Effect of polyunsaturated fatty acids on dexamethasone - Induced gastric mucosal damage

Prostaglandins Leukotrienes and Essential Fatty Acids

Volumn 62, Issue 2, 2000, Pages 85-96

  Manjari, V ^a   Das, U N ^b  

^a L V PRASAD EYE INSTITUTE   (India)

^b EFA Sciences LLC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIOXIDANT; ARACHIDONIC ACID; CATALASE; DEXAMETHASONE; DOCOSAHEXAENOIC ACID; FAMOTIDINE; FATTY ACID; FISH OIL; FREE RADICAL; GLUTATHIONE PEROXIDASE; HISTAMINE H2 RECEPTOR ANTAGONIST; ICOSAPENTAENOIC ACID; LANSOPRAZOLE; LINOLEIC ACID; LIPID PEROXIDE; NITRIC OXIDE; OMEGA 3 FATTY ACID; POLYUNSATURATED FATTY ACID; PROSTAGLANDIN; PROTON PUMP INHIBITOR; SUPEROXIDE DISMUTASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIETARY INTAKE; DRUG INDUCED DISEASE; MALE; NONHUMAN; PATHOLOGY; PEPTIC ULCER; PRIORITY JOURNAL; RAT; STOMACH MUCOSA LESION; STOMACH ULCER;

ANIMALIA; HELICOBACTER PYLORI; RATTUS NORVEGICUS;

EID: 0033997261     PISSN: 09523278     EISSN: None     Source Type: Journal    
DOI: 10.1054/plef.1999.0125     Document Type: Article

References (42)

