Acute function of secreted amyloid precursor protein fragment APPsα in synaptic plasticity

Acta Neuropathologica

Volumn 129, Issue 1, 2015, Pages 21-37

  Hick, Meike ^a   Herrmann, Ulrike ^b   Weyer, Sascha W ^a   Mallm, Jan Philipp ^a   Tschäpe, Jakob Andreas ^a,f   Borgers, Marianne ^c   Mercken, Marc ^c   Roth, Fabian C ^a   Draguhn, Andreas ^a   Slomianka, Lutz ^d   Wolfer, David P ^d,e   Korte, Martin ^b,g   Müller, Ulrike C ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b TECHNICAL UNIVERSITY OF BRAUNSCHWEIG   (Germany)

^c JANSSEN RESEARCH AND DEVELOPMENT   (Belgium)

^d UNIVERSITY OF ZURICH   (Switzerland)

^e ETH ZURICH   (Switzerland)

^f Roche Diagnostics International   (Switzerland)

^g HELMHOLTZ CENTRE FOR INFECTION RESEARCH   (Germany)

Author keywords

Alzheimer; Amyloid precursor protein; APPs ; Hippocampus; Learning and memory; LTP; Synaptic plasticity

Indexed keywords

AMYLOID PRECURSOR PROTEIN; APLP2 PROTEIN, MOUSE; APPSALPHA PROTEIN, MOUSE; PEPTIDE FRAGMENT; RECOMBINANT PROTEIN;

ANIMAL; DENDRITE; FEMALE; GENETICS; HIPPOCAMPUS; KNOCKOUT MOUSE; MALE; MAZE TEST; METABOLISM; MOTOR ACTIVITY; NERVE CELL PLASTICITY; NEURITE; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; SPATIAL MEMORY; SYNAPSE;

AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; DENDRITES; FEMALE; HIPPOCAMPUS; MALE; MAZE LEARNING; MICE, KNOCKOUT; MOTOR ACTIVITY; NEURITES; NEURONAL PLASTICITY; PEPTIDE FRAGMENTS; RECOMBINANT PROTEINS; SPATIAL MEMORY; SYNAPSES;

EID: 84930378369     PISSN: 00016322     EISSN: 14320533     Source Type: Journal    
DOI: 10.1007/s00401-014-1368-x     Document Type: Article

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