-
1
-
-
0029056705
-
Absorption characteristics of chemically modified-insulin derivates without fatty acids in the small and large intestine
-
Asada H, Douen T, Waki M, et al. 1995. Absorption characteristics of chemically modified-insulin derivates without fatty acids in the small and large intestine. J Pharm Sci, 94:682-7.
-
(1995)
J Pharm Sci
, vol.94
, pp. 682-687
-
-
Asada, H.1
Douen, T.2
Waki, M.3
-
3
-
-
0027972645
-
Biochemical and morphocytochemical evidence for the intestinal absorption of insulin in control and diabetic rats. Comparison between the effectiveness of duodenal and colon mucosa
-
Bendayan M, Ziv E, Gingras D, et al. 1994. Biochemical and morphocytochemical evidence for the intestinal absorption of insulin in control and diabetic rats. Comparison between the effectiveness of duodenal and colon mucosa. Diabetologia, 37:119-26.
-
(1994)
Diabetologia
, vol.37
, pp. 119-126
-
-
Bendayan, M.1
Ziv, E.2
Gingras, D.3
-
6
-
-
0037020528
-
Effects of epidermal growth factor microemulsion formulation on the healing of stress-induced gastric ulcer in rats
-
Celebi N, Turkyilmaz A, Gonul B, et al. 2002. Effects of epidermal growth factor microemulsion formulation on the healing of stress-induced gastric ulcer in rats. J Control Release, 83:197-210.
-
(2002)
J Control Release
, vol.83
, pp. 197-210
-
-
Celebi, N.1
Turkyilmaz, A.2
Gonul, B.3
-
8
-
-
33747884001
-
Biodegradable nanoparticles loaded with insulin-phospholipid complex for oral delivery: Preparation, in vitro characterization and in vivo evaluation
-
Cui F, Shi K, Zhang L, et al. 2006. Biodegradable nanoparticles loaded with insulin-phospholipid complex for oral delivery: Preparation, in vitro characterization and in vivo evaluation. J Control Release, 114:242-50.
-
(2006)
J Control Release
, vol.114
, pp. 242-250
-
-
Cui, F.1
Shi, K.2
Zhang, L.3
-
9
-
-
0031446134
-
Poly(alkyl cyanoacrylate) nanospheres for oral administration of insulin
-
Damge C, Vrancks H, Balschmidt P, et al. 1997. Poly(alkyl cyanoacrylate) nanospheres for oral administration of insulin. J Pharm Sci, 86:1407-500.
-
(1997)
J Pharm Sci
, vol.86
, pp. 1407-1500
-
-
Damge, C.1
Vrancks, H.2
Balschmidt, P.3
-
10
-
-
33751253462
-
Nanoparticles as potential oral delivery systems of proteins and vaccines: A mechanistic approach
-
des Rieux A, Fievez V, Garinot M, et al. 2006. Nanoparticles as potential oral delivery systems of proteins and vaccines: A mechanistic approach. J Control Release, 116:1-27.
-
(2006)
J Control Release
, vol.116
, pp. 1-27
-
-
des Rieux, A.1
Fievez, V.2
Garinot, M.3
-
11
-
-
0025069886
-
Controlled vaccine release in the gut-associated lymphoid tissues. I. Orally administered biodegradable microspheres target the peyer's patches
-
Eldridge JH, Hammond CJ, Meulbroek JA, et al. 1990. Controlled vaccine release in the gut-associated lymphoid tissues. I. Orally administered biodegradable microspheres target the peyer's patches. J Control Release, 11:205-14.
-
(1990)
J Control Release
, vol.11
, pp. 205-214
-
-
Eldridge, J.H.1
Hammond, C.J.2
Meulbroek, J.A.3
-
12
-
-
18044366409
-
A comparative study of the potential of solid triglyceride nanostructures coated with chitosan or poly(ethylene glycol) as carriers for oral calcitonin delivery
-
Garcia-Fuentes M, Prego C, Torres D, et al. 2005. A comparative study of the potential of solid triglyceride nanostructures coated with chitosan or poly(ethylene glycol) as carriers for oral calcitonin delivery. Eur J Pharm Sci, 25:123-33.
