-
1
-
-
0035805229
-
Recognition of cognate transfer RNA by the 30S ribosomal subunit
-
Ogle, J.M., Brodersen, D.E., Clemons, W.M. Jr., Tarry, M.J., Carter, A.P., and Ramakrishnan, V. (2001) Recognition of cognate transfer RNA by the 30S ribosomal subunit. Science, 292, 897-902.
-
(2001)
Science
, vol.292
, pp. 897-902
-
-
Ogle, J.M.1
Brodersen, D.E.2
Clemons, W.M.3
Tarry, M.J.4
Carter, A.P.5
Ramakrishnan, V.6
-
2
-
-
0038403669
-
Insights into the decoding mechanism from recent ribosome structures
-
Ogle, J.M., Carter, A.P., and Ramakrishnan, V. (2003) Insights into the decoding mechanism from recent ribosome structures. Trends Biochem. Sci., 28, 259-266.
-
(2003)
Trends Biochem. Sci
, vol.28
, pp. 259-266
-
-
Ogle, J.M.1
Carter, A.P.2
Ramakrishnan, V.3
-
3
-
-
0037184536
-
Selection of tRNA by the ribosome requires a transition from an open to a closed form
-
Ogle, J.M., Murphy, F.V., Tarry, M.J., and Ramakrishnan, V. (2002) Selection of tRNA by the ribosome requires a transition from an open to a closed form. Cell, 111, 721-732.
-
(2002)
Cell
, vol.111
, pp. 721-732
-
-
Ogle, J.M.1
Murphy, F.V.2
Tarry, M.J.3
Ramakrishnan, V.4
-
4
-
-
18844413446
-
Structural insights into translational fidelity
-
Ogle, J.M. and Ramakrishnan, V. (2005) Structural insights into translational fidelity. Annu. Rev. Biochem., 74, 129-177.
-
(2005)
Annu. Rev. Biochem
, vol.74
, pp. 129-177
-
-
Ogle, J.M.1
Ramakrishnan, V.2
-
5
-
-
43349099033
-
-
(ed D.P. Arya), Wiley-Interscience, Hoboken, NJ
-
Kondo, J. and Westhof, E. (2007) in Aminoglycoside Antibiotics from Chemical Biology to Drug Discovery (ed D.P. Arya), Wiley-Interscience, Hoboken, NJ, pp. 209-223.
-
(2007)
Aminoglycoside Antibiotics from Chemical Biology to Drug Discovery
, pp. 209-223
-
-
Kondo, J.1
Westhof, E.2
-
6
-
-
28844501658
-
Analysis of the contribution of individual substituents in 4,6-aminoglycosideribosome interaction
-
Hobbie, S.N., Pfister, P., Brüll, C., Westhof, E., and Böttger, E.C. (2005) Analysis of the contribution of individual substituents in 4,6-aminoglycosideribosome interaction. Antimicrob. Agents Chemother., 49, 5112-5118.
-
(2005)
Antimicrob. Agents Chemother
, vol.49
, pp. 5112-5118
-
-
Hobbie, S.N.1
Pfister, P.2
Brüll, C.3
Westhof, E.4
Böttger, E.C.5
-
7
-
-
33645757767
-
Binding of neomycin-class aminoglycoside antibiotics to mutant ribosomes with alterations in the A site of 16S rRNA
-
Hobbie, S.N., Pfister, P., Bruell, C., Sander, P., François, B., Westhof, E., and Böttger, E.C. (2006) Binding of neomycin-class aminoglycoside antibiotics to mutant ribosomes with alterations in the A site of 16S rRNA. Antimicrob. Agents Chemother., 50, 1489-1496.
-
(2006)
Antimicrob. Agents Chemother
, vol.50
, pp. 1489-1496
-
-
Hobbie, S.N.1
Pfister, P.2
Bruell, C.3
Sander, P.4
François, B.5
Westhof, E.6
Böttger, E.C.7
-
8
-
-
0033152492
-
Basis for prokaryotic specificity of action of aminoglycoside antibiotics
-
Recht, M.I., Douthwaite, S., and Puglisi, J.D. (1999) Basis for prokaryotic specificity of action of aminoglycoside antibiotics. EMBO J., 18, 3133-3138.
-
(1999)
EMBO J
, vol.18
, pp. 3133-3138
-
-
Recht, M.I.1
Douthwaite, S.2
Puglisi, J.D.3
-
9
-
-
58549117857
-
Genetic analysis of interactions with eukaryotic rRNA identify the mitoribosome as target in aminoglycoside ototoxicity
-
Hobbie, S.N., Akshay, S., Kalapala, S.K., Bruell, C.M., Shcherbakov, D., and Böttger, E.C. (2008) Genetic analysis of interactions with eukaryotic rRNA identify the mitoribosome as target in aminoglycoside ototoxicity. Proc. Natl. Acad. Sci. U.S.A., 105, 20888-20893.
