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Volumn 2, Issue 11, 2007, Pages 1631-1638

Crystal structure of the bacterial ribosomal decoding site complexed with a synthetic doubly functionalized paromomycin derivative: A new specific binding mode to an A-minor motif enhances in vitro antibacterial activity

(6) Kondo, Jiro b Pachamuthu, Kandasamy a François, Boris b Szychowski, Janek a Hanessian, Stephen a Westhof, Eric b

a UNIVERSITÉ DE MONTRÉAL (Canada)

b INST DE BIOL MOLEC ET CELLULAIRE (France)

Author keywords

A minor motif; Aminoglycoside; L haba group; Ribosomal decoding site; X ray analysis

Indexed keywords

ANTIINFECTIVE AGENT; BACTERIAL RNA; PAROMOMYCIN; RIBOSOME RNA;

ARTICLE; BACTERIUM; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; CONFORMATION; DRUG EFFECT; GENETICS; METABOLISM; MICROBIOLOGICAL EXAMINATION;

ANTI-BACTERIAL AGENTS; BACTERIA; BINDING SITES; MICROBIAL SENSITIVITY TESTS; MOLECULAR STRUCTURE; NUCLEIC ACID CONFORMATION; PAROMOMYCIN; RNA, BACTERIAL; RNA, RIBOSOMAL;

EID: 49649109590 PISSN: 18607179 EISSN: 18607187 Source Type: Journal
DOI: 10.1002/cmdc.200700113 Document Type: Article

Times cited : (38)

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