Comparative permeability of various chemical markers through human vaginal and buccal mucosa as well as porcine buccal and mouth floor mucosa

Archives of Oral Biology

Volumn 49, Issue 5, 2004, Pages 387-392

  Van Eyk, Armorel D ^a   Van Der Bijl, Pieter ^a  

^a UNIVERSITY OF STELLENBOSCH   (South Africa)

Author keywords

Buccal; Human; Mouth floor; Mucosa; Permeability; Porcine; Vaginal

Indexed keywords

ARECOLINE; BIOLOGICAL MARKER; CHOLINERGIC RECEPTOR STIMULATING AGENT; ESTRADIOL; VASOPRESSIN DERIVATIVE; WATER;

ADOLESCENT; ADULT; AGED; ANIMAL; ARTICLE; BUCCAL DRUG ADMINISTRATION; FEMALE; HUMAN; INTRAVAGINAL DRUG ADMINISTRATION; METABOLISM; MIDDLE AGED; MOUTH; MOUTH MUCOSA; MUCOSA; PERMEABILITY; SWINE; VAGINA;

ADMINISTRATION, BUCCAL; ADMINISTRATION, INTRAVAGINAL; ADOLESCENT; ADULT; AGED; ANIMALS; ARECOLINE; BIOLOGICAL MARKERS; CHOLINERGIC AGONISTS; ESTRADIOL; FEMALE; HUMANS; MIDDLE AGED; MOUTH; MOUTH FLOOR; MOUTH MUCOSA; MUCOUS MEMBRANE; PERMEABILITY; SWINE; VAGINA; VASOPRESSINS; WATER;

SUIDAE;

EID: 1842435177     PISSN: 00039969     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.archoralbio.2003.12.002     Document Type: Article

References (38)