-
(2008)
Proc. Natl. Acad. Sci. U.S. A
, vol.105
, pp. 20888-20893
-
-
Hobbie, S.N.1
Akshay, S.2
Kalapala, S.K.3
Bruell, C.M.4
Shcherbakov, D.5
Böttger, E.C.6
-
10
-
-
35548944012
-
Engineering the rRNA decoding site of eukaryotic cytosolic ribosomes in bacteria
-
Hobbie, S.N., Kalapala, S.K., Akshay, S., Bruell, C., Schmidt, S., Dabow, S., Vasella, A., Sander, P., and Böttger, E.C. (2007) Engineering the rRNA decoding site of eukaryotic cytosolic ribosomes in bacteria. Nucleic Acids Res., 35, 6086-6093.
-
(2007)
Nucleic Acids Res
, vol.35
, pp. 6086-6093
-
-
Hobbie, S.N.1
Kalapala, S.K.2
Akshay, S.3
Bruell, C.4
Schmidt, S.5
Dabow, S.6
Vasella, A.7
Sander, P.8
Böttger, E.C.9
-
11
-
-
0033621114
-
Determinants of aminoglycoside-binding specificity for rRNA by using mass spectrometry
-
Griffey, R.H., Hofstadler, S.A., Sannes-Lowery, K.A., Ecker, D.J., and Crooke, S.T. (1999) Determinants of aminoglycoside-binding specificity for rRNA by using mass spectrometry. Proc. Natl. Acad. Sci. U.S.A., 96, 10129-10133.
-
(1999)
Proc. Natl. Acad. Sci. U.S. A
, vol.96
, pp. 10129-10133
-
-
Griffey, R.H.1
Hofstadler, S.A.2
Sannes-Lowery, K.A.3
Ecker, D.J.4
Crooke, S.T.5
-
12
-
-
33750689865
-
Redesign of aminoglycosides for treatment of human genetic diseases caused by premature stop mutations
-
Nudelman, I., Rebibo-Sabbah, A., Shallom-Shezifi, D., Hainrichson, M., Stahl, I., Ben-Yosef, T., and Baasov, T. (2006) Redesign of aminoglycosides for treatment of human genetic diseases caused by premature stop mutations. Bioorg. Med. Chem. Lett., 16, 6310-6315.
-
(2006)
Bioorg. Med. Chem. Lett
, vol.16
, pp. 6310-6315
-
-
Nudelman, I.1
Rebibo-Sabbah, A.2
Shallom-Shezifi, D.3
Hainrichson, M.4
Stahl, I.5
Ben-Yosef, T.6
Baasov, T.7
-
13
-
-
0034699519
-
Functional insights from the structure of the 30S ribosomal subunit and its interactions with antibiotics
-
Carter, A.P., Clemons, W.M., Brodersen, D.E., Morgan-Warren, R.J., Wimberly, B.T., and Ramakrishnan, V. (2000) Functional insights from the structure of the 30S ribosomal subunit and its interactions with antibiotics. Nature, 407, 340-348.
-
(2000)
Nature
, vol.407
, pp. 340-348
-
-
Carter, A.P.1
Clemons, W.M.2
Brodersen, D.E.3
Morgan-Warren, R.J.4
Wimberly, B.T.5
Ramakrishnan, V.6
-
14
-
-
0034886697
-
Crystal structure of paromomycin docked into the eubacterial ribosomal decoding A site
-
Vicens, Q. and Westhof, E. (2001) Crystal structure of paromomycin docked into the eubacterial ribosomal decoding A site. Structure, 9, 647-658.
-
(2001)
Structure
, vol.9
, pp. 647-658
-
-
Vicens, Q.1
Westhof, E.2
-
15
-
-
0035986708
-
Crystal structure of a complex between the aminoglycoside tobramycin and an oligonucleotide containing the ribosomal decoding A site
-
Vicens, Q. and Westhof, E. (2002) Crystal structure of a complex between the aminoglycoside tobramycin and an oligonucleotide containing the ribosomal decoding A site. Chem. Biol., 9, 747-755.
-
(2002)
Chem. Biol
, vol.9
, pp. 747-755
-
-
Vicens, Q.1
Westhof, E.2
-
16
-
-
0037470560
-
Crystal structure of geneticin bound to a bacterial 16S ribosomal RNA A site oligonucleotide
-
Vicens, Q. and Westhof, E. (2003) Crystal structure of geneticin bound to a bacterial 16S ribosomal RNA A site oligonucleotide. J. Mol. Biol., 326, 1175-1188.
-
(2003)
J. Mol. Biol
, vol.326
, pp. 1175-1188
-
-
Vicens, Q.1
Westhof, E.2
-
17
-
-
10944252964
-
Antibacterial aminoglycosides with a modified mode of binding to the ribosomal-RNA decoding site
-
François, B., Szychowski, J., Adhikari, S.S., Pachamuthu, K., Swayze, E.E., Griffey, R.H., Migawa, M.T., Westhof, E., and Hanessian, S. (2004) Antibacterial aminoglycosides with a modified mode of binding to the ribosomal-RNA decoding site. Angew. Chem. Int. Ed., 43, 6735-6738.
