Molecular recognition by glycoside pseudo base pairs and triples in an apramycin-RNA complex

Angewandte Chemie - International Edition

Volumn 44, Issue 18, 2005, Pages 2694-2700

  Han, Qing ^a   Zhao, Qiang ^a   Fish, Sarah ^a   Simonsen, Klaus B ^a,b   Vourloumis, Dionisios ^a   Froelich, Jamie M ^a   Wall, Daniel ^a   Hermann, Thomas ^a  

^a F HOFFMANN LA ROCHE LTD   (Switzerland)

^b H LUNDBECK A S   (Denmark)

Author keywords

Antibiotics; Glycosides; Molecular recognition; RNA; Structure activity relationships

Indexed keywords

ANTIBIOTICS; BACTERIA; CRYSTAL STRUCTURE; PROTEINS; RNA; SUGARS;

APRAMYCIN; GLYCOSIDE; MOLECULAR RECOGNITION; NATURAL PRODUCTS;

MOLECULAR DYNAMICS;

ANTIINFECTIVE AGENT; APRAMYCIN; DRUG DERIVATIVE; GLYCOSIDE; NEBRAMYCIN; RNA;

ARTICLE; BASE PAIRING; CHEMICAL STRUCTURE; CHEMISTRY; HYDROGEN BOND; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; X RAY CRYSTALLOGRAPHY;

ANTI-BACTERIAL AGENTS; BASE PAIRING; BASE SEQUENCE; CRYSTALLOGRAPHY, X-RAY; GLYCOSIDES; HYDROGEN BONDING; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NEBRAMYCIN; RNA;

EID: 18844413838     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/anie.200500028     Document Type: Article

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