Semisynthetic aminoglycoside antibiotics: Development and enzymatic modifications

Journal of Infection and Chemotherapy

Volumn 5, Issue 1, 1999, Pages 1-9

  Kondo, Shinichi ^a   Hotta, Kunimoto ^b  

^a INSTITUTE OF MICROBIAL CHEMISTRY   (Japan)

^b NATIONAL INSTITUTE OF INFECTIOUS DISEASES   (Japan)

Author keywords

Aminoglycoside antibiotics; Aminoglycoside modifying enzymes; Arbekacin; Resistance mechanism; Semisynthetic; Streptomyces origin

Indexed keywords

2 DEOXYSTREPTAMINE; 4 AMINO 2 HYDROXYBUTYRATE; AMIKACIN; AMINOGLYCOSIDE ANTIBIOTIC AGENT; APRAMYCIN; BETAMICIN; BUTIROSIN; BUTYRIC ACID DERIVATIVE; DESTOMYCIN; DIBEKACIN; DRUG DERIVATIVE; FORTIMICIN; GENTAMICIN C; HABEKACIN; HYGROMYCIN B; ISEPAMICIN; ISOSERINE; KANAMYCIN; KANAMYCIN B; LIVIDOMYCIN; NEOMYCIN; NETILMICIN; PAROMOMYCIN; RIBOSTAMYCIN; SISOMICIN; SPECTINOMYCIN; STREPTIDINE; STREPTOMYCIN; TOBRAMYCIN; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ANTIBIOTIC RESISTANCE; CHEMICAL MODIFICATION; DRUG ACETYLATION; DRUG DEGRADATION; DRUG DESIGN; DRUG INACTIVATION; DRUG INDICATION; DRUG STRUCTURE; DRUG SYNTHESIS; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MOLECULAR STABILITY; PHOSPHORYLATION; REACTION ANALYSIS; REVIEW; STREPTOMYCES; STRUCTURE ACTIVITY RELATION;

EID: 0032892950     PISSN: 1341321X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s101560050001     Document Type: Review

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