메뉴 건너뛰기




Volumn 50, Issue 6, 2015, Pages 614-625

Omega-3 polyunsaturated fatty acids as an angelus custos to rescue patients from NSAID-induced gastroduodenal damage

Author keywords

Gastrointestinal risk; Lipid raft; n 3 polyunsaturated fatty acid; n 3 polyunsaturated fatty acid based nonsteroidal anti inflammatory drug; Nonsteroidal anti inflammatory drug

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 6; ANTIOXIDANT; GLUCOSE REGULATED PROTEIN 78; NONSTEROID ANTIINFLAMMATORY AGENT; OMEGA 3 FATTY ACID; PROTECTIVE AGENT; REACTIVE OXYGEN METABOLITE; X BOX BINDING PROTEIN 1;

EID: 84930756978     PISSN: 09441174     EISSN: 14355922     Source Type: Journal    
DOI: 10.1007/s00535-014-1034-z     Document Type: Review
Times cited : (15)

References (107)
  • 1
    • 84890889182 scopus 로고    scopus 로고
    • Mitigating the cardiovascular and renal effects of NSAIDs
    • PID: 24255997
    • Curiel RV, Katz JD. Mitigating the cardiovascular and renal effects of NSAIDs. Pain Med. 2013;14(Suppl 1):S23–8.
    • (2013) Pain Med , vol.14 , pp. S23-S28
    • Curiel, R.V.1    Katz, J.D.2
  • 2
    • 74449093320 scopus 로고    scopus 로고
    • Nonsteroidal anti-inflammatory drugs: adverse effects and their prevention
    • COI: 1:CAS:528:DC%2BC3cXpslWrug%3D%3D, PID: 18823646
    • Vonkeman HE, van de Laar MA. Nonsteroidal anti-inflammatory drugs: adverse effects and their prevention. Semin Arthritis Rheum. 2010;39(4):294–312.
    • (2010) Semin Arthritis Rheum , vol.39 , Issue.4 , pp. 294-312
    • Vonkeman, H.E.1    van de Laar, M.A.2
  • 4
    • 77952478071 scopus 로고    scopus 로고
    • Strategies to optimize treatment with NSAIDs in patients at risk for gastrointestinal and cardiovascular adverse events
    • COI: 1:CAS:528:DC%2BC3cXosVSnu78%3D, PID: 20435236
    • Scheiman JM, Hindley CE. Strategies to optimize treatment with NSAIDs in patients at risk for gastrointestinal and cardiovascular adverse events. Clin Ther. 2010;32(4):667–77.
    • (2010) Clin Ther , vol.32 , Issue.4 , pp. 667-677
    • Scheiman, J.M.1    Hindley, C.E.2
  • 5
    • 84908884324 scopus 로고    scopus 로고
    • Interaction between Helicobacter pylori infection, nonsteroidal anti-inflammatory drugs and/or low-dose aspirin use: old question new insights
    • PID: 25071338
    • Sostres C, Gargallo CJ, Lanas A. Interaction between Helicobacter pylori infection, nonsteroidal anti-inflammatory drugs and/or low-dose aspirin use: old question new insights. World J Gastroenterol. 2014;20(28):9439–50.
    • (2014) World J Gastroenterol , vol.20 , Issue.28 , pp. 9439-9450
    • Sostres, C.1    Gargallo, C.J.2    Lanas, A.3
  • 6
    • 84880754530 scopus 로고    scopus 로고
    • Nonsteroidal anti-inflammatory drugs and upper and lower gastrointestinal mucosal damage
    • PID: 24267289
    • Sostres C, Gargallo CJ, Lanas A. Nonsteroidal anti-inflammatory drugs and upper and lower gastrointestinal mucosal damage. Arthritis Res Ther. 2013;15(Suppl 3):S3.
    • (2013) Arthritis Res Ther , vol.15 , pp. S3
    • Sostres, C.1    Gargallo, C.J.2    Lanas, A.3
  • 7
    • 80053596796 scopus 로고    scopus 로고
    • Wallace JL, Syer S, Denou E, de Palma G, Vong L, McKnight W, et al. Proton pump inhibitors exacerbate NSAID-induced small intestinal injury by inducing dysbiosis. Gastroenterology. 2011;141(4):1314–22.e5.
    • Wallace JL, Syer S, Denou E, de Palma G, Vong L, McKnight W, et al. Proton pump inhibitors exacerbate NSAID-induced small intestinal injury by inducing dysbiosis. Gastroenterology. 2011;141(4):1314–22.e5.
  • 8
    • 41349090797 scopus 로고    scopus 로고
    • The relative efficacies of gastroprotective strategies in chronic users of nonsteroidal anti-inflammatory drugs
    • COI: 1:CAS:528:DC%2BD1cXls1Gmurw%3D, PID: 18294634
    • Targownik LE, Metge CJ, Leung S, Chateau DG. The relative efficacies of gastroprotective strategies in chronic users of nonsteroidal anti-inflammatory drugs. Gastroenterology. 2008;134(4):937–44.
    • (2008) Gastroenterology , vol.134 , Issue.4 , pp. 937-944
    • Targownik, L.E.1    Metge, C.J.2    Leung, S.3    Chateau, D.G.4
  • 9
    • 36249028817 scopus 로고    scopus 로고
    • Gastrointestinal safety of novel nonsteroidal antiinflammatory drugs: selective COX-2 inhibitors and beyond
    • COI: 1:CAS:528:DC%2BD1cXhs1agtr4%3D, PID: 17933277
    • Coruzzi G, Venturi N, Spaggiari S. Gastrointestinal safety of novel nonsteroidal antiinflammatory drugs: selective COX-2 inhibitors and beyond. Acta Biomed. 2007;78(2):96–110.
    • (2007) Acta Biomed , vol.78 , Issue.2 , pp. 96-110
    • Coruzzi, G.1    Venturi, N.2    Spaggiari, S.3
  • 10
    • 0032572548 scopus 로고    scopus 로고
    • Recent considerations in nonsteroidal anti-inflammatory drug gastropathy
    • COI: 1:CAS:528:DyaK1cXlslWkuro%3D, PID: 9715832
    • Singh G. Recent considerations in nonsteroidal anti-inflammatory drug gastropathy. Am J Med. 1998;105(1B):31S–8S.
    • (1998) Am J Med , vol.105 , Issue.1B , pp. 31S-38S
    • Singh, G.1
  • 11
    • 84863868163 scopus 로고    scopus 로고
    • A turbulent decade for NSAIDs: update on current concepts of classification, epidemiology, comparative efficacy, and toxicity
    • COI: 1:CAS:528:DC%2BC38XnvF2nurc%3D, PID: 22193214
    • Conaghan PG. A turbulent decade for NSAIDs: update on current concepts of classification, epidemiology, comparative efficacy, and toxicity. Rheumatol Int. 2012;32(6):1491–502.
    • (2012) Rheumatol Int , vol.32 , Issue.6 , pp. 1491-1502
    • Conaghan, P.G.1
  • 12
    • 0036043074 scopus 로고    scopus 로고
    • Renal effects of nonselective NSAIDs and coxibs
    • PID: 12086295
    • Weir MR. Renal effects of nonselective NSAIDs and coxibs. Cleveland Clin J Med. 2002;69(Suppl 1):SI53–8.
    • (2002) Cleve Clin J Med , vol.69 , pp. SI53-SI58
    • Weir, M.R.1
  • 14
    • 84863091436 scopus 로고    scopus 로고
    • Inhibition of mitochondrial complex I by various non-steroidal anti-inflammatory drugs and its protection by quercetin via a coenzyme Q-like action
    • COI: 1:CAS:528:DC%2BC38XhtVektr7K, PID: 22652335
    • Sandoval-Acuna C, Lopez-Alarcon C, Aliaga ME, Speisky H. Inhibition of mitochondrial complex I by various non-steroidal anti-inflammatory drugs and its protection by quercetin via a coenzyme Q-like action. Chem Biol Interact. 2012;199(1):18–28.
    • (2012) Chem Biol Interact , vol.199 , Issue.1 , pp. 18-28
    • Sandoval-Acuna, C.1    Lopez-Alarcon, C.2    Aliaga, M.E.3    Speisky, H.4
  • 15
    • 52649123285 scopus 로고    scopus 로고
    • Cyclooxygenase 2-selective and nonselective nonsteroidal anti-inflammatory drugs induce oxidative stress by up-regulating vascular NADPH oxidases
    • COI: 1:CAS:528:DC%2BD1cXhtVGqurnI, PID: 18550689
    • Li H, Hortmann M, Daiber A, Oelze M, Ostad MA, Schwarz PM, et al. Cyclooxygenase 2-selective and nonselective nonsteroidal anti-inflammatory drugs induce oxidative stress by up-regulating vascular NADPH oxidases. J Pharmacol Exp Ther. 2008;326(3):745–53.
