Impact of the F508del mutation on ovine CFTR, a Cl- channel with enhanced conductance and ATP-dependent gating

Journal of Physiology

Volumn 593, Issue 11, 2015, Pages 2427-2446

  Cai, Zhiwei ^a   Palmai Pallag, Timea ^b,f   Khuituan, Pissared ^a,c   Mutolo, Michael J ^b   Boinot, Clément ^d   Liu, Beihui ^a   Scott Ward, Toby S ^a   Callebaut, Isabelle ^e   Harris, Ann ^b   Sheppard, David N ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

^b NORTHWESTERN UNIVERSITY   (United States)

^c Mahidol University   (Thailand)

^d UNIVERSITÉ DE POITIERS   (France)

^e UNIVERSITÉ PIERRE ET MARIE CURIE   (France)

^f UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; CHLORIDE CHANNEL; COMPLEMENTARY DNA; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; GLIBENCLAMIDE; PHLOXINE;

ANIMAL CELL; ARTICLE; CHANNEL GATING; CHLORIDE CURRENT; CHO CELL LINE; CONDUCTANCE; CONTROLLED STUDY; CYSTIC FIBROSIS; F508DEL MUTATION; GENETIC TRANSFECTION; HEK293 CELL LINE; HUMAN; HUMAN CELL; MUTATION; NONHUMAN; PATCH CLAMP TECHNIQUE; PHYLOGENY; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; PROTEIN STRUCTURE; SHEEP; SITE DIRECTED MUTAGENESIS; WESTERN BLOTTING; ANIMAL; CHEMISTRY; CRICETULUS; GENETICS; MOLECULAR MODEL; PHYSIOLOGY;

ADENOSINE TRIPHOSPHATE; ANIMALS; CHO CELLS; CRICETULUS; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; HEK293 CELLS; HUMANS; ION CHANNEL GATING; MODELS, MOLECULAR; MUTATION; SHEEP;

EID: 84929956909     PISSN: 00223751     EISSN: 14697793     Source Type: Journal    
DOI: 10.1113/JP270227     Document Type: Article

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