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Volumn 10, Issue 2, 2011, Pages 133-140

Hydrogen sulfide-based therapies: Focus on H2S releasing NSAIDs

Author keywords

Arthritis; Aspirin; CINODs; Coxibs; Cyclooxygeneases; Diclofenac; Hydrogen sulfide; Lipoxin; Naproxen; Nitric oxide; Non steroidal anti inflammatory drugs

Indexed keywords

2 (6 METHOXYNAPHTHALEN 2 YL)PROPIONIC ACID 4 THIOCARBAMOYLPHENYL ESTER; 2 [(2,6 DICHLOROPHENYL)AMINO]BENZENEACETIC ACID 4 (3H 1,2 DITHIOL 3 THION 5 YL)PHENYL ESTER; ACETYLSALICYLIC ACID DERIVATIVE; ACS 14; ACS 15; ACS 21; ACS 6; ATB 337; ATB 343; ATB 345; ATB 346; AZ 3582; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; DICLOFENAC; DICLOFENAC DERIVATIVE; HYDROGEN SULFIDE; NAPROXCINOD; NAPROXEN; NAPROXEN DERIVATIVE; NONSTEROID ANTIINFLAMMATORY AGENT; PROSTAGLANDIN; PROSTAGLANDIN SYNTHASE INHIBITOR; UNCLASSIFIED DRUG;

EID: 79952747333     PISSN: 18715281     EISSN: None     Source Type: Journal    
DOI: 10.2174/187152811794776213     Document Type: Article
Times cited : (30)

References (55)
  • 1
    • 34547689191 scopus 로고    scopus 로고
    • Drug-induced injury in the gastrointestinal tract: Clinical and pathologic considerations
    • Pusztaszeri, M.P.; Genta, R.M.; Cryer, B.L. Drug-induced injury in the gastrointestinal tract: clinical and pathologic considerations. Nat. Clin. Pract. Gastroenterol. Hepatol., 2007, 4(8), 442-453.
    • (2007) Nat. Clin. Pract. Gastroenterol. Hepatol , vol.4 , Issue.8 , pp. 442-453
    • Pusztaszeri, M.P.1    Genta, R.M.2    Cryer, B.L.3
  • 2
    • 0033577982 scopus 로고    scopus 로고
    • Gastrointestinal toxicity of nonsteroidal antiinflammatory drugs
    • Wolfe, M.M.; Lichtenstein, D.R.; Singh, G. Gastrointestinal toxicity of nonsteroidal antiinflammatory drugs. N. Engl. J. Med., 1999, 340(24), 1888-1899.
    • (1999) N. Engl. J. Med , vol.340 , Issue.24 , pp. 1888-1899
    • Wolfe, M.M.1    Lichtenstein, D.R.2    Singh, G.3
  • 3
    • 0242690224 scopus 로고    scopus 로고
    • COX-2 and beyond: Approaches to prostaglandin inhibition in human disease
    • FitzGerald, G.A. COX-2 and beyond: approaches to prostaglandin inhibition in human disease. Nat. Rev. Drug Discov., 2003, 2(11), 879-890.
    • (2003) Nat. Rev. Drug Discov , vol.2 , Issue.11 , pp. 879-890
    • Fitzgerald, G.A.1
  • 4
    • 36248956113 scopus 로고    scopus 로고
    • NSAIDs, Coxibs, CINOD and H2S-releasing NSAIDs, what lies beyond the horizon
    • Fiorucci, S.; Distrutti, E.; Santucci, L. NSAIDs, Coxibs, CINOD and H2S-releasing NSAIDs, what lies beyond the horizon? Dig. Liver Dis., 2007, 39(12), 1043-1051.
    • (2007) Dig. Liver Dis , vol.39 , Issue.12 , pp. 1043-1051
    • Fiorucci, S.1    Distrutti, E.2    Santucci, L.3
  • 5
    • 25644452810 scopus 로고    scopus 로고
    • Investigators of the Asociacion Espanola de Gastroenterologia (AEG). A nationwide study of mortality associated with hospital admission due to severe gastrointestinal events and those associated with nonsteroidal anti-inflammatory drug use
    • Lana, S.A.; Perez-Aisa, M.A.; Feu, F.; Ponce, J.; Saperas, E.; Santolaria, S.; Rodrigo, L.; Balanzo, J.; Bajador, E.; Almela, P.; Navarro, J.M.; Carballo, F.; Castro, M.; Quintero, E.; Investigators of the Asociacion Espanola de Gastroenterologia (AEG). A nationwide study of mortality associated with hospital admission due to severe gastrointestinal events and those associated with nonsteroidal anti-inflammatory drug use. Am. J. Gastroenterol., 2005, 700(8),1685-1693.