    • (2008) J Pharmacol Exp Ther , vol.326 , Issue.3 , pp. 745-753
    • Li, H.1    Hortmann, M.2    Daiber, A.3    Oelze, M.4    Ostad, M.A.5    Schwarz, P.M.6
  • 16
    • 33644882540 scopus 로고    scopus 로고
    • Adverse effects of COX-2 inhibitors
    • COI: 1:CAS:528:DC%2BD2MXht1elsrjO
    • Sharma JN, Jawad NM. Adverse effects of COX-2 inhibitors. Sci World J. 2005;5:629–45.
    • (2005) Sci World J , vol.5 , pp. 629-645
    • Sharma, J.N.1    Jawad, N.M.2
  • 17
    • 36248956113 scopus 로고    scopus 로고
    • NSAIDs, coxibs, CINOD and H2S-releasing NSAIDs: what lies beyond the horizon
    • COI: 1:CAS:528:DC%2BD1cXisVOjtL0%3D, PID: 17997373
    • Fiorucci S, Santucci L, Distrutti E. NSAIDs, coxibs, CINOD and H2S-releasing NSAIDs: what lies beyond the horizon. Dig Liver Dis. 2007;39(12):1043–51.
    • (2007) Dig Liver Dis , vol.39 , Issue.12 , pp. 1043-1051
    • Fiorucci, S.1    Santucci, L.2    Distrutti, E.3
  • 18
    • 79952747333 scopus 로고    scopus 로고
    • Hydrogen sulfide-based therapies: focus on H2S releasing NSAIDs
    • COI: 1:CAS:528:DC%2BC3MXktlaktrk%3D, PID: 21275896
    • Fiorucci S, Santucci L. Hydrogen sulfide-based therapies: focus on H2S releasing NSAIDs. Inflamm Allergy Drug Targets. 2011;10(2):133–40.
    • (2011) Inflamm Allergy Drug Targets , vol.10 , Issue.2 , pp. 133-140
    • Fiorucci, S.1    Santucci, L.2
  • 19
    • 0035662474 scopus 로고    scopus 로고
    • Dual acting anti-inflammatory drugs: a reappraisal
    • COI: 1:CAS:528:DC%2BD3MXovFSht7Y%3D, PID: 11735348, (Epub 2001/12/12)
    • Bertolini A, Ottani A, Sandrini M. Dual acting anti-inflammatory drugs: a reappraisal. Pharmacol Res. 2001;44(6):437–50.
    • (2001) Pharmacol Res , vol.44 , Issue.6 , pp. 437-450
    • Bertolini, A.1    Ottani, A.2    Sandrini, M.3
  • 20
    • 33847638037 scopus 로고    scopus 로고
    • Dual acting anti-inflammatory drugs
    • COI: 1:CAS:528:DC%2BD2sXht1Wjsbw%3D, PID: 17305569
    • Leone S, Ottani A, Bertolini A. Dual acting anti-inflammatory drugs. Curr Top Med Chem. 2007;7(3):265–75.
    • (2007) Curr Top Med Chem , vol.7 , Issue.3 , pp. 265-275
    • Leone, S.1    Ottani, A.2    Bertolini, A.3
  • 21
    • 0034949189 scopus 로고    scopus 로고
    • Anti-inflammatory drugs: new multitarget compounds to face an old problem. The dual inhibition concept
    • COI: 1:CAS:528:DC%2BD3MXktFWhtbw%3D, PID: 11394934
    • Celotti F, Laufer S. Anti-inflammatory drugs: new multitarget compounds to face an old problem. The dual inhibition concept. Pharmacol Res. 2001;43(5):429–36.
    • (2001) Pharmacol Res , vol.43 , Issue.5 , pp. 429-436
    • Celotti, F.1    Laufer, S.2
  • 22
    • 84903138797 scopus 로고    scopus 로고
    • Development of GI-safe NSAID; progression from the bark of willow tree to modern pharmacology
    • Kangwan N, Park JM, Hahm KB. Development of GI-safe NSAID; progression from the bark of willow tree to modern pharmacology. Curr Opin Pharmacol. 2014;19C:17–23.
    • (2014) Curr Opin Pharmacol , vol.19C , pp. 17-23
    • Kangwan, N.1    Park, J.M.2    Hahm, K.B.3
  • 23
    • 1142310943 scopus 로고    scopus 로고
    • Transgenic mice: fat-1 mice convert n-6 to n-3 fatty acids
    • COI: 1:CAS:528:DC%2BD2cXpsFWhtA%3D%3D, PID: 14765186
    • Kang JX, Wang J, Wu L, Kang ZB. Transgenic mice: fat-1 mice convert n-6 to n-3 fatty acids. Nature. 2004;427(6974):504.
    • (2004) Nature. , vol.427 , Issue.6974 , pp. 504
    • Kang, J.X.1    Wang, J.2    Wu, L.3    Kang, Z.B.4
  • 24
    • 36649010249 scopus 로고    scopus 로고
    • Fat-1 transgenic mice: a new model for omega-3 research
    • COI: 1:CAS:528:DC%2BD2sXhsVWjtrvE, PID: 18042365
    • Kang JX. Fat-1 transgenic mice: a new model for omega-3 research. Prostaglandins Leukot Essent Fatty Acids. 2007;77(5–6):263–7.
    • (2007) Prostaglandins Leukot Essent Fatty Acids , vol.77 , Issue.5-6 , pp. 263-267
    • Kang, J.X.1
  • 25
    • 84905817898 scopus 로고    scopus 로고
    • Inhibition of endometrial cancer by n-3 polyunsaturated fatty acids in preclinical models
    • COI: 1:CAS:528:DC%2BC2cXhtlSrtb3J
    • Zheng H, Tang H, Liu M, He M, Lai P, Dong H, et al. Inhibition of endometrial cancer by n-3 polyunsaturated fatty acids in preclinical models. Cancer Prev Res (Phila). 2014;7(8):824–34.
    • (2014) Cancer Prev Res (Phila) , vol.7 , Issue.8 , pp. 824-834
    • Zheng, H.1    Tang, H.2    Liu, M.3    He, M.4    Lai, P.5    Dong, H.6
  • 26
    • 79958204979 scopus 로고    scopus 로고
    • Suppressed liver tumorigenesis in fat-1 mice with elevated omega-3 fatty acids is associated with increased omega-3 derived lipid mediators and reduced TNF-α
    • COI: 1:CAS:528:DC%2BC3MXntFClu7g%3D, PID: 21421544
    • Weylandt KH, Krause LF, Gomolka B, Chiu CY, Bilal S, Nadolny A, et al. Suppressed liver tumorigenesis in fat-1 mice with elevated omega-3 fatty acids is associated with increased omega-3 derived lipid mediators and reduced TNF-α. Carcinogenesis. 2011;32(6):897–903.
    • (2011) Carcinogenesis , vol.32 , Issue.6 , pp. 897-903
    • Weylandt, K.H.1    Krause, L.F.2    Gomolka, B.3    Chiu, C.Y.4    Bilal, S.5    Nadolny, A.6
  • 27
    • 33747620742 scopus 로고    scopus 로고
    • Melanoma growth is reduced in fat-1 transgenic mice: impact of omega-6/omega-3 essential fatty acids
    • COI: 1:CAS:528:DC%2BD28Xos1Onsrk%3D, PID: 16888035
    • Xia S, Lu Y, Wang J, He C, Hong S, Serhan CN, et al. Melanoma growth is reduced in fat-1 transgenic mice: impact of omega-6/omega-3 essential fatty acids. Proc Natl Acad Sci U S A. 2006;103(33):12499–504.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , Issue.33 , pp. 12499-12504
    • Xia, S.1    Lu, Y.2    Wang, J.3    He, C.4    Hong, S.5    Serhan, C.N.6
  • 28
    • 84905241884 scopus 로고    scopus 로고
    • Endogenous omega-3 polyunsaturated fatty acid production confers resistance to obesity, dyslipidemia, and diabetes in mice
    • PID: 24978197
    • Li J, Li FR, Wei D, Jia W, Kang JX, Stefanovic-Racic M, et al. Endogenous omega-3 polyunsaturated fatty acid production confers resistance to obesity, dyslipidemia, and diabetes in mice. Mol Endocrinol. 2014;28(8):1316–28.
    • (2014) Mol Endocrinol , vol.28 , Issue.8 , pp. 1316-1328
    • Li, J.1    Li, F.R.2    Wei, D.3    Jia, W.4    Kang, J.X.5    Stefanovic-Racic, M.6
  • 29
    • 79953174254 scopus 로고    scopus 로고
    • High pancreatic n-3 fatty acids prevent STZ-induced diabetes in fat-1 mice: inflammatory pathway inhibition
    • COI: 1:CAS:528:DC%2BC3MXms1WksLc%3D, PID: 21330635
    • Bellenger J, Bellenger S, Bataille A, Massey KA, Nicolaou A, Rialland M, et al. High pancreatic n-3 fatty acids prevent STZ-induced diabetes in fat-1 mice: inflammatory pathway inhibition. Diabetes. 2011;60(4):1090–9.
