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Volumn 7, Issue 3, 2014, Pages 209-220

Discovering new bioactive molecules from microbial sources

Author keywords

[No Author keywords available]

Indexed keywords

GE 82832; MICROBIAL PRODUCTS NOT CLASSIFIED ELSEWHERE; NAI 112; NATURAL PRODUCT; ORTHOFORMIMYCIN; PUROMYCIN; TETRACYCLINE; UNCLASSIFIED DRUG; BIOLOGICAL PRODUCT;

EID: 84897938547     PISSN: 17517907     EISSN: 17517915     Source Type: Journal    
DOI: 10.1111/1751-7915.12123     Document Type: Article
Times cited : (138)

References (72)
  • 1
    • 84867629258 scopus 로고    scopus 로고
    • Waking up Streptomyces secondary metabolism by constitutive expression of activators or genetic disruption of repressors
    • Aigle, B., and Corre, C. (2012) Waking up Streptomyces secondary metabolism by constitutive expression of activators or genetic disruption of repressors. Methods Enzymol 517: 343-366.
    • (2012) Methods Enzymol , vol.517 , pp. 343-366
    • Aigle, B.1    Corre, C.2
  • 2
    • 84870918230 scopus 로고    scopus 로고
    • Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature
    • Arnison, P.G., Bibb, M.J., Bierbaum, G., Bowers, A.A., Bugni, T.S., Bulaj, G., etal. (2013) Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature. Nat Prod Rep 30: 108-160.
    • (2013) Nat Prod Rep , vol.30 , pp. 108-160
    • Arnison, P.G.1    Bibb, M.J.2    Bierbaum, G.3    Bowers, A.A.4    Bugni, T.S.5    Bulaj, G.6
  • 3
    • 33744536067 scopus 로고    scopus 로고
    • Antibiotic discovery from actinomycetes: will a renaissance follow the decline and fall?
    • Baltz, R.H. (2005) Antibiotic discovery from actinomycetes: will a renaissance follow the decline and fall? SIM News 55: 186-196.
    • (2005) SIM News , vol.55 , pp. 186-196
    • Baltz, R.H.1
  • 4
    • 35448957251 scopus 로고    scopus 로고
    • Antimicrobials from actinomycetes: back to the future
    • Baltz, R.H. (2007) Antimicrobials from actinomycetes: back to the future. Microbe 2: 125-131.
    • (2007) Microbe , vol.2 , pp. 125-131
    • Baltz, R.H.1
  • 5
    • 54849405130 scopus 로고    scopus 로고
    • Renaissance in antibacterial discovery from actinomycetes
    • Baltz, R.H. (2008) Renaissance in antibacterial discovery from actinomycetes. Curr Opin Pharmacol 8: 557-563.
    • (2008) Curr Opin Pharmacol , vol.8 , pp. 557-563
    • Baltz, R.H.1
  • 6
    • 77957774503 scopus 로고    scopus 로고
    • Recent application of metagenomic approaches toward the discovery of antimicrobials and other bioactive small molecules
    • Banik, J.J., and Brady, S.F. (2010) Recent application of metagenomic approaches toward the discovery of antimicrobials and other bioactive small molecules. Curr Opin Microbiol 13: 603-609.
    • (2010) Curr Opin Microbiol , vol.13 , pp. 603-609
    • Banik, J.J.1    Brady, S.F.2
  • 7
    • 19644393308 scopus 로고    scopus 로고
    • Bioactive microbial metabolites
    • Bérdy, J. (2005) Bioactive microbial metabolites. J Antibiot 58: 1-26.
    • (2005) J Antibiot , vol.58 , pp. 1-26
    • Bérdy, J.1
  • 8
    • 84865683314 scopus 로고    scopus 로고
    • Thoughts and facts about antibiotics: where we are now and where we are heading
    • Bérdy, J. (2012) Thoughts and facts about antibiotics: where we are now and where we are heading. J Antibiot 65: 385-395.
