-
1
-
-
35848941716
-
Lantibiotics: peptides of diverse structure and function
-
Willey JM, van der Donk WA. 2007. Lantibiotics: peptides of diverse structure and function. Annu Rev Microbiol 61:477-501. http://dx.doi.org/10.1146/annurev.micro.61.080706.093501.
-
(2007)
Annu Rev Microbiol
, vol.61
, pp. 477-501
-
-
Willey, J.M.1
van der Donk, W.A.2
-
2
-
-
84861649020
-
Discovery, biosynthesis, and engineering of lantipeptides
-
Knerr PJ, van der Donk WA. 2012. Discovery, biosynthesis, and engineering of lantipeptides. Annu Rev Biochem 81:479-505. http://dx.doi.org/10.1146/annurev-biochem-060110-113521.
-
(2012)
Annu Rev Biochem
, vol.81
, pp. 479-505
-
-
Knerr, P.J.1
van der Donk, W.A.2
-
3
-
-
65949089371
-
Lantibiotics: mode of action, biosynthesis and bioengineering
-
Bierbaum G, Sahl HG. 2009. Lantibiotics: mode of action, biosynthesis and bioengineering. Curr Pharm Biotechnol 10:2-18. http://dx.doi.org/10.2174/138920109787048616.
-
(2009)
Curr Pharm Biotechnol
, vol.10
, pp. 2-18
-
-
Bierbaum, G.1
Sahl, H.G.2
-
4
-
-
79251639867
-
Fundamental functionality: recent developments in understanding the structure-activity relationships of lantibiotic peptides
-
Ross AC, Vederas JC. 2011. Fundamental functionality: recent developments in understanding the structure-activity relationships of lantibiotic peptides. J Antibiot 64:27-34. http://dx.doi.org/10.1038/ja.2010.136.
-
(2011)
J Antibiot
, vol.64
, pp. 27-34
-
-
Ross, A.C.1
Vederas, J.C.2
-
6
-
-
84892517022
-
Lantibiotics: promising candidates for future applications in health care
-
Dischinger J, Basi Chipalu S, Bierbaum G. 2014. Lantibiotics: promising candidates for future applications in health care. Int J Med Microbiol 304:51-62. http://dx.doi.org/10.1016/j.ijmm.2013.09.003.
-
(2014)
Int J Med Microbiol
, vol.304
, pp. 51-62
-
-
Dischinger, J.1
Basi Chipalu, S.2
Bierbaum, G.3
-
7
-
-
13844316746
-
Enterococcal cytolysin: a novel two component peptide system that serves as a bacterial defense against eukaryotic and prokaryotic cells
-
Cox CR, Coburn PS, Gilmore MS. 2005. Enterococcal cytolysin: a novel two component peptide system that serves as a bacterial defense against eukaryotic and prokaryotic cells. Curr Protein Pept Sci 6:77-84. http://dx.doi.org/10.2174/1389203053027557.
-
(2005)
Curr Protein Pept Sci
, vol.6
, pp. 77-84
-
-
Cox, C.R.1
Coburn, P.S.2
Gilmore, M.S.3
-
8
-
-
0023912839
-
Prepeptide sequence of epidermin, a ribosomally synthesized antibiotic with four sulphide-rings
-
Schnell N, Entian KD, Schneider U, Götz F, Zahner H, Kellner R, Jung G. 1988. Prepeptide sequence of epidermin, a ribosomally synthesized antibiotic with four sulphide-rings. Nature 333:276-278. http://dx.doi.org/10.1038/333276a0.
-
(1988)
Nature
, vol.333
, pp. 276-278
-
-
Schnell, N.1
Entian, K.D.2
Schneider, U.3
Götz, F.4
Zahner, H.5
Kellner, R.6
Jung, G.7
-
9
-
-
84870918230
-
Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature
-
Arnison PG, Bibb MJ, Bierbaum G, Bowers AA, Bugni TS, Bulaj G, Camarero JA, Campopiano DJ, Challis GL, Clardy J, Cotter PD, Craik DJ, Dawson M, Dittmann E, Donadio S, Dorrestein PC, Entian K-D, Fischbach MA, Garavelli JS, Göransson U, Gruber CW, Haft DH, Hemscheidt TK, Hertweck C, Hill C, Horswill AR, Jaspars M, Kelly WL, Klinman JP, Kuipers OP, Link AJ, Liu W, Marahiel MA, Mitchell DA, Moll GN, Moore BS, Müller R, Nair SK, Nes IF, Norris GE, Olivera BM, Onaka H, Patchett ML, Piel J, Reaney MJT, Rebuffat S, et al. 2013. Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature. Nat Prod Rep 30:108-160. http://dx.doi.org/10.1039/C2NP20085F.
-
(2013)
Nat Prod Rep
, vol.30
, pp. 108-160
-
-
Arnison, P.G.1
Bibb, M.J.2
Bierbaum, G.3
Bowers, A.A.4
Bugni, T.S.5
Bulaj, G.6
Camarero, J.A.7
Campopiano, D.J.8
Challis, G.L.9
Clardy, J.10
Cotter, P.D.11
Craik, D.J.12
Dawson, M.13
Dittmann, E.14
Donadio, S.15
Dorrestein, P.C.16
Entian, K.-D.17
Fischbach, M.A.18
Garavelli, J.S.19
Göransson, U.20
Gruber, C.W.21
Haft, D.H.22
Hemscheidt, T.K.23
Hertweck, C.24
Hill, C.25
Horswill, A.R.26
Jaspars, M.27
Kelly, W.L.28
Klinman, J.P.29
Kuipers, O.P.30
Link, A.J.31
Liu, W.32
Marahiel, M.A.33
Mitchell, D.A.34
Moll, G.N.35
Moore, B.S.36
Müller, R.37
Nair, S.K.38
Nes, I.F.39
Norris, G.E.40
Olivera, B.M.41
Onaka, H.42
Patchett, M.L.43
Piel, J.44
Reaney, M.J.T.45
Rebuffat, S.46
more..