    • (2011) Diabetes , vol.60 , Issue.4 , pp. 1090-1099
    • Bellenger, J.1    Bellenger, S.2    Bataille, A.3    Massey, K.A.4    Nicolaou, A.5    Rialland, M.6
  • 30
    • 85027954811 scopus 로고    scopus 로고
    • Metabolic enrichment of omega-3 polyunsaturated fatty acids does not reduce the onset of idiopathic knee osteoarthritis in mice
    • COI: 1:STN:280:DC%2BC2cbgvF2qsQ%3D%3D, PID: 25008209
    • Cai A, Hutchison E, Hudson J, Kawashima Y, Komori N, Singh A, et al. Metabolic enrichment of omega-3 polyunsaturated fatty acids does not reduce the onset of idiopathic knee osteoarthritis in mice. Osteoarthritis Cartilage. 2014;22(9):1301–9.
    • (2014) Osteoarthritis Cartilage , vol.22 , Issue.9 , pp. 1301-1309
    • Cai, A.1    Hutchison, E.2    Hudson, J.3    Kawashima, Y.4    Komori, N.5    Singh, A.6
  • 31
    • 84904019789 scopus 로고    scopus 로고
    • Enriched endogenous omega-3 fatty acids in mice protect against global ischemia injury
    • COI: 1:CAS:528:DC%2BC2cXhtVyls7nL, PID: 24875538
    • Luo C, Ren H, Wan JB, Yao X, Zhang X, He C, et al. Enriched endogenous omega-3 fatty acids in mice protect against global ischemia injury. J Lipid Res. 2014;55(7):1288–97.
    • (2014) J Lipid Res , vol.55 , Issue.7 , pp. 1288-1297
    • Luo, C.1    Ren, H.2    Wan, J.B.3    Yao, X.4    Zhang, X.5    He, C.6
  • 32
    • 84887873495 scopus 로고    scopus 로고
    • Transgenic overproduction of omega-3 polyunsaturated fatty acids provides neuroprotection and enhances endogenous neurogenesis after stroke
    • COI: 1:CAS:528:DC%2BC3sXhsFynu7vF, PID: 23971733
    • Hu X, Zhang F, Leak RK, Zhang W, Iwai M, Stetler RA, et al. Transgenic overproduction of omega-3 polyunsaturated fatty acids provides neuroprotection and enhances endogenous neurogenesis after stroke. Curr Mol Med. 2013;13(9):1465–73.
    • (2013) Curr Mol Med , vol.13 , Issue.9 , pp. 1465-1473
    • Hu, X.1    Zhang, F.2    Leak, R.K.3    Zhang, W.4    Iwai, M.5    Stetler, R.A.6
  • 33
    • 84891737631 scopus 로고    scopus 로고
    • Molecular interplay between Δ5/Δ6 desaturases and long-chain fatty acids in the pathogenesis of non-alcoholic steatohepatitis
    • COI: 1:CAS:528:DC%2BC2cXkslart70%3D, PID: 23492103
    • Lopez-Vicario C, Gonzalez-Periz A, Rius B, Moran-Salvador E, Garcia-Alonso V, Lozano JJ, et al. Molecular interplay between Δ5/Δ6 desaturases and long-chain fatty acids in the pathogenesis of non-alcoholic steatohepatitis. Gut. 2014;63(2):344–55.
    • (2014) Gut , vol.63 , Issue.2 , pp. 344-355
    • Lopez-Vicario, C.1    Gonzalez-Periz, A.2    Rius, B.3    Moran-Salvador, E.4    Garcia-Alonso, V.5    Lozano, J.J.6
  • 34
    • 84867892916 scopus 로고    scopus 로고
    • Endogenously synthesized n-3 polyunsaturated fatty acids in fat-1 mice ameliorate high-fat diet-induced non-alcoholic fatty liver disease
    • COI: 1:CAS:528:DC%2BC38XhsVSlurrF, PID: 22981383
    • Kim EH, Bae JS, Hahm KB, Cha JY. Endogenously synthesized n-3 polyunsaturated fatty acids in fat-1 mice ameliorate high-fat diet-induced non-alcoholic fatty liver disease. Biochem Pharmacol. 2012;84(10):1359–65.
    • (2012) Biochem Pharmacol , vol.84 , Issue.10 , pp. 1359-1365
    • Kim, E.H.1    Bae, J.S.2    Hahm, K.B.3    Cha, J.Y.4
  • 35
    • 70949100689 scopus 로고    scopus 로고
    • Omega-3 polyunsaturated fatty acids inhibit hepatocellular carcinoma cell growth through blocking β-catenin and cyclooxygenase-2
    • COI: 1:CAS:528:DC%2BD1MXhtlyrt7%2FN, PID: 19887546
    • Lim K, Han C, Dai Y, Shen M, Wu T. Omega-3 polyunsaturated fatty acids inhibit hepatocellular carcinoma cell growth through blocking β-catenin and cyclooxygenase-2. Mol Cancer Ther. 2009;8(11):3046–55.
    • (2009) Mol Cancer Ther , vol.8 , Issue.11 , pp. 3046-3055
    • Lim, K.1    Han, C.2    Dai, Y.3    Shen, M.4    Wu, T.5
  • 36
    • 4544322635 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress response is involved in nonsteroidal anti-inflammatory drug-induced apoptosis
    • COI: 1:CAS:528:DC%2BD2cXmslWhsb8%3D, PID: 15131590
    • Tsutsumi S, Gotoh T, Tomisato W, Mima S, Hoshino T, Hwang HJ, et al. Endoplasmic reticulum stress response is involved in nonsteroidal anti-inflammatory drug-induced apoptosis. Cell Death Differ. 2004;11(9):1009–16.
    • (2004) Cell Death Differ , vol.11 , Issue.9 , pp. 1009-1016
    • Tsutsumi, S.1    Gotoh, T.2    Tomisato, W.3    Mima, S.4    Hoshino, T.5    Hwang, H.J.6
  • 37
    • 37649005234 scopus 로고    scopus 로고
    • Autophagy in the pathogenesis of disease
    • COI: 1:CAS:528:DC%2BD1cXhtFehtb8%3D, PID: 18191218
    • Levine B, Kroemer G. Autophagy in the pathogenesis of disease. Cell. 2008;132(1):27–42.
    • (2008) Cell , vol.132 , Issue.1 , pp. 27-42
    • Levine, B.1    Kroemer, G.2
  • 38
    • 74849114527 scopus 로고    scopus 로고
    • Cytotoxic effects of celecoxib on Raji lymphoma cells correlate with aggravated endoplasmic reticulum stress but not with inhibition of cyclooxygenase-2
    • COI: 1:CAS:528:DC%2BC3cXhtlGgtLg%3D, PID: 19833390
    • Chen ST, Thomas S, Gaffney KJ, Louie SG, Petasis NA, Schonthal AH. Cytotoxic effects of celecoxib on Raji lymphoma cells correlate with aggravated endoplasmic reticulum stress but not with inhibition of cyclooxygenase-2. Leuk Res. 2010;34(2):250–3.
    • (2010) Leuk Res , vol.34 , Issue.2 , pp. 250-253
    • Chen, S.T.1    Thomas, S.2    Gaffney, K.J.3    Louie, S.G.4    Petasis, N.A.5    Schonthal, A.H.6
  • 40
    • 35348925963 scopus 로고    scopus 로고
    • NSAIDs enhance proteasomic degradation of survivin, a mechanism of gastric epithelial cell injury and apoptosis
    • COI: 1:CAS:528:DC%2BD2sXhtF2msLnE, PID: 17727822
    • Chiou SK, Mandayam S. NSAIDs enhance proteasomic degradation of survivin, a mechanism of gastric epithelial cell injury and apoptosis. Biochem Pharmacol. 2007;74(10):1485–95.
    • (2007) Biochem Pharmacol , vol.74 , Issue.10 , pp. 1485-1495
    • Chiou, S.K.1    Mandayam, S.2
  • 41
    • 84883150831 scopus 로고    scopus 로고
    • The proapoptotic effect of traditional and novel nonsteroidal anti-inflammatory drugs in mammalian and yeast cells
    • PID: 23983899
    • Farrugia G, Balzan R. The proapoptotic effect of traditional and novel nonsteroidal anti-inflammatory drugs in mammalian and yeast cells. Oxid Med Cell Longev. 2013;2013:504230.