-
(2004)
Angew. Chem. Int. Ed
, vol.43
, pp. 6735-6738
-
-
François, B.1
Szychowski, J.2
Adhikari, S.S.3
Pachamuthu, K.4
Swayze, E.E.5
Griffey, R.H.6
Migawa, M.T.7
Westhof, E.8
Hanessian, S.9
-
18
-
-
27244458194
-
Crystal structures of complexes between aminoglycosides and decoding A site oligonucleotides: Role of the number of rings and positive charges in the specific binding leading to miscoding
-
François, B., Russell, R.J.M., Murray, J.B., Aboul-ela, F., Masquida, B., Vicens, Q., and Westhof, E. (2005) Crystal structures of complexes between aminoglycosides and decoding A site oligonucleotides: role of the number of rings and positive charges in the specific binding leading to miscoding. Nucleic Acids Res., 33, 5677-5690.
-
(2005)
Nucleic Acids Res
, vol.33
, pp. 5677-5690
-
-
François, B.1
Russell, R.J.M.2
Murray, J.B.3
Aboul-ela, F.4
Masquida, B.5
Vicens, Q.6
Westhof, E.7
-
19
-
-
33747872896
-
Crystal structure of the bacterial ribosomal decoding site complexed with amikacin containing the γ-amino-α-hydroxybutyryl (haba) group
-
Kondo, J., François, B., Russell, R.J., Murray, J.B., and Westhof, E. (2006) Crystal structure of the bacterial ribosomal decoding site complexed with amikacin containing the γ-amino-α-hydroxybutyryl (haba) group. Biochimie, 88, 1027-1031.
-
(2006)
Biochimie
, vol.88
, pp. 1027-1031
-
-
Kondo, J.1
François, B.2
Russell, R.J.3
Murray, J.B.4
Westhof, E.5
-
20
-
-
34249094161
-
2 ether analogues of paromomycin
-
2 ether analogues of paromomycin. J. Med. Chem., 50, 2352-2369.
-
(2007)
J. Med. Chem
, vol.50
, pp. 2352-2369
-
-
Hanessian, S.1
Szychowski, J.2
Adhikari, S.S.3
Vasquez, G.4
Kandasamy, P.5
Swayze, E.E.6
Migawa, M.T.7
Ranken, R.8
François, B.9
Wirmer-Bartoschek, J.10
Kondo, J.11
Westhof, E.12
-
21
-
-
49649109590
-
Crystal structure of the bacterial ribosomal decoding site complexed with a synthetic doubly functionalized paromomycin derivative: A new specific binding mode to an a-minor motif enhances in vitro antibacterial activity
-
Kondo, J., Pachamuthu, K., François, B., Szychowski, J., Hanessian, S., and Westhof, E. (2007) Crystal structure of the bacterial ribosomal decoding site complexed with a synthetic doubly functionalized paromomycin derivative: a new specific binding mode to an a-minor motif enhances in vitro antibacterial activity. ChemMedChem, 2, 1631-1638.
-
(2007)
ChemMedChem
, vol.2
, pp. 1631-1638
-
-
Kondo, J.1
Pachamuthu, K.2
François, B.3
Szychowski, J.4
Hanessian, S.5
Westhof, E.6
-
22
-
-
78149282652
-
Structurebased design, synthesis and A-site rRNA co-crystal complexes of novel amphiphilic aminoglycoside antibiotics with new binding modes: A synergistic hydrophobic effect against resistant bacteria
-
Hanessian, S., Pachamuthu, K., Szychowski, J., Giguère, A., Swayze, E.E., Migawa, M.T., François, B., Kondo, J., and Westhof, E. (2010) Structurebased design, synthesis and A-site rRNA co-crystal complexes of novel amphiphilic aminoglycoside antibiotics with new binding modes: a synergistic hydrophobic effect against resistant bacteria. Bioorg. Med. Chem. Lett., 20, 7097-7101.
-
(2010)
Bioorg. Med. Chem. Lett
, vol.20
, pp. 7097-7101
-
-
Hanessian, S.1
Pachamuthu, K.2
Szychowski, J.3
Giguère, A.4
Swayze, E.E.5
Migawa, M.T.6
François, B.7
Kondo, J.8
Westhof, E.9
-
23
-
-
80055063276
-
2 ether analogues
-
2-ether analogues. ChemMedChem, 6, 1961-1966.
-
(2011)
ChemMedChem
, vol.6
, pp. 1961-1966
-
-
Szychowski, J.1
Kondo, J.2
Zahr, O.3
Auclair, K.4
Westhof, E.5
Hanessian, S.6
Keillor, J.W.7
-
24
-
-
18844413838
-
Molecular recognition by glycoside pseudo base pairs and triples in an apramycin-RNA complex
-
Han, Q., Zhao, Q., Fish, S., Simonsen, K.B., Vourloumis, D., Froelich, J.M., Wall, D., and Hermann, T. (2005) Molecular recognition by glycoside pseudo base pairs and triples in an apramycin-RNA complex. Angew. Chem. Int. Ed., 44, 2694-2700.