-
10
-
-
74049115080
-
Follow the leader: the use of leader peptides to guide natural product biosynthesis
-
Oman TJ, van der Donk WA. 2010. Follow the leader: the use of leader peptides to guide natural product biosynthesis. Nat Chem Biol 6:9-18. http://dx.doi.org/10.1038/nchembio.286.
-
(2010)
Nat Chem Biol
, vol.6
, pp. 9-18
-
-
Oman, T.J.1
van der Donk, W.A.2
-
11
-
-
84878574659
-
Mechanistic aspects of lanthipeptide leaders
-
Plat A, Kuipers A, Rink R, Moll GN. 2013. Mechanistic aspects of lanthipeptide leaders. Curr Protein Pept Sci 14:85-96. http://dx.doi.org/10.2174/1389203711314020001.
-
(2013)
Curr Protein Pept Sci
, vol.14
, pp. 85-96
-
-
Plat, A.1
Kuipers, A.2
Rink, R.3
Moll, G.N.4
-
13
-
-
0030046733
-
Comparison of lantibiotic gene clusters and encoded proteins
-
Siezen RJ, Kuipers OP, de Vos WM. 1996. Comparison of lantibiotic gene clusters and encoded proteins. Antonie Van Leeuwenhoek 69:171-184. http://dx.doi.org/10.1007/BF00399422.
-
(1996)
Antonie Van Leeuwenhoek
, vol.69
, pp. 171-184
-
-
Siezen, R.J.1
Kuipers, O.P.2
de Vos, W.M.3
-
14
-
-
0942268866
-
Lacticin 481: in vitro reconstitution of lantibiotic synthetase activity
-
Xie L, Miller LM, Chatterjee C, Averin O, Kelleher NL, van der Donk WA. 2004. Lacticin 481: in vitro reconstitution of lantibiotic synthetase activity. Science 303:679-681. http://dx.doi.org/10.1126/science.1092600.
-
(2004)
Science
, vol.303
, pp. 679-681
-
-
Xie, L.1
Miller, L.M.2
Chatterjee, C.3
Averin, O.4
Kelleher, N.L.5
van der Donk, W.A.6
-
15
-
-
77953528770
-
In vitro biosynthesis of the prepeptide of type-III lantibiotic labyrinthopeptin A2 including formation of a C-C bond as a post-translational modification
-
Müller WM, Schmiederer T, Ensle P, Süssmuth RD. 2010. In vitro biosynthesis of the prepeptide of type-III lantibiotic labyrinthopeptin A2 including formation of a C-C bond as a post-translational modification. Angew Chem Int Ed 49:2436-2440. http://dx.doi.org/10.1002/anie.200905909.
-
(2010)
Angew Chem Int Ed
, vol.49
, pp. 2436-2440
-
-
Müller, W.M.1
Schmiederer, T.2
Ensle, P.3
Süssmuth, R.D.4
-
16
-
-
77950563372
-
Discovery of unique lanthionine synthetases reveals new mechanistic and evolutionary insights
-
Goto Y, Li B, Claesen J, Shi Y, Bibb MJ, van der Donk WA. 2010. Discovery of unique lanthionine synthetases reveals new mechanistic and evolutionary insights. PLoS Biol 8:e1000339. http://dx.doi.org/10.1371/journal.pbio.1000339.
-
(2010)
PLoS Biol
, vol.8
, pp. e1000339
-
-
Goto, Y.1
Li, B.2
Claesen, J.3
Shi, Y.4
Bibb, M.J.5
van der Donk, W.A.6
-
17
-
-
33644854595
-
Structure and mechanism of the lantibiotic cyclase involved in nisin biosynthesis
-
Li B, Yu JP, Brunzelle JS, Moll GN, van der Donk WA, Nair SK. 2006. Structure and mechanism of the lantibiotic cyclase involved in nisin biosynthesis. Science 311:1464-1467. http://dx.doi.org/10.1126/science.1121422.
-
(2006)
Science
, vol.311
, pp. 1464-1467
-
-
Li, B.1
Yu, J.P.2
Brunzelle, J.S.3
Moll, G.N.4
van der Donk, W.A.5
Nair, S.K.6
-
18
-
-
84861624891
-
Structural characterization of four prochlorosins: a novel class of lantipeptides produced by planktonic marine cyanobacteria
-
Tang W, van der Donk WA. 2012. Structural characterization of four prochlorosins: a novel class of lantipeptides produced by planktonic marine cyanobacteria. Biochemistry 51:4271-4279. http://dx.doi.org/10.1021/bi300255s.
-
(2012)
Biochemistry
, vol.51
, pp. 4271-4279
-
-
Tang, W.1
van der Donk, W.A.2
-
19
-
-
84914150307
-
High divergence of the precursor peptides in combinatorial lanthipeptide biosynthesis
-
Zhang Q, Yang X, Wang H, van der Donk WA. 2014. High divergence of the precursor peptides in combinatorial lanthipeptide biosynthesis. ACS Chem Biol 9:2686-2694. http://dx.doi.org/10.1021/cb500622c.
-
(2014)
ACS Chem Biol
, vol.9
, pp. 2686-2694
-
-
Zhang, Q.1
Yang, X.2
Wang, H.3
van der Donk, W.A.4
-
20
-
-
69449094338
-
Rational genome mining for LanM proteins leads to the identification of a novel two-peptide lantibiotic, lichenicidin
-
Begley M, Cotter PD, Hill C, Ross RP. 2009. Rational genome mining for LanM proteins leads to the identification of a novel two-peptide lantibiotic, lichenicidin. Appl Environ Microbiol 75:5451-5460. http://dx.doi.org/10.1128/AEM.00730-09.
