The N-terminal DH-PH domain of trio induces cell spreading and migration by regulating lamellipodia dynamics in a Rac1-dependent fashion

PLoS ONE

Volumn 7, Issue 1, 2012, Pages

  van Rijssel, Jos ^a   Hoogenboezem, Mark ^a   Wester, Lynn ^a   Hordijk, Peter L ^a   van Buul, Jaap D ^a  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

FIBRONECTIN; PROLINE; RAC1 PROTEIN; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; SHORT HAIRPIN RNA; GUANINE NUCLEOTIDE EXCHANGE FACTOR; PROTEIN SERINE THREONINE KINASE; RAC1 PROTEIN, HUMAN; SMALL INTERFERING RNA; TRIO PROTEIN, HUMAN;

AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL DAMAGE; CELL MIGRATION; CELL SPREADING; HELA CELL; HUMAN; HUMAN CELL; LAMELLIPODIUM; MOLECULAR DYNAMICS; PROTEIN BINDING; PROTEIN DEFICIENCY; PROTEIN DOMAIN; PROTEIN EXPRESSION; CELL ADHESION; CELL MOTION; CHEMISTRY; DRUG ANTAGONISM; DRUG EFFECT; FLUORESCENCE MICROSCOPY; GENE EXPRESSION REGULATION; GENETICS; KINETICS; METABOLISM; PHYSIOLOGY; PSEUDOPODIUM; SCANNING ELECTRON MICROSCOPY;

CELL ADHESION; CELL MOVEMENT; FIBRONECTINS; GENE EXPRESSION REGULATION, NEOPLASTIC; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HELA CELLS; HUMANS; KINETICS; MICROSCOPY, ELECTRON, SCANNING; MICROSCOPY, FLUORESCENCE; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN-SERINE-THREONINE KINASES; PSEUDOPODIA; RAC1 GTP-BINDING PROTEIN; RNA, SMALL INTERFERING;

EID: 84855468015     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0029912     Document Type: Article

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