-
(2005)
Angew. Chem. Int. Ed
, vol.44
, pp. 2694-2700
-
-
Han, Q.1
Zhao, Q.2
Fish, S.3
Simonsen, K.B.4
Vourloumis, D.5
Froelich, J.M.6
Wall, D.7
Hermann, T.8
-
25
-
-
24044489584
-
Molecular recognition of RNA by neomycin and a restricted neomycin derivative
-
Zhao, F., Zhao, Q., Blount, K.F., Han, Q., Tor, Y., and Hermann, T. (2005) Molecular recognition of RNA by neomycin and a restricted neomycin derivative. Angew Chem. Int. Ed., 44, 5329-5334.
-
(2005)
Angew Chem. Int. Ed
, vol.44
, pp. 5329-5334
-
-
Zhao, F.1
Zhao, Q.2
Blount, K.F.3
Han, Q.4
Tor, Y.5
Hermann, T.6
-
26
-
-
33747894350
-
A-site model RNAs
-
Hermann, T. (2006) A-site model RNAs. Biochimie, 88, 1021-1026.
-
(2006)
Biochimie
, vol.88
, pp. 1021-1026
-
-
Hermann, T.1
-
27
-
-
77955242816
-
A model for the study of ligand binding to the ribosomal RNA helix h44
-
Dibrov, S.M., Parsons, J., and Hermann, T. (2010) A model for the study of ligand binding to the ribosomal RNA helix h44. Nucleic Acids Res., 38, 4458-4465.
-
(2010)
Nucleic Acids Res
, vol.38
, pp. 4458-4465
-
-
Dibrov, S.M.1
Parsons, J.2
Hermann, T.3
-
28
-
-
0033961143
-
Conformational switch in the decoding region of 16S rRNA during aminoacyl-tRNA selection on the ribosome
-
Pape, T., Wintermeyer, W., and Rodnina, M.V. (2000) Conformational switch in the decoding region of 16S rRNA during aminoacyl-tRNA selection on the ribosome. Nat. Struct. Biol., 7, 104-107.
-
(2000)
Nat. Struct. Biol
, vol.7
, pp. 104-107
-
-
Pape, T.1
Wintermeyer, W.2
Rodnina, M.V.3
-
29
-
-
84859593945
-
A new understanding of the decoding principle on ribosome
-
Demeshkina, N., Jenner, L., Westhof, E., Yusupov, M., and Yusupova, G. (2012) A new understanding of the decoding principle on ribosome. Nature, 484, 256-259.
-
(2012)
Nature
, vol.484
, pp. 256-259
-
-
Demeshkina, N.1
Jenner, L.2
Westhof, E.3
Yusupov, M.4
Yusupova, G.5
-
30
-
-
84855467966
-
A structural basis for the antibiotic resistance conferred by an A1408G mutation in 16S rRNA and for the antiprotozoal activity of aminoglycosides
-
Kondo, J. (2012) A structural basis for the antibiotic resistance conferred by an A1408G mutation in 16S rRNA and for the antiprotozoal activity of aminoglycosides. Angew. Chem. Int. Ed., 51, 465-468.
-
(2012)
Angew. Chem. Int. Ed
, vol.51
, pp. 465-468
-
-
Kondo, J.1
-
31
-
-
32644439242
-
Two conformational states in the crystal structure of the Homo sapiens cytoplasmic ribosomal decoding A site
-
Kondo, J., Urzhumtsev, A., and Westhof, E. (2006) Two conformational states in the crystal structure of the Homo sapiens cytoplasmic ribosomal decoding A site. Nucleic Acids Res., 34, 676-685.
-
(2006)
Nucleic Acids Res
, vol.34
, pp. 676-685
-
-
Kondo, J.1
Urzhumtsev, A.2
Westhof, E.3
-
32
-
-
33746256410
-
Crystal structure of the Homo sapiens cytoplasmic ribosomal decoding site complexed with apramycin
-
Kondo, J., François, B., Urzhumtsev, A., and Westhof, E. (2006) Crystal structure of the Homo sapiens cytoplasmic ribosomal decoding site complexed with apramycin. Angew. Chem. Int. Ed., 45, 3310-3314.
-
(2006)
Angew. Chem. Int. Ed
, vol.45
, pp. 3310-3314
-
-
Kondo, J.1
François, B.2
Urzhumtsev, A.3
Westhof, E.4
-
33
-
-
34948883252
-
Differential selectivity of natural and synthetic aminoglycosides towards the eukaryotic and prokaryotic decoding A sites
-
Kondo, J., Hainrichson, M., Nudelman, I., Shallom-Shezifi, D., Barbieri, C.M., Pilch, D.S., Westhof, E., and Baasov, T. (2007) Differential selectivity of natural and synthetic aminoglycosides towards the eukaryotic and prokaryotic decoding A sites. ChemBioChem, 8, 1700-1709.
-
(2007)
ChemBioChem
, vol.8
, pp. 1700-1709
-
-
Kondo, J.1
Hainrichson, M.2
Nudelman, I.3
Shallom-Shezifi, D.4
Barbieri, C.M.5
Pilch, D.S.6
Westhof, E.7
Baasov, T.8
-
34
-
-
34047110889
-
Apramycin recognition by the human ribosomal decoding site
-
Hermann, T., Tereshko, V., Skripkin, E., and Patel, D.J. (2007) Apramycin recognition by the human ribosomal decoding site. Blood Cells Mol. Dis., 38, 193-198.