1. Friedman J. D., Haile P M., Siegelaaub A. B., Seltzer C. E. Cigarette, alchol coffee and peptic ulcer. N Engl J Med. 290:1974;469-473.
2. Fletcher D. R., Shulkes A., Hardy K. J. The effect of cigarette smoking in the gastric acid secretion and gastric mucosal blood flow in man. Aust N Z J Med. 15:1985;417-420.
3. Doll R., Jones F. A., Pygott F. Effects of smoking on the production and maintenance of gastric and duodenal ulcers. Lancet. 1:1958;657-662.
4. Stulhofer M. Stress ulcer - acute ulcerous erosive lesions in the gastroduodenal mucosa. Acta Chir Iugosl. 27:1980;95-101.
5. Hillman K. Acute stress syndrome. Anaesth Intensive Care. 13:1985;230-240.
6. Knight A., Bihari D., Tinker J. Stress ulcer in critically ill patients. Br J Hosp Med. 33:1985;216-219.
7. Ivey K. J. Drugs gastritis and peptic ulcer. J Clin Gastroenterol. 3:1981;29-34.
8. Lubin R. I., Misbach W. D., Zemke E. M. Acute perforation of DU during ACTH treatment and cortisone therapy. Gasteroenterology. 18:1951;308-312.
9. Meltzer L. E., Bockman A. A., Kanenson W. The incidence of peptic ulcer among patients on long term prednisalone therapy. Gasteroenterology. 35:1958;351-356.
10. Von Berger, Dellinger H. C. Hypergastrinaemia induced by glucocorticoid and corticotropin treatment in man. Dig Dis. 21:1976;376-380.
11. Chung R. S. K., Field M., Silen W. Effects of methyl prednesolone on hydrogen ion absorption in canine stomach. J Clin Invest. 62:1978;262-270.
12. Megraud F., Lamouliatte H. Helicobacter Pylori and duodenal ulcer evidence suggesting causation. Dig Dis Sci. 5:1992;769-772.
13. Davies G. R., Banatvala N., Collins C. E. Relationship between infective load of helicobacter pylori and reactive oxygen metabolite production in antral mucosa. Scand J Gastroenterol. 29:1994;419-424.
14. Hollander D., Tarnawski A. Dietary essential fatty acids and peptic ulcer disease: a hypothesis. Gut. 276:1986;239-242.
15. Peskar B. M. On the synthesis of prostaglandins by human gastric and its modification by drugs. Biochem Biophys Acta. 487:1977;307-314.
16. Das U. N., Reddy D. N., Rao P. N. Essential fatty acids and peptic ulcer disease. Gut. 28:1987;914.
17. Das U. N., Reddy D. N., Rao P. N. Essential fatty acids and peptic ulcer disease. Gut. 29:1988;134.
18. Manjari V., Das U. N. Oxidant stress, anit-oxidants, nitric oxide and essential fatty acids in peptic ulcer disease. Pgs Lks EFAs. 59:1998;401-406.
19. Fraga C. G., Leibovitz B. E., Tappel A. L. Lipid peroxidation measured as thiobarbituric acid reactive substances in tissue slices: characterization and comparison with homogenates and microsomes. Free Rad Biol Med. 4:1988;155-161.
20. Kumar K. V., Das U. N. Are free radicals involved in the pathobiology of human essential hypertension? Free Radical Res Commun. 19:1993;59-66.
21. Lepoivre B., Boudbid H., Petit J. F. Anti-proliferative activity of gamma-interferon combined with lps on murine adenocarcinoma: dependence on an l-arginine metabolism with production of nitrite and citruline. Cancer Research. 49:1989;1970-1979.
22. Das U. N., Krishna Mohan I., Vijay Kumar K., Sravan Kumar G., Chandra Sekhar C. Beneficial effects of l-arginine in non- insulin dependent diabetes mellitus: a potential role for nitric oxide. Med Sci Res. 21:1993;669-670.
23. Mccord J. M., Fridovich I. SOD: an enzyme function for erythrocuprein (hemocuprein). J Biol Chem. 244:1969;6049-6055.
24. Aebi H. Catalase. Packer L. Methods In Enzymology. 1984;121-126 Academic Press, Orlando.
25. Paglia D. E., Valentine W. N. Studirs on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase. J Lab Clin Med. 70:1967;158-169.
26. Huang Y. S., Das U. N., Horrobin D. F. Effect of dexamethasone on the distribution of essential fatty acids in plasma and liver phospholipids. IRCS Med Sci. 14:1986;180-181.
27. Nassar B. A., Das U. N., Huang Y. S., Ells G., Horrobin D. F. The effect of chemical hepatocarcinogenesis on liver phospholipid consumption in rats fed with n-6 and n-3 fatty acid-supplemented diets. Proc Soc Exp Biol Med. 199:1992;365-368.
28. Das U. N. Essential fatty acid metabolism in patients with essential hypertension, diabetes mellitus and coronary heart disease. Prostaglan Leukot Essent Fatty Acids. 52:1995;387-391.
29. Huang Y. S., Drummond R., Horrobin D. F. Protective effect of gamma-linolenic acid on aspirin induced gastric hemorrhage in rats. Digestion. 36:1987;36-41.
30. 2derived free radicals in cysteamine induced in rats. J Formos Med Assoc. 93:1994;11-14.
31. Kedziora-Korratowka K, Traczewski W., Blaszczyk J. Oxygen metabolites in blood of pateints with gastric and duodenal ulcers. Hepatogastroenterol. 42:1995;246-249.
32. Mccall T. B., Palmer R. M., Moncada S. Induction of nos in rat peritoneal neutrophils and its inhibition by dexamethasone. Eur J Immunol. 21:1991;2523-2527.
33. O'Connor K. J., Moncada S. Glucocorticoids inhibit the induction of nos related cell damage in adenocarcinoma cells. Biochem Biophys Acta. 1097:1991;227-231.
34. Beckman J. S., Beckman T. W., Chen J., Marshall P. A., Freeman B. Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide. Proc Nat Acad Sci USA. 87:1990;1620-1624.
35. Huie R. E., Padmaja S. The reaction of nitric oxide with superoxide. Free Radical Res Comn. 18:1993;195-199.
36. Rubbo H., Radi R. R., Trujillo M. Nitric oxide regulation of superoxide and peroxynitrite dependent lipid peroxidation. Formation of novel nitrogen containing oxidised lipid derivatives. J Biol Chem. 269:1994;26066-26075.
37. Horrobin D. F. A biochemical basis for alcoholism and alcohol induced damage including fetal alcohol syndrome and cirrhosis: interference with essential fatty acid and prostaglandin metabolism. Med Hypotheses. 6:1980;929-942.
38. Das U. N. Essential fatty acids: biology and clinical implications. Asia Pacific J Pharmacol. 6:1991;317-330.
39. Foucher C., Largrost L., Maupoil V., Le-Meste M., Rochette L., Gambet P. Alterations of lipoprotein fluidity by non-esterified fatty acids known to affect cholesterol ester transfer protein activity. An electron spin resonance study. Eu J Biochem. 236:1996;436-442.
40. Ginsberg B. H., Chatterjee P., Yorek M. A. Insulin sensitivity is increased in friend erthroleukemia cells enriched in polyunsaturated fatty acid. Receptor. 1:1991;155-166.
41. Thompson L., Cockayne A., Spiller R. C. Inhibitory effect of polyunsaturated fatty acids on the growth of helicobacter pylori: a possible explaination for the effect of diet on peptic ulceration. Gut. 35:1994;1557-1561.
42. Das U. N., Kumar K. V., Ramanjaneyulu E., Nayana Joshi., Dixit V. K. Essential fatty acids and their metabolites in duodenal ulcer. Med. Sci. Res. 22:1994;423-425.