-
(2009)
Appl Environ Microbiol
, vol.75
, pp. 5451-5460
-
-
Begley, M.1
Cotter, P.D.2
Hill, C.3
Ross, R.P.4
-
21
-
-
78649470645
-
In silico analysis highlights the frequency and diversity of type 1 lantibiotic gene clusters in genome sequenced bacteria
-
Marsh AJ, O'Sullivan O, Ross RP, Cotter PD, Hill C. 2010. In silico analysis highlights the frequency and diversity of type 1 lantibiotic gene clusters in genome sequenced bacteria. BMC Genomics 11:679. http://dx.doi.org/10.1186/1471-2164-11-679.
-
(2010)
BMC Genomics
, vol.11
, pp. 679
-
-
Marsh, A.J.1
O'Sullivan, O.2
Ross, R.P.3
Cotter, P.D.4
Hill, C.5
-
22
-
-
84898007815
-
Novel LanT associated lantibiotic clusters identified by genome database mining
-
Singh M, Sareen D. 2014. Novel LanT associated lantibiotic clusters identified by genome database mining. PLoS One 9:e91352. http://dx.doi.org/10.1371/journal.pone.0091352.
-
(2014)
PLoS One
, vol.9
, pp. e91352
-
-
Singh, M.1
Sareen, D.2
-
23
-
-
84922466451
-
A roadmap for natural product discovery based on large-scale genomics and metabolomics
-
Doroghazi JR, Albright JC, Goering AW, Ju KS, Haines RR, Tchalukov KA, Labeda DP, Kelleher NL, Metcalf WW. 2014. A roadmap for natural product discovery based on large-scale genomics and metabolomics. Nat Chem Biol 10:963-968. http://dx.doi.org/10.1038/nchembio.1659.
-
(2014)
Nat Chem Biol
, vol.10
, pp. 963-968
-
-
Doroghazi, J.R.1
Albright, J.C.2
Goering, A.W.3
Ju, K.S.4
Haines, R.R.5
Tchalukov, K.A.6
Labeda, D.P.7
Kelleher, N.L.8
Metcalf, W.W.9
-
24
-
-
19644393308
-
Bioactive microbial metabolites
-
Berdy J. 2005. Bioactive microbial metabolites. J Antibiot 58:1-26. http://dx.doi.org/10.1038/ja.2005.1.
-
(2005)
J Antibiot
, vol.58
, pp. 1-26
-
-
Berdy, J.1
-
25
-
-
84897938547
-
Discovering new bioactive molecules from microbial sources
-
Monciardini P, Iorio M, Maffioli S, Sosio M, Donadio S. 2014. Discovering new bioactive molecules from microbial sources. Microb Biotechnol 7:209-220. http://dx.doi.org/10.1111/1751-7915.12123.
-
(2014)
Microb Biotechnol
, vol.7
, pp. 209-220
-
-
Monciardini, P.1
Iorio, M.2
Maffioli, S.3
Sosio, M.4
Donadio, S.5
-
26
-
-
80052092565
-
Nine posttranslational modifications during the biosynthesis of cinnamycin
-
Okesli A, Cooper LE, Fogle EJ, van der Donk WA. 2011. Nine posttranslational modifications during the biosynthesis of cinnamycin. J Am Chem Soc 133:13753-13760. http://dx.doi.org/10.1021/ja205783f.
-
(2011)
J Am Chem Soc
, vol.133
, pp. 13753-13760
-
-
Okesli, A.1
Cooper, L.E.2
Fogle, E.J.3
van der Donk, W.A.4
-
27
-
-
77955814236
-
Microbisporicin gene cluster reveals unusual features of lantibiotic biosynthesis in actinomycetes
-
Foulston LC, Bibb MJ. 2010. Microbisporicin gene cluster reveals unusual features of lantibiotic biosynthesis in actinomycetes. Proc Natl Acad Sci U S A 107:13461-13466. http://dx.doi.org/10.1073/pnas.1008285107.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 13461-13466
-
-
Foulston, L.C.1
Bibb, M.J.2
-
28
-
-
38349060901
-
Determining the structure and mode of action of microbisporicin, a potent lantibiotic active against multiresistant pathogens
-
Castiglione F, Lazzarini A, Carrano L, Corti E, Ciciliato I, Gastaldo L, Candiani P, Losi D, Marinelli F, Selva E, Parenti F. 2008. Determining the structure and mode of action of microbisporicin, a potent lantibiotic active against multiresistant pathogens. Chem Biol 15:22-31. http://dx.doi.org/10.1016/j.chembiol.2007.11.009.
-
(2008)
Chem Biol
, vol.15
, pp. 22-31
-
-
Castiglione, F.1
Lazzarini, A.2
Carrano, L.3
Corti, E.4
Ciciliato, I.5
Gastaldo, L.6
Candiani, P.7
Losi, D.8
Marinelli, F.9
Selva, E.10
Parenti, F.11
-
29
-
-
84893140996
-
Characterization of the congeners in the lantibiotic NAI-107 complex
-
Maffioli SI, Iorio M, Sosio M, Monciardini P, Gaspari E, Donadio S. 2014. Characterization of the congeners in the lantibiotic NAI-107 complex. J Nat Prod 77:79-84. http://dx.doi.org/10.1021/np400702t.
-
(2014)
J Nat Prod
, vol.77
, pp. 79-84
-
-
Maffioli, S.I.1
Iorio, M.2
Sosio, M.3
Monciardini, P.4
Gaspari, E.5
Donadio, S.6
-
30
-
-
84896737390
-
A glycosylated, labionincontaining lanthipeptide with marked antinociceptive activity
-
Iorio M, Sasso O, Maffioli SI, Bertorelli R, Monciardini P, Sosio M, Bonezzi F, Summa M, Brunati C, Bordoni R, Corti G, Tarozzo G, Piomelli D, Reggiani A, Donadio S. 2014. A glycosylated, labionincontaining lanthipeptide with marked antinociceptive activity. ACS Chem Biol 9:398-404. http://dx.doi.org/10.1021/cb400692w.