    • (2013) Oxid Med Cell Longev , vol.2013 , pp. 504230
    • Farrugia, G.1    Balzan, R.2
  • 42
    • 33745728329 scopus 로고    scopus 로고
    • Lipoxins and new lipid mediators in the resolution of inflammation
    • COI: 1:CAS:528:DC%2BD28XmslGjs7c%3D, PID: 16750421
    • Schwab JM, Serhan CN. Lipoxins and new lipid mediators in the resolution of inflammation. Curr Opin Pharmacol. 2006;6(4):414–20.
    • (2006) Curr Opin Pharmacol , vol.6 , Issue.4 , pp. 414-420
    • Schwab, J.M.1    Serhan, C.N.2
  • 43
    • 27544439792 scopus 로고    scopus 로고
    • The contributions of aspirin and microbial oxygenase to the biosynthesis of anti-inflammatory resolvins: novel oxygenase products from omega-3 polyunsaturated fatty acids
    • COI: 1:CAS:528:DC%2BD2MXhtFylu7fN, PID: 16112645
    • Arita M, Clish CB, Serhan CN. The contributions of aspirin and microbial oxygenase to the biosynthesis of anti-inflammatory resolvins: novel oxygenase products from omega-3 polyunsaturated fatty acids. Biochem Biophys Res Commun. 2005;338(1):149–57.
    • (2005) Biochem Biophys Res Commun , vol.338 , Issue.1 , pp. 149-157
    • Arita, M.1    Clish, C.B.2    Serhan, C.N.3
  • 44
    • 0037152160 scopus 로고    scopus 로고
    • Resolvins: a family of bioactive products of omega-3 fatty acid transformation circuits initiated by aspirin treatment that counter proinflammation signals
    • COI: 1:CAS:528:DC%2BD38XotFGltLc%3D, PID: 12391014
    • Serhan CN, Hong S, Gronert K, Colgan SP, Devchand PR, Mirick G, et al. Resolvins: a family of bioactive products of omega-3 fatty acid transformation circuits initiated by aspirin treatment that counter proinflammation signals. J Exp Med. 2002;196(8):1025–37.
    • (2002) J Exp Med , vol.196 , Issue.8 , pp. 1025-1037
    • Serhan, C.N.1    Hong, S.2    Gronert, K.3    Colgan, S.P.4    Devchand, P.R.5    Mirick, G.6
  • 45
    • 78549283981 scopus 로고    scopus 로고
    • Novel lipid mediators promote resolution of acute inflammation: impact of aspirin and statins
    • COI: 1:CAS:528:DC%2BC3cXhsVWht77J, PID: 21071715
    • Spite M, Serhan CN. Novel lipid mediators promote resolution of acute inflammation: impact of aspirin and statins. Circ Res. 2010;107(10):1170–84.
    • (2010) Circ Res , vol.107 , Issue.10 , pp. 1170-1184
    • Spite, M.1    Serhan, C.N.2
  • 46
    • 34248233132 scopus 로고    scopus 로고
    • Resolvin D1 and its aspirin-triggered 17R epimer. Stereochemical assignments, anti-inflammatory properties, and enzymatic inactivation
    • COI: 1:CAS:528:DC%2BD2sXjtlCisbk%3D, PID: 17244615
    • Sun YP, Oh SF, Uddin J, Yang R, Gotlinger K, Campbell E, et al. Resolvin D1 and its aspirin-triggered 17R epimer. Stereochemical assignments, anti-inflammatory properties, and enzymatic inactivation. J Biol Chem. 2007;282(13):9323–34.
    • (2007) J Biol Chem , vol.282 , Issue.13 , pp. 9323-9334
    • Sun, Y.P.1    Oh, S.F.2    Uddin, J.3    Yang, R.4    Gotlinger, K.5    Campbell, E.6
  • 47
    • 84899853191 scopus 로고    scopus 로고
    • Resolvin D1 reduces ER stress-induced apoptosis and triglyceride accumulation through JNK pathway in HepG2 cells
    • COI: 1:CAS:528:DC%2BC2cXoslCru7w%3D, PID: 24784707
    • Jung TW, Hwang HJ, Hong HC, Choi HY, Yoo HJ, Baik SH, et al. Resolvin D1 reduces ER stress-induced apoptosis and triglyceride accumulation through JNK pathway in HepG2 cells. Mol Cell Endocrinol. 2014;391(1–2):30–40.
    • (2014) Mol Cell Endocrinol , vol.391 , Issue.1-2 , pp. 30-40
    • Jung, T.W.1    Hwang, H.J.2    Hong, H.C.3    Choi, H.Y.4    Yoo, H.J.5    Baik, S.H.6
  • 48
    • 84864304354 scopus 로고    scopus 로고
    • Eicosapentaenoic acid attenuates statin-induced ER stress and toxicity in myoblast
    • COI: 1:CAS:528:DC%2BC38XhtVOlsL3L, PID: 22749998
    • Ohta M, Kawano H, Notsu T, Naba H, Imada K. Eicosapentaenoic acid attenuates statin-induced ER stress and toxicity in myoblast. Biochem Biophys Res Commun. 2012;424(2):301–7.
    • (2012) Biochem Biophys Res Commun. , vol.424 , Issue.2 , pp. 301-307
    • Ohta, M.1    Kawano, H.2    Notsu, T.3    Naba, H.4    Imada, K.5
  • 49
    • 84895469863 scopus 로고    scopus 로고
    • Docosahexaenoic acid reduces ER stress and abnormal protein accumulation and improves neuronal function following traumatic brain injury
    • COI: 1:CAS:528:DC%2BC2cXkt1ajtLg%3D, PID: 24599472
    • Begum G, Yan HQ, Li L, Singh A, Dixon CE, Sun D. Docosahexaenoic acid reduces ER stress and abnormal protein accumulation and improves neuronal function following traumatic brain injury. J Neurosci. 2014;34(10):3743–55.
    • (2014) J Neurosci , vol.34 , Issue.10 , pp. 3743-3755
    • Begum, G.1    Yan, H.Q.2    Li, L.3    Singh, A.4    Dixon, C.E.5    Sun, D.6
  • 50
    • 0024452740 scopus 로고
    • A review of gastric ulcer and gastroduodenal injury in normal volunteers receiving aspirin and other non-steroidal anti-inflammatory drugs
    • COI: 1:STN:280:DyaK3c%2FkvV2hsg%3D%3D, PID: 2683026
    • Lanza FL. A review of gastric ulcer and gastroduodenal injury in normal volunteers receiving aspirin and other non-steroidal anti-inflammatory drugs. Scand J Gastroenterol Suppl. 1989;163:24–31.
    • (1989) Scand J Gastroenterol Suppl , vol.163 , pp. 24-31
    • Lanza, F.L.1
  • 51
    • 0031042347 scopus 로고    scopus 로고
    • Nonsteroidal anti-inflammatory drugs and gastroenteropathy: the second hundred years
    • COI: 1:CAS:528:DyaK2sXhvFOlsLk%3D, PID: 9041264
    • Wallace JL. Nonsteroidal anti-inflammatory drugs and gastroenteropathy: the second hundred years. Gastroenterology. 1997;112(3):1000–16.
    • (1997) Gastroenterology , vol.112 , Issue.3 , pp. 1000-1016
    • Wallace, J.L.1
  • 52
    • 54949089316 scopus 로고    scopus 로고
    • NSAID-induced gastrointestinal damage and the design of GI-sparing NSAIDs
    • COI: 1:CAS:528:DC%2BD1cXhsVOku7bN, PID: 18951293
    • Wallace JL, Vong L. NSAID-induced gastrointestinal damage and the design of GI-sparing NSAIDs. Curr Opin Investig Drugs. 2008;9(11):1151–6.
    • (2008) Curr Opin Investig Drugs , vol.9 , Issue.11 , pp. 1151-1156
    • Wallace, J.L.1    Vong, L.2
  • 53
    • 0024391666 scopus 로고
    • Effects of fish oil on gastric mucosal 6-keto-PGF1 alpha synthesis and ethanol-induced injury
    • COI: 1:CAS:528:DyaL1MXltFChsLs%3D, PID: 2750913
    • Faust T, Redfern JS, Lee E, Feldman M. Effects of fish oil on gastric mucosal 6-keto-PGF1 alpha synthesis and ethanol-induced injury. Am J Physiol. 1989;257(1 Pt 1):G9–13.
    • (1989) Am J Physiol , vol.257 , Issue.1 Pt 1 , pp. G9-G13
    • Faust, T.1    Redfern, J.S.2    Lee, E.3    Feldman, M.4
  • 54
    • 0028295201 scopus 로고
    • Prostaglandins mediate fish oil protection against ethanol-induced gastric mucosal injury in rats
    • COI: 1:CAS:528:DyaK2cXktVSmtLw%3D, PID: 8149856
    • Leung FW. Prostaglandins mediate fish oil protection against ethanol-induced gastric mucosal injury in rats. Dig Dis Sci. 1994;39(4):893.
