Crystal structure of the bacterial ribosomal decoding site complexed with amikacin containing the γ-amino-α-hydroxybutyryl (haba) group

Biochimie

Volumn 88, Issue 8, 2006, Pages 1027-1031

  Kondo, Jiro ^a   François, Boris ^a   Russell, Rupert J M ^b   Murray, James B ^b   Westhof, Eric ^a  

^a INST DE BIOL MOLEC ET CELLULAIRE   (France)

^b Vernalis PLC   (United Kingdom)

Author keywords

Aminoglycoside; Haba group; Ribosomal decoding site; X ray analysis

Indexed keywords

2 (4 HYDROXYPHENYLAZO)BENZOIC ACID; AMIKACIN; AMINOGLYCOSIDE; KANAMYCIN; OLIGONUCLEOTIDE; RNA 16S;

ARTICLE; BACTERIAL GENOME; BINDING SITE; CHEMICAL INTERACTION; CRYSTAL STRUCTURE; DNA DETERMINATION; MUTATION; NONHUMAN; RIBOSOME; RNA TRANSLATION; STRUCTURE ANALYSIS; CHEMICAL STRUCTURE; CHEMISTRY; CONFORMATION; DRUG EFFECT; GENETICS; METABOLISM; METHODOLOGY; X RAY CRYSTALLOGRAPHY;

BACTERIA (MICROORGANISMS);

AMIKACIN; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; MODELS, MOLECULAR; NUCLEIC ACID CONFORMATION; OLIGONUCLEOTIDES; RIBOSOMES; RNA, RIBOSOMAL, 16S;

EID: 33747872896     PISSN: 03009084     EISSN: 61831638     Source Type: Journal    
DOI: 10.1016/j.biochi.2006.05.017     Document Type: Article

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