-
(2014)
ACS Chem Biol
, vol.9
, pp. 398-404
-
-
Iorio, M.1
Sasso, O.2
Maffioli, S.I.3
Bertorelli, R.4
Monciardini, P.5
Sosio, M.6
Bonezzi, F.7
Summa, M.8
Brunati, C.9
Bordoni, R.10
Corti, G.11
Tarozzo, G.12
Piomelli, D.13
Reggiani, A.14
Donadio, S.15
-
31
-
-
38449101120
-
Integration of biological networks and gene expression data using Cytoscape
-
Cline MS, Smoot M, Cerami E, Kuchinsky A, Landys N, Workman C, Christmas R, Avila-Campilo I, Creech M, Gross B, Hanspers K, Isserlin R, Kelley R, Killcoyne S, Lotia S, Maere S, Morris J, Ono K, Pavlovic V, Pico AR, Vailaya A, Wang PL, Adler A, Conklin BR, Hood L, Kuiper M, Sander C, Schmulevich I, Schwikowski B, Warner GJ, Ideker T, Bader GD. 2007. Integration of biological networks and gene expression data using Cytoscape. Nat Protoc 2:2366-2382. http://dx.doi.org/10.1038/nprot.2007.324.
-
(2007)
Nat Protoc
, vol.2
, pp. 2366-2382
-
-
Cline, M.S.1
Smoot, M.2
Cerami, E.3
Kuchinsky, A.4
Landys, N.5
Workman, C.6
Christmas, R.7
Avila-Campilo, I.8
Creech, M.9
Gross, B.10
Hanspers, K.11
Isserlin, R.12
Kelley, R.13
Killcoyne, S.14
Lotia, S.15
Maere, S.16
Morris, J.17
Ono, K.18
Pavlovic, V.19
Pico, A.R.20
Vailaya, A.21
Wang, P.L.22
Adler, A.23
Conklin, B.R.24
Hood, L.25
Kuiper, M.26
Sander, C.27
Schmulevich, I.28
Schwikowski, B.29
Warner, G.J.30
Ideker, T.31
Bader, G.D.32
more..
-
33
-
-
74949129896
-
Synthesis of the lantibiotic lactocin S using peptide cyclizations on solid phase
-
Ross AC, Liu H, Pattabiraman VR, Vederas JC. 2010. Synthesis of the lantibiotic lactocin S using peptide cyclizations on solid phase. JAmChem Soc 132:462-463. http://dx.doi.org/10.1021/ja9095945.
-
(2010)
JAmChem Soc
, vol.132
, pp. 462-463
-
-
Ross, A.C.1
Liu, H.2
Pattabiraman, V.R.3
Vederas, J.C.4
-
34
-
-
84883615133
-
Comparative genomics of actinomycetes with a focus on natural product biosynthetic genes
-
Doroghazi JR, Metcalf WW. 2013. Comparative genomics of actinomycetes with a focus on natural product biosynthetic genes. BMC Genomics 14:611. http://dx.doi.org/10.1186/1471-2164-14-611.
-
(2013)
BMC Genomics
, vol.14
, pp. 611
-
-
Doroghazi, J.R.1
Metcalf, W.W.2
-
35
-
-
84924333909
-
Intraspecies comparison of Streptomyces pratensis genomes reveals high levels of recombination and gene conservation between strains of disparate geographic origin
-
Doroghazi JR, Buckley DH. 2014. Intraspecies comparison of Streptomyces pratensis genomes reveals high levels of recombination and gene conservation between strains of disparate geographic origin. BMC Genomics 15:970. http://dx.doi.org/10.1186/1471-2164-15-970.
-
(2014)
BMC Genomics
, vol.15
, pp. 970
-
-
Doroghazi, J.R.1
Buckley, D.H.2
-
36
-
-
84892704003
-
Insights into the evolution of lanthipeptide biosynthesis
-
Yu Y, Zhang Q, van der Donk WA. 2013. Insights into the evolution of lanthipeptide biosynthesis. Protein Sci 22:1478-1489. http://dx.doi.org/10.1002/pro.2358.
-
(2013)
Protein Sci
, vol.22
, pp. 1478-1489
-
-
Yu, Y.1
Zhang, Q.2
van der Donk, W.A.3
-
37
-
-
37349086129
-
Two-peptide lantibiotics: a medical perspective
-
Lawton EM, Ross RP, Hill C, Cotter PD. 2007. Two-peptide lantibiotics: a medical perspective. Mini Rev Med Chem 7:1236-1247. http://dx.doi.org/10.2174/138955707782795638.
-
(2007)
Mini Rev Med Chem
, vol.7
, pp. 1236-1247
-
-
Lawton, E.M.1
Ross, R.P.2
Hill, C.3
Cotter, P.D.4
-
38
-
-
76249088835
-
Labyrinthopeptins: a new class of carbacyclic lantibiotics
-
Meindl K, Schmiederer T, Schneider K, Reicke A, Butz D, Keller S, Guhring H, Vertesy L, Wink J, Hoffmann H, Bronstrup M, Sheldrick GM, Süssmuth RD. 2010. Labyrinthopeptins: a new class of carbacyclic lantibiotics. Angew Chem Int Ed Engl 49:1151-1154. http://dx.doi.org/10.1002/anie.200905773.
-
(2010)
Angew Chem Int Ed Engl
, vol.49
, pp. 1151-1154
-
-
Meindl, K.1
Schmiederer, T.2
Schneider, K.3
Reicke, A.4
Butz, D.5
Keller, S.6
Guhring, H.7
Vertesy, L.8
Wink, J.9
Hoffmann, H.10
Bronstrup, M.11
Sheldrick, G.M.12
Süssmuth, R.D.13
-
39
-
-
84861445578
-
Characterization of new class III lantibiotics- erythreapeptin, avermipeptin and griseopeptin from Saccharopolyspora erythraea, Streptomyces avermitilis and Streptomyces griseus demonstrates stepwise N-terminal leader processing
-
Völler GH, Krawczyk JM, Pesic A, Krawczyk B, Nachtigall J, Süssmuth RD. 2012. Characterization of new class III lantibiotics- erythreapeptin, avermipeptin and griseopeptin from Saccharopolyspora erythraea, Streptomyces avermitilis and Streptomyces griseus demonstrates stepwise N-terminal leader processing. Chembiochem 13:1174-1183. http://dx.doi.org/10.1002/cbic.201200118.