-
(2007)
Blood Cells Mol. Dis
, vol.38
, pp. 193-198
-
-
Hermann, T.1
Tereshko, V.2
Skripkin, E.3
Patel, D.J.4
-
35
-
-
43349106027
-
The bacterial and mitochondrial ribosomal Asite molecular switches possess different conformational substrates
-
Kondo, J. and Westhof, E. (2008) The bacterial and mitochondrial ribosomal Asite molecular switches possess different conformational substrates. Nucleic Acids Res., 36, 2654-2666.
-
(2008)
Nucleic Acids Res
, vol.36
, pp. 2654-2666
-
-
Kondo, J.1
Westhof, E.2
-
36
-
-
0036237703
-
Fitness cost of chromosomal drug resistance-conferring mutations
-
Sander, P., Springer, B., Prammananan, T., Sturmfels, A., Kappler, M., Pletschette, M., and Böttger, E.C. (2002) Fitness cost of chromosomal drug resistance-conferring mutations. Antimicrob. Agents Chemother., 46, 1204-1211.
-
(2002)
Antimicrob. Agents Chemother
, vol.46
, pp. 1204-1211
-
-
Sander, P.1
Springer, B.2
Prammananan, T.3
Sturmfels, A.4
Kappler, M.5
Pletschette, M.6
Böttger, E.C.7
-
37
-
-
77955362067
-
Directed mutagenesis of Mycobacterium smegmatis 16S rRNA to reconstruct the in-vivo evolution of aminoglycoside resistance in Mycobacterium tuberculosis
-
Shcherbakov, D., Akbergenov, R., Matt, T., Sander, P., Andersson, D.I., and Böttger, E.C. (2010) Directed mutagenesis of Mycobacterium smegmatis 16S rRNA to reconstruct the in-vivo evolution of aminoglycoside resistance in Mycobacterium tuberculosis. Mol. Microbiol., 77, 830-840.
-
(2010)
Mol. Microbiol
, vol.77
, pp. 830-840
-
-
Shcherbakov, D.1
Akbergenov, R.2
Matt, T.3
Sander, P.4
Andersson, D.I.5
Böttger, E.C.6
-
38
-
-
84866377800
-
Crystal structure and specific binding mode of sisomicin to the bacterial ribosomal decoding site
-
Kondo, J., Koganei, M., and Kasahara, T. (2012) Crystal structure and specific binding mode of sisomicin to the bacterial ribosomal decoding site. ACS Med. Chem. Lett., 3, 741-744.
-
(2012)
ACS Med. Chem. Lett
, vol.3
, pp. 741-744
-
-
Kondo, J.1
Koganei, M.2
Kasahara, T.3
-
39
-
-
0032212026
-
Deciphering RNA recognition: Aminoglycoside binding to the hammerhead ribozyme
-
Tor, Y., Hermann, T., and Westhof, E. (1998) Deciphering RNA recognition: aminoglycoside binding to the hammerhead ribozyme. Chem. Biol., 5, R277-R283.
-
(1998)
Chem. Biol
, vol.5
, pp. R277-R283
-
-
Tor, Y.1
Hermann, T.2
Westhof, E.3
-
40
-
-
67649165917
-
-
(ed D.P. Arya), Wiley-Interscience, Hoboken, NJ
-
Shakya, T. and Wright, G.D. (2007) in Aminoglycoside Antibiotics from Chemical Biology to Drug Discovery (ed D.P. Arya), Wiley-Interscience, Hoboken, NJ, pp. 119-140.
-
(2007)
Aminoglycoside Antibiotics from Chemical Biology to Drug Discovery
, pp. 119-140
-
-
Shakya, T.1
Wright, G.D.2
-
41
-
-
37849013607
-
Designer aminoglycosides: The race to develop improved antibiotics and compounds for the treatment of human genetic diseases
-
Hainrichson, M., Nudelman, I., and Baasov, T. (2007) Designer aminoglycosides: the race to develop improved antibiotics and compounds for the treatment of human genetic diseases. Org. Biomol. Chem., 6, 227-239.
-
(2007)
Org. Biomol. Chem
, vol.6
, pp. 227-239
-
-
Hainrichson, M.1
Nudelman, I.2
Baasov, T.3
-
42
-
-
34547093657
-
Aminoglycoside antibiotics: Old drugs and new therapeutic approaches
-
Hermann, T. (2007) Aminoglycoside antibiotics: old drugs and new therapeutic approaches. Cell. Mol. Life Sci., 64, 1841-1852.
-
(2007)
Cell. Mol. Life Sci
, vol.64
, pp. 1841-1852
-
-
Hermann, T.1
-
43
-
-
34247593152
-
Modifications of aminoglycoside antibiotics targeting RNA
-
Zhou, J., Wang, G., Zhang, L.H., and Ye, X.S. (2007) Modifications of aminoglycoside antibiotics targeting RNA. Med. Res. Rev., 27, 279-316.