    • (2005) Am. J. Gastroenterol , vol.700 , Issue.8 , pp. 1685-1693
    • Lana, S.A.1    Perez-Aisa, M.A.2    Feu, F.3    Ponce, J.4    Saperas, E.5    Santolaria, S.6    Rodrigo, L.7    Balanzo, J.8    Bajador, E.9    Almela, P.10    Navarro, J.M.11    Carballo, F.12    Castro, M.13    Quintero, E.14
  • 7
    • 0029162250 scopus 로고
    • Misoprostol reduces serious gastrointestinal complications in patients with rheumatoid arthritis receiving nonsteroidal anti-inflammatory drugs. A randomized, double-blind, placebo-controlled trial
    • Silverstein, E.; Graham, D.Y.; Senior, J.R.; Davies, H.W.; Struthers B.J.; Bittman, R.M.; Geis, G.S. Misoprostol reduces serious gastrointestinal complications in patients with rheumatoid arthritis receiving nonsteroidal anti-inflammatory drugs. A randomized, double-blind, placebo-controlled trial. Ann. Intern. Med., 1995, 723(4), 241-249.
    • (1995) Ann. Intern. Med , vol.723 , Issue.4 , pp. 241-249
    • Silverstein, E.1    Graham, D.Y.2    Senior, J.R.3    Davies, H.W.4    Struthers, B.J.5    Bittman, R.M.6    Geis, G.S.7
  • 8
    • 0032510378 scopus 로고    scopus 로고
    • Omeprazole compared with misoprostol for ulcers associated with nonsteroidal antiinflammatory drugs. Omeprazole versus Misoprostol for NSAID-induced Ulcer Management (OMNIUM) Study Group
    • Hawkey, C.J.; Karrasch, J.A.; Szczepanski, L.; Walker, D.G.; Barkun, A.; Swannell, A.J.; Yeomans, N.D. Omeprazole compared with misoprostol for ulcers associated with nonsteroidal antiinflammatory drugs. Omeprazole versus Misoprostol for NSAID-induced Ulcer Management (OMNIUM) Study Group, N. Engl. J. Med.,1998, 338(11), 727-734.
    • (1998) N. Engl. J. Med , vol.338 , Issue.11 , pp. 727-734
    • Hawkey, C.J.1    Karrasch, J.A.2    Szczepanski, L.3    Walker, D.G.4    Barkun, A.5    Swannell, A.J.6    Yeomans, N.D.7
  • 9
    • 65549161327 scopus 로고    scopus 로고
    • The role of proton pump inhibitors in the management of upper gastrointestinal bleeding
    • Chan. F.K.L. The role of proton pump inhibitors in the management of upper gastrointestinal bleeding. Gastroenterol. Clin. North Am., 2009, 38,199-214.
    • (2009) Gastroenterol. Clin. North Am , vol.38 , pp. 199-214
    • Chan, F.K.L.1
  • 10
    • 65549113804 scopus 로고    scopus 로고
    • Prevention of nonsteroidal anti-inflammatory drug induced ulcers: Looking to the future. Gastroenterol
    • Fiorucci, S. Prevention of nonsteroidal anti-inflammatory drug induced ulcers: looking to the future. Gastroenterol. Clin. North Am., 2009, 38(2), 315-322.
    • (2009) Clin. North Am , vol.38 , Issue.2 , pp. 315-322
    • Fiorucci, S.1
  • 11
    • 0036562261 scopus 로고    scopus 로고
    • Potential cardioprotective actions of nitric oxide-releasing aspirin
    • Wallace, J.L.; Ignarro, L.J.; Fiorucci, S. Potential cardioprotective actions of nitric oxide-releasing aspirin. Nature Rev. Drug Discov., 2002, 7(5), 375-382.