    • (2012) J Antibiot , vol.65 , pp. 385-395
    • Bérdy, J.1
  • 9
    • 4544291065 scopus 로고    scopus 로고
    • Abyssomicin C-A polycyclic antibiotic from a marine Verrucosispora strain as an inhibitor of the p-aminobenzoic acid/tetrahydrofolate biosynthesis pathway
    • Bister, B., Bischoff, D., Ströbele, M., Riedlinger, J., Reicke, A., Wolter, F., etal. (2004) Abyssomicin C-A polycyclic antibiotic from a marine Verrucosispora strain as an inhibitor of the p-aminobenzoic acid/tetrahydrofolate biosynthesis pathway. Angew Chem Int Ed Engl 43: 2574-2576.
    • (2004) Angew Chem Int Ed Engl , vol.43 , pp. 2574-2576
    • Bister, B.1    Bischoff, D.2    Ströbele, M.3    Riedlinger, J.4    Reicke, A.5    Wolter, F.6
  • 11
    • 30444456799 scopus 로고    scopus 로고
    • Specific, efficient, and selective inhibition of prokaryotic translation initiation by a novel peptide antibiotic
    • Brandi, L., Fabbretti, A., La Teana, A., Abbondi, M., Losi, D., Donadio, S., and Gualerzi, C.O. (2006a) Specific, efficient, and selective inhibition of prokaryotic translation initiation by a novel peptide antibiotic. Proc Natl Acad Sci USA 103: 39-44.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 39-44
    • Brandi, L.1    Fabbretti, A.2    La Teana, A.3    Abbondi, M.4    Losi, D.5    Donadio, S.6    Gualerzi, C.O.7
  • 12
    • 33745608210 scopus 로고    scopus 로고
    • Characterization of GE82832, a peptide inhibitor of translocation interacting with bacterial 30S ribosomal subunits
    • Brandi, L., Fabbretti, A., Di Stefano, M., Lazzarini, A., Abbondi, M., and Gualerzi, C.O. (2006b) Characterization of GE82832, a peptide inhibitor of translocation interacting with bacterial 30S ribosomal subunits. RNA 12: 1262-1270.
    • (2006) RNA , vol.12 , pp. 1262-1270
    • Brandi, L.1    Fabbretti, A.2    Di Stefano, M.3    Lazzarini, A.4    Abbondi, M.5    Gualerzi, C.O.6
  • 14
    • 84866625243 scopus 로고    scopus 로고
    • Structural and functional characterization of the bacterial translocation inhibitor GE82832
    • Brandi, L., Maffioli, S., Donadio, S., Quaglia, F., Sette, M., Milón, P., etal. (2012) Structural and functional characterization of the bacterial translocation inhibitor GE82832. FEBS Lett 586: 3373-3378.
    • (2012) FEBS Lett , vol.586 , pp. 3373-3378
    • Brandi, L.1    Maffioli, S.2    Donadio, S.3    Quaglia, F.4    Sette, M.5    Milón, P.6
  • 16
    • 33747873467 scopus 로고    scopus 로고
    • Catenulispora acidiphila gen. nov., sp. nov., a novel mycelium-forming actinomycete and proposal of Catenulisporaceae fam. nov
    • Busti, E., Cavaletti, L., Monciardini, P., Schumann, P., Rohde, M., Sosio, M., and Donadio, S. (2006a) Catenulispora acidiphila gen. nov., sp. nov., a novel mycelium-forming actinomycete and proposal of Catenulisporaceae fam. nov. Int J Syst Evol Microbiol 56: 1741-1756.
    • (2006) Int J Syst Evol Microbiol , vol.56 , pp. 1741-1756
    • Busti, E.1    Cavaletti, L.2    Monciardini, P.3    Schumann, P.4    Rohde, M.5    Sosio, M.6    Donadio, S.7
  • 17
    • 33645105253 scopus 로고    scopus 로고
    • Antibiotic-producing ability by representatives of a newly discovered lineage of actinomycetes
    • Busti, E., Monciardini, P., Cavaletti, L., Bamonte, R., Lazzarini, A., Sosio, M., and Donadio, S. (2006b) Antibiotic-producing ability by representatives of a newly discovered lineage of actinomycetes. Microbiology 152: 675-683.
