossroads of actin dynamics and membrane trafficking. Cell Signal 22: 183-189.
-
(2010)
Cell Signal
, vol.22
, pp. 183-189
-
-
Gad, A.K.1
Aspenstrom, P.2
-
14
-
-
65349085563
-
Defining mechanisms of actin polymerization and depolymerization during dendritic spine morphogenesis
-
Hotulainen P, Llano O, Smirnov S, Tanhuanpaa K, Faix J, et al. (2009) Defining mechanisms of actin polymerization and depolymerization during dendritic spine morphogenesis. J Cell Biol 185: 323-339.
-
(2009)
J Cell Biol
, vol.185
, pp. 323-339
-
-
Hotulainen, P.1
Llano, O.2
Smirnov, S.3
Tanhuanpaa, K.4
Faix, J.5
-
15
-
-
77951191158
-
The small GTPase Rif is an alternative trigger for the formation of actin stress fibers in epithelial cells
-
Fan L, Pellegrin S, Scott A, Mellor H, (2010) The small GTPase Rif is an alternative trigger for the formation of actin stress fibers in epithelial cells. J Cell Sci 123: 1247-1252.
-
(2010)
J Cell Sci
, vol.123
, pp. 1247-1252
-
-
Fan, L.1
Pellegrin, S.2
Scott, A.3
Mellor, H.4
-
16
-
-
79953885132
-
Rif-mDia1 interaction is involved in filopodium formation independent of Cdc42 and Rac effectors
-
Goh WI, Sudhaharan T, Lim KB, Sem KP, Lau CL, et al. (2011) Rif-mDia1 interaction is involved in filopodium formation independent of Cdc42 and Rac effectors. J Biol Chem 286: 13681-13694.
-
(2011)
J Biol Chem
, vol.286
, pp. 13681-13694
-
-
Goh, W.I.1
Sudhaharan, T.2
Lim, K.B.3
Sem, K.P.4
Lau, C.L.5
-
17
-
-
12544253725
-
The Rho family GTPase Rif induces filopodia through mDia2
-
Pellegrin S, Mellor H, (2005) The Rho family GTPase Rif induces filopodia through mDia2. Curr Biol 15: 129-133.
-
(2005)
Curr Biol
, vol.15
, pp. 129-133
-
-
Pellegrin, S.1
Mellor, H.2
-
18
-
-
19544386803
-
Structural and mechanistic insights into the interaction between Rho and mammalian Dia
-
Rose R, Weyand M, Lammers M, Ishizaki T, Ahmadian MR, et al. (2005) Structural and mechanistic insights into the interaction between Rho and mammalian Dia. Nature 435: 513-518.
-
(2005)
Nature
, vol.435
, pp. 513-518
-
-
Rose, R.1
Weyand, M.2
Lammers, M.3
Ishizaki, T.4
Ahmadian, M.R.5
-
19
-
-
43749120730
-
Biochemical characterization of the Rho GTPase-regulated actin assembly by diaphanous-related formins, mDia1 and Daam1, in platelets
-
Higashi T, Ikeda T, Shirakawa R, Kondo H, Kawato M, et al. (2008) Biochemical characterization of the Rho GTPase-regulated actin assembly by diaphanous-related formins, mDia1 and Daam1, in platelets. J Biol Chem 283: 8746-8755.
-
(2008)
J Biol Chem
, vol.283
, pp. 8746-8755
-
-
Higashi, T.1
Ikeda, T.2
Shirakawa, R.3
Kondo, H.4
Kawato, M.5
-
20
-
-
61749097572
-
PKCalpha regulates platelet granule secretion and thrombus formation in mice
-
Konopatskaya O, Gilio K, Harper MT, Zhao Y, Cosemans JM, et al. (2009) PKCalpha regulates platelet granule secretion and thrombus formation in mice. J Clin Invest 119: 399-407.
-
(2009)
J Clin Invest
, vol.119
, pp. 399-407
-
-
Konopatskaya, O.1
Gilio, K.2
Harper, M.T.3
Zhao, Y.4
Cosemans, J.M.5
-
21
-
-
77949308494
-
RGD-ligand mimetic antagonists of integrin alphaIIbbeta3 paradoxically enhance GPVI-induced human platelet activation
-
Jones ML, Harper MT, Aitken EW, Williams CM, Poole AW, (2010) RGD-ligand mimetic antagonists of integrin alphaIIbbeta3 paradoxically enhance GPVI-induced human platelet activation. J Thromb Haemost 8: 567-576.
-
(2010)
J Thromb Haemost
, vol.8
, pp. 567-576
-
-
Jones, M.L.1
Harper, M.T.2
Aitken, E.W.3
Williams, C.M.4
Poole, A.W.5
-
22
-
-
77954945985
-
Functional divergence of platelet protein kinase C (PKC) isoforms in thrombus formation on collagen
-
Gilio K, Harper MT, Cosemans JM, Konopatskaya O, Munnix IC, et al. (2010) Functional divergence of platelet protein kinase C (PKC) isoforms in thrombus formation on collagen. J Biol Chem 285: 23410-23419.