    • (2002) Nature Rev. Drug Discov , vol.7 , Issue.5 , pp. 375-382
    • Wallace, J.L.1    Ignarro, L.J.2    Fiorucci, S.3
  • 12
    • 33750689471 scopus 로고    scopus 로고
    • Nitric oxide and cyclic GMP in cell signaling and drug development
    • Murad, F. Nitric oxide and cyclic GMP in cell signaling and drug development. N. Engl. J. Med., 2006, 355(19), 2003-2011.
    • (2006) N. Engl. J. Med , vol.355 , Issue.19 , pp. 2003-2011
    • Murad, F.1
  • 13
    • 0036845556 scopus 로고    scopus 로고
    • Two's company, three's a crowd: Can H2S be the third endogenous gaseous transmitter
    • Wang, R. Two's company, three's a crowd: can H2S be the third endogenous gaseous transmitter? FASEB J., 2002, 76(13), 1792-1798.
    • (2002) FASEB J , vol.76 , Issue.13 , pp. 1792-1798
    • Wang, R.1
  • 14
    • 35748959038 scopus 로고    scopus 로고
    • Hydrogen sulfide and its therapeutic potential
    • Szabo, C. Hydrogen sulfide and its therapeutic potential. Nat. Rev. Drug Discovery, 2007, 6(11), 917-935.
    • (2007) Nat. Rev. Drug Discovery , vol.6 , Issue.11 , pp. 917-935
    • Szabo, C.1
  • 15
    • 33745920516 scopus 로고    scopus 로고
    • The emerging roles of hydrogen sulfide in the gastrontestinal tract and liver
    • Fiorucci, S.; Distrutti, E.; Cirino, G.; Wallace, J. L. The emerging roles of hydrogen sulfide in the gastrontestinal tract and liver. Gastroenterology, 2006, 737(1), 259-272.
    • (2006) Gastroenterology , vol.737 , Issue.1 , pp. 259-272
    • Fiorucci, S.1    Distrutti, E.2    Cirino, G.3    Wallace, J.L.4
  • 16
    • 0025078185 scopus 로고
    • Gastric ulceration induced by nonsteroidal anti-inflammatory drugs is a neutrophil- dependent process
    • Fallace, J.L.; Keenan, C.M.; Granger, D.N. Gastric ulceration induced by nonsteroidal anti-inflammatory drugs is a neutrophil- dependent process. Am. J. Physiol., 1990, 259(3 Pt1), G462-G467.
    • (1990) Am. J. Physiol , vol.259 , Issue.3 Pt1
    • Fallace, J.L.1    Keenan, C.M.2    Granger, D.N.3
  • 17
    • 0028967384 scopus 로고
    • Role of tumor necrosis factor alpha release and leukocyte margination in indomethacin-induced gastric injury in rats
    • Santucci, L.; Fiorucci, S.; Di Matteo, F.M.; Morelli, A. Role of tumor necrosis factor alpha release and leukocyte margination in indomethacin-induced gastric injury in rats. Gastroenterology, 1995, 708(2), 393-401.
    • (1995) Gastroenterology , vol.708 , Issue.2 , pp. 393-401
    • Santucci, L.1    Fiorucci, S.2    Di Matteo, F.M.3    Morelli, A.4
  • 18
    • 0026720660 scopus 로고
    • Nitric oxide mediates rat mucosal vasodilatation induced by intragastric capsaicin
    • Whittle, B.J.; Lopez-Belmonte, J.; Moncada, S. Nitric oxide mediates rat mucosal vasodilatation induced by intragastric capsaicin. Eur. J. Pharmacol., 1992, 278(2-3), 339-41.
    • (1992) Eur. J. Pharmacol , vol.278 , Issue.2-3 , pp. 339-341
    • Whittle, B.J.1    Lopez-Belmonte, J.2    Moncada, S.3
  • 19
    • 0028182409 scopus 로고
    • Novel nonsteroidal anti-inflammatory drug derivatives with markedly reduced ulcerogenic properties in the rat
    • Wallace, J.L.; Reuter, B.; Cicala, C.; McKnight, W.; Grisham, M.B.; Cirino, G. Novel nonsteroidal anti-inflammatory drug derivatives with markedly reduced ulcerogenic properties in the rat. Gastroenterology, 1994, 707(1), 173-179.