1. De Vries M.E., Bodde H.E., Verhoef J.C., Junginger H.E. Developments in buccal drug delivery. Crit. Rev. Ther. Drug Carrier Syst. 8(3):1991;271-303.
2. Harris D., Robinson J.R. Drug delivery via the mucous membranes of the oral cavity. J. Pharm. Sci. 81(1):1992;1-10.
3. Senel S., Hincal A.A. Drug permeation enhancement via buccal route: possibilities and limitations. J. Control Release. 72(1-3):2001;133-144.
4. Shojaei A.H. Buccal mucosa as a route for systemic drug delivery: a review. J. Pharm. Pharm. Sci. 1(1):1998;15-30.
5. Van der Bijl P., Thompson I.O.C., Squier C.A. Comparative permeability of human vaginal and buccal mucosa to water. Eur. J. Oral. Sci. 105:1997;571-575.
6. Van der Bijl P., Van Eyk A.D., Thompson I.O.C. Permeation of 17β-estradiol through human vaginal and buccal mucosa. Oral. Surg. Oral. Med. Oral. Pathol. Oral. Radiol. Endod. 85:1998;393-398.
7. Van der Bijl P., Van Eyk A.D., Thompson I.O.C. Diffusion rates of vasopressin through human vaginal and buccal mucosa. Eur. J. Oral. Sci. 106:1998;958-962.
8. Van der Bijl P., Van Eyk A.D., Thompson I.O.C. Penetration of human vaginal and buccal mucosa by 4.4-kd and 12-kd fluorescein-isothiocyanate- labelled dextrans. Oral. Surg. Oral. Med. Oral. Pathol. Oral. Radiol. Endod. 85:1998;686-691.
9. Van der Bijl P., Van Eyk A.D. Penetration of benzo[a]pyrene through human buccal and vaginal mucosa. Oral. Surg. Oral. Med. Oral. Pathol. Oral. Radiol. Endod. 87:1999;452-455.
10. Van der Bijl P., Penkler L., Van Eyk A.D. Permeation of sumatriptan through human vaginal and buccal mucosa. Headache. 40:2000;137-141.
11. Van der Bijl P., Van Eyk A.D., Van Wyk C.W., Stander I.A. Diffusion of reduced arecoline and arecaidine through human vaginal and buccal mucosa. J. Oral. Pathol. Med. 30:2001;200-205.
12. Thompson I.O.C., Van der Bijl P., Van Wyk C.W., Van Eyk A.D. A comparative light-microscopic, electron-microscopic and chemical study of human vaginal and buccal epithelium. Arch. Oral. Biol. 46:2001;1091-1098.
13. Dowty M.E., Knuth K.E., Irons B.K., Robinson J.R. Transport of thyrotropin releasing hormone in rabbit buccal mucosa in vitro. Pharm. Res. 9(9):1992;1113-1122.
14. Johnston T.P., Rahman A., Alur H., Shah D., Mitra A.K. Permeation of unfolded basic fibroblast growth factor (bFGF) across rabbit buccal mucosa - does unfolding of bFGF enhance transport? Pharm. Res. 15(2):1998;246-253.
15. Zhang J., Maland L., Hague B., Niu S., Robertson S., Coleman D.et al. Buccal absorption of etomidate from a solid formulation in dogs. Anesth. Analg. 86(5):1998;1116-1122.
16. Mehta M., Kemppainen B.W., Stafford R.G. In vitro penetration of tritium-labelled water (THO) and [3H]PbTx-3 (a red tide toxin) through monkey buccal mucosa and skin. Toxicol. Lett. 55(2):1991;185-194.
17. Tsutsumi K., Obata Y., Takayama K., Isowa K., Nagai T. Permeation of several drugs through keratinized epithelial-free membrane of hamster cheek pouch. Int. J. Pharm. 177(1):1999;7-14.
18. Tavakoli-Saberi M.R., Audus K.L. Cultured buccal epithelium: an in vitro model derived from the hamster pouch for studying drug transport and metabolism. Pharm. Res. 6(2):1989;160-166.
19. Chang F., Wertz P.W., Squier C.A. Comparison of glycosidase activities in epidermis, palatal epithelium and buccal epithelium. Comp. Biochem. Physiol. B. 100(1):1991;137-139.
20. Squier C.A., Cox P., Wertz P.W. Lipid content and water permeability of skin and oral mucosa. J. Invest Dermatol. 96(1):1991;123-126.
21. Senel S., Hoogstraate A.J., Spies F., Verhoef J.C., Junginger H.E., Bodde H.E. Visualization of enhancing effects of bile salts on buccal penetration. Eur. J. Morphol. 31(1-2):1993;35-41.
22. Hoogstraate A.J., Cullander C., Nagelkerke J.F., Senel S., Verhoef J.C., Junginger H.E.et al. Diffusion rates and transport pathways of fluorescein thiocyanate (FITC)-labeled model compounds through buccal epithelium. Pharm. Res. 11(1):1994;83-89.
23. Law S., Wertz P.W., Swartzendruber D.C., Squier C.A. Regional variation in content, composition and organization of porcine epithelial barrier lipids revealed by thin-layer chromatography and transmission electron microscopy. Arch. Oral. Biol. 40(12):1995;1085-1091.
24. Gore A.V., Liang A.C., Chien Y.W. Comparative biomembrane permeation of tacrine using Yucatan minipigs and domestic pigs as the animal model. J. Pharm. Sci. 87(4):1998;441-447.
25. Shojaei A.H., Zhuo S.L., Li X. Transbuccal delivery of acyclovir (II): feasibility, system design, and in vitro permeation studies. J. Pharm. Pharm. Sci. 1(2):1998;66-73.
26. Junginger H.E., Hoogstraate J.A., Verhoef J.C. Recent advances in buccal drug delivery and absorption - in vitro and in vivo studies. J. Control Release. 62(1-2):1999;149-159.
27. Liu C., Xu H.N., Li X.L. In vitro permeation of tetramethylpyrazine across porcine buccal mucosa. Acta Pharmacol. Sin. 23(9):2002;792-796.
28. Nielsen H.M., Rassing M.R. TR146 cells grown on filters as a model of human buccal epithelium: III. Permeability enhancement by different pH values, different osmolality values, and bile salts. Int. J. Pharm. 185(2):1999;215-225.
29. Nielsen H.M., Rassing M.R. TR146 cells grown on filters as a model of human buccal epithelium: IV. Permeability of water, mannitol, testosterone and beta-adrenoceptor antagonists, Comparison to human, monkey and porcine buccal mucosa. Int. J. Pharm. 194(2):2000;155-167.
30. Nielsen H.M., Rassing M.R. TR146 cells grown on filters as a model of human buccal epithelium: V. Enzyme activity of the TR146 cell culture model, human buccal epithelium and porcine buccal epithelium, and permeability of leu-enkephalin. Int. J. Pharm. 200(2):2000;261-270.
31. Nielsen H.M., Rassing M.R. Nicotine permeability across the buccal TR146 cell culture model and porcine buccal mucosa in vitro: effect of pH and concentration. Eur. J. Pharm. Sci. 16(3):2002;151-157.
32. Jacobsen J., Nielsen E.B., Brondum-Nielsen K., Christensen M.E., Olin H.B., Tommerup N.et al. Filter-grown TR146 cells as an in vitro model of human buccal epithelial permeability. Eur. J. Oral. Sci. 107(2):1999;138-146.
33. Portero A., Remunan-Lopez C., Nielsen H.M. The potential of chitosan in enhancing peptide and protein absorption across the TR146 cell culture model-an in vitro model of the buccal epithelium. Pharm. Res. 19(2):2002;169-174.
34. Squier C.A. Penetration of nicotine and nitrosonornicotine across porcine oral mucosa. J. Appl. Toxicol. 6(2):1986;123-128.
35. Wertz P.W., Squier C.A. Cellular and molecular basis of barrier function in oral epithelium. Crit. Rev. Ther. Drug Carrier Syst. 8(3):1991;237-269.
36. Chen L.L., Chetty D.J., Chien Y.W. A mechanistic analysis to characterize oramucosal permeation properties. Int. J. Pharm. 184(1):1999;63-72.
37. Lesch C.A., Squier C.A., Cruchley A., Williams D.M., Speight P. The permeability of human oral mucosa and skin to water. J. Dent Res. 68(9):1989;1345-1349.
38. Van der Bijl P., Van Eyk A.D., Thompson I.O.C. Effects of freezing on the permeability of human buccal and vaginal mucosa. S. Afr. J. Sci. 94:1998;499-502.