A structural basis for the antibiotic resistance conferred by an A1408G mutation in 16SrRNA and for the antiprotozoal activity of aminoglycosides

Angewandte Chemie - International Edition

Volumn 51, Issue 2, 2012, Pages 465-468

  Kondo, Jiro ^a  

^a SOPHIA UNIVERSITY   (Japan)

Author keywords

antibiotic resistance; antibiotics; antiprotozoal activity; ribosome; RNA

Indexed keywords

16S RRNA; AMINOGLYCOSIDES; ANTIBIOTIC RESISTANCE; CARBON FRAMEWORK; GENETICIN; RIBOSOME; STRUCTURAL BASIS;

CRYSTAL STRUCTURE; RNA;

ANTIBIOTICS;

ANTIAMEBIC AGENT; ANTIBIOTIC G 418; ANTIINFECTIVE AGENT; BACTERIAL RNA; GENTAMICIN; RNA 16S;

ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIUM; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECT; GENETICS; MUTATION; X RAY CRYSTALLOGRAPHY;

AMEBICIDES; ANTI-BACTERIAL AGENTS; BACTERIA; CRYSTALLOGRAPHY, X-RAY; DRUG RESISTANCE, MICROBIAL; GENTAMICINS; MODELS, MOLECULAR; MUTATION; RNA, BACTERIAL; RNA, RIBOSOMAL, 16S;

EID: 84855467966     PISSN: 14337851     EISSN: 15213773     Source Type: Journal    
DOI: 10.1002/anie.201106084     Document Type: Article

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