-
(2005)
Eur J Pharm Sci
, vol.25
, pp. 123-133
-
-
Garcia-Fuentes, M.1
Prego, C.2
Torres, D.3
-
13
-
-
0037296404
-
Design of lipid nanoparticles for the oral delivery of hydrophilic macromolecules
-
Garcia-Fuentes M, Torres D, Alonso MJ. 2003. Design of lipid nanoparticles for the oral delivery of hydrophilic macromolecules. Colloid Surface B, 27:159-68.
-
(2003)
Colloid Surface B
, vol.27
, pp. 159-168
-
-
Garcia-Fuentes, M.1
Torres, D.2
Alonso, M.J.3
-
14
-
-
18844459351
-
New surface-modified lipid nanoparticles as delivery vehicles for salmon calcitonin
-
Garcia-Fuentes M, Torres D, Alonso MJ. 2005. New surface-modified lipid nanoparticles as delivery vehicles for salmon calcitonin. Int J Pharm, 296:122-32.
-
(2005)
Int J Pharm
, vol.296
, pp. 122-132
-
-
Garcia-Fuentes, M.1
Torres, D.2
Alonso, M.J.3
-
15
-
-
0030981739
-
Pharmacokinetic considerations of new insulin formulations and routes of administration
-
Hoffman A, Ziv E. 1997. Pharmacokinetic considerations of new insulin formulations and routes of administration. Clin Pharmacokinet, 33:285-301.
-
(1997)
Clin Pharmacokinet
, vol.33
, pp. 285-301
-
-
Hoffman, A.1
Ziv, E.2
-
16
-
-
0037018963
-
Preparation of solid lipid nanopartictes with clobetasol propionate by a novel solvent diffusion method in aqueous system and physicochemical characterization
-
Hu FQ, Yuan H, Zhang HH, et al. 2002. Preparation of solid lipid nanopartictes with clobetasol propionate by a novel solvent diffusion method in aqueous system and physicochemical characterization. Int J Pharm, 239:121-8.
-
(2002)
Int J Pharm
, vol.239
, pp. 121-128
-
-
Hu, F.Q.1
Yuan, H.2
Zhang, H.H.3
-
17
-
-
0035940059
-
Recent advances in the understanding of uptake ofmicroparticulates across the gastrointestinal lymphatics
-
Hussain N, Jaitley V, Florence AT. 2001. Recent advances in the understanding of uptake ofmicroparticulates across the gastrointestinal lymphatics. Adv Drug Deliv Rev, 50:107-42.
-
(2001)
Adv Drug Deliv Rev
, vol.50
, pp. 107-142
-
-
Hussain, N.1
Jaitley, V.2
Florence, A.T.3
-
18
-
-
0034601281
-
Biodegradable nanoparticles for oral delivery of peptides: Is there a role for polymers to affect mucosal uptake?
-
Jung T, Kamm W, Breitenbach A, et al. 2000. Biodegradable nanoparticles for oral delivery of peptides: is there a role for polymers to affect mucosal uptake? Eur J Pharm Biopharm, 50:147-60.
-
(2000)
Eur J Pharm Biopharm
, vol.50
, pp. 147-160
-
-
Jung, T.1
Kamm, W.2
Breitenbach, A.3
-
19
-
-
0141894188
-
In vitro release behavior and stability of insulin in complexation hydrogels as oral drug delivery carriers
-
Kim B, Peppas NA. 2003. In vitro release behavior and stability of insulin in complexation hydrogels as oral drug delivery carriers. Int J Pharm, 266:29-37.
-
(2003)
Int J Pharm
, vol.266
, pp. 29-37
-
-
Kim, B.1
Peppas, N.A.2
-
20
-
-
0035984944
-
Pharmacokinetic and pharmacodynamic evaluation of cyclosporine an o/w-emulsion and microsphere formulations in rabbits
-
Kim SJ, Choi HK, Suh SP, et al. 2002. Pharmacokinetic and pharmacodynamic evaluation of cyclosporine an o/w-emulsion and microsphere formulations in rabbits. Eur J Pharm Sci, 15:497-502.