    • (1994) Gastroenterology , vol.707 , Issue.1 , pp. 173-179
    • Wallace, J.L.1    Reuter, B.2    Cicala, C.3    McKnight, W.4    Grisham, M.B.5    Cirino, G.6
  • 20
    • 33745238041 scopus 로고    scopus 로고
    • Nitronaproxen: AZD 3582, HCT 3012, Naproxen Nitroxybutylester, NO-Naproxen
    • Anonymous
    • Anonymous. Nitronaproxen: AZD 3582, HCT 3012, Naproxen Nitroxybutylester, NO-Naproxen. Drugs R. D., 2006, 7(4), 262-266.
    • (2006) Drugs R. D , vol.7 , Issue.4 , pp. 262-266
  • 21
    • 33846184714 scopus 로고    scopus 로고
    • Gastrointestinal safety and anti-inflammatory effects of a hydrogen sulphide-releasing diclofenac derivative in the rat
    • Wallace, J.L.; Caliendo, G.; Santagada, V.; Cirino, G.; Fiorucci, S. Gastrointestinal safety and anti-inflammatory effects of a hydrogen sulphide-releasing diclofenac derivative in the rat. Gastroenterology, 2007, 732(1), 261-271.
    • (2007) Gastroenterology , vol.732 , Issue.1 , pp. 261-271
    • Wallace, J.L.1    Caliendo, G.2    Santagada, V.3    Cirino, G.4    Fiorucci, S.5
  • 25
    • 4344661128 scopus 로고    scopus 로고
    • TARGET Study Group. Comparison of lumiracoxib with naproxen and ibuprofen in the Therapeutic Arthritis Research and Gastrointestinal Event Trial (TARGET), reduction in ulcer complications: Randomised controlled trial
    • Schnitzer, T.J.; Burmester, G.R.; Mysler, E.; Hochberg, M.C.; Doherty, M.; Ehrsam, E.; Gitton, X.; Krammer, G.; Mellein, B.; Matchaba, P.; Gimona, A.; Hawkey, C.J.; TARGET Study Group. Comparison of lumiracoxib with naproxen and ibuprofen in the Therapeutic Arthritis Research and Gastrointestinal Event Trial (TARGET), reduction in ulcer complications: randomised controlled trial. Lancet, 2004, 364(9435), 665-674.
    • (2004) Lancet , vol.364 , Issue.9435 , pp. 665-674
    • Schnitzer, T.J.1    Burmester, G.R.2    Mysler, E.3    Hochberg, M.C.4    Doherty, M.5    Ehrsam, E.6    Gitton, X.7    Krammer, G.8    Mellein, B.9    Matchaba, P.10    Gimona, A.11    Hawkey, C.J.12
  • 28
    • 18344368896 scopus 로고    scopus 로고
    • Risk of hospitalization for myocardial infarction among users of rofecoxib, celecoxib, and other NSAIDs: A population-based case-control study
    • Johnsen, S.P.; Larsson, H.; Tarone, R.E.; McLaughlin, J.K.; Norgard, B.; Friis, S.; Sorensen, H.T. Risk of hospitalization for myocardial infarction among users of rofecoxib, celecoxib, and other NSAIDs: a population-based case-control study. Arch. Intern. Med., 2005, 765(9), 978-984.
    • (2005) Arch. Intern. Med , vol.765 , Issue.9 , pp. 978-984
    • Johnsen, S.P.1    Larsson, H.2    Tarone, R.E.3    McLaughlin, J.K.4    Norgard, B.5    Friis, S.6    Sorensen, H.T.7
  • 29
    • 9944262983 scopus 로고    scopus 로고
    • Risk of cardiovascular events and rofecoxib: Cumulative meta-analysis
    • Juni, P.; Nartey, L.; Reichenbach, S.; Sterchi, R.; Dieppe, P.A.; Egger, M. Risk of cardiovascular events and rofecoxib: cumulative meta-analysis. Lancet, 2004, 364(9450), 2021-2029.