    • (1994) Dig Dis Sci , vol.39 , Issue.4 , pp. 893
    • Leung, F.W.1
  • 55
    • 0025136810 scopus 로고
    • Effects of aspirin on gastric mucosal prostaglandin E2 and F2 alpha content and on gastric mucosal injury in humans receiving fish oil or olive oil
    • COI: 1:CAS:528:DyaK3cXhsFWmt7Y%3D, PID: 2298365
    • Faust TW, Redfern JS, Podolsky I, Lee E, Grundy SM, Feldman M. Effects of aspirin on gastric mucosal prostaglandin E2 and F2 alpha content and on gastric mucosal injury in humans receiving fish oil or olive oil. Gastroenterology. 1990;98(3):586–91.
    • (1990) Gastroenterology , vol.98 , Issue.3 , pp. 586-591
    • Faust, T.W.1    Redfern, J.S.2    Podolsky, I.3    Lee, E.4    Grundy, S.M.5    Feldman, M.6
  • 56
    • 30544437738 scopus 로고    scopus 로고
    • Effect of fish oil on offensive and defensive factors in gastric ulceration in rats
    • COI: 1:CAS:528:DC%2BD28XksVamtw%3D%3D, PID: 16352428
    • Bhattacharya A, Ghosal S, Bhattacharya SK. Effect of fish oil on offensive and defensive factors in gastric ulceration in rats. Prostaglandins Leukot Essent Fatty Acids. 2006;74(2):109–16.
    • (2006) Prostaglandins Leukot Essent Fatty Acids , vol.74 , Issue.2 , pp. 109-116
    • Bhattacharya, A.1    Ghosal, S.2    Bhattacharya, S.K.3
  • 57
    • 0028789766 scopus 로고
    • Effect of fish oil on indometacin-induced gastric lesions in rats
    • COI: 1:CAS:528:DyaK2MXhtVSmsLnN, PID: 8929233
    • Guzel C, Ulak G, Sermet A, Cicek R, Ulak M. Effect of fish oil on indometacin-induced gastric lesions in rats. Arzneimittelforschung. 1995;45(11):1172–3.
    • (1995) Arzneimittelforschung , vol.45 , Issue.11 , pp. 1172-1173
    • Guzel, C.1    Ulak, G.2    Sermet, A.3    Cicek, R.4    Ulak, M.5
  • 58
    • 0033997261 scopus 로고    scopus 로고
    • Effect of polyunsaturated fatty acids on dexamethasone-induced gastric mucosal damage
    • COI: 1:CAS:528:DC%2BD3cXis12rsrs%3D, PID: 10780873
    • Manjari V, Das UN. Effect of polyunsaturated fatty acids on dexamethasone-induced gastric mucosal damage. Prostaglandins Leukot Essent Fatty Acids. 2000;62(2):85–96.
    • (2000) Prostaglandins Leukot Essent Fatty Acids , vol.62 , Issue.2 , pp. 85-96
    • Manjari, V.1    Das, U.N.2
  • 59
    • 0028882759 scopus 로고
    • Protective effect of fish oil against stress-induced gastric injury in rats
    • COI: 1:CAS:528:DyaK2MXhtVSmsLnO, PID: 8929234
    • Ulak G, Cicek R, Sermet A, Guzel C, Ulak M, Denli O. Protective effect of fish oil against stress-induced gastric injury in rats. Arzneimittelforschung. 1995;45(11):1174–5.
    • (1995) Arzneimittelforschung , vol.45 , Issue.11 , pp. 1174-1175
    • Ulak, G.1    Cicek, R.2    Sermet, A.3    Guzel, C.4    Ulak, M.5    Denli, O.6
  • 60
    • 79952039402 scopus 로고    scopus 로고
    • Docosahexaenoic acid: brain accretion and roles in neuroprotection after brain hypoxia and ischemia
    • COI: 1:CAS:528:DC%2BC3MXhvV2lt7k%3D, PID: 21178607
    • Mayurasakorn K, Williams JJ, Ten VS, Deckelbaum RJ. Docosahexaenoic acid: brain accretion and roles in neuroprotection after brain hypoxia and ischemia. Curr Opin Clin Nutr Metab Care. 2011;14(2):158–67.
    • (2011) Curr Opin Clin Nutr Metab Care , vol.14 , Issue.2 , pp. 158-167
    • Mayurasakorn, K.1    Williams, J.J.2    Ten, V.S.3    Deckelbaum, R.J.4
  • 61
    • 77956063072 scopus 로고    scopus 로고
    • Cardiovascular effects of marine omega-3 fatty acids
    • COI: 1:CAS:528:DC%2BC3cXhtVantr3M, PID: 20638121
    • Saravanan P, Davidson NC, Schmidt EB, Calder PC. Cardiovascular effects of marine omega-3 fatty acids. Lancet. 2010;376(9740):540–50.
    • (2010) Lancet , vol.376 , Issue.9740 , pp. 540-550
    • Saravanan, P.1    Davidson, N.C.2    Schmidt, E.B.3    Calder, P.C.4
  • 62
    • 79551547367 scopus 로고    scopus 로고
    • Oral administration of docosahexaenoic acid attenuates colitis induced by dextran sulfate sodium in mice
    • COI: 1:CAS:528:DC%2BC3MXhsVSkurs%3D, PID: 20824662
    • Cho JY, Chi SG, Chun HS. Oral administration of docosahexaenoic acid attenuates colitis induced by dextran sulfate sodium in mice. Mol Nutr Food Res. 2011;55(2):239–46.
    • (2011) Mol Nutr Food Res , vol.55 , Issue.2 , pp. 239-246
    • Cho, J.Y.1    Chi, S.G.2    Chun, H.S.3
  • 63
    • 0026742483 scopus 로고
    • Indomethacin-induced leukocyte adhesion in mesenteric venules: role of lipoxygenase products
    • COI: 1:CAS:528:DyaK38XksVSjsLc%3D, PID: 1317111
    • Asako H, Kubes P, Wallace J, Gaginella T, Wolf RE, Granger DN. Indomethacin-induced leukocyte adhesion in mesenteric venules: role of lipoxygenase products. Am J Physiol. 1992;262(5 Pt 1):G903–8.
    • (1992) Am J Physiol , vol.262 , Issue.5 Pt 1 , pp. G903-G908
    • Asako, H.1    Kubes, P.2    Wallace, J.3    Gaginella, T.4    Wolf, R.E.5    Granger, D.N.6
  • 64
    • 0028199216 scopus 로고
    • Pentoxifylline prevents indomethacin induced acute gastric mucosal damage in rats: role of tumour necrosis factor alpha
    • COI: 1:CAS:528:DyaK2cXmt1Wmtb8%3D, PID: 8063218
    • Santucci L, Fiorucci S, Giansanti M, Brunori PM, Di Matteo FM, Morelli A. Pentoxifylline prevents indomethacin induced acute gastric mucosal damage in rats: role of tumour necrosis factor alpha. Gut. 1994;35(7):909–15.
    • (1994) Gut , vol.35 , Issue.7 , pp. 909-915
    • Santucci, L.1    Fiorucci, S.2    Giansanti, M.3    Brunori, P.M.4    Di Matteo, F.M.5    Morelli, A.6
  • 65
    • 84869506751 scopus 로고    scopus 로고
    • Docosahexaenoic acid, an omega-3 polyunsaturated acid protects against indomethacin-induced gastric injury
    • COI: 1:CAS:528:DC%2BC38XhsFymt73P, PID: 23063544
    • Pineda-Pena EA, Jimenez-Andrade JM, Castaneda-Hernandez G, Chavez-Pina AE. Docosahexaenoic acid, an omega-3 polyunsaturated acid protects against indomethacin-induced gastric injury. Eur J Pharmacol. 2012;697(1–3):139–43.
    • (2012) Eur J Pharmacol , vol.697 , Issue.1-3 , pp. 139-143
    • Pineda-Pena, E.A.1    Jimenez-Andrade, J.M.2    Castaneda-Hernandez, G.3    Chavez-Pina, A.E.4
  • 66
    • 0036774174 scopus 로고    scopus 로고
    • Polyunsaturated fatty acids and inflammatory diseases
    • COI: 1:CAS:528:DC%2BD38XotVKrur4%3D, PID: 12442911
    • Gil A. Polyunsaturated fatty acids and inflammatory diseases. Biomed Pharmacother. 2002;56(8):388–96.
    • (2002) Biomed Pharmacother , vol.56 , Issue.8 , pp. 388-396
    • Gil, A.1
  • 67
    • 0036931477 scopus 로고    scopus 로고
    • Omega-3 fatty acids in inflammation and autoimmune diseases
    • COI: 1:CAS:528:DC%2BD3sXktleitg%3D%3D, PID: 12480795
    • Simopoulos AP. Omega-3 fatty acids in inflammation and autoimmune diseases. J Am Coll Nutr. 2002;21(6):495–505.
