Oral films as breakthrough tools for oral delivery of proteins/peptides

Journal of Controlled Release

Volumn 211, Issue , 2015, Pages 63-73

  Castro, Pedro M ^a,b   Fonte, Pedro ^b,c   Sousa, Flávia ^b   Madureira, Ana Raquel ^a   Sarmento, Bruno ^b,d,e   Pintado, Manuela E ^a  

^a UNIVERSIDADE CATÓLICA PORTUGUESA   (Portugal)

^b INSTITUTO DE INVESTIGAÇÃO E FORMAÇÃO AVANÇADA EM CIÊNCIAS E TECNOLOGIAS DA SAÚDE   (Portugal)

^c UNIVERSITY OF PORTO   (Portugal)

^d UNIVERSITY OF PORTO   (Portugal)

^e INEB INSTITUTO DE ENGENHARIA BIOMÉDICA   (Portugal)

Author keywords

Bioactive Peptides; Bioactive proteins; Bioavailability enhancement; Oral delivery; Oral films; Stability

Indexed keywords

BIOCHEMISTRY; CONVERGENCE OF NUMERICAL METHODS; MECHANICAL PERMEABILITY; PEPTIDES;

BIOACTIVE PEPTIDES; BIOACTIVE PROTEINS; BIOAVAILABILITY ENHANCEMENTS; BIOLOGICAL PERFORMANCE; INHERENT CHARACTERISTICS; ORAL DELIVERY; PHYSIOLOGICAL MECHANISMS; THERAPEUTIC PROTEIN;

PROTEINS;

ALPHA LACTALBUMIN; AMINO ACID; APOMORPHINE; ARGININE; BUSERELIN; CARBOHYDRATE; CHITOSAN; DODECYL SULFATE SODIUM; EXCIPIENT; FENTANYL; GELATIN; GUAR GUM; HYDROXYPROPYLMETHYLCELLULOSE; INSULIN; ION; LINACLOTIDE; NEUROTOXIN; NONYLPHENOXYPOLYOXYETHYLENE; OCTREOTIDE; PENETRATIN; PEPTIDES AND PROTEINS; PLECANATIDE; POLYCARBOPHIL; POLYMER; POLYOL; POLYSORBATE; SALCATONIN; STARCH; SURFACTANT; TAURODEOXYCHOLIC ACID; UNCLASSIFIED DRUG; BIOLOGICAL PRODUCT; DRUG CARRIER; PEPTIDE; PROTEIN;

DRUG BIOAVAILABILITY; DRUG DELIVERY SYSTEM; DRUG MANUFACTURE; DRUG PENETRATION; DRUG STABILITY; FILM; PATIENT COMPLIANCE; PRIORITY JOURNAL; REVIEW; TOXICITY TESTING; AMINO ACID SEQUENCE; ANIMAL; GENETICS; HUMAN; METABOLISM; MOLECULAR GENETICS; ORAL DRUG ADMINISTRATION; PROCEDURES;

ADMINISTRATION, ORAL; AMINO ACID SEQUENCE; ANIMALS; BIOLOGICAL PRODUCTS; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; HUMANS; MOLECULAR SEQUENCE DATA; PEPTIDES; PROTEINS;

EID: 84930945233     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2015.05.258     Document Type: Review

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