    • (2006) Microbiology , vol.152 , pp. 675-683
    • Busti, E.1    Monciardini, P.2    Cavaletti, L.3    Bamonte, R.4    Lazzarini, A.5    Sosio, M.6    Donadio, S.7
  • 18
    • 38349060901 scopus 로고    scopus 로고
    • Determining the structure and mode of action of microbisporicin, a potent lantibiotic active against multiresistant pathogens
    • Castiglione, F., Lazzarini, A., Carrano, L., Corti, E., Ciciliato, I., Gastaldo, L., etal. (2008) Determining the structure and mode of action of microbisporicin, a potent lantibiotic active against multiresistant pathogens. Chem Biol 15: 22-31.
    • (2008) Chem Biol , vol.15 , pp. 22-31
    • Castiglione, F.1    Lazzarini, A.2    Carrano, L.3    Corti, E.4    Ciciliato, I.5    Gastaldo, L.6
  • 19
    • 33747892407 scopus 로고    scopus 로고
    • Actinospica acidiphila gen. nov., sp. nov., and Actinospica robiniae gen. nov., sp. nov.; proposal for Actinospicaceae fam. nov. and Catenulisporinae subordo nov. in the order Actinomycetales
    • Cavaletti, L., Monciardini, P., Schumann, P., Rohde, M., Bamonte, R., Busti, E., etal. (2006) Actinospica acidiphila gen. nov., sp. nov., and Actinospica robiniae gen. nov., sp. nov.; proposal for Actinospicaceae fam. nov. and Catenulisporinae subordo nov. in the order Actinomycetales. Int J Syst Evol Microbiol 56: 1747-1753.
    • (2006) Int J Syst Evol Microbiol , vol.56 , pp. 1747-1753
    • Cavaletti, L.1    Monciardini, P.2    Schumann, P.3    Rohde, M.4    Bamonte, R.5    Busti, E.6
  • 20
    • 68149179629 scopus 로고    scopus 로고
    • New natural product biosynthetic chemistry discovered by genome mining
    • Corre, C., and Challis, G.L. (2009) New natural product biosynthetic chemistry discovered by genome mining. Nat Prod Rep 26: 977-986.
    • (2009) Nat Prod Rep , vol.26 , pp. 977-986
    • Corre, C.1    Challis, G.L.2
  • 21
    • 84881018240 scopus 로고    scopus 로고
    • Specialized microbial metabolites: functions and origins
    • Davies, J. (2013) Specialized microbial metabolites: functions and origins. J Antibiot 66: 361-364.
    • (2013) J Antibiot , vol.66 , pp. 361-364
    • Davies, J.1
  • 22
    • 84857589768 scopus 로고    scopus 로고
    • Introducing the parvome: bioactive compounds in the microbial world
    • Davies, J., and Ryan, K.S. (2012) Introducing the parvome: bioactive compounds in the microbial world. ACS Chem Biol 7: 252-259.
    • (2012) ACS Chem Biol , vol.7 , pp. 252-259
    • Davies, J.1    Ryan, K.S.2
  • 23
    • 84895074954 scopus 로고    scopus 로고
    • Importance of microbial natural products and the need to revitalize their discovery
    • 2013 Aug 30.
    • Demain, A.L. (2014) Importance of microbial natural products and the need to revitalize their discovery. J Ind Microbiol Biotechnol 41: 185-201. 2013 Aug 30.
    • (2014) J Ind Microbiol Biotechnol , vol.41 , pp. 185-201
    • Demain, A.L.1
  • 26
    • 34848911303 scopus 로고    scopus 로고
    • Polyketide synthases and nonribosomal peptide synthetases: the emerging view from bacterial genomics
    • Donadio, S., Monciardini, P., and Sosio, M. (2007) Polyketide synthases and nonribosomal peptide synthetases: the emerging view from bacterial genomics. Nat Prod Rep 24: 1073-1109.
    • (2007) Nat Prod Rep , vol.24 , pp. 1073-1109
    • Donadio, S.1    Monciardini, P.2    Sosio, M.3
  • 27
    • 64249123522 scopus 로고    scopus 로고
    • Approaches to discovering novel antibacterial and antifungal agents
    • Donadio, S., Monciardini, P., and Sosio, M. (2009) Approaches to discovering novel antibacterial and antifungal agents. Methods Enzymol 438: 3-28.