-
(2007)
Med. Res. Rev
, vol.27
, pp. 279-316
-
-
Zhou, J.1
Wang, G.2
Zhang, L.H.3
Ye, X.S.4
-
44
-
-
0015449796
-
BB-K8, a new semisynthetic aminoglycoside antibiotic
-
Kawaguchi, H., Naito, T., Nakagawa, S., and Fujisawa, K. (1972) BB-K8, a new semisynthetic aminoglycoside antibiotic. J. Antibiot., 25, 695-708.
-
(1972)
J. Antibiot
, vol.25
, pp. 695-708
-
-
Kawaguchi, H.1
Naito, T.2
Nakagawa, S.3
Fujisawa, K.4
-
45
-
-
85086688776
-
Discovery, chemistry, and activity of amikacin
-
Kawaguchi, N. (1976) Discovery, chemistry, and activity of amikacin. J. Infect. Dis., 134, S242-S248.
-
(1976)
J. Infect. Dis
, vol.134
, pp. S242-S248
-
-
Kawaguchi, N.1
-
46
-
-
0032892950
-
Semisynthetic aminoglycoside antibiotics: Development and enzymatic modifications
-
Kondo, S. and Hotta, K. (1999) Semisynthetic aminoglycoside antibiotics: development and enzymatic modifications. J. Infect. Chemother., 5, 1-9.
-
(1999)
J. Infect. Chemother
, vol.5
, pp. 1-9
-
-
Kondo, S.1
Hotta, K.2
-
47
-
-
0034426097
-
Aminoglycosides: Perspectives on mechanisms of action and resistance and strategies to counter resistance
-
Kotra, L.P., Haddad, J., and Mobashery, S. (2000) Aminoglycosides: perspectives on mechanisms of action and resistance and strategies to counter resistance. Antimicrob. Agents Chemother., 44, 3249-3256.
-
(2000)
Antimicrob. Agents Chemother
, vol.44
, pp. 3249-3256
-
-
Kotra, L.P.1
Haddad, J.2
Mobashery, S.3
-
48
-
-
0037012422
-
Design of novel antibiotics that bind to the ribosomal acyltransfer site
-
Haddad, J., Kotra, L.P., Llano-Sotelo, B., Kim, C., Azucena, E.F. Jr., Liu, M., Vakulenko, S.B., Chow, C.S., and Mobashery, S. (2002) Design of novel antibiotics that bind to the ribosomal acyltransfer site. J. Am. Chem. Soc., 124, 3229-3237.
-
(2002)
J. Am. Chem. Soc
, vol.124
, pp. 3229-3237
-
-
Haddad, J.1
Kotra, L.P.2
Llano-Sotelo, B.3
Kim, C.4
Azucena, E.F.5
Liu, M.6
Vakulenko, S.B.7
Chow, C.S.8
Mobashery, S.9
-
49
-
-
0037467430
-
The complex of a designer antibiotic with a model aminoacyl site of the 30S ribosomal subunit revealed by X-ray crystallography
-
Russell, R.J., Murray, J.B., Lentzen, G., Haddad, J., and Mobashery, S. (2003) The complex of a designer antibiotic with a model aminoacyl site of the 30S ribosomal subunit revealed by X-ray crystallography. J. Am. Chem. Soc., 125, 3410-3411.
-
(2003)
J. Am. Chem. Soc
, vol.125
, pp. 3410-3411
-
-
Russell, R.J.1
Murray, J.B.2
Lentzen, G.3
Haddad, J.4
Mobashery, S.5
-
50
-
-
32844459761
-
Interactions of designer antibiotics and the bacterial ribosomal aminoacyl-tRNA site
-
Murray, J.B., Meroueh, S.O., Russell, R.J., Lentzen, G., Haddad, J., and Mobashery, S. (2006) Interactions of designer antibiotics and the bacterial ribosomal aminoacyl-tRNA site. Chem. Biol., 13, 129-138.
-
(2006)
Chem. Biol
, vol.13
, pp. 129-138
-
-
Murray, J.B.1
Meroueh, S.O.2
Russell, R.J.3
Lentzen, G.4
Haddad, J.5
Mobashery, S.6
-
51
-
-
84964134387
-
Streptomycin, a substance exhibiting antibiotic activity against gram-positive and gram-negative bacteria
-
Schatz, A., Bugie, E., and Waksman, S.A. (1944) Streptomycin, a substance exhibiting antibiotic activity against gram-positive and gram-negative bacteria. Proc. Soc. Exp. Biol. Med., 55, 66-69.
-
(1944)
Proc. Soc. Exp. Biol. Med
, vol.55
, pp. 66-69
-
-
Schatz, A.1
Bugie, E.2
Waksman, S.A.3
-
52
-
-
0027988447
-
Dissociation rate of cognate peptidyltRNA from the A-site of hyper-accurate and error-prone ribosomes
-
Karimi, R. and Ehrenberg, M. (1994) Dissociation rate of cognate peptidyltRNA from the A-site of hyper-accurate and error-prone ribosomes. Eur.J. Biochem., 226, 335-360.