    • (2004) Lancet , vol.364 , Issue.9450 , pp. 2021-2029
    • Juni, P.1    Nartey, L.2    Reichenbach, S.3    Sterchi, R.4    Dieppe, P.A.5    Egger, M.6
  • 31
    • 0141479985 scopus 로고    scopus 로고
    • Interaction of a selective cyclooxygenase-2 inhibitor with aspirin and NO-releasing aspirin in the human gastric mucosa
    • Fiorucci, S.; Santucci, L.; Wallace, J.L.; Sardina, M.; Romano, M.; del Soldato, P.; Morelli, A. Interaction of a selective cyclooxygenase-2 inhibitor with aspirin and NO-releasing aspirin in the human gastric mucosa. Proc. Natl. Acad. Sci. USA, 2003, 700(19), 10937-10941.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.700 , Issue.19 , pp. 10937-10941
    • Fiorucci, S.1    Santucci, L.2    Wallace, J.L.3    Sardina, M.4    Romano, M.5    del Soldato, P.6    Morelli, A.7
  • 32
    • 0038718727 scopus 로고    scopus 로고
    • Relative contribution of acetylated cyclo-oxygenase (COX)-2 and 5-lipooxygenase (LOX) in regulating gastric mucosal integrity and adaptation to aspirin
    • Fiorucci, S.; Distrutti, E.; de Lima, O.M.; Romano, M.; Mencarelli, A.; Barbanti, M.; Palazzini, E.; Morelli, A.; Wallace, J.L. Relative contribution of acetylated cyclo-oxygenase (COX)-2 and 5-lipooxygenase (LOX) in regulating gastric mucosal integrity and adaptation to aspirin. FASEB J., 2003, 7 7(9), 1171-1173.
    • (2003) FASEB J , vol.77 , Issue.9 , pp. 1171-1173
    • Fiorucci, S.1    Distrutti, E.2    de Lima, O.M.3    Romano, M.4    Mencarelli, A.5    Barbanti, M.6    Palazzini, E.7    Morelli, A.8    Wallace, J.L.9
  • 34
    • 0242329755 scopus 로고    scopus 로고
    • Gastrointestinal safety of AZD3582, a cyclooxygenase inhibiting nitric oxide donator: Proof of concept study in humans
    • Hawkey, C.; Jones, J.I.; Atherton, C.T.; Skelly, M.M.; Bebb, J.R.; Fagerholm, U.; Jonzon, B.; Karlsson, P.; Bjarnason, I.T. Gastrointestinal safety of AZD3582, a cyclooxygenase inhibiting nitric oxide donator: proof of concept study in humans. Gut, 2003, 52(11), 1537-1542.
    • (2003) Gut , vol.52 , Issue.11 , pp. 1537-1542
    • Hawkey, C.1    Jones, J.I.2    Atherton, C.T.3    Skelly, M.M.4    Bebb, J.R.5    Fagerholm, U.6    Jonzon, B.7    Karlsson, P.8    Bjarnason, I.T.9
  • 35
    • 14144252695 scopus 로고    scopus 로고
    • STAR Multinational Study Group. A randomised, placebo controlled, comparative trial of the gastrointestinal safety and efficacy of AZD3582 versus naproxen in osteoarthritis
    • Lohmander, L.S.; McKeith, D.; Svensson, O.; Malmenas, M.; Bolin, L.; Kalla, A.; Genti, G.; Szechinski, J.; Ramos-Remus, C.; STAR Multinational Study Group. A randomised, placebo controlled, comparative trial of the gastrointestinal safety and efficacy of AZD3582 versus naproxen in osteoarthritis. Ann. Rheum. Dis., 2005, 64(3), 449-456.
    • (2005) Ann. Rheum. Dis , vol.64 , Issue.3 , pp. 449-456
    • Lohmander, L.S.1    McKeith, D.2    Svensson, O.3    Malmenas, M.4    Bolin, L.5    Kalla, A.6    Genti, G.7    Szechinski, J.8    Ramos-Remus, C.9
  • 36
    • 33744496549 scopus 로고    scopus 로고
    • NO-NSAIDs: From inflammatory mediators to clinical readouts. Inflamm
    • Fiorucci, S.; Antonelli, E. NO-NSAIDs: from inflammatory mediators to clinical readouts. Inflamm. Allergy Drug Targets, 2006, 5(2), 121-131.