    • (2009) Methods Enzymol , vol.438 , pp. 3-28
    • Donadio, S.1    Monciardini, P.2    Sosio, M.3
  • 29
    • 33751100882 scopus 로고    scopus 로고
    • Developing a new resource for drug discovery: marine actinomycete bacteria
    • Fenical, W., and Jensen, P.R. (2006) Developing a new resource for drug discovery: marine actinomycete bacteria. Nat Chem Biol 2: 666-673.
    • (2006) Nat Chem Biol , vol.2 , pp. 666-673
    • Fenical, W.1    Jensen, P.R.2
  • 30
  • 31
    • 69549111337 scopus 로고    scopus 로고
    • Antibiotics for emerging pathogens
    • Fischbach, M.A., and Walsh, C.T. (2009) Antibiotics for emerging pathogens. Science 325: 1089-1093.
    • (2009) Science , vol.325 , pp. 1089-1093
    • Fischbach, M.A.1    Walsh, C.T.2
  • 32
    • 0347766000 scopus 로고    scopus 로고
    • Identification of antibiotic stress-inducible promoters: a systematic approach to novel pathway-specific reporter assays for antibacterial drug discovery
    • Fischer, H.P., Brunner, N.A., Wieland, B., Paquette, J., Macko, L., Ziegelbauer, K., and Freiberg, C. (2004) Identification of antibiotic stress-inducible promoters: a systematic approach to novel pathway-specific reporter assays for antibacterial drug discovery. Genome Res 14: 90-98.
    • (2004) Genome Res , vol.14 , pp. 90-98
    • Fischer, H.P.1    Brunner, N.A.2    Wieland, B.3    Paquette, J.4    Macko, L.5    Ziegelbauer, K.6    Freiberg, C.7
  • 34
    • 84893507957 scopus 로고    scopus 로고
    • Heterologous expression of natural product biosynthetic gene clusters in Streptomyces coelicolor: from genome mining to manipulation of biosynthetic pathways
    • Gomez-Escribano, J.P., and Bibb, M.J. (2014) Heterologous expression of natural product biosynthetic gene clusters in Streptomyces coelicolor: from genome mining to manipulation of biosynthetic pathways. J Ind Microbiol Biotechnol 41: 425-431.
    • (2014) J Ind Microbiol Biotechnol , vol.41 , pp. 425-431
    • Gomez-Escribano, J.P.1    Bibb, M.J.2
  • 35
    • 33846294440 scopus 로고    scopus 로고
    • The genomisotopic approach: a systematic method to isolate products of orphan biosynthetic gene clusters
    • Gross, H., Stockwell, V.O., Henkels, M.D., Nowak-Thompson, B., Loper, J.E., and Gerwick, W.H. (2007) The genomisotopic approach: a systematic method to isolate products of orphan biosynthetic gene clusters. Chem Biol 14: 53-63.
    • (2007) Chem Biol , vol.14 , pp. 53-63
    • Gross, H.1    Stockwell, V.O.2    Henkels, M.D.3    Nowak-Thompson, B.4    Loper, J.E.5    Gerwick, W.H.6
  • 37
    • 78650160464 scopus 로고    scopus 로고
    • Salinosporamide natural products: potent 20S proteasome inhibitors as promising cancer chemotherapeutics
    • Gulder, T.A., and Moore, B.S. (2010) Salinosporamide natural products: potent 20S proteasome inhibitors as promising cancer chemotherapeutics. Angew Chem Int Ed Engl 49: 9346-9367.
    • (2010) Angew Chem Int Ed Engl , vol.49 , pp. 9346-9367
    • Gulder, T.A.1    Moore, B.S.2
  • 38
    • 84896737390 scopus 로고    scopus 로고
    • A glycosylated, labionin-containing lanthipeptide with marked antinociceptive activity
    • Iorio, M., Sasso, O., Maffioli, S.I., Bertorelli, R., Monciardini, P., Sosio, M., etal. (2014) A glycosylated, labionin-containing lanthipeptide with marked antinociceptive activity. ACS Chem Biol 9: 398-404.