-
(1994)
Eur.J. Biochem
, vol.226
, pp. 335-360
-
-
Karimi, R.1
Ehrenberg, M.2
-
53
-
-
0029986817
-
Dissociation rates of peptidyl-tRNA from the P-site of E. coli ribosomes
-
Karimi, R. and Ehrenberg, M. (1996) Dissociation rates of peptidyl-tRNA from the P-site of E. coli ribosomes. EMBO J., 15, 1149-1154.
-
(1996)
EMBO J
, vol.15
, pp. 1149-1154
-
-
Karimi, R.1
Ehrenberg, M.2
-
54
-
-
0030806152
-
A conformational switch in Escherichia coli 16S ribosomal RNA during decoding of messenger RNA
-
Lodmell, J.S. and Dahlberg, A.E. (1997) A conformational switch in Escherichia coli 16S ribosomal RNA during decoding of messenger RNA. Science, 277, 1262-1267.
-
(1997)
Science
, vol.277
, pp. 1262-1267
-
-
Lodmell, J.S.1
Dahlberg, A.E.2
-
55
-
-
0018141671
-
Studies on the mode of action of hygromycin B, an inhibitor of translocation in eukaryotes
-
Gonzalez, A., Jimenez, A., Vazquez, D., Davies, J.E., and Schindler, D. (1978) Studies on the mode of action of hygromycin B, an inhibitor of translocation in eukaryotes. Biochim. Biophys. Acta, 521, 459-469.
-
(1978)
Biochim. Biophys. Acta
, vol.521
, pp. 459-469
-
-
Gonzalez, A.1
Jimenez, A.2
Vazquez, D.3
Davies, J.E.4
Schindler, D.5
-
56
-
-
0034704217
-
The structural basis for the action of the antibiotics tetracycline, pactamycin, and hygromycin B on the 30S ribosomal subunit
-
Brodersen, D.E., Clemons, W.M. Jr., Carter, A.P., Morgan-Warren, R.J., Wimberly, B.T., and Ramakrishnan, V. (2000) The structural basis for the action of the antibiotics tetracycline, pactamycin, and hygromycin B on the 30S ribosomal subunit. Cell, 103, 1143-1154.
-
(2000)
Cell
, vol.103
, pp. 1143-1154
-
-
Brodersen, D.E.1
Clemons, W.M.2
Carter, A.P.3
Morgan-Warren, R.J.4
Wimberly, B.T.5
Ramakrishnan, V.6
-
57
-
-
0036566330
-
Post-termination complex disassembly by ribosome recycling factor, a functional tRNA mimic
-
Hirokawa, G., Kiel, M.C., Muto, A., Selmer, M., Raj, V.S., Liljas, A., Igarashi, K., Kaji, H., and Kaji, A. (2002) Post-termination complex disassembly by ribosome recycling factor, a functional tRNA mimic. EMBO J., 21, 2272-2281.
-
(2002)
EMBO J
, vol.21
, pp. 2272-2281
-
-
Hirokawa, G.1
Kiel, M.C.2
Muto, A.3
Selmer, M.4
Raj, V.S.5
Liljas, A.6
Igarashi, K.7
Kaji, H.8
Kaji, A.9
-
58
-
-
34547696927
-
Structural basis for aminoglycoside inhibition of bacterial ribosome recycling
-
Borovinskaya, M.A., Pai, R.D., Zhang, W., Schuwirth, B.S., Holton, J.M., Hirokawa, G., Kaji, H., Kaji, A., and Cate, J.H. (2007) Structural basis for aminoglycoside inhibition of bacterial ribosome recycling. Nat. Struct. Mol. Biol., 14, 727-732.
-
(2007)
Nat. Struct. Mol. Biol
, vol.14
, pp. 727-732
-
-
Borovinskaya, M.A.1
Pai, R.D.2
Zhang, W.3
Schuwirth, B.S.4
Holton, J.M.5
Hirokawa, G.6
Kaji, H.7
Kaji, A.8
Cate, J.H.9
-
59
-
-
0025008960
-
Ribosomal RNA and protein mutants resistant to spectinomycin
-
Bilgin, N., Richter, A., Ehrenberg, M., Dahlberg, A.E., and Kurland, C.G. (1990) Ribosomal RNA and protein mutants resistant to spectinomycin. EMBO J., 9, 735-739.
-
(1990)
EMBO J
, vol.9
, pp. 735-739
-
-
Bilgin, N.1
Richter, A.2
Ehrenberg, M.3
Dahlberg, A.E.4
Kurland, C.G.5
-
60
-
-
35348857512
-
A steric block in translation caused by the antibiotic spectinomycin
-
Borovinskaya, M.A., Shoji, S., Holton, J.M., Fredrick, K., and Cate, J.H. (2007) A steric block in translation caused by the antibiotic spectinomycin. ACS Chem. Biol., 2, 545-552.
-
(2007)
ACS Chem. Biol
, vol.2
, pp. 545-552
-
-
Borovinskaya, M.A.1
Shoji, S.2
Holton, J.M.3
Fredrick, K.4
Cate, J.H.5
-
61
-
-
0013840463
-
Kasugamycin, a new antibiotic
-
Umezawa, H., Hamada, M., Suhara, Y., Hashimoto, T., and Ikekawa, T. (1965) Kasugamycin, a new antibiotic. Antimicrob. Agents Chemother., 5, 753-757.
