Labyrinthopeptins: A new class of carbacyclic lantibiotics

Angewandte Chemie - International Edition

Volumn 49, Issue 6, 2010, Pages 1151-1154

  Meindl, Kathrin ^b   Schmiederer, Timo ^a   Schneider, Kathrin ^a   Reicke, Andreas ^a   Butz, Diane ^a   Keller, Simone ^a   Gühring, Hans ^c   Vértesy, László ^d   Wink, Joachim ^d   Hoffmann, Holger ^d   Brönstrup, Mark ^d   Sheldrick, George M ^b   Süssmuth, Roderich D ^a  

^a TECHNISCHE UNIVERSITÄT BERLIN   (Germany)

^b UNIVERSITY OF GÖTTINGEN   (Germany)

^c MERCK KGAA   (Germany)

^d SANOFI AVENTIS DEUTSCHLAND GMBH   (Germany)

Author keywords

Antibiotics; Antipain activity; Lanthionine; Lantibiotics, peptides

Indexed keywords

BIOSYNTHETIC GENE CLUSTER; CHEMICAL EQUATIONS; IN-VIVO; LANTHIONINE; LANTHIONINES; LANTIBIOTICS; LANTIBIOTICS, PEPTIDES; MODIFIED AMINO ACIDS; MOUSE MODELS; NEUROPATHIC PAIN;

AMINO ACIDS; ANTIBIOTICS; CHEMICAL REACTIONS; ORGANIC ACIDS;

PEPTIDES;

BACTERIOCIN;

AMINO ACID SEQUENCE; ARTICLE; BIOSYNTHESIS; CHEMICAL STRUCTURE; CHEMISTRY; GENETICS; METABOLISM; MOLECULAR GENETICS; MULTIGENE FAMILY; NUCLEOTIDE SEQUENCE; PROTEIN TERTIARY STRUCTURE; STREPTOMYCES COELICOLOR;

AMINO ACID SEQUENCE; BACTERIOCINS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MULTIGENE FAMILY; PROTEIN STRUCTURE, TERTIARY; STREPTOMYCES COELICOLOR;

EID: 76249088835     PISSN: 14337851     EISSN: 15213773     Source Type: Journal    
DOI: 10.1002/anie.200905773     Document Type: Article

References (25)

1. C. Chatterjee, M. Paul, L. Xie, W. A. van der Donk, Chem. Rev. 2005, 105, 633-683.
2. J. M. Willey, W. A. van der Donk, Annu. Rev. Microbiol. 2007, 61, 477-501.
3. F. J. Van De Ven, G. Jung, Antonie van Leeuwenhoek 1996, 69, 99-107.
4. S.-T. D. Hsu, E. Breukink, G. Bierbaum, H.-G. Sahl, B. de Kruijff, R. Kaptein, N. A. J. van Nuland, A. M. J. J. Bonvin, J. Biol. Chem. 2003, 278, 13110-13117.
5. E. Breukink, I. Wiedemann, C. van Kraaij, O. P. Kuipers, H.-G. Sahl, B. de Kruijff, Science 1999, 286, 2361-2364.
6. P. D. Cotter, C. Hill, R. P. Ross, Nat. Rev. Microbiol. 2005, 5, 777-788.
7. R. Kellner, G. Jung, T. Hörner, H. Zähner, N. Schnell, K.-D. Entian, F. Götz, Eur. J. Biochem. 1988, 177, 53-59.
8. F. Märki, E. Hanni, A. Fredenhagen, J. van Oostrum, Biochem. Pharmacol. 1991, 42, 2027-2035.
9. K. Wakamatsu, S. Y. Choung, T. Kobayashi, K. Inoue, T. Higashijima, T. Miyazawa, Biochemistry 1990, 29, 113-118.
10. E. Breukink, B. de Kruijff, Nat Rev. Drug Discovery 2006, 5, 321-323.
11. H. Grasemann, F. Stehling, H. Brunar, R. Widmann, T. W. Laliberte, L. Molina, G. Döring, F. Ratjen, Chest 2007, 131, 1461-1466.
12. S. Kodani, M. E. Hudson, M. C. Durrant, M. J. Buttner, J. R. Nodwell, J. M. Willey, Proc. Natl. Acad. Sci. USA 2004, 101, 11448-11453.
13. G. Seibert, L. Vértesy, I. Wink, I. Winkler, R. Süssmuth, G. Sheldrick, K. Meindl, M. Broenstrup, H. Hoffmann, H. Guehring, L. Toti, WO2008/040469.
14. J. Wink, R. M. Kroppenstedt, G. Seibert, E. Stackebrandt, Int. J. Syst. Evol. Microbiol 2003, 53, 721-724.
15. R. Dorenbos, T. Stein, J. Kabel, C. Bruand, A. Bolhuis, S. Bron, W. J. Quax, J. M. van Dij, J. Biol. Chem. 2002, 277, 16682-16688.
16. C. P. Kubicek, M. Komon-Zelazowskaa, E. Sandorb, I. S. Druzhininaa, Chem. Biodiversity 2007, 4, 1068-1082.
17. A. L. Davidson, J. Chen, Annu. Rev. Biochem. 2004, 73, 241-268.
18. I. Decosterd, C. J. Woolf, Pain 2000, 87, 149-158.
19. L. Xie, L. M. Miller, C. Chatterjee, O. Averin, N. L. Kelleher, W. A. van der Donk, Science 2004, 303, 679-682.
20. C. Chatterjee, L. M. Miller, Y. L. Leung, L. Xie, M. Yi, N. L. Kelleher, W. A. van der Donk, J. Am. Chem. Soc. 2005, 127, 15332-15333.
21. D. W. Y. Sah, M. H. Ossipov, F. Porreca, Nat. Rev. Drug Discovery 2003, 2, 460-472.
22. S. P. Park, B. M. Kim, J. Y. Koo, H. Cho, C. H. Lee, M. Kim, H. S. Na, U. Oh, Pain 2008, 137, 208-217.
23. R. J. Lewis, M. L. Garcia, Nat. Rev. Drug Discovery 2003, 2, 790-802.
24. B. M. Olivera, J. Biol. Chem. 2006, 281, 31173-31177.
25. K. Garber, Nat Biotechnol 2005, 23, 399.