-
(2012)
Chembiochem
, vol.13
, pp. 1174-1183
-
-
Völler, G.H.1
Krawczyk, J.M.2
Pesic, A.3
Krawczyk, B.4
Nachtigall, J.5
Süssmuth, R.D.6
-
40
-
-
84855464651
-
Congeneric lantibiotics from ribosomal in vivo peptide synthesis with noncanonical amino acids
-
Oldach F, Al Toma R, Kuthning A, Caetano T, Mendo S, Budisa N, Süssmuth RD. 2012. Congeneric lantibiotics from ribosomal in vivo peptide synthesis with noncanonical amino acids. Angew Chem Int Ed Engl 51:415-418. http://dx.doi.org/10.1002/anie.201106154.
-
(2012)
Angew Chem Int Ed Engl
, vol.51
, pp. 415-418
-
-
Oldach, F.1
Al Toma, R.2
Kuthning, A.3
Caetano, T.4
Mendo, S.5
Budisa, N.6
Süssmuth, R.D.7
-
41
-
-
84868094646
-
Biosynthesis of the class III lantipeptide catenulipeptin
-
Wang H, van der Donk WA. 2012. Biosynthesis of the class III lantipeptide catenulipeptin. ACS Chem Biol 7:1529-1535. http://dx.doi.org/10.1021/cb3002446.
-
(2012)
ACS Chem Biol
, vol.7
, pp. 1529-1535
-
-
Wang, H.1
van der Donk, W.A.2
-
42
-
-
84872906665
-
Heterologous expression and engineering studies of labyrinthopeptins, class III lantibiotics from Actinomadura namibiensis
-
Krawczyk JM, Völler GH, Krawczyk B, Kretz J, Brönstrup M, Süssmuth RD. 2013. Heterologous expression and engineering studies of labyrinthopeptins, class III lantibiotics from Actinomadura namibiensis. Chem Biol 20: 111-122. http://dx.doi.org/10.1016/j.chembiol.2012.10.023.
-
(2013)
Chem Biol
, vol.20
, pp. 111-122
-
-
Krawczyk, J.M.1
Völler, G.H.2
Krawczyk, B.3
Kretz, J.4
Brönstrup, M.5
Süssmuth, R.D.6
-
43
-
-
0035282866
-
Radical SAM, a novel protein superfamily linking unresolved steps in familiar biosynthetic pathways with radical mechanisms: functional characterization using new analysis and information visualization methods
-
Sofia HJ, Chen G, Hetzler BG, Reyes-Spindola JF, Miller NE. 2001. Radical SAM, a novel protein superfamily linking unresolved steps in familiar biosynthetic pathways with radical mechanisms: functional characterization using new analysis and information visualization methods. Nucleic Acids Res 29:1097-1106. http://dx.doi.org/10.1093/nar/29.5.1097.
-
(2001)
Nucleic Acids Res
, vol.29
, pp. 1097-1106
-
-
Sofia, H.J.1
Chen, G.2
Hetzler, B.G.3
Reyes-Spindola, J.F.4
Miller, N.E.5
-
45
-
-
29444457743
-
Posttranslational conversion of L-serines to D-alanines is vital for optimal production and activity of the lantibiotic lacticin 3147
-
Cotter PD, O'Connor PM, Draper LA, Lawton EM, Deegan LH, Hill C, Ross RP. 2005. Posttranslational conversion of L-serines to D-alanines is vital for optimal production and activity of the lantibiotic lacticin 3147. Proc Natl Acad Sci U S A 102:18584-18589. http://dx.doi.org/10.1073/pnas.0509371102.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 18584-18589
-
-
Cotter, P.D.1
O'Connor, P.M.2
Draper, L.A.3
Lawton, E.M.4
Deegan, L.H.5
Hill, C.6
Ross, R.P.7
-
46
-
-
84855960442
-
Homologues and bioengineered derivatives of LtnJ vary in ability to form D-alanine in the lantibiotic lacticin 3147
-
Suda S, Lawton EM, Wistuba D, Cotter PD, Hill C, Ross RP. 2012. Homologues and bioengineered derivatives of LtnJ vary in ability to form D-alanine in the lantibiotic lacticin 3147. J Bacteriol 194:708-714. http://dx.doi.org/10.1128/JB.06185-11.
-
(2012)
J Bacteriol
, vol.194
, pp. 708-714
-
-
Suda, S.1
Lawton, E.M.2
Wistuba, D.3
Cotter, P.D.4
Hill, C.5
Ross, R.P.6
-
47
-
-
84908033373
-
Structure and biosynthesis of carnolysin, a homologue of enterococcal cytolysin with D-amino acids
-
Lohans CT, Li J L, Vederas JC. 2014. Structure and biosynthesis of carnolysin, a homologue of enterococcal cytolysin with D-amino acids. J Am Chem Soc 136:13150-13153. http://dx.doi.org/10.1021/ja5070813.
-
(2014)
J Am Chem Soc
, vol.136
, pp. 13150-13153
-
-
Lohans, C.T.1
Li, J.L.2
Vederas, J.C.3
-
48
-
-
33751204753
-
Discovery and in vitro biosynthesis of haloduracin, a two-component lantibiotic
-
McClerren AL, Cooper LE, Quan C, Thomas PM, Kelleher NL, van der Donk WA. 2006. Discovery and in vitro biosynthesis of haloduracin, a two-component lantibiotic. Proc Natl Acad Sci U S A 103:17243-17248. http://dx.doi.org/10.1073/pnas.0606088103.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 17243-17248
-
-
McClerren, A.L.1
Cooper, L.E.2
Quan, C.3
Thomas, P.M.4
Kelleher, N.L.5
van der Donk, W.A.6
-
49
-
-
69449097013
-
Production of the novel two-peptide lantibiotic lichenicidin by Bacillus licheniformis DSM 13
-
Dischinger J, Josten M, Szekat C, Sahl HG, Bierbaum G. 2009. Production of the novel two-peptide lantibiotic lichenicidin by Bacillus licheniformis DSM 13. PLoS One 4:e6788. http://dx.doi.org/10.1371/journal.pone.0006788.