-
(2002)
Eur J Pharm Sci
, vol.15
, pp. 497-502
-
-
Kim, S.J.1
Choi, H.K.2
Suh, S.P.3
-
21
-
-
0035937527
-
Liposomes with phosphatidylethanol as a carrier for oral delivery of insulin: Studies in the rat
-
Kisel MA, Kulik LN, Tsybovsky IS, et al. 2001. Liposomes with phosphatidylethanol as a carrier for oral delivery of insulin: studies in the rat. Int J Pharm, 216:105-14.
-
(2001)
Int J Pharm
, vol.216
, pp. 105-114
-
-
Kisel, M.A.1
Kulik, L.N.2
Tsybovsky, I.S.3
-
22
-
-
0035287318
-
Delivery systems for penetration enhancement of peptide and protein drugs: Design considerations
-
Komplella UB, Lee VHL. 2001. Delivery systems for penetration enhancement of peptide and protein drugs: design considerations. Adv Drug Deliv Rev, 46:211-45.
-
(2001)
Adv Drug Deliv Rev
, vol.46
, pp. 211-245
-
-
Komplella, U.B.1
Lee, V.H.L.2
-
23
-
-
33846410236
-
Preparation and characterization of nanoparticles shelled with chitosan for oral insulin delivery
-
Lin YH, Mi FL, Chen CT, et al. 2007. Preparation and characterization of nanoparticles shelled with chitosan for oral insulin delivery. Biomacromolecules, 8: 146-52.
-
(2007)
Biomacromolecules
, vol.8
, pp. 146-152
-
-
Lin, Y.H.1
Mi, F.L.2
Chen, C.T.3
-
24
-
-
0028283741
-
Calcitonin and insulin in isobutilcyanoacrylate nanocapsules: Protection against proteases and effect on intestinal absorption
-
Lowe PL, Temple CS. 1994. Calcitonin and insulin in isobutilcyanoacrylate nanocapsules: Protection against proteases and effect on intestinal absorption J Pharm Pharmacol, 46:547-52.
-
(1994)
J Pharm Pharmacol
, vol.46
, pp. 547-552
-
-
Lowe, P.L.1
Temple, C.S.2
-
26
-
-
80055122601
-
-
Muller RH, Lippacher A, Gohala S. 2000. Solid lipid nanoparticles (SLN) as carrier system for the controlled release of drugs. In: Wise DL. Handbook of Pharmaceutical controlled release technology. Marcel Dekker. p 377-91.
-
Muller RH, Lippacher A, Gohala S. 2000. Solid lipid nanoparticles (SLN) as carrier system for the controlled release of drugs. In: Wise DL. Handbook of Pharmaceutical controlled release technology. Marcel Dekker. p 377-91.
-
-
-
-
27
-
-
80055122602
-
-
Muller RH, Lucks JS. 1996. Azneistoffträger aus festen Lipidteilchen feste Lipid Nanosphären SLN, European Patent 0605497: Germany
-
Muller RH, Lucks JS. 1996. Azneistoffträger aus festen Lipidteilchen feste Lipid Nanosphären (SLN). European Patent 0605497: Germany.
-
-
-
-
28
-
-
0030581141
-
Cytotoxicity of magnetite-loaded polylactide, polylactide/glycolide particles and solid lipid nanoparticles
-
Muller RH, Maaen S, Weyhers H, et al. 1996. Cytotoxicity of magnetite-loaded polylactide, polylactide/glycolide particles and solid lipid nanoparticles. Int J Pharm, 138:85-94.
-
(1996)
Int J Pharm
, vol.138
, pp. 85-94
-
-
Muller, R.H.1
Maaen, S.2
Weyhers, H.3
-
29
-
-
0030598260
-
Biodegradation of solid lipid nanoparticles as a function of lipase incubation time
-
Muller RH, Ruhl D, Runge S. 1996. Biodegradation of solid lipid nanoparticles as a function of lipase incubation time. Int J Pharm, 144:115-21.
