Development of GI-safe NSAID; Progression from the bark of willow tree to modern pharmacology

Current Opinion in Pharmacology

Volumn 19, Issue , 2014, Pages 17-23

  Kangwan, Napapan ^a   Park, Jong Min ^a   Hahm, Ki Baik ^a  

^a CHA University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

CHLOROQUINE; GASTROINTESTINAL MUCOSA PROTECTIVE AGENT; GLUCOSAMINE; ICOSANOID; NONSTEROID ANTIINFLAMMATORY AGENT; PHOSPHATIDYLCHOLINE; PHOSPHOLIPID; POLYUNSATURATED FATTY ACID; POTASSIUM COMPETITIVE ACID BLOCKER; PROBIOTIC AGENT; ANTIINFLAMMATORY AGENT; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; GAS RELEASING NONSTEROID ANTIINFLAMMATORY AGENT; GASTROINTESTINAL AGENT; MUCOSAL PROTECTIVE AGENT; PHOSPHATIDYLCHOLINE NONSTEROID ANTIINFLAMMATORY AGENT; POLYUNSATURATED FATTY ACID MIXED NONSTEROID ANTIINFLAMMATORY AGENT; PROTECTIVE AGENT; S ALLYLCYSTEINE; SURVIVIN; UNCLASSIFIED DRUG;

ARTICLE; AUTOPHAGY; CLINICAL EFFECTIVENESS; DRUG EFFICACY; DRUG MECHANISM; DRUG POTENTIATION; DRUG RESPONSE; DRUG SAFETY; DRUG TOLERABILITY; FLOW RATE; GASTROINTESTINAL MOTILITY; GASTROINTESTINAL SYMPTOM; HUMAN; INTESTINE BLOOD FLOW; INTESTINE MUCOSA PERMEABILITY; LACTOBACILLUS; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; NONHUMAN; OUTCOME ASSESSMENT; OXIDATIVE PHOSPHORYLATION; PRIORITY JOURNAL; STOMACH INJURY; STOMACH PROTECTION; BARK; BIOTECHNOLOGY; CELL INTERACTION; CELL RESTITUTION; CELLULAR, SUBCELLULAR AND MOLECULAR BIOLOGICAL PHENOMENA AND FUNCTIONS; DIGESTIVE SYSTEM INJURY; DRUG DEVELOPMENT; DRUG TOXICITY; ENDOPLASMIC RETICULUM STRESS; EPITHELIUM CELL; GASTRODUODENAL DAMAGE; GASTROINTESTINAL IRRITATION; GASTROINTESTINAL MUCOSA; GASTROINTESTINAL SAFETY; INTESTINE FLORA; LEUKOCYTE ADHERENCE; MEMBRANE BIOLOGY; MEMBRANE PERMEABILITY; MEMBRANE PERMEABILIZATION; MUCOSAL PERMEABILITY; MUCUS BICARBONATE BARRIER; OXIDATIVE PHOSPHORYLATION UNCOUPLING; OXIDATIVE STRESS; PERMEABILITY BARRIER; PROTEIN DEGRADATION; PROTEIN PROCESSING; STOMACH BLOOD FLOW; TRANSCRIPTION REGULATION; WILLOW; ANIMAL; CHEMICALLY INDUCED; DRUG EFFECTS; INTESTINAL DISEASES; STOMACH MUCOSA;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; GASTRIC MUCOSA; HUMANS; INTESTINAL DISEASES; PLANT BARK; PROTECTIVE AGENTS; SALIX;

EID: 84903138797     PISSN: 14714892     EISSN: 14714973     Source Type: Journal    
DOI: 10.1016/j.coph.2014.06.003     Document Type: Review

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