    • (2002) J Am Coll Nutr , vol.21 , Issue.6 , pp. 495-505
    • Simopoulos, A.P.1
  • 68
    • 0142138618 scopus 로고    scopus 로고
    • The metabolism of sulindac enhances its scavenging activity against reactive oxygen and nitrogen species
    • COI: 1:CAS:528:DC%2BD3sXot12jt7o%3D, PID: 14572604
    • Fernandes E, Toste SA, Lima JL, Reis S. The metabolism of sulindac enhances its scavenging activity against reactive oxygen and nitrogen species. Free Radic Biol Med. 2003;35(9):1008–17.
    • (2003) Free Radic Biol Med , vol.35 , Issue.9 , pp. 1008-1017
    • Fernandes, E.1    Toste, S.A.2    Lima, J.L.3    Reis, S.4
  • 69
    • 16244417812 scopus 로고    scopus 로고
    • Hydrogen peroxide scavenging activity by non-steroidal anti-inflammatory drugs
    • COI: 1:CAS:528:DC%2BD2MXivVejur0%3D, PID: 15808884
    • Costa D, Gomes A, Reis S, Lima JL, Fernandes E. Hydrogen peroxide scavenging activity by non-steroidal anti-inflammatory drugs. Life Sci. 2005;76(24):2841–8.
    • (2005) Life Sci , vol.76 , Issue.24 , pp. 2841-2848
    • Costa, D.1    Gomes, A.2    Reis, S.3    Lima, J.L.4    Fernandes, E.5
  • 70
    • 60049096828 scopus 로고    scopus 로고
    • Protective effect of salicylates against hydrogen peroxide stress in yeast
    • COI: 1:CAS:528:DC%2BD1MXjvVKktrk%3D, PID: 19191959
    • Yiannakopoulou E, Tiligada E. Protective effect of salicylates against hydrogen peroxide stress in yeast. J Appl Microbiol. 2009;106(3):903–8.
    • (2009) J Appl Microbiol , vol.106 , Issue.3 , pp. 903-908
    • Yiannakopoulou, E.1    Tiligada, E.2
  • 71
    • 49349100455 scopus 로고    scopus 로고
    • Redox control and oxidative stress in yeast cells
    • COI: 1:CAS:528:DC%2BD1cXhtVarsbfN, PID: 18178164
    • Herrero E, Ros J, Belli G, Cabiscol E. Redox control and oxidative stress in yeast cells. Biochim Biophys Acta. 2008;1780(11):1217–35.
    • (2008) Biochim Biophys Acta , vol.1780 , Issue.11 , pp. 1217-1235
    • Herrero, E.1    Ros, J.2    Belli, G.3    Cabiscol, E.4
  • 72
    • 0037986693 scopus 로고    scopus 로고
    • Salicylate enhances necrosis and apoptosis mediated by the mitochondrial permeability transition
    • COI: 1:CAS:528:DC%2BD3sXjsVKltbw%3D, PID: 12700412
    • Oh KW, Qian T, Brenner DA, Lemasters JJ. Salicylate enhances necrosis and apoptosis mediated by the mitochondrial permeability transition. Toxicol Sci. 2003;73(1):44–52.
    • (2003) Toxicol Sci , vol.73 , Issue.1 , pp. 44-52
    • Oh, K.W.1    Qian, T.2    Brenner, D.A.3    Lemasters, J.J.4
  • 73
    • 26644432066 scopus 로고    scopus 로고
    • Oxidative stress is responsible for mitochondrial permeability transition induction by salicylate in liver mitochondria
    • COI: 1:CAS:528:DC%2BD2MXhtVKisbjF, PID: 16100122
    • Battaglia V, Salvi M, Toninello A. Oxidative stress is responsible for mitochondrial permeability transition induction by salicylate in liver mitochondria. J Biol Chem. 2005;280(40):33864–72.
    • (2005) J Biol Chem , vol.280 , Issue.40 , pp. 33864-33872
    • Battaglia, V.1    Salvi, M.2    Toninello, A.3
  • 74
    • 80052043989 scopus 로고    scopus 로고
    • Acetylsalicylic acid-induced oxidative stress, cell cycle arrest, apoptosis and mitochondrial dysfunction in human hepatoma HepG2 cells
    • COI: 1:CAS:528:DC%2BC3MXhtV2itrbP, PID: 21722632
    • Raza H, John A, Benedict S. Acetylsalicylic acid-induced oxidative stress, cell cycle arrest, apoptosis and mitochondrial dysfunction in human hepatoma HepG2 cells. Eur J Pharmacol. 2011;668(1–2):15–24.
    • (2011) Eur J Pharmacol , vol.668 , Issue.1-2 , pp. 15-24
    • Raza, H.1    John, A.2    Benedict, S.3
  • 75
    • 84891160114 scopus 로고    scopus 로고
    • Long-chain omega 3 fatty acids: molecular bases of potential antioxidant actions
    • COI: 1:CAS:528:DC%2BC3sXhvFOht7%2FF, PID: 24345866
    • Giordano E, Visioli F. Long-chain omega 3 fatty acids: molecular bases of potential antioxidant actions. Prostaglandins Leukot Essent Fatty Acids. 2014;90(1):1–4.
    • (2014) Prostaglandins Leukot Essent Fatty Acids , vol.90 , Issue.1
    • Giordano, E.1    Visioli, F.2
  • 76
    • 84055223546 scopus 로고    scopus 로고
    • Aldehyde stress and up-regulation of Nrf2-mediated antioxidant systems accompany functional adaptations in cardiac mitochondria from mice fed n-3 polyunsaturated fatty acids
    • COI: 1:CAS:528:DC%2BC3MXhs1Cgs7fF, PID: 21880016
    • Anderson EJ, Thayne K, Harris M, Carraway K, Shaikh SR. Aldehyde stress and up-regulation of Nrf2-mediated antioxidant systems accompany functional adaptations in cardiac mitochondria from mice fed n-3 polyunsaturated fatty acids. Biochem J. 2012;441(1):359–66.
    • (2012) Biochem J , vol.441 , Issue.1 , pp. 359-366
    • Anderson, E.J.1    Thayne, K.2    Harris, M.3    Carraway, K.4    Shaikh, S.R.5
  • 77
    • 84907356646 scopus 로고    scopus 로고
    • Do fish oil omega-3 fatty acids enhance antioxidant capacity and mitochondrial fatty acid oxidation in human atrial myocardium via PPARγ activation?
    • COI: 1:CAS:528:DC%2BC2cXhtl2gtbvJ, PID: 24597798
    • Anderson EJ, Thayne KA, Harris M, Shaikh SR, Darden TM, Lark DS, et al. Do fish oil omega-3 fatty acids enhance antioxidant capacity and mitochondrial fatty acid oxidation in human atrial myocardium via PPARγ activation? Antioxid Redox Signal. 2014;21(8):1156–63.
    • (2014) Antioxid Redox Signal , vol.21 , Issue.8 , pp. 1156-1163
    • Anderson, E.J.1    Thayne, K.A.2    Harris, M.3    Shaikh, S.R.4    Darden, T.M.5    Lark, D.S.6
  • 79
    • 0025320409 scopus 로고
    • Dietary n-3 fatty acid supplementation reduces superoxide production and chemiluminescence in a monocyte-enriched preparation of leukocytes
    • COI: 1:CAS:528:DyaK3cXktl2hu7Y%3D, PID: 2159210
    • Fisher M, Levine PH, Weiner BH, Johnson MH, Doyle EM, Ellis PA, et al. Dietary n-3 fatty acid supplementation reduces superoxide production and chemiluminescence in a monocyte-enriched preparation of leukocytes. Am J Clin Nutr. 1990;51(5):804–8.
    • (1990) Am J Clin Nutr. , vol.51 , Issue.5 , pp. 804-808
    • Fisher, M.1    Levine, P.H.2    Weiner, B.H.3    Johnson, M.H.4    Doyle, E.M.5    Ellis, P.A.6
  • 80
    • 33644869928 scopus 로고    scopus 로고
    • Dose-related effects of eicosapentaenoic acid on innate immune function in healthy humans: a comparison of young and older men
    • COI: 1:CAS:528:DC%2BD28Xhs1ehsb4%3D, PID: 16469992
    • Rees D, Miles EA, Banerjee T, Wells SJ, Roynette CE, Wahle KW, et al. Dose-related effects of eicosapentaenoic acid on innate immune function in healthy humans: a comparison of young and older men. Am J Clin Nutr. 2006;83(2):331–42.