    • (2014) ACS Chem Biol , vol.9 , pp. 398-404
    • Iorio, M.1    Sasso, O.2    Maffioli, S.I.3    Bertorelli, R.4    Monciardini, P.5    Sosio, M.6
  • 39
    • 77950471293 scopus 로고    scopus 로고
    • Strategies for the isolation and characterization of antibacterial lantibiotics
    • Jabés, D., and Donadio, S. (2010) Strategies for the isolation and characterization of antibacterial lantibiotics. Methods Mol Biol 618: 31-45.
    • (2010) Methods Mol Biol , vol.618 , pp. 31-45
    • Jabés, D.1    Donadio, S.2
  • 40
    • 79953242162 scopus 로고    scopus 로고
    • Efficacy of the new lantibiotic NAI-107 in experimental infections induced by multidrug-resistant Gram-positive pathogens
    • Jabés, D., Brunati, C., Candiani, G., Riva, S., Romanó, G., and Donadio, S. (2011) Efficacy of the new lantibiotic NAI-107 in experimental infections induced by multidrug-resistant Gram-positive pathogens. Antimicrob Agents Chemother 55: 1671-1676.
    • (2011) Antimicrob Agents Chemother , vol.55 , pp. 1671-1676
    • Jabés, D.1    Brunati, C.2    Candiani, G.3    Riva, S.4    Romanó, G.5    Donadio, S.6
  • 41
    • 33644964280 scopus 로고    scopus 로고
    • Discovery of a new source of rifamycin antibiotics in marine sponge actinobacteria by phylogenetic prediction
    • Kim, T.K., Hewavitharana, A.K., Shaw, P.N., and Fuerst, J.A. (2006) Discovery of a new source of rifamycin antibiotics in marine sponge actinobacteria by phylogenetic prediction. Appl Environ Microbiol 72: 2118-2125.
    • (2006) Appl Environ Microbiol , vol.72 , pp. 2118-2125
    • Kim, T.K.1    Hewavitharana, A.K.2    Shaw, P.N.3    Fuerst, J.A.4
  • 42
    • 47249133844 scopus 로고    scopus 로고
    • Forty years of antibiotic discovery at Lepetit: a personal journey
    • Lancini, G. (2006) Forty years of antibiotic discovery at Lepetit: a personal journey. SIM News 56: 192-212.
    • (2006) SIM News , vol.56 , pp. 192-212
    • Lancini, G.1
  • 43
    • 79954997859 scopus 로고    scopus 로고
    • Identification of a bioactive 51-membered macrolide complex by activation of a silent polyketide synthase in Streptomyces ambofaciens
    • Laureti, L., Song, L., Huangm, S., Correm, C., Leblond, P., Challis, G.L., and Aigle, B. (2011) Identification of a bioactive 51-membered macrolide complex by activation of a silent polyketide synthase in Streptomyces ambofaciens. Proc Natl Acad Sci USA 108: 6258-6263.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 6258-6263
    • Laureti, L.1    Song, L.2    Huangm, S.3    Correm, C.4    Leblond, P.5    Challis, G.L.6    Aigle, B.7
  • 44
    • 27544477567 scopus 로고    scopus 로고
    • Discovery of a new peptide natural product by Streptomyces coelicolor genome mining
    • Lautru, S., Deeth, R.J., Bailey, L.M., and Challis, G.L. (2005) Discovery of a new peptide natural product by Streptomyces coelicolor genome mining. Nat Chem Biol 1: 265-269.
    • (2005) Nat Chem Biol , vol.1 , pp. 265-269
    • Lautru, S.1    Deeth, R.J.2    Bailey, L.M.3    Challis, G.L.4
  • 45
    • 0034449443 scopus 로고    scopus 로고
    • Rare genera of actinomycetes as potential producers of new antibiotics
    • Lazzarini, A., Cavaletti, L., Toppo, G., and Marinelli, F. (2000) Rare genera of actinomycetes as potential producers of new antibiotics. Antonie Van Leeuwenhoek 79: 399-405.
