Colonic absorption of salmon calcitonin using tetradecyl maltoside (TDM) as a permeation enhancer

European Journal of Pharmaceutical Sciences

Volumn 48, Issue 4-5, 2013, Pages 726-734

  Petersen, Signe Beck ^a,b   Nielsen, Lisette Gammelgaard ^b   Rahbek, Ulrik Lytt ^b   Guldbrandt, Mette ^b   Brayden, David J ^a  

^a UNIVERSITY COLLEGE DUBLIN   (Ireland)

^b NOVO NORDISK A S   (Denmark)

Author keywords

Caco 2 and HT29 MTX E12 monolayers; Epithelial drug transport; Oral bioavailability; Oral peptide delivery; Permeation enhancers; Salmon calcitonin

Indexed keywords

PENETRATION ENHANCING AGENT; SALCATONIN; TETRADECYL MALTOSIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; CELL STRAIN CACO 2; COLON; COLON ABSORPTION; COLON MUCOSA; CONTROLLED STUDY; CYTOTOXICITY; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG DELIVERY SYSTEM; DRUG PENETRATION; HISTOLOGY; HUMAN; HUMAN CELL; ILEUM; INTESTINE EPITHELIUM CELL; JEJUNUM; MONOLAYER CULTURE; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; CACO-2 CELLS; CALCITONIN; COLON; HT29 CELLS; HUMANS; INTESTINAL ABSORPTION; L-LACTATE DEHYDROGENASE; MALE; MALTOSE; RATS; RATS, WISTAR;

EID: 84873478694     PISSN: 09280987     EISSN: 18790720     Source Type: Journal    
DOI: 10.1016/j.ejps.2013.01.009     Document Type: Article

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