-
(1996)
Int J Pharm
, vol.144
, pp. 115-121
-
-
Muller, R.H.1
Ruhl, D.2
Runge, S.3
-
30
-
-
0030949023
-
Cytotoxicity of Solid lipid nano-particles as a function of the lipid matrix and the surfactant
-
Muller RH, Ruhl D, Runge S, et al. 1997. Cytotoxicity of Solid lipid nano-particles as a function of the lipid matrix and the surfactant. Pharm Res, 14:458-62.
-
(1997)
Pharm Res
, vol.14
, pp. 458-462
-
-
Muller, R.H.1
Ruhl, D.2
Runge, S.3
-
31
-
-
33744973517
-
Oral bioavailability of cyclosporine: Solid lipid nanoparticles (SLN) versus drug nanocrystals
-
Muller RH, Runge S, Ravelli V, et al. 2006. Oral bioavailability of cyclosporine: solid lipid nanoparticles (SLN) versus drug nanocrystals. Int J Pharm, 317:82-9.
-
(2006)
Int J Pharm
, vol.317
, pp. 82-89
-
-
Muller, R.H.1
Runge, S.2
Ravelli, V.3
-
32
-
-
0345148806
-
Enzymatic degradation of SLN - effect of surfactant and surfactant mixtures
-
Olbrich C, Muller RH. 1999. Enzymatic degradation of SLN - effect of surfactant and surfactant mixtures. Int J Pharm, 180:31-9.
-
(1999)
Int J Pharm
, vol.180
, pp. 31-39
-
-
Olbrich, C.1
Muller, R.H.2
-
33
-
-
0036633358
-
New horizons - Alternative routes for insulin therapy
-
Owens DR. 2002. New horizons - Alternative routes for insulin therapy. Nat Rev Drug Discov, 1:529-40.
-
(2002)
Nat Rev Drug Discov
, vol.1
, pp. 529-540
-
-
Owens, DR.1
-
34
-
-
0037027876
-
Bioadhesive polysaccharide in protein delivery system: Chitosan nanoparticles improve the intestinal absorption of insulin in vivo
-
Pan Y, Li YJ, Zhao HY, et al. 2002. Bioadhesive polysaccharide in protein delivery system: chitosan nanoparticles improve the intestinal absorption of insulin in vivo. Int J Pharm, 249:139-47.
-
(2002)
Int J Pharm
, vol.249
, pp. 139-147
-
-
Pan, Y.1
Li, Y.J.2
Zhao, H.Y.3
-
35
-
-
33748353240
-
Nanocarriers: Promising Vehicle for Bioactive Drugs
-
Rawat M, Singh D, Saraf S, et al. 2006. Nanocarriers: Promising Vehicle for Bioactive Drugs. Biol Pharm Bull, 29:1790-8.
-
(2006)
Biol Pharm Bull
, vol.29
, pp. 1790-1798
-
-
Rawat, M.1
Singh, D.2
Saraf, S.3
-
37
-
-
33748934610
-
Development and validation of a rapid reversed-phase HPLC method for the determination of insulin from nanoparticulate systems
-
Sarmento B, Ribeiro A, Veiga F, et al. 2006. Development and validation of a rapid reversed-phase HPLC method for the determination of insulin from nanoparticulate systems. Biomed Chromatogr, 20:898-903.
-
(2006)
Biomed Chromatogr
, vol.20
, pp. 898-903
-
-
Sarmento, B.1
Ribeiro, A.2
Veiga, F.3
-
39
-
-
80055122619
-
-
Souto EB, Müller RH. 2007. Lipid nanoparticles (SLN and NLC) for drug delivery. In: Domb AJ, Tabata Y, Kumar MNVR, et al. Nanoparticles for pharmaceutical applications. American Scientific Publishers. p. 103-22.