    • (2000) Antonie Van Leeuwenhoek , vol.79 , pp. 399-405
    • Lazzarini, A.1    Cavaletti, L.2    Toppo, G.3    Marinelli, F.4
  • 46
    • 84874051724 scopus 로고    scopus 로고
    • A genomic approach to the cryptic secondary metabolome of the anaerobic world
    • Letzel, A.C., Pidot, S.J., and Hertweck, C. (2013) A genomic approach to the cryptic secondary metabolome of the anaerobic world. Nat Prod Rep 30: 392-428.
    • (2013) Nat Prod Rep , vol.30 , pp. 392-428
    • Letzel, A.C.1    Pidot, S.J.2    Hertweck, C.3
  • 47
    • 17844407663 scopus 로고    scopus 로고
    • Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example
    • McAlpine, J.B., Bachmann, B.O., Piraee, M., Tremblay, S., Alarco, A.M., Zazopoulos, E., and Farnet, C.M. (2005) Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example. J Nat Prod 68: 493-496.
    • (2005) J Nat Prod , vol.68 , pp. 493-496
    • McAlpine, J.B.1    Bachmann, B.O.2    Piraee, M.3    Tremblay, S.4    Alarco, A.M.5    Zazopoulos, E.6    Farnet, C.M.7
  • 49
    • 84884668018 scopus 로고    scopus 로고
    • Orthoformimycin, a selective inhibitor of bacterial translation elongation from Streptomyces containing an unusual orthoformate
    • Maffioli, S.I., Fabbretti, A., Brandi, L., Savelsbergh, A., Monciardini, P., Abbondi, M., etal. (2013) Orthoformimycin, a selective inhibitor of bacterial translation elongation from Streptomyces containing an unusual orthoformate. ACS Chem Biol 8: 1939-1946.
    • (2013) ACS Chem Biol , vol.8 , pp. 1939-1946
    • Maffioli, S.I.1    Fabbretti, A.2    Brandi, L.3    Savelsbergh, A.4    Monciardini, P.5    Abbondi, M.6
  • 51
    • 78651517511 scopus 로고    scopus 로고
    • Exploiting plug-and-play synthetic biology for drug discovery and production in microorganisms
    • Medema, M.H., Breitling, R., Bovenberg, R., and Takano, E. (2011) Exploiting plug-and-play synthetic biology for drug discovery and production in microorganisms. Nat Rev Microbiol 9: 131-137.
    • (2011) Nat Rev Microbiol , vol.9 , pp. 131-137
    • Medema, M.H.1    Breitling, R.2    Bovenberg, R.3    Takano, E.4
  • 53
    • 70450236998 scopus 로고    scopus 로고
    • Two novel members of the family Micromonosporaceae, Rugosimonospora acidiphila gen. nov, sp. nov. and Rugosimonospora africana sp. nov
    • Monciardini, P., Cavaletti, L., Ranghetti, A., Schumann, P., Rohde, M., Bamonte, R., etal. (2009) Two novel members of the family Micromonosporaceae, Rugosimonospora acidiphila gen. nov, sp. nov. and Rugosimonospora africana sp. nov. Int J Syst Evol Microbiol 59: 2752-2758.
    • (2009) Int J Syst Evol Microbiol , vol.59 , pp. 2752-2758
    • Monciardini, P.1    Cavaletti, L.2    Ranghetti, A.3    Schumann, P.4    Rohde, M.5    Bamonte, R.6
  • 54
    • 84858308226 scopus 로고    scopus 로고
    • Natural products as sources of new drugs over the 30 years from 1981 to 2010
    • Newman, D.J., and Cragg, G.M. (2012) Natural products as sources of new drugs over the 30 years from 1981 to 2010. J Nat Prod 75: 311-335.
    • (2012) J Nat Prod , vol.75 , pp. 311-335
    • Newman, D.J.1    Cragg, G.M.2
  • 55
    • 33646463757 scopus 로고    scopus 로고
    • Cyanosporasides A and B, chloro- and cyano-cyclopenta[a]indene glycosides from the marine actinomycete 'Salinispora pacifica'
    • Oh, D.C., Williams, P.G., Kauffman, C.A., Jensen, P.R., and Fenical, W. (2006) Cyanosporasides A and B, chloro- and cyano-cyclopenta[a]indene glycosides from the marine actinomycete 'Salinispora pacifica'. Org Lett 8: 1021-1024.