    • (2006) Allergy Drug Targets , vol.5 , Issue.2 , pp. 121-131
    • Fiorucci, S.1    Antonelli, E.2
  • 38
    • 77949379109 scopus 로고    scopus 로고
    • Markedly reduced toxicity of a hydrogen sulphide-releasing derivative of naproxen (ATB-346)
    • Wallace, J.L.; Caliendo, G.; Santagada, V.; Cirino, G. Markedly reduced toxicity of a hydrogen sulphide-releasing derivative of naproxen (ATB-346). Br. J. Pharmacol., 2010, 759(6), 1236-1246.
    • (2010) Br. J. Pharmacol , vol.759 , Issue.6 , pp. 1236-1246
    • Wallace, J.L.1    Caliendo, G.2    Santagada, V.3    Cirino, G.4
  • 39
    • 33845602529 scopus 로고    scopus 로고
    • Hydrogen sulfide is an endogenous modulator of leukocyte-mediated inflammation
    • Zanardo, R. C.; Brancaleone, V.; Distrutti, E.; Fiorucci, S.; Cirino, G.; Wallace, J. L. Hydrogen sulfide is an endogenous modulator of leukocyte-mediated inflammation. FASEB J., 2006, 20(12), 2118-2120.
    • (2006) FASEB J , vol.20 , Issue.12 , pp. 2118-2120
    • Zanardo, R.C.1    Brancaleone, V.2    Distrutti, E.3    Fiorucci, S.4    Cirino, G.5    Wallace, J.L.6
  • 41
    • 73449101844 scopus 로고    scopus 로고
    • Hydrogen sulfide-releasing NSAIDs attenuate neuroinflammation induced by microglial and astrocytic activation
    • Lee, M.; Sparatore, A.; Del Soldato, P.; McGeer, E.; McGeer, PL. Hydrogen sulfide-releasing NSAIDs attenuate neuroinflammation induced by microglial and astrocytic activation. Glia, 2010, 58(1), 103-113.
    • (2010) Glia , vol.58 , Issue.1 , pp. 103-113
    • Lee, M.1    Sparatore, A.2    Del Soldato, P.3    McGeer, E.4    McGeer, P.L.5
  • 43
    • 77950340742 scopus 로고    scopus 로고
    • Modulation of thiol homeostasis induced by H2S-releasing aspirin
    • Giustarini, D.; Del Soldato, P.; Sparatore, A.; Rossi, R. Modulation of thiol homeostasis induced by H2S-releasing aspirin. Free Radic. Biol. Med., 2010, 48(9), 1263-1272.
    • (2010) Free Radic. Biol. Med , vol.48 , Issue.9 , pp. 1263-1272
    • Giustarini, D.1    Del Soldato, P.2    Sparatore, A.3    Rossi, R.4
  • 45
    • 34547465319 scopus 로고    scopus 로고
    • Effect of S-diclofenac, a novel hydrogen sulfide releasing derivative, on carrageenan-induced hindpaw oedema formation in the rat
    • Sidhapuriwala, J.; Li, L.; Sparatore, A.; Bhatia, M.; Moore, P.K. Effect of S-diclofenac, a novel hydrogen sulfide releasing derivative, on carrageenan-induced hindpaw oedema formation in the rat. Eur. J. Pharmacol., 2007, 569(1-2), 149-154
    • (2007) Eur. J. Pharmacol , vol.569 , Issue.1-2 , pp. 149-154
    • Sidhapuriwala, J.1    Li, L.2    Sparatore, A.3    Bhatia, M.4    Moore, P.K.5
  • 46
    • 37549023785 scopus 로고    scopus 로고
    • Treatment with H2S-releasing diclofenac protects mice against acute pancreatitis-associated lung injury
    • Bhatia, M.; Sidhapuriwala, J.N.; Sparatore, A.; Moore, P.K. Treatment with H2S-releasing diclofenac protects mice against acute pancreatitis-associated lung injury. Shock, 2008, 29(1), 8488.