    • (2006) Am J Clin Nutr , vol.83 , Issue.2 , pp. 331-342
    • Rees, D.1    Miles, E.A.2    Banerjee, T.3    Wells, S.J.4    Roynette, C.E.5    Wahle, K.W.6
  • 81
    • 84880724830 scopus 로고    scopus 로고
    • 4-Hydroxy hexenal derived from docosahexaenoic acid protects endothelial cells via Nrf2 activation
    • COI: 1:CAS:528:DC%2BC3sXht1eju7vN, PID: 23936010
    • Ishikado A, Morino K, Nishio Y, Nakagawa F, Mukose A, Sono Y, et al. 4-Hydroxy hexenal derived from docosahexaenoic acid protects endothelial cells via Nrf2 activation. PLoS One. 2013;8(7):e69415.
    • (2013) PLoS One , vol.8 , Issue.7 , pp. e69415
    • Ishikado, A.1    Morino, K.2    Nishio, Y.3    Nakagawa, F.4    Mukose, A.5    Sono, Y.6
  • 82
    • 0015511847 scopus 로고
    • Inhibition of prostaglandin synthetase in brain explains the anti-pyretic activity of paracetamol (4-acetamidophenol)
    • COI: 1:CAS:528:DyaE3sXms1ymsA%3D%3D, PID: 4564318
    • Flower RJ, Vane JR. Inhibition of prostaglandin synthetase in brain explains the anti-pyretic activity of paracetamol (4-acetamidophenol). Nature. 1972;240(5381):410–1.
    • (1972) Nature , vol.240 , Issue.5381 , pp. 410-411
    • Flower, R.J.1    Vane, J.R.2
  • 83
    • 0028939954 scopus 로고
    • Non-steroidal anti-inflammatory drugs (NSAIDs) associate with zwitterionic phospholipids: insight into the mechanism and reversal of NSAID-induced gastrointestinal injury
    • COI: 1:CAS:528:DyaK2MXksVeru7w%3D, PID: 7585013
    • Lichtenberger LM, Wang ZM, Romero JJ, Ulloa C, Perez JC, Giraud MN, et al. Non-steroidal anti-inflammatory drugs (NSAIDs) associate with zwitterionic phospholipids: insight into the mechanism and reversal of NSAID-induced gastrointestinal injury. Nat Med. 1995;1(2):154–8.
    • (1995) Nat Med , vol.1 , Issue.2 , pp. 154-158
    • Lichtenberger, L.M.1    Wang, Z.M.2    Romero, J.J.3    Ulloa, C.4    Perez, J.C.5    Giraud, M.N.6
  • 84
    • 65649144271 scopus 로고    scopus 로고
    • The membrane-activity of ibuprofen, diclofenac, and naproxen: a physico-chemical study with lecithin phospholipids
    • PID: 19366589
    • Manrique-Moreno M, Garidel P, Suwalsky M, Howe J, Brandenburg K. The membrane-activity of ibuprofen, diclofenac, and naproxen: a physico-chemical study with lecithin phospholipids. Biochim Biophys Acta. 2009;1788(6):1296–303.
    • (2009) Biochim Biophys Acta , vol.1788 , Issue.6 , pp. 1296-1303
    • Manrique-Moreno, M.1    Garidel, P.2    Suwalsky, M.3    Howe, J.4    Brandenburg, K.5
  • 85
    • 0032937942 scopus 로고    scopus 로고
    • Interaction of indomethacin and naproxen with gastric surface-active phospholipids: a possible mechanism for the gastric toxicity of nonsteroidal anti-inflammatory drugs (NSAIDs)
    • COI: 1:CAS:528:DyaK1MXitV2mtQ%3D%3D, PID: 9890551
    • Giraud MN, Motta C, Romero JJ, Bommelaer G, Lichtenberger LM. Interaction of indomethacin and naproxen with gastric surface-active phospholipids: a possible mechanism for the gastric toxicity of nonsteroidal anti-inflammatory drugs (NSAIDs). Biochem Pharmacol. 1999;57(3):247–54.
    • (1999) Biochem Pharmacol , vol.57 , Issue.3 , pp. 247-254
    • Giraud, M.N.1    Motta, C.2    Romero, J.J.3    Bommelaer, G.4    Lichtenberger, L.M.5
  • 86
    • 33751226593 scopus 로고    scopus 로고
    • NSAID injury to the gastrointestinal tract: evidence that NSAIDs interact with phospholipids to weaken the hydrophobic surface barrier and induce the formation of unstable pores in membranes
    • COI: 1:CAS:528:DC%2BD2sXksVKmsbY%3D, PID: 17132203
    • Lichtenberger LM, Zhou Y, Dial EJ, Raphael RM. NSAID injury to the gastrointestinal tract: evidence that NSAIDs interact with phospholipids to weaken the hydrophobic surface barrier and induce the formation of unstable pores in membranes. J Pharm Pharmacol. 2006;58(11):1421–8.
    • (2006) J Pharm Pharmacol , vol.58 , Issue.11 , pp. 1421-1428
    • Lichtenberger, L.M.1    Zhou, Y.2    Dial, E.J.3    Raphael, R.M.4
  • 87
    • 79959342956 scopus 로고    scopus 로고
    • Synchrotron SAXS and WAXS study of the interactions of NSAIDs with lipid membranes
    • COI: 1:CAS:528:DC%2BC3MXmvFKqt7o%3D, PID: 21598995
    • Nunes C, Brezesinski G, Lima JL, Reis S, Lucio M. Synchrotron SAXS and WAXS study of the interactions of NSAIDs with lipid membranes. J Phys Chem B. 2011;115(24):8024–32.
    • (2011) J Phys Chem B , vol.115 , Issue.24 , pp. 8024-8032
    • Nunes, C.1    Brezesinski, G.2    Lima, J.L.3    Reis, S.4    Lucio, M.5
  • 88
    • 80052202760 scopus 로고    scopus 로고
    • NSAIDs interactions with membranes: a biophysical approach
    • COI: 1:CAS:528:DC%2BC3MXpvVektrc%3D, PID: 21790169
    • Nunes C, Brezesinski G, Pereira-Leite C, Lima JL, Reis S, Lucio M. NSAIDs interactions with membranes: a biophysical approach. Langmuir ACS J Surfaces Colloids. 2011;27(17):10847–58.
    • (2011) Langmuir , vol.27 , Issue.17 , pp. 10847-10858
    • Nunes, C.1    Brezesinski, G.2    Pereira-Leite, C.3    Lima, J.L.4    Reis, S.5    Lucio, M.6
  • 89
    • 0142059080 scopus 로고    scopus 로고
    • Docosahexaenoic acid: membrane properties of a unique fatty acid
    • COI: 1:CAS:528:DC%2BD3sXot1OltL8%3D, PID: 14580707
    • Stillwell W, Wassall SR. Docosahexaenoic acid: membrane properties of a unique fatty acid. Chem Phys Lipids. 2003;126(1):1–27.
    • (2003) Chem Phys Lipids , vol.126 , Issue.1
    • Stillwell, W.1    Wassall, S.R.2
  • 90
    • 7644222841 scopus 로고    scopus 로고
    • Order from disorder, corralling cholesterol with chaotic lipids. The role of polyunsaturated lipids in membrane raft formation
    • COI: 1:CAS:528:DC%2BD2cXpsFSktbg%3D, PID: 15530450
    • Wassall SR, Brzustowicz MR, Shaikh SR, Cherezov V, Caffrey M, Stillwell W. Order from disorder, corralling cholesterol with chaotic lipids. The role of polyunsaturated lipids in membrane raft formation. Chem Phys Lipids. 2004;132(1):79–88.
    • (2004) Chem Phys Lipids , vol.132 , Issue.1 , pp. 79-88
    • Wassall, S.R.1    Brzustowicz, M.R.2    Shaikh, S.R.3    Cherezov, V.4    Caffrey, M.5    Stillwell, W.6
  • 91
    • 56349109532 scopus 로고    scopus 로고
    • Bioactive dietary long-chain fatty acids: emerging mechanisms of action
    • COI: 1:CAS:528:DC%2BD1cXhsV2lsrzF, PID: 18492298
    • Chapkin RS, McMurray DN, Davidson LA, Patil BS, Fan YY, Lupton JR. Bioactive dietary long-chain fatty acids: emerging mechanisms of action. Br J Nutr. 2008;100(6):1152–7.
    • (2008) Br J Nutr , vol.100 , Issue.6 , pp. 1152-1157
    • Chapkin, R.S.1    McMurray, D.N.2    Davidson, L.A.3    Patil, B.S.4    Fan, Y.Y.5    Lupton, J.R.6
  • 92
    • 58749083403 scopus 로고    scopus 로고
    • N-3 polyunsaturated fatty acids suppress the localization and activation of signaling proteins at the immunological synapse in murine CD4+ T cells by affecting lipid raft formation
    • COI: 1:CAS:528:DC%2BD1cXht1KrtrnI, PID: 18941214
    • Kim W, Fan YY, Barhoumi R, Smith R, McMurray DN, Chapkin RS. n-3 polyunsaturated fatty acids suppress the localization and activation of signaling proteins at the immunological synapse in murine CD4+ T cells by affecting lipid raft formation. J Immunol. 2008;181(9):6236–43.
