-
1
-
-
0034705293
-
Structural biology of Rad50 ATPase: ATP-driven conformational control in DNA double-strand break repair and the ABC-ATPase superfamily
-
Hopfner KP, et al. (2000) Structural biology of Rad50 ATPase: ATP-driven conformational control in DNA double-strand break repair and the ABC-ATPase superfamily. Cell 101:789-800.
-
(2000)
Cell
, vol.101
, pp. 789-800
-
-
Hopfner, K.P.1
-
2
-
-
0036342413
-
ATP binding to the motor domain from an ABC transporter drives formation of a nucleotide sandwich dimer
-
Smith PC, et al. (2002) ATP binding to the motor domain from an ABC transporter drives formation of a nucleotide sandwich dimer. Mol Cell 10:139-149.
-
(2002)
Mol Cell
, vol.10
, pp. 139-149
-
-
Smith, P.C.1
-
3
-
-
0242321011
-
Formation of the productive ATP-Mg2+-bound dimer of GlcV, an ABC-ATPase from Sulfolobus solfataricus
-
Verdon G, et al. (2003) Formation of the productive ATP-Mg2+-bound dimer of GlcV, an ABC-ATPase from Sulfolobus solfataricus. J Mol Biol 334:255-267.
-
(2003)
J Mol Biol
, vol.334
, pp. 255-267
-
-
Verdon, G.1
-
4
-
-
0037077296
-
Cooperative, ATP-dependent association of the nucleotide binding cassettes during the catalytic cycle of ATP-binding cassette transporters
-
Moody JE, Millen L, Binns D, Hunt JF, Thomas PJ (2002) Cooperative, ATP-dependent association of the nucleotide binding cassettes during the catalytic cycle of ATP-binding cassette transporters. J Biol Chem 277:21111-21114.
-
(2002)
J Biol Chem
, vol.277
, pp. 21111-21114
-
-
Moody, J.E.1
Millen, L.2
Binns, D.3
Hunt, J.F.4
Thomas, P.J.5
-
5
-
-
0038711772
-
The ATP hydrolysis cycle of the nucleotide-binding domain of the mitochondrial ATP-binding cassette transporter Mdl1p
-
Janas E, et al. (2003) The ATP hydrolysis cycle of the nucleotide-binding domain of the mitochondrial ATP-binding cassette transporter Mdl1p. J Biol Chem 278:26862-26869.
-
(2003)
J Biol Chem
, vol.278
, pp. 26862-26869
-
-
Janas, E.1
-
6
-
-
33646541093
-
The occluded nucleotide conformation of p-glycoprotein
-
Tombline G, Senior AE (2005) The occluded nucleotide conformation of p-glycoprotein. J Bioenerg Biomembr 37:497-500.
-
(2005)
J Bioenerg Biomembr
, vol.37
, pp. 497-500
-
-
Tombline, G.1
Senior, A.E.2
-
7
-
-
0024424270
-
Identification of the cystic fibrosis gene: Cloning and characterization of complementary DNA
-
Riordan JR, et al. (1989) Identification of the cystic fibrosis gene: Cloning and characterization of complementary DNA. Science 245:1066-1073.
-
(1989)
Science
, vol.245
, pp. 1066-1073
-
-
Riordan, J.R.1
-
8
-
-
42049096734
-
CLC-0 and CFTR: Chloride channels evolved from transporters
-
Chen TY, Hwang TC (2008) CLC-0 and CFTR: Chloride channels evolved from transporters. Physiol Rev 88:351-387.
-
(2008)
Physiol Rev
, vol.88
, pp. 351-387
-
-
Chen, T.Y.1
Hwang, T.C.2
-
9
-
-
0029117303
-
Conformational states of CFTR associated with channel gating: The role ATP binding and hydrolysis
-
Gunderson KL, Kopito RR (1995) Conformational states of CFTR associated with channel gating: The role ATP binding and hydrolysis. Cell 82:231-239.
-
(1995)
Cell
, vol.82
, pp. 231-239
-
-
Gunderson, K.L.1
Kopito, R.R.2
-
10
-
-
0030668944
-
Block by MOPS reveals a conformation change in the CFTR pore produced by ATP hydrolysis
-
Ishihara H, Welsh MJ (1997) Block by MOPS reveals a conformation change in the CFTR pore produced by ATP hydrolysis. Am J Physiol 273:C1278-C1289.