    • (2006) Org Lett , vol.8 , pp. 1021-1024
    • Oh, D.C.1    Williams, P.G.2    Kauffman, C.A.3    Jensen, P.R.4    Fenical, W.5
  • 56
    • 61449113023 scopus 로고    scopus 로고
    • Metabolites from symbiotic bacteria
    • Piel, J. (2009) Metabolites from symbiotic bacteria. Nat Prod Rep 26: 338-362.
    • (2009) Nat Prod Rep , vol.26 , pp. 338-362
    • Piel, J.1
  • 57
    • 80053243567 scopus 로고    scopus 로고
    • Approaches to capturing and designing biologically active small molecules produced by uncultured microbes
    • Piel, J. (2011) Approaches to capturing and designing biologically active small molecules produced by uncultured microbes. Annu Rev Microbiol 65: 431-453.
    • (2011) Annu Rev Microbiol , vol.65 , pp. 431-453
    • Piel, J.1
  • 59
    • 0141818929 scopus 로고    scopus 로고
    • Large-scale essential gene identification in Candida albicans and applications to antifungal drug discovery
    • Roemer, T., Jiang, B., Davison, J., Ketela, T., Veillette, K., Breton, A., etal. (2003) Large-scale essential gene identification in Candida albicans and applications to antifungal drug discovery. Mol Microbiol 50: 167-181.
    • (2003) Mol Microbiol , vol.50 , pp. 167-181
    • Roemer, T.1    Jiang, B.2    Davison, J.3    Ketela, T.4    Veillette, K.5    Breton, A.6
  • 60
    • 84874627513 scopus 로고    scopus 로고
    • Isolation and characterization of NAI-802, a new lantibiotic produced by two different Actinoplanes strains
    • Simone, M., Monciardini, P., Gaspari, E., Donadio, S., and Maffioli, S.I. (2013) Isolation and characterization of NAI-802, a new lantibiotic produced by two different Actinoplanes strains. J Antibiot 66: 73-78.
    • (2013) J Antibiot , vol.66 , pp. 73-78
    • Simone, M.1    Monciardini, P.2    Gaspari, E.3    Donadio, S.4    Maffioli, S.I.5
  • 61
    • 33947313918 scopus 로고    scopus 로고
    • Highly sensitive target-based whole-cell antibacterial discovery strategy by antisense RNA silencing
    • Singh, S.B., Phillips, J.W., and Wang, J. (2007) Highly sensitive target-based whole-cell antibacterial discovery strategy by antisense RNA silencing. Curr Opin Drug Discov Devel 10: 160-166.
    • (2007) Curr Opin Drug Discov Devel , vol.10 , pp. 160-166
    • Singh, S.B.1    Phillips, J.W.2    Wang, J.3
  • 62
    • 65249182567 scopus 로고    scopus 로고
    • Isolation, structure, and antibacterial activities of lucensimycins D-G, discovered from Streptomyces lucensis MA7349 using an antisense strategy
    • Singh, S.B., Zink, D.L., Dorso, K., Motyl, M., Salazar, O., Basilio, A., etal. (2009) Isolation, structure, and antibacterial activities of lucensimycins D-G, discovered from Streptomyces lucensis MA7349 using an antisense strategy. J Nat Prod 72: 345-352.
    • (2009) J Nat Prod , vol.72 , pp. 345-352
    • Singh, S.B.1    Zink, D.L.2    Dorso, K.3    Motyl, M.4    Salazar, O.5    Basilio, A.6
  • 63
    • 70349311733 scopus 로고    scopus 로고
    • Transfer of Actinomadura spadix Nonomura and Ohara 1971 to Actinoallomurus spadix gen. nov., comb. nov.