-
(2009)
PLoS One
, vol.4
, pp. e6788
-
-
Dischinger, J.1
Josten, M.2
Szekat, C.3
Sahl, H.G.4
Bierbaum, G.5
-
50
-
-
77955016145
-
Isolation, structure elucidation, and synergistic antibacterial activity of a novel two-component lantibiotic lichenicidin from Bacillus licheniformis VK21
-
Shenkarev ZO, Finkina EI, Nurmukhamedova EK, Balandin SV, Mineev KS, Nadezhdin KD, Yakimenko ZA, Tagaev AA, Temirov YV, Arseniev AS, Ovchinnikova TV. 2010. Isolation, structure elucidation, and synergistic antibacterial activity of a novel two-component lantibiotic lichenicidin from Bacillus licheniformis VK21. Biochemistry 49:6462-6472. http://dx.doi.org/10.1021/bi100871b.
-
(2010)
Biochemistry
, vol.49
, pp. 6462-6472
-
-
Shenkarev, Z.O.1
Finkina, E.I.2
Nurmukhamedova, E.K.3
Balandin, S.V.4
Mineev, K.S.5
Nadezhdin, K.D.6
Yakimenko, Z.A.7
Tagaev, A.A.8
Temirov, Y.V.9
Arseniev, A.S.10
Ovchinnikova, T.V.11
-
51
-
-
79251579302
-
Heterologous expression, biosynthesis, and mutagenesis of type II lantibiotics from Bacillus licheniformis in Escherichia coli
-
Caetano T, Krawczyk JM, Mosker E, Süssmuth RD, Mendo S. 2011. Heterologous expression, biosynthesis, and mutagenesis of type II lantibiotics from Bacillus licheniformis in Escherichia coli. Chem Biol 18:90-100. http://dx.doi.org/10.1016/j.chembiol.2010.11.010.
-
(2011)
Chem Biol
, vol.18
, pp. 90-100
-
-
Caetano, T.1
Krawczyk, J.M.2
Mosker, E.3
Süssmuth, R.D.4
Mendo, S.5
-
52
-
-
33846923183
-
Type II polyketide synthases: gaining a deeper insight into enzymatic teamwork
-
Hertweck C, Luzhetskyy A, Rebets Y, Bechthold A. 2007. Type II polyketide synthases: gaining a deeper insight into enzymatic teamwork. Nat Prod Rep 24:162-190. http://dx.doi.org/10.1039/B507395M.
-
(2007)
Nat Prod Rep
, vol.24
, pp. 162-190
-
-
Hertweck, C.1
Luzhetskyy, A.2
Rebets, Y.3
Bechthold, A.4
-
53
-
-
0029586252
-
Structure of cytochrome P450eryF involved in erythromycin biosynthesis
-
Cupp-Vickery JR, Poulos TL. 1995. Structure of cytochrome P450eryF involved in erythromycin biosynthesis. Nat Struct Biol 2:144-153. http://dx.doi.org/10.1038/nsb0295-144.
-
(1995)
Nat Struct Biol
, vol.2
, pp. 144-153
-
-
Cupp-Vickery, J.R.1
Poulos, T.L.2
-
54
-
-
84925460979
-
Structure and mechanism of the tRNA-dependent lantibiotic dehydratase NisB
-
Ortega MA, Hao Y, Zhang Q, Walker MC, van der Donk WA, Nair SK. 2015. Structure and mechanism of the tRNA-dependent lantibiotic dehydratase NisB. Nature 517:509-512. http://dx.doi.org/10.1038/nature13888.
-
(2015)
Nature
, vol.517
, pp. 509-512
-
-
Ortega, M.A.1
Hao, Y.2
Zhang, Q.3
Walker, M.C.4
van der Donk, W.A.5
Nair, S.K.6
-
55
-
-
84924925641
-
A peptide ligase and the ribosome cooperate to synthesize the peptide pheganomycin
-
Noike M, Matsui T, Ooya K, Sasaki I, Ohtaki S, Hamano Y, Maruyama C, Ishikawa J, Satoh Y, Ito H, Morita H, Dairi T. 2015. A peptide ligase and the ribosome cooperate to synthesize the peptide pheganomycin. Nat Chem Biol 11:71-76. http://dx.doi.org/10.1038/nchembio.1697.
-
(2015)
Nat Chem Biol
, vol.11
, pp. 71-76
-
-
Noike, M.1
Matsui, T.2
Ooya, K.3
Sasaki, I.4
Ohtaki, S.5
Hamano, Y.6
Maruyama, C.7
Ishikawa, J.8
Satoh, Y.9
Ito, H.10
Morita, H.11
Dairi, T.12
-
56
-
-
33947395638
-
Identification of lanthionine synthase C-like protein-1 as a prominent glutathione binding protein expressed in the mammalian central nervous system
-
Chung CHY, Kurien BT, Mehta P, Mhatre M, Mou S, Pye Q N, Stewart C, West M, Williamson KS, Post J, Liu L, Wang R, Hensley K. 2007. Identification of lanthionine synthase C-like protein-1 as a prominent glutathione binding protein expressed in the mammalian central nervous system. Biochemistry 46:3262-3269. http://dx.doi.org/10.1021/bi061888s.
-
(2007)
Biochemistry
, vol.46
, pp. 3262-3269
-
-
Chung, C.H.Y.1
Kurien, B.T.2
Mehta, P.3
Mhatre, M.4
Mou, S.5
Pye Q, N.6
Stewart, C.7
West, M.8
Williamson, K.S.9
Post, J.10
Liu, L.11
Wang, R.12
Hensley, K.13
-
57
-
-
77956114547
-
Emerging biological importance of central nervous system lanthionines
-
Hensley K, Venkova K, Christov A. 2010. Emerging biological importance of central nervous system lanthionines. Molecules 15:5581-5594. http://dx.doi.org/10.3390/molecules15085581.