-
(1997)
Am J Physiol
, vol.273
-
-
Ishihara, H.1
Welsh, M.J.2
-
11
-
-
0032954806
-
Gating of cystic fibrosis transmembrane conductance regulator chloride channels by adenosine triphosphate hydrolysis. Quantitative analysis of a cyclic gating scheme
-
Zeltwanger S, Wang F, Wang GT, Gillis KD, Hwang TC (1999) Gating of cystic fibrosis transmembrane conductance regulator chloride channels by adenosine triphosphate hydrolysis. Quantitative analysis of a cyclic gating scheme. J Gen Physiol 113:541-554.
-
(1999)
J Gen Physiol
, vol.113
, pp. 541-554
-
-
Zeltwanger, S.1
Wang, F.2
Wang, G.T.3
Gillis, K.D.4
Hwang, T.C.5
-
12
-
-
0028174962
-
Coupling of CFTR Cl- channel gating to an ATP hydrolysis cycle
-
Baukrowitz T, Hwang TC, Nairn AC, Gadsby DC (1994) Coupling of CFTR Cl- channel gating to an ATP hydrolysis cycle. Neuron 12:473-482.
-
(1994)
Neuron
, vol.12
, pp. 473-482
-
-
Baukrowitz, T.1
Hwang, T.C.2
Nairn, A.C.3
Gadsby, D.C.4
-
13
-
-
0028340159
-
Regulation of the gating of cystic fibrosis transmembrane conductance regulator C1 channels by phosphorylation and ATP hydrolysis
-
Hwang TC, Nagel G, Nairn AC, Gadsby DC (1994) Regulation of the gating of cystic fibrosis transmembrane conductance regulator C1 channels by phosphorylation and ATP hydrolysis. Proc Natl Acad Sci USA 91:4698-4702.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 4698-4702
-
-
Hwang, T.C.1
Nagel, G.2
Nairn, A.C.3
Gadsby, D.C.4
-
14
-
-
0028906612
-
The two nucleotide-binding domains of cystic fibrosis transmembrane conductance regulator (CFTR) have distinct functions in controlling channel activity
-
Carson MR, Travis SM, Welsh MJ (1995) The two nucleotide-binding domains of cystic fibrosis transmembrane conductance regulator (CFTR) have distinct functions in controlling channel activity. J Biol Chem 270:1711-1717.
-
(1995)
J Biol Chem
, vol.270
, pp. 1711-1717
-
-
Carson, M.R.1
Travis, S.M.2
Welsh, M.J.3
-
15
-
-
0028070453
-
Effects of pyrophosphate and nucleotide analogs suggest a role for ATP hydrolysis in cystic fibrosis transmembrane regulator channel gating
-
Gunderson KL, Kopito RR (1994) Effects of pyrophosphate and nucleotide analogs suggest a role for ATP hydrolysis in cystic fibrosis transmembrane regulator channel gating. J Biol Chem 269:19349-19353.
-
(1994)
J Biol Chem
, vol.269
, pp. 19349-19353
-
-
Gunderson, K.L.1
Kopito, R.R.2
-
16
-
-
0037246832
-
On the mechanism of MgATP-dependent gating of CFTR Cl- channels
-
Vergani P, Nairn AC, Gadsby DC (2003) On the mechanism of MgATP-dependent gating of CFTR Cl- channels. J Gen Physiol 121:17-36.
-
(2003)
J Gen Physiol
, vol.121
, pp. 17-36
-
-
Vergani, P.1
Nairn, A.C.2
Gadsby, D.C.3
-
17
-
-
0037013262
-
The first nucleotide binding domain of cystic fibrosis transmembrane conductance regulator is a site of stable nucleotide interaction, whereas the second is a site of rapid turnover
-
Aleksandrov L, Aleksandrov AA, Chang XB, Riordan JR (2002) The first nucleotide binding domain of cystic fibrosis transmembrane conductance regulator is a site of stable nucleotide interaction, whereas the second is a site of rapid turnover. J Biol Chem 277:15419-15425.