-
Souto EB, Müller RH. 2007. Lipid nanoparticles (SLN and NLC) for drug delivery. In: Domb AJ, Tabata Y, Kumar MNVR, et al. Nanoparticles for pharmaceutical applications. American Scientific Publishers. p. 103-22.
-
-
-
-
40
-
-
0031918253
-
Stealth PLA-PEG Nanoparticles as Protein Carriers for Nasal Administration
-
Tobio M, Gref R, Sanchez A, et al. 1998. Stealth PLA-PEG Nanoparticles as Protein Carriers for Nasal Administration. Pharm Res, 15:270-5.
-
(1998)
Pharm Res
, vol.15
, pp. 270-275
-
-
Tobio, M.1
Gref, R.2
Sanchez, A.3
-
41
-
-
0343962248
-
The role of PEG on the stability in digestive fluids and in vivo fate of PEG-PLA nanoparticles following oral administration
-
Tobio M, Sanchez A, Vila A, et al. 2000. The role of PEG on the stability in digestive fluids and in vivo fate of PEG-PLA nanoparticles following oral administration. Colloid Surface B, 18:315-23.
-
(2000)
Colloid Surface B
, vol.18
, pp. 315-323
-
-
Tobio, M.1
Sanchez, A.2
Vila, A.3
-
42
-
-
0030612306
-
Chitosan capsules for colo-specific drug delivery: Improvement of insulin absorption from the rat colon
-
Tozaki H, Komoike J, Tada C, et al. 1997. Chitosan capsules for colo-specific drug delivery: improvement of insulin absorption from the rat colon. J Pharm Sci, 86:1016-21.
-
(1997)
J Pharm Sci
, vol.86
, pp. 1016-1021
-
-
Tozaki, H.1
Komoike, J.2
Tada, C.3
-
43
-
-
1942453805
-
Solid lipid nanoparticles for parenteral drug delivery
-
Wissing SA, Kayser O, Muller RH. 2004. Solid lipid nanoparticles for parenteral drug delivery. Adv Drug Deliv Rev, 56:1257-72.
-
(2004)
Adv Drug Deliv Rev
, vol.56
, pp. 1257-1272
-
-
Wissing, S.A.1
Kayser, O.2
Muller, R.H.3
-
44
-
-
0027988721
-
Effects of various protease inhibitors on the intestinal absorption and degradation of insulin in rats
-
Yamamoto A, Taniguchi T, Rikyuu K, et al. 1994. Effects of various protease inhibitors on the intestinal absorption and degradation of insulin in rats. Pharm Res, 11: 1496-500.
-
(1994)
Pharm Res
, vol.11
, pp. 1496-1500
-
-
Yamamoto, A.1
Taniguchi, T.2
Rikyuu, K.3
-
45
-
-
33750501785
-
Lectin-modified solid lipid nanoparticles as carriers for oral administration of insulin
-
Zhang N, Ping Q, Huang G, et al. 2006. Lectin-modified solid lipid nanoparticles as carriers for oral administration of insulin. Int J Pharm, 327:153-9.
-
(2006)
Int J Pharm
, vol.327
, pp. 153-159
-
-
Zhang, N.1
Ping, Q.2
Huang, G.3
-
46
-
-
0034657529
-
Intestinal absorption of peptides through the enterocytes
-
Ziv E, Bendayan M. 2000. Intestinal absorption of peptides through the enterocytes. Microsc Res Tech, 49:346-52.
-
(2000)
Microsc Res Tech
, vol.49
, pp. 346-352
-
-
Ziv, E.1
Bendayan, M.2
-
47
-
-
0023150470
-
Absorption of protein via the intestinal wall. A quantitative model
-
Ziv E, Lior O, Kidron M. 1987. Absorption of protein via the intestinal wall. A quantitative model. Biochem Pharmacol, 36:1035-9.
-
(1987)
Biochem Pharmacol
, vol.36
, pp. 1035-1039
-
-
Ziv, E.1
Lior, O.2
Kidron, M.3
|