    • description of Actinoallomurus amamiensis sp. nov., Actinoallomurus caesius sp. nov., Actinoallomurus coprocola sp. nov., Actinoallomurus fulvus sp. nov., Actinoallomurus iriomotensis sp. nov., Actinoallomurus luridus sp. nov., Actinoallomurus purpureus sp. nov. and Actinoallomurus yoronensis sp. nov
    • Tamura, T., Ishida, Y., Nozawa, Y., Otoguro, M., and Suzuki, K. (2009) Transfer of Actinomadura spadix Nonomura and Ohara 1971 to Actinoallomurus spadix gen. nov., comb. nov., and description of Actinoallomurus amamiensis sp. nov., Actinoallomurus caesius sp. nov., Actinoallomurus coprocola sp. nov., Actinoallomurus fulvus sp. nov., Actinoallomurus iriomotensis sp. nov., Actinoallomurus luridus sp. nov., Actinoallomurus purpureus sp. nov. and Actinoallomurus yoronensis sp. nov. Int J Syst Evol Microbiol 59: 1867-1874.
    • (2009) Int J Syst Evol Microbiol , vol.59 , pp. 1867-1874
    • Tamura, T.1    Ishida, Y.2    Nozawa, Y.3    Otoguro, M.4    Suzuki, K.5
  • 65
    • 84934440557 scopus 로고    scopus 로고
    • High-throughput fractionation of natural products for drug discovery
    • Tu, Y., and Yan, B. (2012) High-throughput fractionation of natural products for drug discovery. Methods Mol Biol 918: 117-126.
    • (2012) Methods Mol Biol , vol.918 , pp. 117-126
    • Tu, Y.1    Yan, B.2
  • 67
    • 84868094646 scopus 로고    scopus 로고
    • Biosynthesis of the class III lantipeptide catenulipeptin
    • Wang, H., and van der Donk, W.A. (2012) Biosynthesis of the class III lantipeptide catenulipeptin. ACS Chem Biol 7: 1529-1535.
    • (2012) ACS Chem Biol , vol.7 , pp. 1529-1535
    • Wang, H.1    van der Donk, W.A.2
  • 68
    • 33744994317 scopus 로고    scopus 로고
    • Platensimycin is a selective FabF inhibitor with potent antibiotic properties
    • Wang, J., Soisson, S.M., Young, K., Shoop, W., Kodali, S., Galgoci, A., etal. (2006) Platensimycin is a selective FabF inhibitor with potent antibiotic properties. Nature 441: 358-361.
    • (2006) Nature , vol.441 , pp. 358-361
    • Wang, J.1    Soisson, S.M.2    Young, K.3    Shoop, W.4    Kodali, S.5    Galgoci, A.6
  • 69
    • 70350223819 scopus 로고    scopus 로고
    • The impact of genomics on the exploitation of the myxobacterial secondary metabolome
    • Wenzel, S.C., and Müller, R. (2009) The impact of genomics on the exploitation of the myxobacterial secondary metabolome. Nat Prod Rep 26: 1385-1407.
    • (2009) Nat Prod Rep , vol.26 , pp. 1385-1407
    • Wenzel, S.C.1    Müller, R.2
  • 70
    • 0037318402 scopus 로고    scopus 로고
    • A genomics-guided approach for discovering and expressing cryptic metabolic pathways
    • Zazopoulos, E., Huang, K., Staffa, A., Liu, W., Bachmann, B.O., Nonaka, K., etal. (2003) A genomics-guided approach for discovering and expressing cryptic metabolic pathways. Nat Biotechnol 21: 187-190.
    • (2003) Nat Biotechnol , vol.21 , pp. 187-190
    • Zazopoulos, E.1    Huang, K.2    Staffa, A.3    Liu, W.4    Bachmann, B.O.5    Nonaka, K.6
  • 72
    • 51749111836 scopus 로고    scopus 로고
    • Isolation, structure, and antibacterial activity of philipimycin, a thiazolyl peptide discovered from Actinoplanes philippinensis MA7347
    • Zhang, C., Occi, J., Masurekar, P., Barrett, J.F., Zink, D.L., Smith, S., etal. (2008) Isolation, structure, and antibacterial activity of philipimycin, a thiazolyl peptide discovered from Actinoplanes philippinensis MA7347. J Am Chem Soc 130: 12102-12110.
    • (2008) J Am Chem Soc , vol.130 , pp. 12102-12110
    • Zhang, C.1    Occi, J.2    Masurekar, P.3    Barrett, J.F.4    Zink, D.L.5    Smith, S.6


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