-
(2002)
J Biol Chem
, vol.277
, pp. 15419-15425
-
-
Aleksandrov, L.1
Aleksandrov, A.A.2
Chang, X.B.3
Riordan, J.R.4
-
18
-
-
0141513675
-
Prolonged nonhydrolytic interaction of nucleotide with CFTR's NH2-terminal nucleotide binding domain and its role in channel gating
-
Basso C, Vergani P, Nairn AC, Gadsby DC (2003) Prolonged nonhydrolytic interaction of nucleotide with CFTR's NH2-terminal nucleotide binding domain and its role in channel gating. J Gen Physiol 122:333-348.
-
(2003)
J Gen Physiol
, vol.122
, pp. 333-348
-
-
Basso, C.1
Vergani, P.2
Nairn, A.C.3
Gadsby, D.C.4
-
19
-
-
14544300522
-
CFTR channel opening by ATPdriven tight dimerization of its nucleotide-binding domains
-
Vergani P, Lockless SW, Nairn AC, Gadsby DC (2005) CFTR channel opening by ATPdriven tight dimerization of its nucleotide-binding domains. Nature 433:876-880.
-
(2005)
Nature
, vol.433
, pp. 876-880
-
-
Vergani, P.1
Lockless, S.W.2
Nairn, A.C.3
Gadsby, D.C.4
-
21
-
-
0033514315
-
Walker mutations reveal loose relationship between catalytic and channel-gating activities of purified CFTR (cystic fibrosis transmembrane conductance regulator)
-
Ramjeesingh M, et al. (1999) Walker mutations reveal loose relationship between catalytic and channel-gating activities of purified CFTR (cystic fibrosis transmembrane conductance regulator). Biochemistry 38:1463-1468.
-
(1999)
Biochemistry
, vol.38
, pp. 1463-1468
-
-
Ramjeesingh, M.1
-
22
-
-
0032503962
-
Regulation of CFTR ion channel gating by MgATP
-
Aleksandrov AA, Riordan JR (1998) Regulation of CFTR ion channel gating by MgATP. FEBS Lett 431:97-101.
-
(1998)
FEBS Lett
, vol.431
, pp. 97-101
-
-
Aleksandrov, A.A.1
Riordan, J.R.2
-
23
-
-
67649659825
-
Relationship between nucleotide binding and ion channel gating in cystic fibrosis transmembrane conductance regulator
-
Aleksandrov AA, Cui L, Riordan JR (2009) Relationship between nucleotide binding and ion channel gating in cystic fibrosis transmembrane conductance regulator. J Physiol 587:2875-2886.
-
(2009)
J Physiol
, vol.587
, pp. 2875-2886
-
-
Aleksandrov, A.A.1
Cui, L.2
Riordan, J.R.3
-
25
-
-
0028265949
-
Effect of ATP concentration on CFTR Cl- channels: A kinetic analysis of channel regulation
-
Winter MC, Sheppard DN, Carson MR, Welsh MJ (1994) Effect of ATP concentration on CFTR Cl- channels: A kinetic analysis of channel regulation. Biophys J 66:1398-1403.
-
(1994)
Biophys J
, vol.66
, pp. 1398-1403
-
-
Winter, M.C.1
Sheppard, D.N.2
Carson, M.R.3
Welsh, M.J.4
-
26
-
-
33646165887
-
Statistical evaluation of ion-channel gating models based on distributions of log-likelihood ratios
-
Csanády L (2006) Statistical evaluation of ion-channel gating models based on distributions of log-likelihood ratios. Biophys J 90:3523-3545.
-
(2006)
Biophys J
, vol.90
, pp. 3523-3545
-
-
Csanády, L.1
-
27
-
-
0032584289
-
Mutations in either nucleotide-binding site of P-glycoprotein (Mdr3) prevent vanadate trapping of nucleotide at both sites
-
Urbatsch IL, Beaudet L, Carrier I, Gros P (1998) Mutations in either nucleotide-binding site of P-glycoprotein (Mdr3) prevent vanadate trapping of nucleotide at both sites. Biochemistry 37:4592-4602.
-
(1998)
Biochemistry
, vol.37
, pp. 4592-4602
-
-
Urbatsch, I.L.1
Beaudet, L.2
Carrier, I.3
Gros, P.4
-
28
-
-
0345583699
-
Both ATP sites of human P-glycoprotein are essential but not symmetric
-
Hrycyna CA, et al. (1999) Both ATP sites of human P-glycoprotein are essential but not symmetric. Biochemistry 38:13887-13899.