-
(2010)
Molecules
, vol.15
, pp. 5581-5594
-
-
Hensley, K.1
Venkova, K.2
Christov, A.3
-
58
-
-
84867257269
-
Lanthionine synthetase C-like protein 1 interacts with and inhibits cystathionine beta-synthase: a target for neuronal antioxidant defense
-
Zhong WX, Wang YB, Peng L, Ge XZ, Zhang J, Liu SS, Zhang XN, Xu ZH, Chen Z, Luo JH. 2012. Lanthionine synthetase C-like protein 1 interacts with and inhibits cystathionine beta-synthase: a target for neuronal antioxidant defense. J Biol Chem 287:34189-34201. http://dx.doi.org/10.1074/jbc.M112.383646.
-
(2012)
J Biol Chem
, vol.287
, pp. 34189-34201
-
-
Zhong, W.X.1
Wang, Y.B.2
Peng, L.3
Ge, X.Z.4
Zhang, J.5
Liu, S.S.6
Zhang, X.N.7
Xu, Z.H.8
Chen, Z.9
Luo, J.H.10
-
59
-
-
67149147296
-
Structure of human lanthionine synthetase C-like protein 1 and its interaction with Eps8 and glutathione
-
Zhang W, Wang L, Liu Y, Xu J, Zhu G, Cang H, Li X, Bartlam M, Hensley K, Li G, Rao Z, Zhang XC. 2009. Structure of human lanthionine synthetase C-like protein 1 and its interaction with Eps8 and glutathione. Genes Dev 23:1387-1392. http://dx.doi.org/10.1101/gad.1789209.
-
(2009)
Genes Dev
, vol.23
, pp. 1387-1392
-
-
Zhang, W.1
Wang, L.2
Liu, Y.3
Xu, J.4
Zhu, G.5
Cang, H.6
Li, X.7
Bartlam, M.8
Hensley, K.9
Li, G.10
Rao, Z.11
Zhang, X.C.12
-
60
-
-
84907304641
-
Developmental and activity-dependent expression of LanCL1 confers antioxidant activity required for neuronal survival
-
Huang C, Chen M, Pang D, Bi D, Zou Y, Xia X, Yang W, Luo L, Deng R, Tan H, Zhou L, Yu S, Guo L, Du X, Cui Y, Hu J, Mao Q, Worley PF, Xiao B. 2014. Developmental and activity-dependent expression of LanCL1 confers antioxidant activity required for neuronal survival. Dev Cell 30:479-487. http://dx.doi.org/10.1016/j.devcel.2014.06.011.
-
(2014)
Dev Cell
, vol.30
, pp. 479-487
-
-
Huang, C.1
Chen, M.2
Pang, D.3
Bi, D.4
Zou, Y.5
Xia, X.6
Yang, W.7
Luo, L.8
Deng, R.9
Tan, H.10
Zhou, L.11
Yu, S.12
Guo, L.13
Du, X.14
Cui, Y.15
Hu, J.16
Mao, Q.17
Worley, P.F.18
Xiao, B.19
-
61
-
-
84913529605
-
Lanthionine synthetase C-like protein 2 (LanCL2) is a novel regulator of Akt
-
Zeng M, van der Donk WA, Chen J. 2014. Lanthionine synthetase C-like protein 2 (LanCL2) is a novel regulator of Akt. Mol Biol Cell 25:3954-3961. http://dx.doi.org/10.1091/mbc.E14-01-0004.
-
(2014)
Mol Biol Cell
, vol.25
, pp. 3954-3961
-
-
Zeng, M.1
van der Donk, W.A.2
Chen, J.3
-
62
-
-
0742287185
-
Cupins: the most functionally diverse protein superfamily?
-
Dunwell JM, Purvis A, Khuri S. 2004. Cupins: the most functionally diverse protein superfamily? Phytochemistry 65:7-17. http://dx.doi.org/10.1016/j.phytochem.2003.08.016.
-
(2004)
Phytochemistry
, vol.65
, pp. 7-17
-
-
Dunwell, J.M.1
Purvis, A.2
Khuri, S.3
-
63
-
-
85027943237
-
Metagenome mining reveals polytheonamides as posttranslationally modified ribosomal peptides
-
Freeman MF, Gurgui C, Helf MJ, Morinaka BI, Uria AR, Oldham NJ, Sahl HG, Matsunaga S, Piel J. 2012. Metagenome mining reveals polytheonamides as posttranslationally modified ribosomal peptides. Science 338:387-390. http://dx.doi.org/10.1126/science.1226121.
-
(2012)
Science
, vol.338
, pp. 387-390
-
-
Freeman, M.F.1
Gurgui, C.2
Helf, M.J.3
Morinaka, B.I.4
Uria, A.R.5
Oldham, N.J.6
Sahl, H.G.7
Matsunaga, S.8
Piel, J.9
-
64
-
-
79957973597
-
Thiazole/oxazole-modified microcins: complex natural products from ribosomal templates
-
Melby JO, Nard NJ, Mitchell DA. 2011. Thiazole/oxazole-modified microcins: complex natural products from ribosomal templates. Curr Opin Chem Biol 15:369-378. http://dx.doi.org/10.1016/j.cbpa.2011.02.027.
-
(2011)
Curr Opin Chem Biol
, vol.15
, pp. 369-378
-
-
Melby, J.O.1
Nard, N.J.2
Mitchell, D.A.3
-
66
-
-
76249088902
-
Recent advances in thiopeptide antibiotic biosynthesis
-
Li C, Kelly WL. 2010. Recent advances in thiopeptide antibiotic biosynthesis. Nat Prod Rep 27:153-164. http://dx.doi.org/10.1039/B922434C.
