Non-α-helical elements modulate polytopic membrane protein architecture

Journal of Molecular Biology

Volumn 306, Issue 2, 2001, Pages 349-362

  Riek, R Peter ^a   Rigoutsos, Isidore ^d   Novotny, Jiri ^a,c   Graham, Robert M ^a,b  

^a ST VINCENT S HOSPITAL   (Australia)

^b UNIVERSITY OF NEW SOUTH WALES   (Australia)

^c PRINCETON UNIVERSITY   (United States)

^d IBM T J WATSON RESEARCH CENTER   (United States)

Author keywords

Helical fine structure; Kink; Proline; Transmembrane helices; bulge

Indexed keywords

BACTERIORHODOPSIN; G PROTEIN COUPLED RECEPTOR; ION CHANNEL; MEMBRANE PROTEIN; RHODOPSIN;

ALPHA HELIX; ARTICLE; MACROMOLECULE; MOLECULAR MODEL; PHOTOSYNTHESIS; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN STRUCTURE;

EID: 0035895421     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.2000.4402     Document Type: Article

References (50)

1. The packing of α-helices: Simple coiled coils
2. Helix-to-helix packing in proteins
3. Sequence specificity in dimerization of transmembrane α-helices
4. The effect of point mutations on the free energy of transmembrane α-helix dimerization
5. Helix packing in membrane proteins
6. Asparagine-mediated self-association of a model transmembrane helix
7. Interhelical hydrogen bonding drives strong interactions in membrane proteins
8. The GxxxG motif: A framework for transmembrane helix-helix association
9. Statistical analysis of amino acid patterns in transmembrane helices: The GxxxG motif occurs frequently and in association with β-branched residues at neighboring positions
10. Helix geometry in proteins
11. Influence of proline residues on protein conformation
12. Conformational parameters for amino acids in helical, beta sheet, and random coil regions calculated from proteins
13. Prediction of protein conformation
14. Proline kinks in transmembrane α-helices
15. The structure of proteins: Two hydrogen-bonded helical configurations of the polypeptide chain
16. Solvent-induced distortions and the curvature of α-helices
17. 10-helix
18. A unique or essentially unique single parametric characterization of biopolymeric structures
19. Use of helical wheels to represent the structures of proteins and to identify segments with helical potential
20. The Protein Data Bank
21. The Protein Data Bank: A computer-based archival file for macromolecular structures
22. Crystal structure of rhodopsin: A G protein-coupled receptor
23. Redox-coupled crystal structural changes in bovine heart cytochrome c oxidase
24. Structure at 2.7 Å resolution of the Paracoccus denitrificans two-subunit cytochrome c oxidase complexed with an antibody FV fragment
25. Structure of the E. coli fumarate reductase respiratory complex
26. Complete structure of the 11-subunit bovine mitochondrial cytochrome bc1 complex
27. Crystallographic refinement at 2.3 Å resolution and refined model of the photosynthetic reaction centre from Rhodopseudomonas viridis
28. Light-induced structural changes in photosynthetic reaction center: Implications for mechanism of electron-proton transfer
29. Structure of bacteriorhodopsin at 1.55 angstrom resolution
30. Structural changes in bacteriorhodopsin during ion transport at 2 Å resolution
31. Structure of light-driven chloride pump halorhodopsin at 1.8 Å resolution
32. Crystal structure of the calcium pump of sarcoplasmic reticulum at 2.6 Å resolution
33. The α aneurism: A structural motif revealed in an insertion mutant of staphylococcal nuclease
34. C-H···O hydrogen bonding in biology
35. Combinatorial pattern discovery in biological sequences: The TEIRESIAS algorithm
36. A novel group of very long chain polyenoic fatty acids in dipolyunsaturated phosphatidylcholines from vertebrate retina
37. Very long chain (C24 to C36) polyenoic fatty acids of the n-3 and n-6 series in dipolyunsaturated phosphatidylcholines from bovine retina
38. 1b-adrenergic receptor is a key switch residue involved in activation and catecholamine ring aromatic bonding
39. 1b-adrenergic receptor signal-inactivating point mutation
40. Requirement of a rigid-body motion of transmembrane helices for light activation of rhodopsin
41. The ninaA gene required for visual transduction in Drosophila encodes a homologue cyclosporin A-binding protein
42. Evolutionary conservation of both the hydrophilic and hydrophobic nature of transmembrane helices
43. An α-carbon template for the transmembrane helices in the rhodopsin family of the G protein-coupled receptors
44. An alpha-carbon template for the transmembrane helices in the rhodopsin family of G-protein-coupled receptors
45. Biased probability Monte Carlo conformational searches and electrostatic calculations for peptides and proteins
46. ICM-a new method for protein modeling and design. Applications to docking and structure prediction from the distorted native conformation
47. Design of heterotetrameric coiled-coils: Evidence for increased stabilization by Glu-Lys ion pair interactions
48. Factors influencing accuracy of computer-built models: A study based on leucine zipper GCN4 structure