-
(1999)
Biochemistry
, vol.38
, pp. 13887-13899
-
-
Hrycyna, C.A.1
-
29
-
-
33845422375
-
Conserved Asp327 of walker B motif in the N-terminal nucleotide binding domain (NBD-1) of Cdr1p of Candida albicans has acquired a new role in ATP hydrolysis
-
Rai V, et al. (2006) Conserved Asp327 of walker B motif in the N-terminal nucleotide binding domain (NBD-1) of Cdr1p of Candida albicans has acquired a new role in ATP hydrolysis. Biochemistry 45:14726-14739.
-
(2006)
Biochemistry
, vol.45
, pp. 14726-14739
-
-
Rai, V.1
-
30
-
-
17044401724
-
CFTR gating II: Effects of nucleotide binding on the stability of open states
-
Bompadre SG, et al. (2005) CFTR gating II: Effects of nucleotide binding on the stability of open states. J Gen Physiol 125:377-394.
-
(2005)
J Gen Physiol
, vol.125
, pp. 377-394
-
-
Bompadre, S.G.1
-
31
-
-
0032542358
-
Crystal structure of the ATP-binding subunit of an ABC transporter
-
Hung LW, et al. (1998) Crystal structure of the ATP-binding subunit of an ABC transporter. Nature 396:703-707.
-
(1998)
Nature
, vol.396
, pp. 703-707
-
-
Hung, L.W.1
-
32
-
-
0036521974
-
Mutation of Walker-A lysine 464 in cystic fibrosis transmembrane conductance regulator reveals functional interaction between its nucleotide-binding domains
-
Powe AC, Jr, Al-Nakkash L, Li M, Hwang TC (2002) Mutation of Walker-A lysine 464 in cystic fibrosis transmembrane conductance regulator reveals functional interaction between its nucleotide-binding domains. J Physiol 539:333-346.
-
(2002)
J Physiol
, vol.539
, pp. 333-346
-
-
Powe Jr, A.C.1
Al-Nakkash, L.2
Li, M.3
Hwang, T.C.4
-
33
-
-
0033817333
-
Severed channels probe regulation of gating of cystic fibrosis transmembrane conductance regulator by its cytoplasmic domains
-
Csanády L, et al. (2000) Severed channels probe regulation of gating of cystic fibrosis transmembrane conductance regulator by its cytoplasmic domains. J Gen Physiol 116:477-500.
-
(2000)
J Gen Physiol
, vol.116
, pp. 477-500
-
-
Csanády, L.1
-
34
-
-
0020627803
-
Successive openings of the same acetylcholine receptor channel are correlated in open time
-
Jackson MB, Wong BS, Morris CE, Lecar H, Christian CN (1983) Successive openings of the same acetylcholine receptor channel are correlated in open time. Biophys J 42:109-114.
-
(1983)
Biophys J
, vol.42
, pp. 109-114
-
-
Jackson, M.B.1
Wong, B.S.2
Morris, C.E.3
Lecar, H.4
Christian, C.N.5
-
35
-
-
0020973067
-
Burst kinetics of single calcium-activated potassium channels in cultured rat muscle
-
Magleby KL, Pallotta BS (1983) Burst kinetics of single calcium-activated potassium channels in cultured rat muscle. J Physiol 344:605-623.
-
(1983)
J Physiol
, vol.344
, pp. 605-623
-
-
Magleby, K.L.1
Pallotta, B.S.2
-
36
-
-
17144456826
-
Rapid kinetic analysis of multichannel records by a simultaneous fit to all dwell-time histograms
-
Csanády L (2000) Rapid kinetic analysis of multichannel records by a simultaneous fit to all dwell-time histograms. Biophys J 78:785-799.
-
(2000)
Biophys J
, vol.78
, pp. 785-799
-
-
Csanády, L.1
-
37
-
-
33750499982
-
Thermodynamics of CFTR channel gating: A spreading conformational change initiates an irreversible gating cycle
-
Csanády L, Nairn AC, Gadsby DC (2006) Thermodynamics of CFTR channel gating: A spreading conformational change initiates an irreversible gating cycle. J Gen Physiol 128:523-533.
-
(2006)
J Gen Physiol
, vol.128
, pp. 523-533
-
-
Csanády, L.1
Nairn, A.C.2
Gadsby, D.C.3
|