-
(1965)
Antimicrob. Agents Chemother
, vol.5
, pp. 753-757
-
-
Umezawa, H.1
Hamada, M.2
Suhara, Y.3
Hashimoto, T.4
Ikekawa, T.5
-
62
-
-
0042249823
-
Antimicrobial activity of kasugamycin
-
Hamada, M., Hashimoto, T., Takahashi, T., Yokoyama, S., Miyake, M., Takeuchi, T., Okami, Y., and Umezawa, H. (1965) Antimicrobial activity of kasugamycin. J. Antibiot. Ser. A, 18, 104-106.
-
(1965)
J. Antibiot. Ser. A
, vol.18
, pp. 104-106
-
-
Hamada, M.1
Hashimoto, T.2
Takahashi, T.3
Yokoyama, S.4
Miyake, M.5
Takeuchi, T.6
Okami, Y.7
Umezawa, H.8
-
63
-
-
33749531968
-
The antibiotic kasugamycin mimics mRNA nucleotides to destabilize tRNA binding and inhibit canonical translation initiation
-
Schluenzen, F., Takemoto, C., Wilson, D.N., Kaminishi, T., Harms, J.M., Hanawa-Suetsugu, K., Szaflarski, W., Kawazoe, M., Shirouzu, M., Nierhaus, K.H., Yokoyama, S., and Fucini, P. (2006) The antibiotic kasugamycin mimics mRNA nucleotides to destabilize tRNA binding and inhibit canonical translation initiation. Nat. Struct. Mol. Biol., 13, 871-878.
-
(2006)
Nat. Struct. Mol. Biol
, vol.13
, pp. 871-878
-
-
Schluenzen, F.1
Takemoto, C.2
Wilson, D.N.3
Kaminishi, T.4
Harms, J.M.5
Hanawa-Suetsugu, K.6
Szaflarski, W.7
Kawazoe, M.8
Shirouzu, M.9
Nierhaus, K.H.10
Yokoyama, S.11
Fucini, P.12
-
64
-
-
0014210208
-
Partial removal of bound transfer RNA from polysomes engaged in protein synthesis in vitro after addition of tetracycline
-
Maxwell, I.H. (1967) Partial removal of bound transfer RNA from polysomes engaged in protein synthesis in vitro after addition of tetracycline. Biochim. Biophys. Acta, 138, 337-346.
-
(1967)
Biochim. Biophys. Acta
, vol.138
, pp. 337-346
-
-
Maxwell, I.H.1
-
65
-
-
0022881139
-
Tetracycline can inhibit tRNA binding to the ribosomal P site as well as to the A site
-
Geigenmüller, U. and Nierhaus, K.H. (1986) Tetracycline can inhibit tRNA binding to the ribosomal P site as well as to the A site. Eur. J. Biochem., 161, 723-726.
-
(1986)
Eur. J. Biochem
, vol.161
, pp. 723-726
-
-
Geigenmüller, U.1
Nierhaus, K.H.2
-
66
-
-
17744377418
-
Crystal structures of complexes of the small ribosomal subunit with tetracycline, edeine and IF3
-
Pioletti, M., Schlünzen, F., Harms, J., Zarivach, R., Glühmann, M., Avila, H., Bashan, A., Bartels, H., Auerbach, T., Jacobi, C., Hartsch, T., Yonath, A., and Franceschi, F. (2001) Crystal structures of complexes of the small ribosomal subunit with tetracycline, edeine and IF3. EMBO J., 20, 1829-1839.
-
(2001)
EMBO J
, vol.20
, pp. 1829-1839
-
-
Pioletti, M.1
Schlünzen, F.2
Harms, J.3
Zarivach, R.4
Glühmann, M.5
Avila, H.6
Bashan, A.7
Bartels, H.8
Auerbach, T.9
Jacobi, C.10
Hartsch, T.11
Yonath, A.12
Franceschi, F.13
-
67
-
-
0343387682
-
Thermorubin, a new antibiotic from a thermoactinomycete
-
Craveri, R., Coronelli, C., Pagani, H., and Sensi, P. (1964) Thermorubin, a new antibiotic from a thermoactinomycete. Clin. Med. (Northfield Il), 71, 511-521.
-
(1964)
Clin. Med. (Northfield Il)
, vol.71
, pp. 511-521
-
-
Craveri, R.1
Coronelli, C.2
Pagani, H.3
Sensi, P.4
-
68
-
-
84857372570
-
The antibiotic thermorubin inhibits protein synthesis by binding to inter-subunit bridge B2a of the ribosome
-
Bulkley, D., Johnson, F., and Steitz, T.A. (2012) The antibiotic thermorubin inhibits protein synthesis by binding to inter-subunit bridge B2a of the ribosome. J. Mol. Biol., 416, 571-578.
-
(2012)
J. Mol. Biol
, vol.416
, pp. 571-578
-
-
Bulkley, D.1
Johnson, F.2
Steitz, T.A.3
|