Modeling of G protein-coupled receptors using crystal structures: From monomers to signaling complexes

Advances in Experimental Medicine and Biology

Volumn 796, Issue , 2014, Pages 15-33

  Gonzalez, Angel ^a   Cordomí, Arnau ^a   Matsoukas, Minos ^a   Zachmann, Julian ^a   Pardo, Leonardo ^a  

^a UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

Author keywords

Activation mechanism; Conformation; Homology modeling; Ligand binding; Transmembrane helices

Indexed keywords

G PROTEIN COUPLED RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; RETINA S ANTIGEN; ADENOSINE A2 RECEPTOR; BETA 1 ADRENERGIC RECEPTOR; BETA 2 ADRENERGIC RECEPTOR; CHEMOKINE RECEPTOR CXCR4; DELTA OPIATE RECEPTOR; DOPAMINE 3 RECEPTOR; HISTAMINE H1 RECEPTOR; KAPPA OPIATE RECEPTOR; MU OPIATE RECEPTOR; MUSCARINIC M2 RECEPTOR; MUSCARINIC M3 RECEPTOR; NEUROTENSIN; OPSIN; PROTEINASE ACTIVATED RECEPTOR 1; RHO FACTOR; RHODOPSIN; SEROTONIN 1B RECEPTOR; SMOOTHENED PROTEIN; SPHINGOSINE KINASE 1;

ALPHA HELIX; AMINO TERMINAL SEQUENCE; ARTICLE; BETA SHEET; BINDING SITE; CARBOXY TERMINAL SEQUENCE; COMPLEX FORMATION; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; LIGAND BINDING; MOLECULAR MODEL; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN FOLDING; PROTEIN PROTEIN INTERACTION; SEQUENCE HOMOLOGY; SIGNAL TRANSDUCTION; STRUCTURE ANALYSIS; CONFORMATION; EXTRACELLULAR MATRIX; HUMAN; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN MOTIF; PROTEIN STRUCTURE; PROTEIN TARGETING; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS; TRANSMEMBRANE HELIX 2; TRANSMEMBRANE HELIX 3; TRANSMEMBRANE HELIX 4; TRANSMEMBRANE HELIX 5; TRANSMEMBRANE HELIX 6; TRANSMEMBRANE HELIX 7;

EID: 84934439403     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-94-7-7423-0_2     Document Type: Article

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