-
(2010)
J Biol Chem
, vol.285
, pp. 23410-23419
-
-
Gilio, K.1
Harper, M.T.2
Cosemans, J.M.3
Konopatskaya, O.4
Munnix, I.C.5
-
23
-
-
84863011162
-
Megakaryocyte-specific RhoA deficiency causes macrothrombocytopenia and defective platelet activation in hemostasis and thrombosis
-
Pleines I, Hagedorn I, Gupta S, May F, Chakarova L, et al. (2012) Megakaryocyte-specific RhoA deficiency causes macrothrombocytopenia and defective platelet activation in hemostasis and thrombosis. Blood 119: 1054-1063.
-
(2012)
Blood
, vol.119
, pp. 1054-1063
-
-
Pleines, I.1
Hagedorn, I.2
Gupta, S.3
May, F.4
Chakarova, L.5
-
24
-
-
50149083752
-
Mammalian Rho GTPases: new insights into their functions from in vivo studies
-
Heasman SJ, Ridley AJ, (2008) Mammalian Rho GTPases: new insights into their functions from in vivo studies. Nat Rev Mol Cell Biol 9: 690-701.
-
(2008)
Nat Rev Mol Cell Biol
, vol.9
, pp. 690-701
-
-
Heasman, S.J.1
Ridley, A.J.2
-
25
-
-
79960567744
-
Gene targeting implicates Cdc42 GTPase in GPVI and non-GPVI mediated platelet filopodia formation, secretion and aggregation
-
Akbar H, Shang X, Perveen R, Berryman M, Funk K, et al. (2011) Gene targeting implicates Cdc42 GTPase in GPVI and non-GPVI mediated platelet filopodia formation, secretion and aggregation. PLoS One 6: e22117.
-
(2011)
PLoS One
, vol.6
-
-
Akbar, H.1
Shang, X.2
Perveen, R.3
Berryman, M.4
Funk, K.5
-
26
-
-
0037382160
-
Disruption of the Diaphanous-related formin Drf1 gene encoding mDia1 reveals a role for Drf3 as an effector for Cdc42
-
Peng J, Wallar BJ, Flanders A, Swiatek PJ, Alberts AS, (2003) Disruption of the Diaphanous-related formin Drf1 gene encoding mDia1 reveals a role for Drf3 as an effector for Cdc42. Curr Biol 13: 534-545.
-
(2003)
Curr Biol
, vol.13
, pp. 534-545
-
-
Peng, J.1
Wallar, B.J.2
Flanders, A.3
Swiatek, P.J.4
Alberts, A.S.5
-
28
-
-
80051599187
-
G-protein coupled and ITAM receptor regulation of the formin FHOD1 through Rho kinase in platelets
-
Thomas SG, Calaminus SD, Machesky LM, Alberts AS, Watson SP, (2011) G-protein coupled and ITAM receptor regulation of the formin FHOD1 through Rho kinase in platelets. J Thromb Haemost 9: 1648-1651.
-
(2011)
J Thromb Haemost
, vol.9
, pp. 1648-1651
-
-
Thomas, S.G.1
Calaminus, S.D.2
Machesky, L.M.3
Alberts, A.S.4
Watson, S.P.5
-
29
-
-
84856945929
-
mDia1 and WAVE2 proteins interact directly with IRSp53 in filopodia and are involved in filopodium formation
-
Goh WI, Lim KB, Sudhaharan T, Sem KP, Bu W, et al. (2012) mDia1 and WAVE2 proteins interact directly with IRSp53 in filopodia and are involved in filopodium formation. J Biol Chem 287: 4702-4714.
-
(2012)
J Biol Chem
, vol.287
, pp. 4702-4714
-
-
Goh, W.I.1
Lim, K.B.2
Sudhaharan, T.3
Sem, K.P.4
Bu, W.5
-
30
-
-
33645240619
-
Secramine inhibits Cdc42-dependent functions in cells and Cdc42 activation in vitro
-
Pelish HE, Peterson JR, Salvarezza SB, Rodriguez-Boulan E, Chen JL, et al. (2006) Secramine inhibits Cdc42-dependent functions in cells and Cdc42 activation in vitro. Nat Chem Biol 2: 39-46.
-
(2006)
Nat Chem Biol
, vol.2
, pp. 39-46
-
-
Pelish, H.E.1
Peterson, J.R.2
Salvarezza, S.B.3
Rodriguez-Boulan, E.4
Chen, J.L.5
-
31
-
-
33845512493
-
PKCdelta regulates collagen-induced platelet aggregation through inhibition of VASP-mediated filopodia formation
-
Pula G, Schuh K, Nakayama K, Nakayama KI, Walter U, et al. (2006) PKCdelta regulates collagen-induced platelet aggregation through inhibition of VASP-mediated filopodia formation. Blood 108: 4035-4044.
-
(2006)
Blood
, vol.108
, pp. 4035-4044
-
-
Pula, G.1
Schuh, K.2
Nakayama, K.3
Nakayama, K.I.4
Walter, U.5
|