    • (2008) J Immunol , vol.181 , Issue.9 , pp. 6236-6243
    • Kim, W.1    Fan, Y.Y.2    Barhoumi, R.3    Smith, R.4    McMurray, D.N.5    Chapkin, R.S.6
  • 93
    • 69549086431 scopus 로고    scopus 로고
    • Docosahexaenoic acid modifies the clustering and size of lipid rafts and the lateral organization and surface expression of MHC class I of EL4 cells
    • COI: 1:CAS:528:DC%2BD1MXhtlWrt7nO, PID: 19640970
    • Shaikh SR, Rockett BD, Salameh M, Carraway K. Docosahexaenoic acid modifies the clustering and size of lipid rafts and the lateral organization and surface expression of MHC class I of EL4 cells. J Nutr. 2009;139(9):1632–9.
    • (2009) J Nutr. , vol.139 , Issue.9 , pp. 1632-1639
    • Shaikh, S.R.1    Rockett, B.D.2    Salameh, M.3    Carraway, K.4
  • 94
    • 33746085241 scopus 로고    scopus 로고
    • Rafts defined: a report on the keystone symposium on lipid rafts and cell function
    • COI: 1:CAS:528:DC%2BD28XntVChu7w%3D, PID: 16645198
    • Pike LJ. Rafts defined: a report on the keystone symposium on lipid rafts and cell function. J Lipid Res. 2006;47(7):1597–8.
    • (2006) J Lipid Res , vol.47 , Issue.7 , pp. 1597-1598
    • Pike, L.J.1
  • 95
    • 74849118341 scopus 로고    scopus 로고
    • Lipid rafts as a membrane-organizing principle
    • COI: 1:CAS:528:DC%2BD1MXhs1WksrfJ, PID: 20044567
    • Lingwood D, Simons K. Lipid rafts as a membrane-organizing principle. Science. 2010;327(5961):46–50.
    • (2010) Science , vol.327 , Issue.5961 , pp. 46-50
    • Lingwood, D.1    Simons, K.2
  • 96
    • 41949099869 scopus 로고    scopus 로고
    • Dissecting lipid raft facilitated cell signaling pathways in cancer
    • COI: 1:CAS:528:DC%2BD1cXkvFWlur8%3D, PID: 18166162
    • Patra SK. Dissecting lipid raft facilitated cell signaling pathways in cancer. Biochim Biophys Acta. 2008;1785(2):182–206.
    • (2008) Biochim Biophys Acta , vol.1785 , Issue.2 , pp. 182-206
    • Patra, S.K.1
  • 97
    • 79955564023 scopus 로고    scopus 로고
    • Intestinal inflammation and cancer
    • COI: 1:CAS:528:DC%2BC3MXlsVGhsLg%3D, PID: 21530747
    • Ullman TA, Itzkowitz SH. Intestinal inflammation and cancer. Gastroenterology. 2011;140(6):1807–16.
    • (2011) Gastroenterology , vol.140 , Issue.6 , pp. 1807-1816
    • Ullman, T.A.1    Itzkowitz, S.H.2
  • 98
    • 6944240423 scopus 로고    scopus 로고
    • n-3 PUFA alter caveolae lipid composition and resident protein localization in mouse colon
    • COI: 1:CAS:528:DC%2BD2cXkslWhsro%3D, PID: 15084525
    • Ma DW, Seo J, Davidson LA, Callaway ES, Fan YY, Lupton JR, et al. n-3 PUFA alter caveolae lipid composition and resident protein localization in mouse colon. FASEB J. 2004;18(9):1040–2.
    • (2004) FASEB J , vol.18 , Issue.9 , pp. 1040-1042
    • Ma, D.W.1    Seo, J.2    Davidson, L.A.3    Callaway, E.S.4    Fan, Y.Y.5    Lupton, J.R.6
  • 99
    • 84872037810 scopus 로고    scopus 로고
    • Membrane lipid raft organization is uniquely modified by n-3 polyunsaturated fatty acids
    • COI: 1:CAS:528:DC%2BC38XlvVSmsrs%3D, PID: 22515942
    • Turk HF, Chapkin RS. Membrane lipid raft organization is uniquely modified by n-3 polyunsaturated fatty acids. Prostaglandins Leukot Essent Fatty Acids. 2013;88(1):43–7.
    • (2013) Prostaglandins Leukot Essent Fatty Acids , vol.88 , Issue.1 , pp. 43-47
    • Turk, H.F.1    Chapkin, R.S.2
  • 100
    • 8444252896 scopus 로고    scopus 로고
    • Dietary docosahexaenoic acid suppresses T cell protein kinase Cθ lipid raft recruitment and IL-2 production
    • COI: 1:CAS:528:DC%2BD2cXpt1Ols7c%3D, PID: 15528352
    • Fan YY, Ly LH, Barhoumi R, McMurray DN, Chapkin RS. Dietary docosahexaenoic acid suppresses T cell protein kinase Cθ lipid raft recruitment and IL-2 production. J Immunol. 2004;173(10):6151–60.
    • (2004) J Immunol. , vol.173 , Issue.10 , pp. 6151-6160
    • Fan, Y.Y.1    Ly, L.H.2    Barhoumi, R.3    McMurray, D.N.4    Chapkin, R.S.5
  • 101
    • 80052014052 scopus 로고    scopus 로고
    • Inflammation meets cancer, with NF-κB as the matchmaker
    • COI: 1:CAS:528:DC%2BC3MXptV2isrk%3D, PID: 21772280
    • Ben-Neriah Y, Karin M. Inflammation meets cancer, with NF-κB as the matchmaker. Nat Immunol. 2011;12(8):715–23.
    • (2011) Nat Immunol , vol.12 , Issue.8 , pp. 715-723
    • Ben-Neriah, Y.1    Karin, M.2
  • 102
    • 79751528169 scopus 로고    scopus 로고
    • Low-dose aspirin-induced ulceration is attenuated by aspirin-phosphatidylcholine: a randomized clinical trial
    • COI: 1:CAS:528:DC%2BC3MXhsFOnu7c%3D, PID: 21081908
    • Cryer B, Bhatt DL, Lanza FL, Dong JF, Lichtenberger LM, Marathi UK. Low-dose aspirin-induced ulceration is attenuated by aspirin-phosphatidylcholine: a randomized clinical trial. Am J Gastroenterol. 2011;106(2):272–7.
    • (2011) Am J Gastroenterol , vol.106 , Issue.2 , pp. 272-277
    • Cryer, B.1    Bhatt, D.L.2    Lanza, F.L.3    Dong, J.F.4    Lichtenberger, L.M.5    Marathi, U.K.6
  • 103
    • 0033013798 scopus 로고    scopus 로고
    • Phospholipid association reduces the gastric mucosal toxicity of aspirin in human subjects
    • COI: 1:CAS:528:DyaK1MXksFyksLo%3D, PID: 10406241
    • Anand BS, Romero JJ, Sanduja SK, Lichtenberger LM. Phospholipid association reduces the gastric mucosal toxicity of aspirin in human subjects. Am J Gastroenterol. 1999;94(7):1818–22.
    • (1999) Am J Gastroenterol , vol.94 , Issue.7 , pp. 1818-1822
    • Anand, B.S.1    Romero, J.J.2    Sanduja, S.K.3    Lichtenberger, L.M.4
  • 105
    • 79958862928 scopus 로고    scopus 로고
    • Recent developments in the treatment of osteoarthritis with NSAIDs
    • COI: 1:CAS:528:DC%2BC3MXnsFOjsLg%3D, PID: 21561395
    • Argoff CE. Recent developments in the treatment of osteoarthritis with NSAIDs. Curr Med Res Opin. 2011;27(7):1315–27.
    • (2011) Curr Med Res Opin , vol.27 , Issue.7 , pp. 1315-1327
    • Argoff, C.E.1
  • 107
    • 84884351089 scopus 로고    scopus 로고
    • Medlock S, Eslami S, Askari M, Taherzadeh Z, Opondo D, de Rooij SE, et al. Co-prescription of gastroprotective agents and their efficacy in elderly patients taking nonsteroidal anti-inflammatory drugs: a systematic review of observational studies. Clin Gastroenterol Hepatol. 2013;11(10):1259–69.e10.
    • Medlock S, Eslami S, Askari M, Taherzadeh Z, Opondo D, de Rooij SE, et al. Co-prescription of gastroprotective agents and their efficacy in elderly patients taking nonsteroidal anti-inflammatory drugs: a systematic review of observational studies. Clin Gastroenterol Hepatol. 2013;11(10):1259–69.e10.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.