-
(2010)
Nat Prod Rep
, vol.27
, pp. 153-164
-
-
Li, C.1
Kelly, W.L.2
-
67
-
-
84858632434
-
Three ring posttranslational circuses: insertion of oxazoles, thiazoles, and pyridines into proteinderived frameworks
-
Walsh CT, Malcolmson SJ, Young TS. 2012. Three ring posttranslational circuses: insertion of oxazoles, thiazoles, and pyridines into proteinderived frameworks. ACS Chem Biol 7:429-442. http://dx.doi.org/10.1021/cb200518n.
-
(2012)
ACS Chem Biol
, vol.7
, pp. 429-442
-
-
Walsh, C.T.1
Malcolmson, S.J.2
Young, T.S.3
-
68
-
-
84922019867
-
Discovery of a new ATP-binding motif involved in peptidic azoline biosynthesis
-
Dunbar KL, Chekan JR, Cox CL, Burkhart BJ, Nair SK, Mitchell DA. 2014. Discovery of a new ATP-binding motif involved in peptidic azoline biosynthesis. Nat Chem Biol 10:823-829. http://dx.doi.org/10.1038/nchembio.1608.
-
(2014)
Nat Chem Biol
, vol.10
, pp. 823-829
-
-
Dunbar, K.L.1
Chekan, J.R.2
Cox, C.L.3
Burkhart, B.J.4
Nair, S.K.5
Mitchell, D.A.6
-
69
-
-
18844410256
-
Patellamide A and C biosynthesis by a microcin-like pathway in Prochloron didemni, the cyanobacterial symbiont of Lissoclinum patella
-
Schmidt EW, Nelson JT, Rasko DA, Sudek S, Eisen JA, Haygood MG, Ravel J. 2005. Patellamide A and C biosynthesis by a microcin-like pathway in Prochloron didemni, the cyanobacterial symbiont of Lissoclinum patella. Proc Natl Acad Sci U S A 102:7315-7320. http://dx.doi.org/10.1073/pnas.0501424102.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 7315-7320
-
-
Schmidt, E.W.1
Nelson, J.T.2
Rasko, D.A.3
Sudek, S.4
Eisen, J.A.5
Haygood, M.G.6
Ravel, J.7
-
70
-
-
77952890038
-
Cyanobactins- ribosomal cyclic peptides produced by cyanobacteria
-
Sivonen K, Leikoski N, Fewer DP, Jokela J. 2010. Cyanobactins- ribosomal cyclic peptides produced by cyanobacteria. Appl Microbiol Biotechnol 86:1213-1225. http://dx.doi.org/10.1007/s00253-010-2482-x.
-
(2010)
Appl Microbiol Biotechnol
, vol.86
, pp. 1213-1225
-
-
Sivonen, K.1
Leikoski, N.2
Fewer, D.P.3
Jokela, J.4
-
71
-
-
84872523556
-
Biosynthesis of thiopeptide antibiotics and their pathway engineering
-
Zhang Q, Liu W. 2013. Biosynthesis of thiopeptide antibiotics and their pathway engineering. Nat Prod Rep 30:218-226. http://dx.doi.org/10.1039/C2NP20107K.
-
(2013)
Nat Prod Rep
, vol.30
, pp. 218-226
-
-
Zhang, Q.1
Liu, W.2
-
72
-
-
0029923954
-
From peptide precursors to oxazole and thiazole-containing peptide antibiotics: microcin B17 synthase
-
Li YM, Milne JC, Madison LL, Kolter R, Walsh CT. 1996. From peptide precursors to oxazole and thiazole-containing peptide antibiotics: microcin B17 synthase. Science 274:1188-1193. http://dx.doi.org/10.1126/science.274.5290.1188.
-
(1996)
Science
, vol.274
, pp. 1188-1193
-
-
Li, Y.M.1
Milne, J.C.2
Madison, L.L.3
Kolter, R.4
Walsh, C.T.5
-
73
-
-
84866449155
-
Curvopeptin: a new lanthionine-containing class III lantibiotic and its cosubstrate promiscuous synthetase
-
Krawczyk B, Völler GH, Völler J, Ensle P, Süssmuth RD. 2012. Curvopeptin: a new lanthionine-containing class III lantibiotic and its cosubstrate promiscuous synthetase. Chembiochem 13:2065-2071. http://dx.doi.org/10.1002/cbic.201200417.
-
(2012)
Chembiochem
, vol.13
, pp. 2065-2071
-
-
Krawczyk, B.1
Völler, G.H.2
Völler, J.3
Ensle, P.4
Süssmuth, R.D.5
-
74
-
-
84896737390
-
A glycosylated, labionincontaining lanthipeptide with marked antinociceptive activity
-
Iorio M, Sasso O, Maffioli SI, Bertorelli R, Monciardini P, Sosio M, Bonezzi F, Summa M, Brunati C, Bordoni R, Corti G, Tarozzo G, Piomelli D, Reggiani A, Donadio S. 2014. A glycosylated, labionincontaining lanthipeptide with marked antinociceptive activity. ACS Chem Biol 9:398. http://dx.doi.org/10.1021/cb400692w.
-
(2014)
ACS Chem Biol
, vol.9
, pp. 398
-
-
Iorio, M.1
Sasso, O.2
Maffioli, S.I.3
Bertorelli, R.4
Monciardini, P.5
Sosio, M.6
Bonezzi, F.7
Summa, M.8
Brunati, C.9
Bordoni, R.10
Corti, G.11
Tarozzo, G.12
Piomelli, D.13
Reggiani, A.14
Donadio, S.15
-
75
-
-
78651404410
-
Morphogenetic signaling molecules of the streptomycetes
-
Willey JM, Gaskell AA. 2011. Morphogenetic signaling molecules of the streptomycetes. Chem Rev 111:174-187. http://dx.doi.org/10.1021/cr1000404.
-
(2011)
Chem Rev
, vol.111
, pp. 174-187
-
-
Willey, J.M.1
Gaskell, A.A.2
|