    • (2008) Shock , vol.29 , Issue.1 , pp. 8488
    • Bhatia, M.1    Sidhapuriwala, J.N.2    Sparatore, A.3    Moore, P.K.4
  • 47
    • 37849037631 scopus 로고    scopus 로고
    • The hydrogen sulphide-releasing derivative of diclofenac protects against ischaemia-reperfusion injury in the isolated rabbit heart
    • Rossoni, G.; Sparatore, A.; Tazzari, V.; Manfredi, B.; Del Soldato, P.; Berti, F. The hydrogen sulphide-releasing derivative of diclofenac protects against ischaemia-reperfusion injury in the isolated rabbit heart. Br. J. Pharmacol., 2008, 753(1), 100-109.
    • (2008) Br. J. Pharmacol , vol.753 , Issue.1 , pp. 100-109
    • Rossoni, G.1    Sparatore, A.2    Tazzari, V.3    Manfredi, B.4    Del Soldato, P.5    Berti, F.6
  • 48
    • 50849114157 scopus 로고    scopus 로고
    • Effect of S- diclofenac, a novel hydrogen sulfide releasing derivative inhibit rat vascular smooth muscle cell proliferation
    • Baskar, R.; Sparatore, A.; Del Soldato, P.; Moore, P.K. Effect of S- diclofenac, a novel hydrogen sulfide releasing derivative inhibit rat vascular smooth muscle cell proliferation. Eur. J. Pharmacol., 2008, 594(1-3), 1-8.
    • (2008) Eur. J. Pharmacol , vol.594 , Issue.1-3 , pp. 1-8
    • Baskar, R.1    Sparatore, A.2    Del Soldato, P.3    Moore, P.K.4
  • 50
    • 73449101844 scopus 로고    scopus 로고
    • Hydrogen sulfide-releasing NSAIDs attenuate neuroinflammation induced by microglial and astrocytic activation
    • Lee, M.; Sparatore, A.; Del Soldato, P.; McGeer, E.; McGeer, P.L. Hydrogen sulfide-releasing NSAIDs attenuate neuroinflammation induced by microglial and astrocytic activation. Glia, 2010, 58(1), 103-113.
    • (2010) Glia , vol.58 , Issue.1 , pp. 103-113
    • Lee, M.1    Sparatore, A.2    Del Soldato, P.3    McGeer, E.4    McGeer, P.L.5
  • 52
    • 77950340742 scopus 로고    scopus 로고
    • Modulation of thiol homeostasis induced by H2S-releasing aspirin
    • Giustarini, D.; Del Soldato, P.; Sparatore, A.; Rossi, R. Modulation of thiol homeostasis induced by H2S-releasing aspirin. Free Radic. Biol. Med., 2010, 48(9), 1263-1272.
    • (2010) Free Radic. Biol. Med , vol.48 , Issue.9 , pp. 1263-1272
    • Giustarini, D.1    Del Soldato, P.2    Sparatore, A.3    Rossi, R.4
  • 53
    • 54949089316 scopus 로고    scopus 로고
    • NSAID-induced gastrointestinal damage and the design of Gl-sparing NSAIDs
    • Wallace, J. L.; Vong, L. NSAID-induced gastrointestinal damage and the design of Gl-sparing NSAIDs. Curr. Opin. Invest. Drugs, 2008, 9(11), 1151-1156.
    • (2008) Curr. Opin. Invest. Drugs , vol.9 , Issue.11 , pp. 1151-1156
    • Wallace, J.L.1    Vong, L.2
  • 54
    • 34748841476 scopus 로고    scopus 로고
    • Hydrogen sulfide-releasing anti-inflammatory drugs
    • Wallace, J. L. Hydrogen sulfide-releasing anti-inflammatory drugs. Trends Pharmacol. Sci., 2007, 28(10), 501- 550.
    • (2007) Trends Pharmacol. Sci , vol.28 , Issue.10 , pp. 501-550
    • Wallace, J.L.1
  • 55
    • 79952746151 scopus 로고    scopus 로고
    • Hydrogen sulphide in heart and systemic circulation. Inflam
    • Bucci, M.; Cirino, C. Hydrogen sulphide in heart and systemic circulation. Inflam. Allergy Drug Targets, 2011, 70(2), 103-108.
    • (2011) Allergy Drug Targets , vol.70 , Issue.2 , pp. 103-108
    • Bucci, M.1    Cirino, C.2


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